This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-RNA polymerase II CTD repeat YSPTSPS antibody [8WG16] - ChIP Grade
catalog :
ab817
quantity :
25 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
8WG16
reactivity :
fission yeast, Saccharomycetales, human, mouse, bovine, fruit fly , thale cress, roundworm
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, ChIP-Seq
citations: 133
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:500; loading ...; fig 3a
Guo Y, Manteiga J, Henninger J, Sabari B, Dall Agnese A, Hannett N, et al. Pol II phosphorylation regulates a switch between transcriptional and splicing condensates. Nature. 2019;572:543-548 pubmed publisher
  • ChIP-Seq; human; ; loading ...; fig 5a
Mayfield J, Irani S, Escobar E, Zhang Z, Burkholder N, Robinson M, et al. Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb. elife. 2019;8: pubmed publisher
  • ChIP-Seq; human; fig 3a
Liu X, Wu H, Krzisch M, Wu X, Graef J, Muffat J, et al. Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene. Cell. 2018;172:979-992.e6 pubmed publisher
  • immunocytochemistry; mouse; 1:200; loading ...; fig 1b
Bogolyubova I, Bogolyubov D. Detection of RNA Polymerase II in Mouse Embryos During Zygotic Genome Activation Using Immunocytochemistry. Methods Mol Biol. 2017;1605:147-159 pubmed publisher
  • western blot; human; loading ...; fig 4b
Aktas T, Avşar Ilık İ, Maticzka D, Bhardwaj V, Pessoa Rodrigues C, Mittler G, et al. DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome. Nature. 2017;544:115-119 pubmed publisher
  • chromatin immunoprecipitation; human; fig s5d
Shadle S, Zhong J, Campbell A, Conerly M, Jagannathan S, Wong C, et al. DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy. PLoS Genet. 2017;13:e1006658 pubmed publisher
  • chromatin immunoprecipitation; mouse; fig 4e
Zhang Y, Zhang J, An W, Wan Y, Ma S, Yin J, et al. Intron 1 GATA site enhances ALAS2 expression indispensably during erythroid differentiation. Nucleic Acids Res. 2017;45:657-671 pubmed publisher
  • chromatin immunoprecipitation; human; fig 6
Diamant G, Bahat A, Dikstein R. The elongation factor Spt5 facilitates transcription initiation for rapid induction of inflammatory-response genes. Nat Commun. 2016;7:11547 pubmed publisher
  • western blot; human; loading ...; fig 2d
Lu L, Fan D, Hu C, Worth M, Ma Z, Jiang J. Distributive O-GlcNAcylation on the Highly Repetitive C-Terminal Domain of RNA Polymerase II. Biochemistry. 2016;55:1149-58 pubmed publisher
  • chromatin immunoprecipitation; human; fig 3
M L, P P, T K, M P, E S, J P, et al. Essential role of HDAC6 in the regulation of PD-L1 in melanoma. Mol Oncol. 2016;10:735-750 pubmed publisher
  • chromatin immunoprecipitation; human; fig 4
Kreuz S, Holmes K, Tooze R, Lefevre P. Loss of PIM2 enhances the anti-proliferative effect of the pan-PIM kinase inhibitor AZD1208 in non-Hodgkin lymphomas. Mol Cancer. 2015;14:205 pubmed publisher
  • ChIP-Seq; thale cress; fig s4a
Zhai J, Bischof S, Wang H, Feng S, Lee T, Teng C, et al. A One Precursor One siRNA Model for Pol IV-Dependent siRNA Biogenesis. Cell. 2015;163:445-55 pubmed publisher
  • chromatin immunoprecipitation; human; fig 3d
Zhu J, Sammons M, Donahue G, Dou Z, Vedadi M, Getlik M, et al. Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth. Nature. 2015;525:206-11 pubmed publisher
  • ChIP-Seq; human; fig 6
  • ChIP-Seq; fission yeast; fig 2
  • western blot; fission yeast; 1:2000; fig s5
Sutani T, Sakata T, Nakato R, Masuda K, Ishibashi M, Yamashita D, et al. Condensin targets and reduces unwound DNA structures associated with transcription in mitotic chromosome condensation. Nat Commun. 2015;6:7815 pubmed publisher
