This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-Tet2 antibody
catalog :
ab94580
quantity :
100 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, western blot knockout validation
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; fig 7a
Ma S, Wan X, Deng Z, Shi L, Hao C, Zhou Z, et al. Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs. J Exp Med. 2017;214:1471-1491 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 7d
  • western blot; human; loading ...; fig 1f
Bao Y, Bai M, Zhu H, Yuan Y, Wang Y, Zhang Y, et al. DNA demethylase Tet2 suppresses cisplatin-induced acute kidney injury. Cell Death Discov. 2021;7:167 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 2a
Ostriker A, Xie Y, Chakraborty R, Sizer A, Bai Y, Ding M, et al. TET2 Protects Against Vascular Smooth Muscle Cell Apoptosis and Intimal Thickening in Transplant Vasculopathy. Circulation. 2021;144:455-470 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 1c
  • western blot; mouse; loading ...; fig 1a
  • immunohistochemistry; human; loading ...; fig 1c
  • western blot; human; loading ...; fig 1a
Yang R, Yu T, Kou X, Gao X, Chen C, Liu D, et al. Tet1 and Tet2 maintain mesenchymal stem cell homeostasis via demethylation of the P2rX7 promoter. Nat Commun. 2018;9:2143 pubmed publisher
  • western blot; mouse; fig 3c
Yosefzon Y, David C, Tsukerman A, Pnueli L, Qiao S, Boehm U, et al. An epigenetic switch repressing Tet1 in gonadotropes activates the reproductive axis. Proc Natl Acad Sci U S A. 2017;114:10131-10136 pubmed publisher
  • western blot; mouse; loading ...; fig s5d
Choi J, Clement K, Huebner A, Webster J, Rose C, Brumbaugh J, et al. DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells. Cell Stem Cell. 2017;20:706-719.e7 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig st1
Yip P, Carrillo Jimenez A, King P, Vilalta A, Nomura K, Chau C, et al. Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration. Sci Rep. 2017;7:41689 pubmed publisher
Lv J, Liu Y, Mo S, Zhou Y, Chen F, Cheng F, et al. Gasdermin E mediates resistance of pancreatic adenocarcinoma to enzymatic digestion through a YBX1-mucin pathway. Nat Cell Biol. 2022;24:364-372 pubmed publisher
Reimer M, Pulakanti K, Shi L, Abel A, Liang M, Malarkannan S, et al. Deletion of Tet proteins results in quantitative disparities during ESC differentiation partially attributable to alterations in gene expression. BMC Dev Biol. 2019;19:16 pubmed publisher
Shenoy N, Bhagat T, Cheville J, Lohse C, Bhattacharyya S, Tischer A, et al. Ascorbic acid-induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma. J Clin Invest. 2019;130:1612-1625 pubmed publisher
Zhong X, Wang Q, Li J, Zhang Y, An X, Hou J. Ten-Eleven Translocation-2 (Tet2) Is Involved in Myogenic Differentiation of Skeletal Myoblast Cells in Vitro. Sci Rep. 2017;7:43539 pubmed publisher
Nair V, Song M, Ko M, Oh K. DNA Demethylation of the Foxp3 Enhancer Is Maintained through Modulation of Ten-Eleven-Translocation and DNA Methyltransferases. Mol Cells. 2016;39:888-897 pubmed publisher
Galoian K, Luo S, Qureshi A, Patel P, Price R, Morse A, et al. Effect of cytostatic proline rich polypeptide-1 on tumor suppressors of inflammation pathway signaling in chondrosarcoma. Mol Clin Oncol. 2016;5:618-624 pubmed
product information
CatalogNumber :
ab94580
ItemName :
Anti-Tet2 antibody
Category :
Antibody
Host :
Rabbit
Clonality :
Polyclonal
Conjugate :
Unconjugated
Size :
100 µg
SpeciesSummary :
Hu, Mmst, Ms
Application Summary :
ICC/IF, IHC-P, IP, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK