| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; loading ...; fig 1f, 2e
| Chuang H, Chen M, Chen Y, Yang H, Ciou Y, Hsueh C, et al. BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus. Theranostics. 2021;11:9953-9966 pubmed publisher |
- western blot; rhesus macaque; loading ...; fig 10d
| Sil S, Singh S, Chemparathy D, Chivero E, Gordon L, Buch S. Astrocytes & Astrocyte derived Extracellular Vesicles in Morphine Induced Amyloidopathy: Implications for Cognitive Deficits in Opiate Abusers. Aging Dis. 2021;12:1389-1408 pubmed publisher |
- western blot; human; 1:1000; fig 1b
| Cai M, Chai S, Xiong T, Wei J, Mao W, Zhu Y, et al. Aberrant Expression of Circulating MicroRNA Leads to the Dysregulation of Alpha-Synuclein and Other Pathogenic Genes in Parkinson's Disease. Front Cell Dev Biol. 2021;9:695007 pubmed publisher |
- western blot; rat; loading ...; fig 2g
| Song L, Tian X, Schekman R. Extracellular vesicles from neurons promote neural induction of stem cells through cyclin D1. J Cell Biol. 2021;220: pubmed publisher |
- western blot; human; loading ...; fig 6h
| Zhang K, Liu D, Zhao J, Shi S, He X, Da P, et al. Nuclear exosome HMGB3 secreted by nasopharyngeal carcinoma cells promotes tumour metastasis by inducing angiogenesis. Cell Death Dis. 2021;12:554 pubmed publisher |
- western blot; human; 1:200; loading ...; fig 2b
| Ganig N, Baenke F, Thepkaysone M, Lin K, Rao V, Wong F, et al. Proteomic Analyses of Fibroblast- and Serum-Derived Exosomes Identify QSOX1 as a Marker for Non-invasive Detection of Colorectal Cancer. Cancers (Basel). 2021;13: pubmed publisher |
- western blot; human; 1:1000; fig 1e
| Zhang Z, Zou X, Zhang R, Xie Y, Feng Z, Li F, et al. Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke. Aging (Albany NY). 2021;13:3060-3079 pubmed publisher |
- western blot; human; fig s4b
- western blot; mouse; loading ...; fig s2d
| Kumar A, Sundaram K, Mu J, Dryden G, Sriwastva M, Lei C, et al. High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance. Nat Commun. 2021;12:213 pubmed publisher |
- immunohistochemistry; mouse; 1:500; loading ...; fig 11h
| Pasquettaz R, Kolotuev I, Rohrbach A, Gouelle C, Pellerin L, Langlet F. Peculiar protrusions along tanycyte processes face diverse neural and nonneural cell types in the hypothalamic parenchyma. J Comp Neurol. 2021;529:553-575 pubmed publisher |
- western blot; human; loading ...; fig 1a
| Cordonnier M, Nardin C, Chanteloup G, Derangère V, Algros M, Arnould L, et al. Tracking the evolution of circulating exosomal-PD-L1 to monitor melanoma patients. J Extracell Vesicles. 2020;9:1710899 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig s4c
| Medeiros B, Goodale D, Postenka C, Lowes L, Kiser P, Hearn S, et al. Triple-Negative Primary Breast Tumors Induce Supportive Premetastatic Changes in the Extracellular Matrix and Soluble Components of the Lung Microenvironment. Cancers (Basel). 2020;12: pubmed publisher |
- western blot; human; loading ...; fig 1b
| Wan Z, Zhao L, Lu F, Gao X, Dong Y, Zhao Y, et al. Mononuclear phagocyte system blockade improves therapeutic exosome delivery to the myocardium. Theranostics. 2020;10:218-230 pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 1e