  • chromatin immunoprecipitation; human; fig 6
Eid R, Demattei M, Episkopou H, Augé Gouillou C, Decottignies A, Grandin N, et al. Genetic Inactivation of ATRX Leads to a Decrease in the Amount of Telomeric Cohesin and Level of Telomere Transcription in Human Glioma Cells. Mol Cell Biol. 2015;35:2818-30 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 4c
Guendel I, Meltzer B, Baer A, Dever S, Valerie K, Guo J, et al. BRCA1 functions as a novel transcriptional cofactor in HIV-1 infection. Virol J. 2015;12:40 pubmed publisher
  • chromatin immunoprecipitation; human
Jiang Y, Yan B, Lai W, Shi Y, Xiao D, Jia J, et al. Repression of Hox genes by LMP1 in nasopharyngeal carcinoma and modulation of glycolytic pathway genes by HoxC8. Oncogene. 2015;34:6079-91 pubmed publisher
  • chromatin immunoprecipitation; fruit fly ; loading ...; fig 6c
  • western blot; fruit fly ; 1:500; loading ...; fig 6b
Dahlberg O, Shilkova O, Tang M, Holmqvist P, Mannervik M. P-TEFb, the super elongation complex and mediator regulate a subset of non-paused genes during early Drosophila embryo development. PLoS Genet. 2015;11:e1004971 pubmed publisher
  • chromatin immunoprecipitation; human
Suzuki A, Makinoshima H, Wakaguri H, Esumi H, Sugano S, Kohno T, et al. Aberrant transcriptional regulations in cancers: genome, transcriptome and epigenome analysis of lung adenocarcinoma cell lines. Nucleic Acids Res. 2014;42:13557-72 pubmed publisher
  • ChIP-Seq; human
Matsumoto K, Suzuki A, Wakaguri H, Sugano S, Suzuki Y. Construction of mate pair full-length cDNAs libraries and characterization of transcriptional start sites and termination sites. Nucleic Acids Res. 2014;42:e125 pubmed publisher
  • western blot; Saccharomycetales
Schulz D, Pirkl N, Lehmann E, Cramer P. Rpb4 subunit functions mainly in mRNA synthesis by RNA polymerase II. J Biol Chem. 2014;289:17446-52 pubmed publisher
  • chromatin immunoprecipitation; mouse
Seki M, Masaki H, Arauchi T, Nakauchi H, Sugano S, Suzuki Y. A comparison of the rest complex binding patterns in embryonic stem cells and epiblast stem cells. PLoS ONE. 2014;9:e95374 pubmed publisher
  • immunohistochemistry; thale cress; 1:100
Shu H, Nakamura M, Siretskiy A, Borghi L, Moraes I, Wildhaber T, et al. Arabidopsis replacement histone variant H3.3 occupies promoters of regulated genes. Genome Biol. 2014;15:R62 pubmed publisher
  • chromatin immunoprecipitation; human
Miao F, Chen Z, Zhang L, Wang J, Gao H, Wu X, et al. RNA-sequencing analysis of high glucose-treated monocytes reveals novel transcriptome signatures and associated epigenetic profiles. Physiol Genomics. 2013;45:287-99 pubmed publisher
  • chromatin immunoprecipitation; human
Wu L, Runkle C, Jin H, Li J, Yang X, Kuzel T, et al. CCN3/NOV gene expression in human prostate cancer is directly suppressed by the androgen receptor. Oncogene. 2014;33:504-13 pubmed publisher
  • chromatin immunoprecipitation; human
  • chromatin immunoprecipitation; mouse
Estarás C, Fueyo R, Akizu N, Beltran S, Martínez Balbás M. RNA polymerase II progression through H3K27me3-enriched gene bodies requires JMJD3 histone demethylase. Mol Biol Cell. 2013;24:351-60 pubmed publisher
  • chromatin immunoprecipitation; mouse
Zediak V, Johnnidis J, Wherry E, Berger S. Cutting edge: persistently open chromatin at effector gene loci in resting memory CD8+ T cells independent of transcriptional status. J Immunol. 2011;186:2705-9 pubmed publisher
  • chromatin immunoprecipitation; roundworm ; 2-5 ug
Rechtsteiner A, Ercan S, Takasaki T, Phippen T, Egelhofer T, Wang W, et al. The histone H3K36 methyltransferase MES-4 acts epigenetically to transmit the memory of germline gene expression to progeny. PLoS Genet. 2010;6:e1001091 pubmed publisher
Su C, Lu F, Soldan S, Lamontagne R, Tang H, Napoletani G, et al. EBNA2 driven enhancer switching at the CIITA-DEXI locus suppresses HLA class II gene expression during EBV infection of B-lymphocytes. PLoS Pathog. 2021;17:e1009834 pubmed publisher
Shin S, Zhou H, He C, Wei Y, Wang Y, Shingu T, et al. Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency. Nat Commun. 2021;12:3005 pubmed publisher
Estell C, Davidson L, Steketee P, Monier A, West S. ZC3H4 restricts non-coding transcription in human cells. elife. 2021;10: pubmed publisher
Castañeda A, Didychuk A, Louder R, McCollum C, Davis Z, Nogales E, et al. The gammaherpesviral TATA-box-binding protein directly interacts with the CTD of host RNA Pol II to direct late gene transcription. PLoS Pathog. 2020;16:e1008843 pubmed publisher
Zhou H, Møhlenberg M, Terczyńska Dyla E, Winther K, Hansen N, Vad Nielsen J, et al. The IFNL4 Gene Is a Noncanonical Interferon Gene with a Unique but Evolutionarily Conserved Regulation. J Virol. 2020;94: pubmed publisher
Bogutz A, Brind Amour J, Kobayashi H, Jensen K, Nakabayashi K, Imai H, et al. Evolution of imprinting via lineage-specific insertion of retroviral promoters. Nat Commun. 2019;10:5674 pubmed publisher
Eaton J, Francis L, Davidson L, West S. A unified allosteric/torpedo mechanism for transcriptional termination on human protein-coding genes. Genes Dev. 2019;: pubmed publisher
Roy A, Ghosh A, Kumar B, Chandran B. IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP. elife. 2019;8: pubmed publisher
Didychuk A, Castañeda A, Kushnir L, Huang C, Glaunsinger B. Conserved CxnC motifs in Kaposi's sarcoma-associated herpesvirus ORF66 are required for viral late gene expression and are essential for its interaction with ORF34. J Virol. 2019;: pubmed publisher
Meers M, Bryson T, Henikoff J, Henikoff S. Improved CUT&RUN chromatin profiling tools. elife. 2019;8: pubmed publisher
Kwon P, Kim H, Kim S, Kang B, Yi H, Ku H, et al. The poly(C) motif in the proximal promoter region of D-box binding protein (Dbp) drives its high-amplitude oscillation. Mol Cell Biol. 2019;: pubmed publisher
Chen C, Shu J, Li C, Thapa R, Nguyen V, Yu K, et al. RNA polymerase II-independent recruitment of SPT6L at transcription start sites in Arabidopsis. Nucleic Acids Res. 2019;47:6714-6725 pubmed publisher
Fiorucci A, Bourbousse C, Concia L, Rougée M, Deton Cabanillas A, Zabulon G, et al. Arabidopsis S2Lb links AtCOMPASS-like and SDG2 activity in H3K4me3 independently from histone H2B monoubiquitination. Genome Biol. 2019;20:100 pubmed publisher
Maslon M, Braunschweig U, Aitken S, Mann A, Kilanowski F, Hunter C, et al. A slow transcription rate causes embryonic lethality and perturbs kinetic coupling of neuronal genes. EMBO J. 2019;38: pubmed publisher
Nagashima R, Hibino K, Ashwin S, Babokhov M, Fujishiro S, Imai R, et al. Single nucleosome imaging reveals loose genome chromatin networks via active RNA polymerase II. J Cell Biol. 2019;218:1511-1530 pubmed publisher
Dremel S, DeLuca N. Genome replication affects transcription factor binding mediating the cascade of herpes simplex virus transcription. Proc Natl Acad Sci U S A. 2019;116:3734-3739 pubmed publisher
Wang H, Long Q, Tang S, Xiao Q, Gao C, Zhao Q, et al. Histone demethylase KDM3A is required for enhancer activation of hippo target genes in colorectal cancer. Nucleic Acids Res. 2019;47:2349-2364 pubmed publisher
