This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-Melanoma antibody [HMB45 + M2-7C10 + M2-9E3]
catalog :
ab732
quantity :
250 µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
HMB45 + M2-7C10 + M2-9E3
reactivity :
human, mouse
application :
immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 18
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:200; loading ...; fig s1a
Catalano A, Adlesic M, Kaltenbacher T, Klar R, Albers J, Seidel P, et al. Sensitivity and Resistance of Oncogenic RAS-Driven Tumors to Dual MEK and ERK Inhibition. Cancers (Basel). 2021;13: pubmed publisher
  • immunohistochemistry - paraffin section; human
  • immunohistochemistry; human
Lin J, Izar B, Wang S, Yapp C, Mei S, Shah P, et al. Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes. elife. 2018;7: pubmed publisher
  • flow cytometry; human; fig 1
Galore Haskel G, Nemlich Y, Greenberg E, Ashkenazi S, Hakim M, Itzhaki O, et al. A novel immune resistance mechanism of melanoma cells controlled by the ADAR1 enzyme. Oncotarget. 2015;6:28999-9015 pubmed publisher
Monteiro C, Miarka L, Perea García M, Priego N, García Gómez P, Álvaro Espinosa L, et al. Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism. Nat Med. 2022;28:752-765 pubmed publisher
Li Z, Wang C, Deng H, Wu J, Huang H, Sun R, et al. Robust Photodynamic Therapy Using 5-ALA-Incorporated Nanocomplexes Cures Metastatic Melanoma through Priming of CD4+CD8+ Double Positive T Cells. Adv Sci (Weinh). 2019;6:1802057 pubmed publisher
Malcov Brog H, Alpert A, Golan T, Parikh S, Nordlinger A, Netti F, et al. UV-Protection Timer Controls Linkage between Stress and Pigmentation Skin Protection Systems. Mol Cell. 2018;72:444-456.e7 pubmed publisher
Kong X, Kuilman T, Shahrabi A, Boshuizen J, Kemper K, Song J, et al. Cancer drug addiction is relayed by an ERK2-dependent phenotype switch. Nature. 2017;550:270-274 pubmed publisher
Luo C, Sheng J, Hu M, Haluska F, Cui R, Xu Z, et al. Loss of ARF sensitizes transgenic BRAFV600E mice to UV-induced melanoma via suppression of XPC. Cancer Res. 2013;73:4337-48 pubmed publisher
Takekoshi T, Fang L, Paragh G, Hwang S. CCR7-expressing B16 melanoma cells downregulate interferon-?-mediated inflammation and increase lymphangiogenesis in the tumor microenvironment. Oncogenesis. 2012;1:e9 pubmed publisher
Girotti M, Pedersen M, Sanchez Laorden B, Viros A, Turajlic S, Niculescu Duvaz D, et al. Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma. Cancer Discov. 2013;3:158-67 pubmed publisher
Nuccitelli R, Tran K, Lui K, Huynh J, Athos B, Kreis M, et al. Non-thermal nanoelectroablation of UV-induced murine melanomas stimulates an immune response. Pigment Cell Melanoma Res. 2012;25:618-29 pubmed publisher
Kim M, Lee J, Nehrbass U, Song R, Choi Y. Detection of melanoma using antibody-conjugated quantum dots in a coculture model for high-throughput screening system. Analyst. 2012;137:1440-5 pubmed publisher
Treviño Villarreal J, Cotanche D, Sepúlveda R, Bortoni M, Manneberg O, Udagawa T, et al. Host-derived pericytes and Sca-1+ cells predominate in the MART-1- stroma fraction of experimentally induced melanoma. J Histochem Cytochem. 2011;59:1060-75 pubmed publisher
Toh B, Wang X, Keeble J, Sim W, Khoo K, Wong W, et al. Mesenchymal transition and dissemination of cancer cells is driven by myeloid-derived suppressor cells infiltrating the primary tumor. PLoS Biol. 2011;9:e1001162 pubmed publisher
Lee S, Kim H, Jin Y, Choi A, Ryter S. Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis. Autophagy. 2011;7:829-39 pubmed
VanBrocklin M, Robinson J, Lastwika K, Khoury J, Holmen S. Targeted delivery of NRASQ61R and Cre-recombinase to post-natal melanocytes induces melanoma in Ink4a/Arflox/lox mice. Pigment Cell Melanoma Res. 2010;23:531-41 pubmed publisher
Azarova A, Lyu Y, Lin C, Tsai Y, Lau J, Wang J, et al. Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies. Proc Natl Acad Sci U S A. 2007;104:11014-9 pubmed
Yamazaki F, Okamoto H, Matsumura Y, Tanaka K, Kunisada T, Horio T. Development of a new mouse model (xeroderma pigmentosum a-deficient, stem cell factor-transgenic) of ultraviolet B-induced melanoma. J Invest Dermatol. 2005;125:521-5 pubmed
product information
CatalogNumber :
ab732
ItemName :
Anti-Melanoma antibody [HMB45 + M2-7C10 + M2-9E3]
Category :
Antibody
Host :
Mouse
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
HMB45 + M2-7C10 + M2-9E3
Size :
250 µl
SpeciesSummary :
Hu, Ms
Application Summary :
Flow Cyt, IHC-Fr, IHC-P
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
Stefan.Pritchard@abcam.com, eCommerce@abcam.com, Vicky.Yang@abcam.com
https://www.abcam.com
888-7722226
headquarters: UK