This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-Cyclin B1 antibody [V152]
catalog :
ab72
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
V152
reactivity :
human, mouse
application :
western blot, immunohistochemistry
citations: 46
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:500; loading ...; fig s2a
Daldello E, Luong X, Yang C, Kuhn J, Conti M. Cyclin B2 is required for progression through meiosis in mouse oocytes. Development. 2019;146: pubmed publisher
  • western blot; human; loading ...; fig 2d
Wang L, Wang J, Jin T, Zhou Y, Chen Q. FoxG1 facilitates proliferation and inhibits differentiation by downregulating FoxO/Smad signaling in glioblastoma. Biochem Biophys Res Commun. 2018;504:46-53 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6a
Aviner R, Hofmann S, Elman T, Shenoy A, Geiger T, Elkon R, et al. Proteomic analysis of polyribosomes identifies splicing factors as potential regulators of translation during mitosis. Nucleic Acids Res. 2017;45:5945-5957 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 6a
Yamada M, Egli D. Genome Transfer Prevents Fragmentation and Restores Developmental Potential of Developmentally Compromised Postovulatory Aged Mouse Oocytes. Stem Cell Reports. 2017;8:576-588 pubmed publisher
  • western blot; human; 1:1000; fig s3b
Kotsantis P, Silva L, Irmscher S, Jones R, Folkes L, Gromak N, et al. Increased global transcription activity as a mechanism of replication stress in cancer. Nat Commun. 2016;7:13087 pubmed publisher
  • western blot; human; 1:1000
Marthandan S, Baumgart M, Priebe S, Groth M, Schaer J, Kaether C, et al. Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq. PLoS ONE. 2016;11:e0154531 pubmed publisher
  • western blot; human; 1:1500; fig s11
Aviner R, Shenoy A, Elroy Stein O, Geiger T. Uncovering Hidden Layers of Cell Cycle Regulation through Integrative Multi-omic Analysis. PLoS Genet. 2015;11:e1005554 pubmed publisher
  • western blot; human; 1:1000; fig 5
Marthandan S, Priebe S, Baumgart M, Groth M, Cellerino A, Guthke R, et al. Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts. Biomed Res Int. 2015;2015:731938 pubmed publisher
  • western blot; human
Penas C, Ramachandran V, Simanski S, Lee C, Madoux F, Rahaim R, et al. Casein kinase 1?-dependent Wee1 protein degradation. J Biol Chem. 2014;289:18893-903 pubmed publisher
  • western blot; mouse; 1:500; fig 5
Holt J, Tran S, Stewart J, Minahan K, Garcia Higuera I, Moreno S, et al. The APC/C activator FZR1 coordinates the timing of meiotic resumption during prophase I arrest in mammalian oocytes. Development. 2011;138:905-13 pubmed publisher
Xiong Y, Zhang L, Wang T. Phosphorylation of BMK1 induces prostatic carcinoma cell proliferation by promoting entry into the S phase of the cell cycle. Oncol Lett. 2016;11:99-104 pubmed
Penas C, Mishra J, Wood S, Schürer S, Roush W, Ayad N. GSK3 inhibitors stabilize Wee1 and reduce cerebellar granule cell progenitor proliferation. Cell Cycle. 2015;14:417-24 pubmed publisher
Nabti I, Marangos P, Bormann J, Kudo N, Carroll J. Dual-mode regulation of the APC/C by CDK1 and MAPK controls meiosis I progression and fidelity. J Cell Biol. 2014;204:891-900 pubmed publisher
Kumar S, Mokhtari R, Oliveira I, Islam S, Toledo S, Yeger H, et al. Tumor dynamics in response to antiangiogenic therapy with oral metronomic topotecan and pazopanib in neuroblastoma xenografts. Transl Oncol. 2013;6:493-503 pubmed