Saeed U, Kim J, Piracha Z, Kwon H, Jung J, Chwae Y, et al. Parvulin 14 and Parvulin 17 Bind to HBx and cccDNA and Upregulate Hepatitis B Virus Replication from cccDNA to Virion in an HBx-Dependent Manner. J Virol. 2019;93: pubmed publisher
Castañeda A, Glaunsinger B. The Interaction between ORF18 and ORF30 Is Required for Late Gene Expression in Kaposi's Sarcoma-Associated Herpesvirus. J Virol. 2019;93: pubmed publisher
Zhao T, Tao X, Feng S, Wang L, Hong H, Ma W, et al. LncRNAs in polyploid cotton interspecific hybrids are derived from transposon neofunctionalization. Genome Biol. 2018;19:195 pubmed publisher
Buxade M, Huerga Encabo H, Riera Borrull M, Quintana Gallardo L, López Cotarelo P, Tellechea M, et al. Macrophage-specific MHCII expression is regulated by a remote Ciita enhancer controlled by NFAT5. J Exp Med. 2018;215:2901-2918 pubmed publisher
Paul S, Ghosh S, Mandal S, Sau S, Pal M. NRF2 transcriptionally activates the heat shock factor 1 promoter under oxidative stress and affects survival and migration potential of MCF7 cells. J Biol Chem. 2018;293:19303-19316 pubmed publisher
Zanconato F, Battilana G, Forcato M, Filippi L, Azzolin L, Manfrin A, et al. Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4. Nat Med. 2018;24:1599-1610 pubmed publisher
Sun Z, Zhu M, Lv P, Cheng L, Wang Q, Tian P, et al. The Long Noncoding RNA Lncenc1 Maintains Naive States of Mouse ESCs by Promoting the Glycolysis Pathway. Stem Cell Reports. 2018;11:741-755 pubmed publisher
Alhazmi A, Mack M, Petencin A, Nelson H, Rolle T, Hiegel J, et al. WITHDRAWN: The chromatin remodeling complex NURF localizes to gene bodies and is required for mRNA processing. J Biol Chem. 2018;: pubmed publisher
Watanabe T, Cui X, Yuan Z, Qi H, Lin H. MIWI2 targets RNAs transcribed from piRNA-dependent regions to drive DNA methylation in mouse prospermatogonia. EMBO J. 2018;37: pubmed publisher
Li S, Xu R, Li A, Liu K, Gu L, Li M, et al. SMA1, a homolog of the splicing factor Prp28, has a multifaceted role in miRNA biogenesis in Arabidopsis. Nucleic Acids Res. 2018;46:9148-9159 pubmed publisher
Imamura K, Takaya A, Ishida Y, Fukuoka Y, Taya T, Nakaki R, et al. Diminished nuclear RNA decay upon Salmonella infection upregulates antibacterial noncoding RNAs. EMBO J. 2018;37: pubmed publisher
Tyssowski K, DeStefino N, Cho J, Dunn C, Poston R, Carty C, et al. Different Neuronal Activity Patterns Induce Different Gene Expression Programs. Neuron. 2018;98:530-546.e11 pubmed publisher
de Bruyckere E, Simon R, Nestel S, Heimrich B, Kätzel D, Egorov A, et al. Stability and Function of Hippocampal Mossy Fiber Synapses Depend on Bcl11b/Ctip2. Front Mol Neurosci. 2018;11:103 pubmed publisher
Miao Y, Ajami N, Huang T, Lin F, Lou C, Wang Y, et al. Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function. Nat Commun. 2018;9:292 pubmed publisher
Bu Y, Yoshida A, Chitnis N, Altman B, Tameire F, Oran A, et al. A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival. Nat Cell Biol. 2018;20:104-115 pubmed publisher
Michelini F, Pitchiaya S, Vitelli V, Sharma S, Gioia U, Pessina F, et al. Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks. Nat Cell Biol. 2017;19:1400-1411 pubmed publisher
Damodaren N, Van Eeuwen T, Zamel J, Lin Shiao E, Kalisman N, Murakami K. Def1 interacts with TFIIH and modulates RNA polymerase II transcription. Proc Natl Acad Sci U S A. 2017;114:13230-13235 pubmed publisher
Tan C, Yu C, Song Z, Zou H, Xu X, Liu J. Expression of MicroRNA-29a Regulated by Yes-Associated Protein Modulates the Neurite Outgrowth in N2a Cells. Biomed Res Int. 2017;2017:5251236 pubmed publisher
Miki T, Carl S, Großhans H. Two distinct transcription termination modes dictated by promoters. Genes Dev. 2017;31:1870-1879 pubmed publisher
