This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Ascent Scientific
product type :
antibody
product name :
c-Fos antibody
catalog :
ab7963
quantity :
1 ml
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 48
Published Application/Species/DilutionReference
  • immunohistochemistry; mouse; fig 1
Yuan P, Grutzendler J. Attenuation of β-Amyloid Deposition and Neurotoxicity by Chemogenetic Modulation of Neural Activity. J Neurosci. 2016;36:632-41 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 7
  • immunocytochemistry; mouse; fig 7
  • western blot; mouse
Thomas A, Eijgelaar W, Daemen M, Newby A. Foam Cell Formation In Vivo Converts Macrophages to a Pro-Fibrotic Phenotype. PLoS ONE. 2015;10:e0128163 pubmed publisher
  • western blot; human; fig 4A
Lu S, Yang Y, Du Y, Cao L, Li M, Shen C, et al. The transcription factor c-Fos coordinates with histone lysine-specific demethylase 2A to activate the expression of cyclooxygenase-2. Oncotarget. 2015;6:34704-17 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500
Jeong J, Lee D, Blouet C, Ruiz H, Buettner C, Chua S, et al. Cholinergic neurons in the dorsomedial hypothalamus regulate mouse brown adipose tissue metabolism. Mol Metab. 2015;4:483-92 pubmed publisher
  • western blot; rat; fig 4
Wang J, Cao Y, Li Q, Yang Y, Jin M, Chen D, et al. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation. Autophagy. 2015;11:2057-2073 pubmed
  • immunohistochemistry; mouse; 1:1000
Jones J, Tackenberg M, McMahon D. Manipulating circadian clock neuron firing rate resets molecular circadian rhythms and behavior. Nat Neurosci. 2015;18:373-5 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:1000
Rajput P, Lyden P, Chen B, Lamb J, Pereira B, Lamb A, et al. Protease activated receptor-1 mediates cytotoxicity during ischemia using in vivo and in vitro models. Neuroscience. 2014;281:229-40 pubmed publisher
  • immunohistochemistry; rat; 1:800
Shen W, Hu X, Liu Y, Han Y, Chen L, Wang C, et al. CXCL12 in astrocytes contributes to bone cancer pain through CXCR4-mediated neuronal sensitization and glial activation in rat spinal cord. J Neuroinflammation. 2014;11:75 pubmed publisher
  • western blot; mouse
Brooks E, Little D, Arumugam R, Sun B, Curtis S, Demaster A, et al. Pathogenesis of growth failure and partial reversal with gene therapy in murine and canine Glycogen Storage Disease type Ia. Mol Genet Metab. 2013;109:161-70 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:500
Liu X, Zeng J, Zhou A, Theodorsson E, Fahrenkrug J, Reinscheid R. Molecular fingerprint of neuropeptide S-producing neurons in the mouse brain. J Comp Neurol. 2011;519:1847-66 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:750
Groessl F, Jeong J, Talmage D, Role L, Jo Y. Overnight fasting regulates inhibitory tone to cholinergic neurons of the dorsomedial nucleus of the hypothalamus. PLoS ONE. 2013;8:e60828 pubmed publisher
  • immunocytochemistry; mouse
Yoshinaga S, Sato T, Hirakane M, Esaki K, Hamaguchi T, Haga-Yamanaka S, et al. Structure of the mouse sex peptide pheromone ESP1 reveals a molecular basis for specific binding to the class C G-protein-coupled vomeronasal receptor. J Biol Chem. 2013;288:16064-72 pubmed publisher
Lei J, Sun T, Lumb B, You H. Roles of the periaqueductal gray in descending facilitatory and inhibitory controls of intramuscular hypertonic saline induced muscle nociception. Exp Neurol. 2014;257:88-94 pubmed publisher
Krzeszinski J, Wei W, Huynh H, Jin Z, Wang X, Chang T, et al. miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2. Nature. 2014;512:431-5 pubmed publisher
Smithson L, Krol K, Kawaja M. Neuronal degeneration associated with sympathosensory plexuses in the trigeminal ganglia of aged mice that overexpress nerve growth factor. Neurobiol Aging. 2014;35:2812-21 pubmed publisher