Zhou L, Yang Y, Zhang J, Guo X, Bi Y, Li X, et al. The role of RING box protein 1 in mouse oocyte meiotic maturation. PLoS ONE. 2013;8:e68964 pubmed publisher
Holt J, Lane S, Jennings P, Garcia Higuera I, Moreno S, Jones K. APC(FZR1) prevents nondisjunction in mouse oocytes by controlling meiotic spindle assembly timing. Mol Biol Cell. 2012;23:3970-81 pubmed publisher
Shin J, Lee C, Lee K, Lee J, Lee K, Kim K, et al. Prognostic significance of ATM and cyclin B1 in pancreatic neuroendocrine tumor. Tumour Biol. 2012;33:1645-51 pubmed publisher
Yang C, Wei Y, Qi S, Chen L, Zhang Q, Ma J, et al. The G protein coupled receptor 3 is involved in cAMP and cGMP signaling and maintenance of meiotic arrest in porcine oocytes. PLoS ONE. 2012;7:e38807 pubmed publisher
Hu C, Ozlu N, Coughlin M, Steen J, Mitchison T. Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis. Mol Biol Cell. 2012;23:2702-11 pubmed publisher
Lane S, Yun Y, Jones K. Timing of anaphase-promoting complex activation in mouse oocytes is predicted by microtubule-kinetochore attachment but not by bivalent alignment or tension. Development. 2012;139:1947-55 pubmed publisher
Law P, Ching A, Chan A, Wong Q, Wong C, To K, et al. MiR-145 modulates multiple components of the insulin-like growth factor pathway in hepatocellular carcinoma. Carcinogenesis. 2012;33:1134-41 pubmed publisher
Bernhardt M, Kong B, Kim A, O Halloran T, Woodruff T. A zinc-dependent mechanism regulates meiotic progression in mammalian oocytes. Biol Reprod. 2012;86:114 pubmed publisher
Lu Y, Lou Y, Peng Q, Nghiem P, Conney A. Caffeine decreases phospho-Chk1 (Ser317) and increases mitotic cells with cyclin B1 and caspase 3 in tumors from UVB-treated mice. Cancer Prev Res (Phila). 2011;4:1118-25 pubmed publisher
Chang H, Jennings P, Stewart J, Verrills N, Jones K. Essential role of protein phosphatase 2A in metaphase II arrest and activation of mouse eggs shown by okadaic acid, dominant negative protein phosphatase 2A, and FTY720. J Biol Chem. 2011;286:14705-12 pubmed publisher
Shen W, Ahmad F, Hockman S, Ma J, Omi H, Raghavachari N, et al. Female infertility in PDE3A(-/-) mice: polo-like kinase 1 (Plk1) may be a target of protein kinase A (PKA) and involved in meiotic arrest of oocytes from PDE3A(-/-) mice. Cell Cycle. 2010;9:4720-34 pubmed
Bernhardt M, Kim A, O Halloran T, Woodruff T. Zinc requirement during meiosis I-meiosis II transition in mouse oocytes is independent of the MOS-MAPK pathway. Biol Reprod. 2011;84:526-36 pubmed publisher
Ciciarello M, Roscioli E, Di Fiore B, Di Francesco L, Sobrero F, Bernard D, et al. Nuclear reformation after mitosis requires downregulation of the Ran GTPase effector RanBP1 in mammalian cells. Chromosoma. 2010;119:651-68 pubmed publisher
Holt J, Weaver J, Jones K. Spatial regulation of APCCdh1-induced cyclin B1 degradation maintains G2 arrest in mouse oocytes. Development. 2010;137:1297-304 pubmed publisher
Gurden M, Holland A, van Zon W, Tighe A, Vergnolle M, Andres D, et al. Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F. J Cell Sci. 2010;123:321-30 pubmed publisher
Lou Y, Peng Q, Nolan B, Wagner G, LU Y. Oral administration of caffeine during voluntary exercise markedly decreases tissue fat and stimulates apoptosis and cyclin B1 in UVB-treated skin of hairless p53-knockout mice. Carcinogenesis. 2010;31:671-8 pubmed publisher