Isoda T, Moore A, He Z, Chandra V, Aida M, Denholtz M, et al. Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate. Cell. 2017;171:103-119.e18 pubmed publisher
Seo H, Choi Y, Kim M, Kang K, Urano T, Lee D. The 19S proteasome is directly involved in the regulation of heterochromatin spreading in fission yeast. J Biol Chem. 2017;292:17144-17155 pubmed publisher
Touat Todeschini L, Shichino Y, Dangin M, Thierry Mieg N, Gilquin B, Hiriart E, et al. Selective termination of lncRNA transcription promotes heterochromatin silencing and cell differentiation. EMBO J. 2017;36:2626-2641 pubmed publisher
Gates L, Shi J, Rohira A, Feng Q, Zhu B, Bedford M, et al. Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation. J Biol Chem. 2017;292:14456-14472 pubmed publisher
Zhang X, Chiang H, Wang Y, Zhang C, Smith S, Zhao X, et al. Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis. Nat Commun. 2017;8:15908 pubmed publisher
Casciello F, Al Ejeh F, Kelly G, Brennan D, Ngiow S, Young A, et al. G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis. Proc Natl Acad Sci U S A. 2017;114:7077-7082 pubmed publisher
He R, Kidder B. H3K4 demethylase KDM5B regulates global dynamics of transcription elongation and alternative splicing in embryonic stem cells. Nucleic Acids Res. 2017;45:6427-6441 pubmed publisher
Timblin G, Xie L, Tjian R, Schlissel M. Dual Mechanism of Rag Gene Repression by c-Myb during Pre-B Cell Proliferation. Mol Cell Biol. 2017;37: pubmed publisher
Esnault C, Gualdrini F, Horswell S, Kelly G, Stewart A, East P, et al. ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a Chromatin Modification Cascade Associated with Transcription. Mol Cell. 2017;65:1081-1095.e5 pubmed publisher
Skene P, Henikoff S. An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites. elife. 2017;6: pubmed publisher
Fonseca Costa S, Wegmann D, Ripperger J. Normalisation against Circadian and Age-Related Disturbances Enables Robust Detection of Gene Expression Changes in Liver of Aged Mice. PLoS ONE. 2017;12:e0169615 pubmed publisher
Ammosova T, Washington K, Rotimi J, Kumari N, Smith K, Niu X, et al. Protein Phosphatase-1 Regulates Expression of Neuregulin-1. Biology (Basel). 2016;5: pubmed
Brzezinka K, Altmann S, Czesnick H, Nicolas P, Gorka M, Benke E, et al. Arabidopsis FORGETTER1 mediates stress-induced chromatin memory through nucleosome remodeling. elife. 2016;5: pubmed publisher
Yang Y, La H, Tang K, Miki D, Yang L, Wang B, et al. SAC3B, a central component of the mRNA export complex TREX-2, is required for prevention of epigenetic gene silencing in Arabidopsis. Nucleic Acids Res. 2017;45:181-197 pubmed publisher
Veluchamy A, Jégu T, Ariel F, Latrasse D, Mariappan K, Kim S, et al. LHP1 Regulates H3K27me3 Spreading and Shapes the Three-Dimensional Conformation of the Arabidopsis Genome. PLoS ONE. 2016;11:e0158936 pubmed publisher
Cheng W, Tian L, Wang B, Qi Y, Huang W, Li H, et al. Downregulation of HP1? suppresses proliferation of cholangiocarcinoma by restoring SFRP1 expression. Oncotarget. 2016;7:48107-48119 pubmed publisher
Bhardwaj S, Schlackow M, Rabajdova M, Gullerova M. Transcription facilitates sister chromatid cohesion on chromosomal arms. Nucleic Acids Res. 2016;44:6676-92 pubmed publisher
Kos I, Patterson M, Znaidi S, Kaloriti D, da Silva Dantas A, Herrero de Dios C, et al. Mechanisms Underlying the Delayed Activation of the Cap1 Transcription Factor in Candida albicans following Combinatorial Oxidative and Cationic Stress Important for Phagocytic Potency. MBio. 2016;7:e00331 pubmed publisher
