This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-VEGF Receptor 1 antibody [Flt-1/EWC]
catalog :
ab9540
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Flt-1/EWC
reactivity :
human, mouse, rat, dogs
application :
western blot, ELISA, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:800; loading ...; fig 5a
Chen Q, Huang M, Wu J, Jiang Q, Zheng X. Exosomes isolated from the plasma of remote ischemic conditioning rats improved cardiac function and angiogenesis after myocardial infarction through targeting Hsp70. Aging (Albany NY). 2020;12:3682-3693 pubmed publisher
  • western blot; mouse; fig s3
Semba H, Takeda N, Isagawa T, Sugiura Y, Honda K, Wake M, et al. HIF-1?-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity. Nat Commun. 2016;7:11635 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:300; fig 2d
Pinheiro C, Garcia E, Morais Santos F, Moreira M, Almeida F, Jubé L, et al. Reprogramming energy metabolism and inducing angiogenesis: co-expression of monocarboxylate transporters with VEGF family members in cervical adenocarcinomas. BMC Cancer. 2015;15:835 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:300; fig 2
Pinheiro C, Garcia E, Morais Santos F, Scapulatempo Neto C, Mafra A, Steenbergen R, et al. Lactate transporters and vascular factors in HPV-induced squamous cell carcinoma of the uterine cervix. BMC Cancer. 2014;14:751 pubmed publisher
  • western blot; mouse
Luo L, Uehara H, Zhang X, Das S, Olsen T, Holt D, et al. Photoreceptor avascular privilege is shielded by soluble VEGF receptor-1. elife. 2013;2:e00324 pubmed publisher
Samaranayake H, Pikkarainen J, Wirth T, Stedt H, Lesch H, Dragneva G, et al. Soluble vascular endothelial growth factor receptor-1 improves therapeutic efficacy of suicide gene therapy in an angiogenesis-independent manner. Hum Gene Ther. 2014;25:942-54 pubmed publisher
Suspitsin E, Kashyap A, Shelekhova K, Sokolenko A, Kuligina E, Iyevleva A, et al. Evidence for angiogenesis-independent contribution of VEGFR1 (FLT1) in gastric cancer recurrence. Med Oncol. 2013;30:644 pubmed publisher
Matjila M, Millar R, Van der Spuy Z, Katz A. The differential expression of Kiss1, MMP9 and angiogenic regulators across the feto-maternal interface of healthy human pregnancies: implications for trophoblast invasion and vessel development. PLoS ONE. 2013;8:e63574 pubmed publisher
Xu C, Wu X, Zhu J. VEGF promotes proliferation of human glioblastoma multiforme stem-like cells through VEGF receptor 2. ScientificWorldJournal. 2013;2013:417413 pubmed publisher
Hur K, Toiyama Y, Takahashi M, Balaguer F, Nagasaka T, Koike J, et al. MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis. Gut. 2013;62:1315-26 pubmed publisher
Ramírez M, Wu Z, Moreno Carranza B, Jeziorski M, Arnold E, Díaz Lezama N, et al. Vasoinhibin gene transfer by adenoassociated virus type 2 protects against VEGF- and diabetes-induced retinal vasopermeability. Invest Ophthalmol Vis Sci. 2011;52:8944-50 pubmed publisher
Sela S, Natanson Yaron S, Zcharia E, Vlodavsky I, Yagel S, Keshet E. Local retention versus systemic release of soluble VEGF receptor-1 are mediated by heparin-binding and regulated by heparanase. Circ Res. 2011;108:1063-70 pubmed publisher
Doehn U, Hauge C, Frank S, Jensen C, Duda K, Nielsen J, et al. RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells. Mol Cell. 2009;35:511-22 pubmed publisher
Thomas C, Andrews J, Raikwar N, Kelley E, Herse F, Dechend R, et al. A recently evolved novel trophoblast-enriched secreted form of fms-like tyrosine kinase-1 variant is up-regulated in hypoxia and preeclampsia. J Clin Endocrinol Metab. 2009;94:2524-30 pubmed publisher
Sela S, Itin A, Natanson Yaron S, Greenfield C, Goldman Wohl D, Yagel S, et al. A novel human-specific soluble vascular endothelial growth factor receptor 1: cell-type-specific splicing and implications to vascular endothelial growth factor homeostasis and preeclampsia. Circ Res. 2008;102:1566-74 pubmed publisher
Gu Y, Lewis D, Wang Y. Placental productions and expressions of soluble endoglin, soluble fms-like tyrosine kinase receptor-1, and placental growth factor in normal and preeclamptic pregnancies. J Clin Endocrinol Metab. 2008;93:260-6 pubmed
Cindrova Davies T, Yung H, Johns J, Spasic Boskovic O, Korolchuk S, Jauniaux E, et al. Oxidative stress, gene expression, and protein changes induced in the human placenta during labor. Am J Pathol. 2007;171:1168-79 pubmed
Carroll P, Kenerson H, Yeung R, Lagunoff M. Latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells activates hypoxia-induced factors. J Virol. 2006;80:10802-12 pubmed
Nevo O, Soleymanlou N, Wu Y, Xu J, Kingdom J, Many A, et al. Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1. Am J Physiol Regul Integr Comp Physiol. 2006;291:R1085-93 pubmed
product information
CatalogNumber :
ab9540
ItemName :
Anti-VEGF Receptor 1 antibody [Flt-1/EWC]
Product Type :
Antibody
Host Species :
Mouse
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
Flt-1/EWC
Size :
100 µg
SpeciesSummary :
Dog, Hu, Ms
Purity :
Protein G purified
Application Summary :
ELISA, Flow Cyt, ICC/IF, IHC-P, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK