| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; human; loading ...; fig 2j
| Wu T, Wang W, Shi G, Hao M, Wang Y, Yao M, et al. Targeting HIC1/TGF-β axis-shaped prostate cancer microenvironment restrains its progression. Cell Death Dis. 2022;13:624 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig 8b
| Mancinelli R, Ceci L, Kennedy L, Francis H, Meadows V, Chen L, et al. The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling. Cells. 2022;11: pubmed publisher |
- immunohistochemistry; human; loading ...; fig 2a
- western blot; human; loading ...; fig 2e
- western blot; mouse; loading ...; fig 4h
| Gu P, Wang D, Zhang J, Wang X, Chen Z, Gu L, et al. Protective function of interleukin-22 in pulmonary fibrosis. Clin Transl Med. 2021;11:e509 pubmed publisher |
- western blot; mouse; 1:400; loading ...; fig 1b
| Escasany E, Lanzón B, García Carrasco A, Izquierdo Lahuerta A, Torres L, Corrales P, et al. Transforming growth factor β3 deficiency promotes defective lipid metabolism and fibrosis in murine kidney. Dis Model Mech. 2021;14: pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 2d
| Cai C, Zeng D, Gao Q, Ma L, Zeng B, Zhou Y, et al. Decreased ferroportin in hepatocytes promotes macrophages polarize towards an M2-like phenotype and liver fibrosis. Sci Rep. 2021;11:13386 pubmed publisher |
- western blot; mouse; 0.25 ug/ml; loading ...; fig 4b, 5b
| Wu X, Shu L, Zhang Z, Li J, Zong J, Cheong L, et al. Adipocyte Fatty Acid Binding Protein Promotes the Onset and Progression of Liver Fibrosis via Mediating the Crosstalk between Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells. Adv Sci (Weinh). 2021;8:e2003721 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 6b
| Zhang Z, Lin M, Wang J, Yang F, Yang P, Liu Y, et al. Calycosin inhibits breast cancer cell migration and invasion by suppressing EMT via BATF/TGF-β1. Aging (Albany NY). 2021;13:16009-16023 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 8f
| Li J, Sun Z, Luo G, Wang S, Cui H, Yao Z, et al. Quercetin Attenuates Trauma-Induced Heterotopic Ossification by Tuning Immune Cell Infiltration and Related Inflammatory Insult. Front Immunol. 2021;12:649285 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 14g
| Hsieh Y, Lee K, Lei H, Lan K, Huo T, Lin Y, et al. (Pro)renin Receptor Knockdown Attenuates Liver Fibrosis Through Inactivation of ERK/TGF-β1/SMAD3 Pathway. Cell Mol Gastroenterol Hepatol. 2021;12:813-838 pubmed publisher |
- western blot; mouse; loading ...; fig 2f
| Ye S, Su L, Shan P, Ye B, Wu S, Liang G, et al. LCZ696 Attenuated Doxorubicin-Induced Chronic Cardiomyopathy Through the TLR2-MyD88 Complex Formation. Front Cell Dev Biol. 2021;9:654051 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3g
| Wang Y, Xu Z, Wang X, Zheng J, Peng L, Zhou Y, et al. Extracellular-vesicle containing miRNA-503-5p released by macrophages contributes to atherosclerosis. Aging (Albany NY). 2021;13:12239-12257 pubmed publisher |
- western blot; mouse; 1:2000; loading ...; fig 3a
| Sharma N, Hans C. Interleukin 12p40 Deficiency Promotes Abdominal Aortic Aneurysm by Activating CCN2/MMP2 Pathways. J Am Heart Assoc. 2021;10:e017633 pubmed publisher |
- western blot; rat; 1:3000; loading ...; fig 6a
| Chen Y, Chen H, Fan H, Tung Y, Kuo C, Tu M, et al. Anti-Inflammatory, Antioxidant, and Antifibrotic Effects of Kefir Peptides on Salt-Induced Renal Vascular Damage and Dysfunction in Aged Stroke-Prone Spontaneously Hypertensive Rats. Antioxidants (Basel). 2020;9: pubmed publisher |
- western blot; mouse; loading ...; fig 6d