Poli J, Gerhold C, Tosi A, Hustedt N, Seeber A, Sack R, et al. Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress. Genes Dev. 2016;30:337-54 pubmed publisher
Woo Y, Shin Y, Hwang J, Hwang Y, Lee S, Park E, et al. Epigenetic silencing of the MUPCDH gene as a possible prognostic biomarker for cyst growth in ADPKD. Sci Rep. 2015;5:15238 pubmed publisher
Deng X, Zhou H, Zhang G, Wang W, Mao L, Zhou X, et al. Sgf73, a subunit of SAGA complex, is required for the assembly of RITS complex in fission yeast. Sci Rep. 2015;5:14707 pubmed publisher
Sun J, Rockowitz S, Xie Q, Ashery Padan R, Zheng D, Cvekl A. Identification of in vivo DNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development. Nucleic Acids Res. 2015;43:6827-46 pubmed publisher
Maekawa S, Imamachi N, Irie T, Tani H, Matsumoto K, Mizutani R, et al. Analysis of RNA decay factor mediated RNA stability contributions on RNA abundance. BMC Genomics. 2015;16:154 pubmed publisher
Liu H, Banerjee T, Guan X, Freitas M, Parvin J. The chromatin scaffold protein SAFB1 localizes SUMO-1 to the promoters of ribosomal protein genes to facilitate transcription initiation and splicing. Nucleic Acids Res. 2015;43:3605-13 pubmed publisher
Agarwal P, Enroth S, Teichmann M, Jernberg Wiklund H, Smit A, Westermark B, et al. Growth signals employ CGGBP1 to suppress transcription of Alu-SINEs. Cell Cycle. 2016;15:1558-71 pubmed publisher
Stubbs S, Conrad N. Depletion of REF/Aly alters gene expression and reduces RNA polymerase II occupancy. Nucleic Acids Res. 2015;43:504-19 pubmed publisher
Basnet H, Su X, Tan Y, Meisenhelder J, Merkurjev D, Ohgi K, et al. Tyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongation. Nature. 2014;516:267-71 pubmed publisher
Moquet Torcy G, Tolza C, Piechaczyk M, Jariel Encontre I. Transcriptional complexity and roles of Fra-1/AP-1 at the uPA/Plau locus in aggressive breast cancer. Nucleic Acids Res. 2014;42:11011-24 pubmed publisher
Jullien J, Miyamoto K, Pasque V, Allen G, Bradshaw C, Garrett N, et al. Hierarchical molecular events driven by oocyte-specific factors lead to rapid and extensive reprogramming. Mol Cell. 2014;55:524-36 pubmed publisher
Roy D, Paul A, Roy A, Ghosh R, Ganguly P, Chaudhuri S. Differential acetylation of histone H3 at the regulatory region of OsDREB1b promoter facilitates chromatin remodelling and transcription activation during cold stress. PLoS ONE. 2014;9:e100343 pubmed publisher
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Yang S, Li W, Qi S, Gai K, Chen Y, Suo J, et al. The highly expressed methionine synthase gene of Neurospora crassa is positively regulated by its proximal heterochromatic region. Nucleic Acids Res. 2014;42:6183-95 pubmed publisher
Shin M, Natsuume M, Matsumoto T, Hanaoka M, Imai M, Iijima K, et al. Sense transgene-induced post-transcriptional gene silencing in tobacco compromises the splicing of endogenous counterpart genes. PLoS ONE. 2014;9:e87869 pubmed publisher
Dürr J, Lolas I, Sørensen B, Schubert V, Houben A, Melzer M, et al. The transcript elongation factor SPT4/SPT5 is involved in auxin-related gene expression in Arabidopsis. Nucleic Acids Res. 2014;42:4332-47 pubmed publisher
Gentsch G, Owens N, Martin S, Piccinelli P, Faial T, Trotter M, et al. In vivo T-box transcription factor profiling reveals joint regulation of embryonic neuromesodermal bipotency. Cell Rep. 2013;4:1185-96 pubmed publisher
Jia J, Parikh H, Xiao W, Hoskins J, Pflicke H, Liu X, et al. An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancer. BMC Med Genomics. 2013;6:33 pubmed publisher