Mladenova D, Pangon L, Currey N, Ng I, Musgrove E, Grey S, et al. Sulindac activates NF-κB signaling in colon cancer cells. Cell Commun Signal. 2013;11:73 pubmed publisher
Friemel C, Spanagel R, Schneider M. Reward sensitivity for a palatable food reward peaks during pubertal developmental in rats. Front Behav Neurosci. 2010;4: pubmed
Yamamura S, Kawakami K, Hirata H, Ueno K, Saini S, Majid S, et al. Oncogenic functions of secreted Frizzled-related protein 2 in human renal cancer. Mol Cancer Ther. 2010;9:1680-7 pubmed publisher
Vendrell J, Robertson K, Ravel P, Bray S, Bajard A, Purdie C, et al. A candidate molecular signature associated with tamoxifen failure in primary breast cancer. Breast Cancer Res. 2008;10:R88 pubmed publisher
Young J, Shapiro M. Double dissociation and hierarchical organization of strategy switches and reversals in the rat PFC. Behav Neurosci. 2009;123:1028-35 pubmed publisher
Ohira K, Furuta T, Hioki H, Nakamura K, Kuramoto E, Tanaka Y, et al. Ischemia-induced neurogenesis of neocortical layer 1 progenitor cells. Nat Neurosci. 2010;13:173-9 pubmed publisher
Ginsberg M, Czeko E, Muller P, Ren Z, Chen X, Darnell J. Amino acid residues required for physical and cooperative transcriptional interaction of STAT3 and AP-1 proteins c-Jun and c-Fos. Mol Cell Biol. 2007;27:6300-8 pubmed
Schwartz C, SMOTHERMAN M. Mapping vocalization-related immediate early gene expression in echolocating bats. Behav Brain Res. 2011;224:358-68 pubmed publisher
Sajadi K, Lin D, Steward J, Balog B, Dissaranan C, Zaszczurynski P, et al. Pudendal nerve stretch reduces external urethral sphincter activity in rats. J Urol. 2012;188:1389-95 pubmed publisher
Liu L, Shenoy M, Pasricha P. The analgesic effects of the GABAB receptor agonist, baclofen, in a rodent model of functional dyspepsia. Neurogastroenterol Motil. 2011;23:356-61, e160-1 pubmed publisher
Zhao J, Lee M, Momin A, Cendan C, Shepherd S, Baker M, et al. Small RNAs control sodium channel expression, nociceptor excitability, and pain thresholds. J Neurosci. 2010;30:10860-71 pubmed publisher
Zhang J, Jahr H, Luo C, Klein C, Van Kolen K, Ver Donck L, et al. Obestatin induction of early-response gene expression in gastrointestinal and adipose tissues and the mediatory role of G protein-coupled receptor, GPR39. Mol Endocrinol. 2008;22:1464-75 pubmed publisher
Tsuji-Naito K. Aldehydic components of cinnamon bark extract suppresses RANKL-induced osteoclastogenesis through NFATc1 downregulation. Bioorg Med Chem. 2008;16:9176-83 pubmed publisher
Einspahr J, Bowden G, Alberts D, McKenzie N, Saboda K, Warneke J, et al. Cross-validation of murine UV signal transduction pathways in human skin. Photochem Photobiol. 2008;84:463-76 pubmed publisher
Park E, Kim S, Youn D. NMDA receptor, PKC and ERK prevent fos expression induced by the activation of group I metabotropic glutamate receptors in the spinal trigeminal subnucleus oralis. Mol Cells. 2010;30:461-6 pubmed publisher
Pitcher M, Nieto F, Cervero F. Stimulation of cutaneous low threshold mechanoreceptors in mice after intracolonic capsaicin increases spinal c-Fos labeling in an NKCC1-dependent fashion. J Pain. 2013;14:57-65 pubmed publisher
Hahm T, Ahn H, Ryu S, Gwak M, Choi S, Kim J, et al. Combined carbamazepine and pregabalin therapy in a rat model of neuropathic pain. Br J Anaesth. 2012;109:968-74 pubmed publisher
Blanquicett C, Kang B, Ritzenthaler J, Jones D, Hart C. Oxidative stress modulates PPAR gamma in vascular endothelial cells. Free Radic Biol Med. 2010;48:1618-25 pubmed publisher
Valero J, España J, Parra-Damas A, Martín E, Rodriguez-Alvarez J, Saura C. Short-term environmental enrichment rescues adult neurogenesis and memory deficits in APP(Sw,Ind) transgenic mice. PLoS ONE. 2011;6:e16832 pubmed publisher