| Guo X, Kolpakov M, Hooshdaran B, Schappell W, Wang T, Eguchi S, et al. Cardiac Expression of Factor X Mediates Cardiac Hypertrophy and Fibrosis in Pressure Overload. JACC Basic Transl Sci. 2020;5:69-83 pubmed publisher |
- other; mouse; 1:100; loading ...; fig 1c
| Voisin A, Damon Soubeyrand C, Bravard S, Saez F, Drevet J, Guiton R. Differential expression and localisation of TGF-β isoforms and receptors in the murine epididymis. Sci Rep. 2020;10:995 pubmed publisher |
- western blot; human; 1:250; loading ...; fig 4b
| Ye D, Zhu J, Zhao Q, Ma W, Xiao Y, Xu G, et al. LMP1 Up-regulates Calreticulin to Induce Epithelial-mesenchymal Transition via TGF-β/Smad3/NRP1 Pathway in Nasopharyngeal Carcinoma Cells. J Cancer. 2020;11:1257-1269 pubmed publisher |
- immunohistochemistry; human; loading ...; fig 1a
| Zhou S, da Silva S, Siegel P, Philip A. CD109 acts as a gatekeeper of the epithelial trait by suppressing epithelial to mesenchymal transition in squamous cell carcinoma cells in vitro. Sci Rep. 2019;9:16317 pubmed publisher |
- immunohistochemistry; mouse; 1:100; loading ...; fig 2
| Wang X, Zhao L, Ajay A, Jiao B, Zhang X, Wang C, et al. QiDiTangShen Granules Activate Renal Nutrient-Sensing Associated Autophagy in db/db Mice. Front Physiol. 2019;10:1224 pubmed publisher |
- western blot; human; 4 ug/ml; loading ...; fig 3d
| Shen J, Xing W, Liu R, Zhang Y, Xie C, Gong F. MiR-32-5p influences high glucose-induced cardiac fibroblast proliferation and phenotypic alteration by inhibiting DUSP1. BMC Mol Biol. 2019;20:21 pubmed publisher |
- immunohistochemistry; mouse; 1:50; loading ...; fig 4f
| Wang H, Shen L, Sun X, Liu F, Feng W, Jiang C, et al. Adipose group 1 innate lymphoid cells promote adipose tissue fibrosis and diabetes in obesity. Nat Commun. 2019;10:3254 pubmed publisher |
- western blot; mouse; 1:500; loading ...; fig 7d
| HASAN A, von Websky K, Reichetzeder C, Tsuprykov O, Gaballa M, Guo J, et al. Mechanisms of GLP-1 receptor-independent renoprotective effects of the dipeptidyl peptidase type 4 inhibitor linagliptin in GLP-1 receptor knockout mice with 5/6 nephrectomy. Kidney Int. 2019;95:1373-1388 pubmed publisher |
- western blot; mouse; loading ...; fig 4c
| Yin J, Wang Y, Chang J, Li B, Zhang J, Liu Y, et al. Apelin inhibited epithelial-mesenchymal transition of podocytes in diabetic mice through downregulating immunoproteasome subunits β5i. Cell Death Dis. 2018;9:1031 pubmed publisher |
- western blot; mouse; fig 6c
| Wang Q, Yu Y, Zhang P, Chen Y, Li C, Chen J, et al. The crucial role of activin A/ALK4 pathway in the pathogenesis of Ang-II-induced atrial fibrosis and vulnerability to atrial fibrillation. Basic Res Cardiol. 2017;112:47 pubmed publisher |
- immunohistochemistry; rat; 1:400; loading ...; fig 11c
| Manzanares M, Usui A, Campbell D, Dumur C, Maldonado G, Fausther M, et al. Transforming Growth Factors α and β Are Essential for Modeling Cholangiocarcinoma Desmoplasia and Progression in a Three-Dimensional Organotypic Culture Model. Am J Pathol. 2017;187:1068-1092 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2i
| Oller J, Méndez Barbero N, Ruiz E, Villahoz S, Renard M, Canelas L, et al. Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome. Nat Med. 2017;23:200-212 pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 4c
| Wang Y, Han G, Guo B, Huang J. Hyaluronan oligosaccharides promote diabetic wound healing by increasing angiogenesis. Pharmacol Rep. 2016;68:1126-1132 pubmed publisher |
| Kharin L, Bychkov I, Karnaukhov N, Voloshin M, Fazliyeva R, Deneka A, et al. Prognostic role and biologic features of Musashi-2 expression in colon polyps and during colorectal cancer progression. PLoS ONE. 2021;16:e0252132 pubmed publisher |
