LC3 Antibody (APG8) | Abcepta AM1800a product information

product summary

company name :

Abcepta

product type :

antibody

product name :

LC3 Antibody (APG8)

catalog :

AM1800a

quantity :

0.1 mg

price :

235.00 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

more info or order :

Abcepta product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:500; fig 4	Hu Z, Zhong Z, Huang S, Wen H, Chen X, Chu H, et al. Decreased expression of Beclin?1 is significantly associated with a poor prognosis in oral tongue squamous cell carcinoma. Mol Med Rep. 2016;14:1567-73 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:200; fig 9	Cho S, Yun S, Jo C, Lee D, Choi K, Song J, et al. SUMO1 promotes AÎ² production via the modulation of autophagy. Autophagy. 2015;11:100-12 pubmed publisher
	Xing S, Zhang Y, Li J, Zhang J, Li Y, Dang C, et al. Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction. Autophagy. 2012;8:63-76 pubmed publisher
	Hsin I, Ou C, Wu T, Jan M, Wu M, Chiu L, et al. GMI, an immunomodulatory protein from Ganoderma microsporum, induces autophagy in non-small cell lung cancer cells. Autophagy. 2011;7:873-82 pubmed
	Baras A, Moskaluk C. Intracellular localization of GASP/ECOP/VOPP1. J Mol Histol. 2010;41:153-64 pubmed publisher

product information

Catalog Number :

AM1800a

Product Name :

LC3 Antibody (APG8)

Host Species :

Mouse

Clonality :

Monoclonal

Product Type :

Primary Antibody

Size :

0.1 mg

List Price :

235.00 USD

Clone :

60CT77.1.1

Isotype :

IgG1,k

Product Description :

Mouse Monoclonal Antibody (Mab)

CrossReactivity :

Background :

Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation (By similarity).

ALTnames :

Homeobox protein NANOG;NANOG;

Immunogen :

This NANOG monoclonal antibody is generated from mouse immunized with NANOG recombinant protein.

Buffer :

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Concentration :

0.25 mg/ml

Application Summary :

WB, E

Storage :

Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles.

more info or order :

Abcepta product webpage