| Yu T, Zhao C, Hou S, Zhou W, Wang B, Chen Y. Exosomes secreted from miRNA-29b-modified mesenchymal stem cells repaired spinal cord injury in rats. Braz J Med Biol Res. 2019;52:e8735 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 1i
| Yang X, Yang J, Lei P, Wen T. LncRNA MALAT1 shuttled by bone marrow-derived mesenchymal stem cells-secreted exosomes alleviates osteoporosis through mediating microRNA-34c/SATB2 axis. Aging (Albany NY). 2019;11:8777-8791 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:2000; loading ...; fig 2h
| Ramachandran P, Dobie R, Wilson Kanamori J, Dora E, Henderson B, Luu N, et al. Resolving the fibrotic niche of human liver cirrhosis at single-cell level. Nature. 2019;575:512-518 pubmed publisher |
- western blot; human; loading ...; fig 1c
| Ortega F, Roefs M, De Miguel Pérez D, Kooijmans S, de Jong O, Sluijter J, et al. Interfering with endolysosomal trafficking enhances release of bioactive exosomes. Nanomedicine. 2019;:102014 pubmed publisher |
- western blot; human; loading ...; fig s5e
| Murillo O, Thistlethwaite W, Rozowsky J, Subramanian S, Lucero R, Shah N, et al. exRNA Atlas Analysis Reveals Distinct Extracellular RNA Cargo Types and Their Carriers Present across Human Biofluids. Cell. 2019;177:463-477.e15 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 7a
- western blot; human; loading ...; fig 1b, s4a, 3d, 4h
| Jeppesen D, Fenix A, Franklin J, Higginbotham J, Zhang Q, Zimmerman L, et al. Reassessment of Exosome Composition. Cell. 2019;177:428-445.e18 pubmed publisher |
- western blot; human; loading ...; fig s6g
| Huang F, Feng F. A Tumor-Agnostic NTRK (TRK) Inhibitor. Cell. 2019;177:8 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1a
- immunocytochemistry; human; 1:100; loading ...; fig 1a
- western blot; human; loading ...; fig 1b
| Liu J, Zhu G, Jia N, Wang W, Wang Y, Yin M, et al. CD9 regulates keratinocyte migration by negatively modulating the sheddase activity of ADAM17. Int J Biol Sci. 2019;15:493-506 pubmed publisher |
- western blot; mouse; 1:2000; loading ...; fig 3c
| Erwig M, Patzig J, Steyer A, Dibaj P, Heilmann M, Heilmann I, et al. Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin. elife. 2019;8: pubmed publisher |
- western blot; mouse; loading ...; fig s1
| Silverman J, Christy D, Shyu C, Moon K, Fernando S, Gidden Z, et al. CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1)G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1. J Biol Chem. 2019;294:3744-3759 pubmed publisher |
- western blot; human; 1:150; loading ...; fig 2c
| Tiedemann K, Sadvakassova G, Mikolajewicz N, Juhas M, Sabirova Z, Tabariès S, et al. Exosomal Release of L-Plastin by Breast Cancer Cells Facilitates Metastatic Bone Osteolysis. Transl Oncol. 2019;12:462-474 pubmed publisher |
- western blot; human; loading ...; fig 1c
| Messenger S, Woo S, Sun Z, Martin T. A Ca2+-stimulated exosome release pathway in cancer cells is regulated by Munc13-4. J Cell Biol. 2018;217:2877-2890 pubmed publisher |
- western blot; human; 1:500; loading ...; fig 1d
| Li H, Liao Y, Gao L, Zhuang T, Huang Z, Zhu H, et al. Coronary Serum Exosomes Derived from Patients with Myocardial Ischemia Regulate Angiogenesis through the miR-939-mediated Nitric Oxide Signaling Pathway. Theranostics. 2018;8:2079-2093 pubmed publisher |
- western blot; mouse; 1:250; fig 5b