| Xiao K, Yang L, Xie W, Gao X, Huang R, Xie M. Bcl-xL mutant promotes cartilage differentiation of BMSCs by upregulating TGF-β/BMP expression levels. Exp Ther Med. 2021;22:736 pubmed publisher |
| Lin K, Luo W, Yan J, Shen S, Shen Q, Wang J, et al. TLR2 regulates angiotensin II-induced vascular remodeling and EndMT through NF-κB signaling. Aging (Albany NY). 2020;13:2553-2574 pubmed publisher |
| Du J, Yin G, Hu Y, Shi S, Jiang J, Song X, et al. Coicis semen protects against focal cerebral ischemia-reperfusion injury by inhibiting oxidative stress and promoting angiogenesis via the TGFβ/ALK1/Smad1/5 signaling pathway. Aging (Albany NY). 2020;13:877-893 pubmed publisher |
| Jiang D, Guo B, Lin F, Lin S, Tao K. miR-205 inhibits the development of hypertrophic scars by targeting THBS1. Aging (Albany NY). 2020;12:22046-22058 pubmed publisher |
| Yang C, Chen X, Li Z, Wu H, Jing K, Huang X, et al. SMAD3 promotes autophagy dysregulation by triggering lysosome depletion in tubular epithelial cells in diabetic nephropathy. Autophagy. 2020;:1-20 pubmed publisher |
| Wu J, Jia A, Tan Y, Xu H, Tian J, Wang Y, et al. Effect of Alpina oxyphylla extract on streptozotocin-induced kidney injure via regulating TGF-β1 and MyD88. BMC Complement Med Ther. 2020;20:217 pubmed publisher |
| Chen Y, Liu F, Han F, Lv L, Tang C, Xie Z, et al. Omentin-1 is associated with atrial fibrillation in patients with cardiac valve disease. BMC Cardiovasc Disord. 2020;20:214 pubmed publisher |
| Chen J, Yi X, Gu P, Gao S. The role of KDR in intrauterine adhesions may involve the TGF-β1/Smads signaling pathway. Braz J Med Biol Res. 2019;52:e8324 pubmed publisher |
| Gu Y, Wang W, Wang X, Xie H, Ye X, Shu P. Integrated network analysis identifies hsa-miR-4756-3p as a regulator of FOXM1 in Triple Negative Breast Cancer. Sci Rep. 2019;9:13830 pubmed publisher |
| Meng X, McGraw C, Wang W, Jing J, Yeh S, Wang L, et al. Neurexophilin4 is a selectively expressed α-neurexin ligand that modulates specific cerebellar synapses and motor functions. elife. 2019;8: pubmed publisher |
| Ottaiano A, Scala S, Normanno N, Napolitano M, Capozzi M, Rachiglio A, et al. Cetuximab, irinotecan and fluorouracile in fiRst-line treatment of immunologically-selected advanced colorectal cancer patients: the CIFRA study protocol. BMC Cancer. 2019;19:899 pubmed publisher |
| Zhang X, Du K, Lou Z, Ding K, Zhang F, Zhu J, et al. The CtBP1-HDAC1/2-IRF1 transcriptional complex represses the expression of the long noncoding RNA GAS5 in human osteosarcoma cells. Int J Biol Sci. 2019;15:1460-1471 pubmed publisher |
| Yang J, Zhang Y, Xu X, Li J, Yuan F, Bo S, et al. Transforming growth factor-β is involved in maintaining oocyte meiotic arrest by promoting natriuretic peptide type C expression in mouse granulosa cells. Cell Death Dis. 2019;10:558 pubmed publisher |
| Li H, Zhu R, Zhao R, Qian L, Jiang L. Role of TGF-Beta1/SMAD2/3 Pathway in Retinal Outer Deep Vascular Plexus and Photoreceptor Damage in Rat 50/10 Oxygen-Induced Retinopathy. Biomed Res Int. 2019;2019:4072319 pubmed publisher |
| Liu J, Jiang W, Zhao K, Wang H, Zhou T, Bai W, et al. Tumoral EHF predicts the efficacy of anti-PD1 therapy in pancreatic ductal adenocarcinoma. J Exp Med. 2019;216:656-673 pubmed publisher |
| Li P, He R, Shi S, Li R, Wang Q, Rao G, et al. Modulation of miR-10a-mediated TGF-β1/Smads signaling affects atrial fibrillation-induced cardiac fibrosis and cardiac fibroblast proliferation. Biosci Rep. 2019;39: pubmed publisher |
