product summary
company name :
Abcepta
product type :
antibody
product name :
LC3 Antibody (APG8B) (N-term)-24 citations
catalog :
AP1802a
quantity :
0.1 mg
price :
235.00 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; rat; 1:100; loading ...; tbl 1
Kim J, Hyun H, Min S, Kang T. Sustained HSP25 Expression Induces Clasmatodendrosis via ER Stress in the Rat Hippocampus. Front Cell Neurosci. 2017;11:47 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 6c
  • western blot; human; loading ...; fig 1b
Sun A, Wei J, Childress C, Shaw J, Peng K, Shao G, et al. The E3 ubiquitin ligase NEDD4 is an LC3-interactive protein and regulates autophagy. Autophagy. 2017;13:522-537 pubmed publisher
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 4
Buckingham E, Jarosinski K, Jackson W, Carpenter J, Grose C. Exocytosis of Varicella-Zoster Virus Virions Involves a Convergence of Endosomal and Autophagy Pathways. J Virol. 2016;90:8673-85 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:25; fig 7
Ruiz A, Rockfield S, Taran N, Haller E, Engelman R, Flores I, et al. Effect of hydroxychloroquine and characterization of autophagy in a mouse model of endometriosis. Cell Death Dis. 2016;7:e2059 pubmed publisher
Su W, Yu W, Huang S, Lai M. Ubiquitination of the Cytoplasmic Domain of Influenza A Virus M2 Protein Is Crucial for Production of Infectious Virus Particles. J Virol. 2018;92: pubmed publisher
Lin Q, Dai Q, Meng H, Sun A, Wei J, Peng K, et al. The HECT E3 ubiquitin ligase NEDD4 interacts with and ubiquitylates SQSTM1 for inclusion body autophagy. J Cell Sci. 2017;130:3839-3850 pubmed publisher
Adams O, Dislich B, Berezowska S, Schläfli A, Seiler C, Kröll D, et al. Prognostic relevance of autophagy markers LC3B and p62 in esophageal adenocarcinomas. Oncotarget. 2016;7:39241-39255 pubmed publisher
Li W, Xiong L, Shi X, Xiao L, Qi G, Meng C. IKK?/NF?Bp65 activated by interleukin-13 targets the autophagy-related genes LC3B and beclin 1 in fibroblasts co-cultured with breast cancer cells. Exp Ther Med. 2016;11:1259-1264 pubmed
Bajsarowicz K, Ahn M, Ackerman L, Dearmond B, Carlson G, Dearmond S. A brain aggregate model gives new insights into the pathobiology and treatment of prion diseases. J Neuropathol Exp Neurol. 2012;71:449-66 pubmed publisher
product information
Catalog Number :
AP1802a
Product Name :
LC3 Antibody (APG8B) (N-term)-24 citations
Host Species :
Rabbit
Clonality :
Polyclonal
Product Type :
Primary Antibody
Size :
0.1 mg
List Price :
235.00 USD
Clone :
RB1999
Isotype :
Rabbit Ig
Product Description :
Purified Rabbit Polyclonal Antibody (Pab)
CrossReactivity :
H
Background :
PDGFA is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth.
Immunogen :
This PDGFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from amino acids 60-90 of human PDGFA.
Buffer :
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Concentration :
0.25 mg/ml
Application Summary :
WB, IHC, E
Storage :
Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles.
more info or order :
company information
Abcepta
10320 Camino Santa Fe Suite G
San Diego, CA 92121
sales@abcepta.com
https://www.abcepta.com
(888) 735-7227
headquarters: USA