Chen Y, Lei J, Jin L, Tan Y, You H. Dynamic variations of c-Fos expression in the spinal cord exposed to intramuscular hypertonic saline-induced muscle nociception. Eur J Pain. 2013;17:336-46 pubmed publisher
Raskin K, De Gendt K, Duittoz A, Liere P, Verhoeven G, Tronche F, et al. Conditional inactivation of androgen receptor gene in the nervous system: effects on male behavioral and neuroendocrine responses. J Neurosci. 2009;29:4461-70 pubmed publisher
Huo F, Huang F, Lv B, Chen T, Feng J, Qu C, et al. Activation of serotonin 1A receptors in ventrolateral orbital cortex depresses persistent nociception: a presynaptic inhibition mechanism. Neurochem Int. 2010;57:749-55 pubmed publisher
Lewandowska U, Szewczyk K, Owczarek K, Hrabec Z, Podsedek A, Sosnowska D, et al. Procyanidins from evening primrose (Oenothera paradoxa) defatted seeds inhibit invasiveness of breast cancer cells and modulate the expression of selected genes involved in angiogenesis, metastasis, and apoptosis. Nutr Cancer. 2013;65:1219-31 pubmed publisher
Zhao T, Liu X, Zhen X, Guo S. Levo-tetrahydropalmatine retards the growth of ectopic endometrial implants and alleviates generalized hyperalgesia in experimentally induced endometriosis in rats. Reprod Sci. 2011;18:28-45 pubmed publisher
Sohn Y, Kang H, Kim K, Park S, Sohn N, Jung H, et al. Protective effects of natrii sulfas on cerebral focal ischemia induced by MCAO in rats. Am J Chin Med. 2009;37:273-93 pubmed
Bonner J, Connors T, Silverman W, Kowalski D, Lemay M, Fischer I. Grafted neural progenitors integrate and restore synaptic connectivity across the injured spinal cord. J Neurosci. 2011;31:4675-86 pubmed publisher
Almeida M, Muchow M, Boikos S, Bauer A, Griffin K, Tsang K, et al. Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling. Hum Mol Genet. 2010;19:1387-98 pubmed publisher
Sun M, Pang J, Chen S, Kuo P, Chen K, Kao L, et al. Photoreceptor protection against light damage by AAV-mediated overexpression of heme oxygenase-1. Invest Ophthalmol Vis Sci. 2007;48:5699-707 pubmed
Sajan F, Martiniuk F, Marcus D, Frey W, Hite R, Bordayo E, et al. Apoptotic gene expression in Alzheimer's disease hippocampal tissue. Am J Alzheimers Dis Other Demen. 2007;22:319-28 pubmed
Feng J, Huo F, Jia N, Qu C, Liu J, Li Y, et al. Activation of mu-opioid receptors in thalamic nucleus submedius depresses bee venom-evoked spinal c-Fos expression and flinching behavior. Neuroscience. 2009;161:554-60 pubmed publisher
Rajkumar R, See L, Dawe G. Acute antipsychotic treatments induce distinct c-Fos expression patterns in appetite-related neuronal structures of the rat brain. Brain Res. 2013;1508:34-43 pubmed publisher
Han B, Rorke E, Adhikary G, Chew Y, Xu W, Eckert R. Suppression of AP1 transcription factor function in keratinocyte suppresses differentiation. PLoS ONE. 2012;7:e36941 pubmed publisher
Spurlock C, Aune Z, Tossberg J, Collins P, Aune J, Huston J, et al. Increased sensitivity to apoptosis induced by methotrexate is mediated by JNK. Arthritis Rheum. 2011;63:2606-16 pubmed publisher
product information
Catalog Number :
ab7963
Product Name :
c-Fos antibody
Host Species :
Rabbit
Clonality :
polyclonal
Product Type :
Primary antibodies
Size :
1 ml
SwissProtID :
P01100
Isotype :
IgG
CrossReactivity :
Reacts with: Human, Mouse, Rat.
Application Summary :
Flow Cyt, IHC (PFA fixed), IHC-P, IP, WB
company information
Abcam
330 Cambridge Science Park
Cambridge
CB4 0FL UK
orders@abcam.com
44 (0)1223 696000

1 Kendall Square, Ste 341
Cambridge, MA 02139-1517
USA
us.orders@abcam.com
617 225 2272, 888-77-ABCAM (22226)

www.abcam.com
888-7722226
headquarters: UK