| Yao L, Li J, Li L, Li X, Zhang R, Zhang Y, et al. Coreopsis tinctoria Nutt ameliorates high glucose-induced renal fibrosis and inflammation via the TGF-β1/SMADS/AMPK/NF-κB pathways. BMC Complement Altern Med. 2019;19:14 pubmed publisher |
| Li W, Wu X, She W. LncRNA POU3F3 promotes cancer cell migration and invasion in nasopharyngeal carcinoma by up-regulating TGF-β1. Biosci Rep. 2019;39: pubmed publisher |
| Yao J, Zhang X, Li J, Zhao D, Gao B, Zhou H, et al. Silencing TRIP13 inhibits cell growth and metastasis of hepatocellular carcinoma by activating of TGF-β1/smad3. Cancer Cell Int. 2018;18:208 pubmed publisher |
| Ebrahim N, Ahmed I, Hussien N, Dessouky A, Farid A, Elshazly A, et al. Mesenchymal Stem Cell-Derived Exosomes Ameliorated Diabetic Nephropathy by Autophagy Induction through the mTOR Signaling Pathway. Cells. 2018;7: pubmed publisher |
| Zheng C, Lin J, Lin Z, Lin W, Thapa S, Lin Y, et al. Sodium Houttuyfonate Alleviates Post-infarct Remodeling in Rats via AMP-Activated Protein Kinase Pathway. Front Pharmacol. 2018;9:1092 pubmed publisher |
| Zheng Z, Gao Y. Down-regulation of lncRNA snaR is correlated with postoperative distant recurrence of HPV-negative cervical squamous cell carcinoma. Biosci Rep. 2018;38: pubmed publisher |
| Paakkola T, Salokas K, Miinalainen I, Lehtonen S, Manninen A, Kaakinen M, et al. Biallelic mutations in human NHLRC2 enhance myofibroblast differentiation in FINCA disease. Hum Mol Genet. 2018;27:4288-4302 pubmed publisher |
| Chen Q, Zhao T, Xie X, Yu D, Wu L, Yu W, et al. MicroRNA-663 regulates the proliferation of fibroblasts in hypertrophic scars via transforming growth factor-β1. Exp Ther Med. 2018;16:1311-1317 pubmed publisher |
| Wang X, Song Q. Mst1 regulates post-infarction cardiac injury through the JNK-Drp1-mitochondrial fission pathway. Cell Mol Biol Lett. 2018;23:21 pubmed publisher |
| Wang X, Wang G, Zhang L, Cong J, Hou J, Liu C. LncRNA PVT1 promotes the growth of HPV positive and negative cervical squamous cell carcinoma by inhibiting TGF-β1. Cancer Cell Int. 2018;18:70 pubmed publisher |
| Su H, Zhang Z, Liu Z, Peng B, Kong C, Wang H, et al. Mycobacterium tuberculosis PPE60 antigen drives Th1/Th17 responses via Toll-like receptor 2-dependent maturation of dendritic cells. J Biol Chem. 2018;293:10287-10302 pubmed publisher |
| Jiang L, Han X, Wang J, Wang C, Sun X, Xie J, et al. SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-β signaling. J Exp Med. 2018;215:1337-1347 pubmed publisher |
| Wu X, Zhi F, Lun W, Deng Q, Zhang W. Baicalin inhibits PDGF-BB-induced hepatic stellate cell proliferation, apoptosis, invasion, migration and activation via the miR-3595/ACSL4 axis. Int J Mol Med. 2018;41:1992-2002 pubmed publisher |
| Zhang H, Yang Y, Wang Y, Wang B, Li R. Renal-protective effect of thalidomide in streptozotocin-induced diabetic rats through anti-inflammatory pathway. Drug Des Devel Ther. 2018;12:89-98 pubmed publisher |
| Saito Y, Chikenji T, Ozasa Y, Fujimiya M, Yamashita T, Gingery A, et al. PDGFR Signaling Mediates Hyperproliferation and Fibrotic Responses of Subsynovial Connective Tissue Cells in Idiopathic Carpal Tunnel Syndrome. Sci Rep. 2017;7:16192 pubmed publisher |
| Livingston M, Ding H, Huang S, Hill J, Yin X, Dong Z. Persistent activation of autophagy in kidney tubular cells promotes renal interstitial fibrosis during unilateral ureteral obstruction. Autophagy. 2016;12:976-98 pubmed publisher |
| Zhang G, Yang G, Deng Y, Zhao X, Yang Y, Rao J, et al. Ameliorative effects of Xue-Fu-Zhu-Yu decoction, Tian-Ma-Gou-Teng-Yin and Wen-Dan decoction on myocardial fibrosis in a hypertensive rat mode. BMC Complement Altern Med. 2016;16:56 pubmed publisher |