| Saha S, Aranda E, Hayakawa Y, Bhanja P, Atay S, Brodin N, et al. Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury. Nat Commun. 2016;7:13096 pubmed publisher |
- western blot; human; fig 3
| Edgar J, Manna P, Nishimura S, Banting G, Robinson M. Tetherin is an exosomal tether. elife. 2016;5: pubmed publisher |
- western blot; mouse; 1:1000; fig 8c
| Coenen Stass A, Betts C, Lee Y, Mäger I, Turunen M, El Andaloussi S, et al. Selective release of muscle-specific, extracellular microRNAs during myogenic differentiation. Hum Mol Genet. 2016;25:3960-3974 pubmed publisher |
- western blot; human; 1:1000; fig 3b
| Pinet S, Bessette B, Vedrenne N, Lacroix A, Richard L, Jauberteau M, et al. TrkB-containing exosomes promote the transfer of glioblastoma aggressiveness to YKL-40-inactivated glioblastoma cells. Oncotarget. 2016;7:50349-50364 pubmed publisher |
- western blot; human; 1:1000; fig 1
| Sun Y, Zheng W, Guo Z, Ju Q, Zhu L, Gao J, et al. A novel TP53 pathway influences the HGS-mediated exosome formation in colorectal cancer. Sci Rep. 2016;6:28083 pubmed publisher |
- western blot; human; 1:2500; fig 2b
| Kooijmans S, Fliervoet L, van der Meel R, Fens M, Heijnen H, van Bergen En Henegouwen P, et al. PEGylated and targeted extracellular vesicles display enhanced cell specificity and circulation time. J Control Release. 2016;224:77-85 pubmed publisher |
- western blot; human; fig 2
| Shimoda A, Ueda K, Nishiumi S, Murata Kamiya N, Mukai S, Sawada S, et al. Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA. Sci Rep. 2016;6:18346 pubmed publisher |
- other; human; 1:300; loading ...; fig s1c
- other; mouse; 1:300; loading ...; fig s1c
| Melo S, Luecke L, Kahlert C, Fernandez A, Gammon S, Kaye J, et al. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature. 2015;523:177-82 pubmed publisher |
| Deng Y, Tong J, Shi W, Tian Z, Yu B, Tang J. Thromboangiitis obliterans plasma-derived exosomal miR-223-5p inhibits cell viability and promotes cell apoptosis of human vascular smooth muscle cells by targeting VCAM1. Ann Med. 2021;53:1129-1141 pubmed publisher |
| Sha S, Shen X, Cao Y, Qu L. Mesenchymal stem cells-derived extracellular vesicles ameliorate Alzheimer's disease in rat models via the microRNA-29c-3p/BACE1 axis and the Wnt/β-catenin pathway. Aging (Albany NY). 2021;13:15285-15306 pubmed publisher |
| Mao C, Li D, Zhou E, Gao E, Zhang T, Sun S, et al. Extracellular vesicles from anoxia preconditioned mesenchymal stem cells alleviate myocardial ischemia/reperfusion injury. Aging (Albany NY). 2021;13:6156-6170 pubmed publisher |
| Ou H, Teng H, Qin Y, Luo X, Yang P, Zhang W, et al. Extracellular vesicles derived from microRNA-150-5p-overexpressing mesenchymal stem cells protect rat hearts against ischemia/reperfusion. Aging (Albany NY). 2020;12:12669-12683 pubmed publisher |
| Yao Z, Jia C, Tai Y, Liang H, Zhong Z, Xiong Z, et al. Serum exosomal long noncoding RNAs lnc-FAM72D-3 and lnc-EPC1-4 as diagnostic biomarkers for hepatocellular carcinoma. Aging (Albany NY). 2020;12:11843-11863 pubmed publisher |
| Xiong Y, Chen L, Yu T, Yan C, Zhou W, Cao F, et al. Inhibition of circulating exosomal microRNA-15a-3p accelerates diabetic wound repair. Aging (Albany NY). 2020;12:8968-8986 pubmed publisher |
| Deng Q, Fang Q, Xie B, Sun H, Bao Y, Zhou S. Exosomal long non-coding RNA MSTRG.292666.16 is associated with osimertinib (AZD9291) resistance in non-small cell lung cancer. Aging (Albany NY). 2020;12:8001-8015 pubmed publisher |
| de Jong O, Murphy D, Mäger I, Willms E, Garcia Guerra A, Gitz Francois J, et al. A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA. Nat Commun. 2020;11:1113 pubmed publisher |
| Gao C, Gong Z, Wang D, Huang J, Qian Y, Nie M, et al. Hematoma-derived exosomes of chronic subdural hematoma promote abnormal angiogenesis and inhibit hematoma absorption through miR-144-5p. Aging (Albany NY). 2019;11:12147-12164 pubmed publisher |
| Luo Y, Huang L, Luo W, Ye S, Hu Q. Genomic analysis of lncRNA and mRNA profiles in circulating exosomes of patients with rheumatic heart disease. Biol Open. 2019;8: pubmed publisher |
| Tian S, Wu Q, Zhou B, Choi M, Ding B, Yang W, et al. Proteomic Analysis Identifies Membrane Proteins Dependent on the ER Membrane Protein Complex. Cell Rep. 2019;28:2517-2526.e5 pubmed publisher |
| Kim D, Kim H, Choi Y, Kim S, Lee J, Sung K, et al. Exosomal PD-L1 promotes tumor growth through immune escape in non-small cell lung cancer. Exp Mol Med. 2019;51:94 pubmed publisher |
| Wang J, Li X, Wu X, Wang Z, Zhang C, Cao G, et al. Expression Profiling of Exosomal miRNAs Derived from the Peripheral Blood of Kidney Recipients with DGF Using High-Throughput Sequencing. Biomed Res Int. 2019;2019:1759697 pubmed publisher |
| Satoh Y, Takei N, Kawamura S, Takahashi N, Kotani T, Kimura A. A novel testis-specific long noncoding RNA, Tesra, activates the Prss42/Tessp-2 gene during mouse spermatogenesis†. Biol Reprod. 2019;100:833-848 pubmed publisher |
| Lee C, Im E, Moon P, Baek M. Discovery of a diagnostic biomarker for colon cancer through proteomic profiling of small extracellular vesicles. BMC Cancer. 2018;18:1058 pubmed publisher |
| Hardin H, Helein H, Meyer K, Robertson S, Zhang R, Zhong W, et al. Thyroid cancer stem-like cell exosomes: regulation of EMT via transfer of lncRNAs. Lab Invest. 2018;98:1133-1142 pubmed publisher |
| Degosserie J, Heymans C, Spourquet C, Halbout M, D Auria L, Van Der Smissen P, et al. Extracellular vesicles from endothelial progenitor cells promote thyroid follicle formation. J Extracell Vesicles. 2018;7:1487250 pubmed publisher |
| Lv C, Yu W, Wang Y, Yi D, Zeng M, Xiao H. MiR-21 in extracellular vesicles contributes to the growth of fertilized eggs and embryo development in mice. Biosci Rep. 2018;38: pubmed publisher |
| Hill D, Lim H, Kim Y, Ho W, Foong Y, Nelson V, et al. Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue. Proc Natl Acad Sci U S A. 2018;115:E5096-E5105 pubmed publisher |
| Schiller L, Lemus Diaz N, Rinaldi Ferreira R, Böker K, Gruber J. Enhanced Production of Exosome-Associated AAV by Overexpression of the Tetraspanin CD9. Mol Ther Methods Clin Dev. 2018;9:278-287 pubmed publisher |
| Abdulrahman B, Abdelaziz D, Schatzl H. Autophagy regulates exosomal release of prions in neuronal cells. J Biol Chem. 2018;293:8956-8968 pubmed publisher |
| Gao Y, Ge W. The histone methyltransferase DOT1L inhibits osteoclastogenesis and protects against osteoporosis. Cell Death Dis. 2018;9:33 pubmed publisher |
| Thomou T, Mori M, Dreyfuss J, Konishi M, Sakaguchi M, Wolfrum C, et al. Adipose-derived circulating miRNAs regulate gene expression in other tissues. Nature. 2017;542:450-455 pubmed publisher |