Schaaf C, Misulovin Z, Gause M, Koenig A, Gohara D, Watson A, et al. Cohesin and polycomb proteins functionally interact to control transcription at silenced and active genes. PLoS Genet. 2013;9:e1003560 pubmed publisher
Golla U, Singh V, Azad G, Singh P, Verma N, Mandal P, et al. Sen1p contributes to genomic integrity by regulating expression of ribonucleotide reductase 1 (RNR1) in Saccharomyces cerevisiae. PLoS ONE. 2013;8:e64798 pubmed publisher
Singh S, Maeda K, Eid M, Almofty S, Ono M, Pham P, et al. GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy. Nat Commun. 2013;4:1830 pubmed publisher
Zhao W, Breese E, Bowers A, Hoggatt J, Pelus L, Broxmeyer H, et al. SIMPL enhancement of tumor necrosis factor-? dependent p65-MED1 complex formation is required for mammalian hematopoietic stem and progenitor cell function. PLoS ONE. 2013;8:e61123 pubmed publisher
Kammel C, Thomaier M, Sørensen B, Schubert T, Längst G, Grasser M, et al. Arabidopsis DEAD-box RNA helicase UAP56 interacts with both RNA and DNA as well as with mRNA export factors. PLoS ONE. 2013;8:e60644 pubmed publisher
Shin J, Wang H, Lee J, Dinwiddie B, Belostotsky D, Chekanova J. The role of the Arabidopsis Exosome in siRNA-independent silencing of heterochromatic loci. PLoS Genet. 2013;9:e1003411 pubmed publisher
Witham J, Ouboussad L, Lefevre P. A NF-?B-dependent dual promoter-enhancer initiates the lipopolysaccharide-mediated transcriptional activation of the chicken lysozyme in macrophages. PLoS ONE. 2013;8:e59389 pubmed publisher
Mirón García M, Garrido Godino A, García Molinero V, Hernández Torres F, Rodriguez Navarro S, Navarro F. The prefoldin bud27 mediates the assembly of the eukaryotic RNA polymerases in an rpb5-dependent manner. PLoS Genet. 2013;9:e1003297 pubmed publisher
Ding Y, Ndamukong I, Xu Z, Lapko H, Fromm M, Avramova Z. ATX1-generated H3K4me3 is required for efficient elongation of transcription, not initiation, at ATX1-regulated genes. PLoS Genet. 2012;8:e1003111 pubmed publisher
Kimmig P, Diaz M, Zheng J, Williams C, Lang A, Arag n T, et al. The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis. elife. 2012;1:e00048 pubmed publisher
Lichtinger M, Ingram R, Hannah R, Müller D, Clarke D, Assi S, et al. RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis. EMBO J. 2012;31:4318-33 pubmed publisher
Nicol S, Bray S, Black H, Lorimore S, Wright E, Lane D, et al. The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell-cycle arrest after DNA damage. Oncogene. 2013;32:3461-9 pubmed publisher
Thorne J, Ouboussad L, Lefevre P. Heterochromatin protein 1 gamma and I?B kinase alpha interdependence during tumour necrosis factor gene transcription elongation in activated macrophages. Nucleic Acids Res. 2012;40:7676-89 pubmed publisher
de Vries M, Vosters S, Merkx G, D Hauwers K, Wansink D, Ramos L, et al. Human male meiotic sex chromosome inactivation. PLoS ONE. 2012;7:e31485 pubmed publisher
May D, Blow M, Kaplan T, McCulley D, Jensen B, Akiyama J, et al. Large-scale discovery of enhancers from human heart tissue. Nat Genet. 2011;44:89-93 pubmed publisher
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product information
CatalogNumber :
ab817
ItemName :
Anti-RNA polymerase II CTD repeat YSPTSPS antibody [8WG16] - ChIP Grade
Product Type :
Primary Antibodies
Host Species :
Mouse
Clonality :
Monoclonal
Conjugate :
Not Conjugated
Antigen Modification :
No Modifications
Clone Name :
8WG16
Size :
25 µg
SpeciesSummary :
At, Ce, Cow, Dm, Hu, Ms, N cra, Ql, Rice, S pom, Sc, Xl
Uses :
ChIP, CHIPseq, Flow Cyt, ICC/IF, IHC - Wmt, IP, WB
Size Note :
Other sizes available: 100 µg,123 mg
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK