| Published Application/Species/Sample/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; mouse; loading ...; fig 5b
- western blot; human; 1:100; loading ...; fig 4c
| Leach D, Mohr A, Giotis E, Cil E, Isac A, Yates L, et al. The antiandrogen enzalutamide downregulates TMPRSS2 and reduces cellular entry of SARS-CoV-2 in human lung cells. Nat Commun. 2021;12:4068 pubmed publisher |
- immunohistochemistry; human; fig 2g
| Camell C, Yousefzadeh M, Zhu Y, Langhi Prata L, Huggins M, Pierson M, et al. Senolytics reduce coronavirus-related mortality in old mice. Science. 2021;: pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:250; loading ...; fig 3b, s4m
- immunocytochemistry; human; 1:250; loading ...; fig s5g
- western blot; human; 1:1000; loading ...; fig s2b
| Li F, Han M, Dai P, Xu W, He J, Tao X, et al. Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide. Nat Commun. 2021;12:866 pubmed publisher |
- immunohistochemistry; mouse; loading ...; fig 2c
| Sagawa T, Tsujikawa T, Honda A, Miyasaka N, Tanaka M, Kida T, et al. Exposure to particulate matter upregulates ACE2 and TMPRSS2 expression in the murine lung. Environ Res. 2021;195:110722 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 1b
- western blot; human; fig 5a
| Earnest J, Hantak M, Li K, McCray P, Perlman S, Gallagher T. The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases. PLoS Pathog. 2017;13:e1006546 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2b
| Dutta A, Le Magnen C, Mitrofanova A, Ouyang X, Califano A, Abate Shen C. Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation. Science. 2016;352:1576-80 pubmed publisher |
| Wu C, Yang Y, Lin Y, Shu L, Cheng Y, Liu H, et al. The anti-SARS-CoV-2 effect and mechanism of Chiehyuan herbal oral protection solution. Heliyon. 2023;9:e17701 pubmed publisher |
| Wang L, Wang S, Wu L, Li W, Bray W, Clark A, et al. PCIF1-mediated deposition of 5'-cap N6,2'-O-dimethyladenosine in ACE2 and TMPRSS2 mRNA regulates susceptibility to SARS-CoV-2 infection. Proc Natl Acad Sci U S A. 2023;120:e2210361120 pubmed publisher |
| Bhullar K, Nael M, Elokely K, Drews S, Wu J. Structurally Modified Bioactive Peptide Inhibits SARS-CoV-2 Lentiviral Particles Expression. Pharmaceutics. 2022;14: pubmed publisher |
| Roelle S, Shukla N, Pham A, Bruchez A, Matreyek K. Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains. PLoS Biol. 2022;20:e3001738 pubmed publisher |
| David A, Parkinson N, Peacock T, Pairo Castineira E, Khanna T, Cobat A, et al. A common TMPRSS2 variant has a protective effect against severe COVID-19. Curr Res Transl Med. 2022;70:103333 pubmed publisher |
| Klouda T, Hao Y, Kim H, Kim J, Olejnik J, Hume A, et al. Interferon-alpha or -beta facilitates SARS-CoV-2 pulmonary vascular infection by inducing ACE2. Angiogenesis. 2021;: pubmed publisher |
| Youn J, Zhang Y, Wu Y, Cannesson M, Cai H. Therapeutic application of estrogen for COVID-19: Attenuation of SARS-CoV-2 spike protein and IL-6 stimulated, ACE2-dependent NOX2 activation, ROS production and MCP-1 upregulation in endothelial cells. Redox Biol. 2021;46:102099 pubmed publisher |
| Kim T, Jeon S, Jang Y, Gotina L, Won J, Ju Y, et al. Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion. Exp Mol Med. 2021;53:956-972 pubmed publisher |
| Peacock T, Goldhill D, Zhou J, Baillon L, Frise R, Swann O, et al. The furin cleavage site in the SARS-CoV-2 spike protein is required for transmission in ferrets. Nat Microbiol. 2021;6:899-909 pubmed publisher |
| Ou T, Mou H, Zhang L, Ojha A, Choe H, Farzan M. Hydroxychloroquine-mediated inhibition of SARS-CoV-2 entry is attenuated by TMPRSS2. PLoS Pathog. 2021;17:e1009212 pubmed publisher |
| Wang R, Simoneau C, Kulsuptrakul J, Bouhaddou M, Travisano K, Hayashi J, et al. Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses. Cell. 2021;184:106-119.e14 pubmed publisher |