Cheng P, Li Y, Yang L, Wen Y, Shi W, Mao Y, et al. Hepatitis B virus X protein (HBx) induces G2/M arrest and apoptosis through sustained activation of cyclin B1-CDK1 kinase. Oncol Rep. 2009;22:1101-7 pubmed
Roa W, Zhang X, Guo L, Shaw A, Hu X, Xiong Y, et al. Gold nanoparticle sensitize radiotherapy of prostate cancer cells by regulation of the cell cycle. Nanotechnology. 2009;20:375101 pubmed publisher
Schindler K, Schultz R. CDC14B acts through FZR1 (CDH1) to prevent meiotic maturation of mouse oocytes. Biol Reprod. 2009;80:795-803 pubmed publisher
Nabti I, Reis A, Levasseur M, Stemmann O, Jones K. Securin and not CDK1/cyclin B1 regulates sister chromatid disjunction during meiosis II in mouse eggs. Dev Biol. 2008;321:379-86 pubmed publisher
Gisselsson D, Håkanson U, Stoller P, Marti D, Jin Y, Rosengren A, et al. When the genome plays dice: circumvention of the spindle assembly checkpoint and near-random chromosome segregation in multipolar cancer cell mitoses. PLoS ONE. 2008;3:e1871 pubmed publisher
Lu Y, Lou Y, Peng Q, Xie J, Nghiem P, Conney A. Effect of caffeine on the ATR/Chk1 pathway in the epidermis of UVB-irradiated mice. Cancer Res. 2008;68:2523-9 pubmed publisher
Marangos P, Carroll J. Securin regulates entry into M-phase by modulating the stability of cyclin B. Nat Cell Biol. 2008;10:445-51 pubmed publisher
Hämmerle B, Elizalde C, Tejedor F. The spatio-temporal and subcellular expression of the candidate Down syndrome gene Mnb/Dyrk1A in the developing mouse brain suggests distinct sequential roles in neuronal development. Eur J Neurosci. 2008;27:1061-74 pubmed publisher
Hämmerle B, Tejedor F. A novel function of DELTA-NOTCH signalling mediates the transition from proliferation to neurogenesis in neural progenitor cells. PLoS ONE. 2007;2:e1169 pubmed
Reis A, Madgwick S, Chang H, Nabti I, Levasseur M, Jones K. Prometaphase APCcdh1 activity prevents non-disjunction in mammalian oocytes. Nat Cell Biol. 2007;9:1192-8 pubmed
Hochegger H, Dejsuphong D, Sonoda E, Saberi A, Rajendra E, Kirk J, et al. An essential role for Cdk1 in S phase control is revealed via chemical genetics in vertebrate cells. J Cell Biol. 2007;178:257-68 pubmed
Hu D, Valentine M, Kidd V, Lahti J. CDK11(p58) is required for the maintenance of sister chromatid cohesion. J Cell Sci. 2007;120:2424-34 pubmed
Diaz Martinez L, Giménez Abián J, Clarke D. Cohesin is dispensable for centromere cohesion in human cells. PLoS ONE. 2007;2:e318 pubmed
Diaz Martinez L, Giménez Abián J, Clarke D. Regulation of centromeric cohesion by sororin independently of the APC/C. Cell Cycle. 2007;6:714-24 pubmed
Madgwick S, Hansen D, Levasseur M, Jackson P, Jones K. Mouse Emi2 is required to enter meiosis II by reestablishing cyclin B1 during interkinesis. J Cell Biol. 2006;174:791-801 pubmed
Giménez Abián J, Diaz Martinez L, Wirth K, Andrews C, Giménez Martín G, Clarke D. Regulated separation of sister centromeres depends on the spindle assembly checkpoint but not on the anaphase promoting complex/cyclosome. Cell Cycle. 2005;4:1561-75 pubmed
product information
CatalogNumber :
ab72
ItemName :
Anti-Cyclin B1 antibody [V152]
Product Type :
Primary Antibodies
Host Species :
Mouse
Clonality :
Monoclonal
Conjugate :
Not Conjugated
Antigen Modification :
No Modifications
Clone Name :
V152
Size :
100 µg
SpeciesSummary :
Hu, Ms
Uses :
Flow Cyt, ICC/IF, IHC (PFA fixed), IHC-FoFr, IHC-Fr, IHC-P, WB
Size Note :
Other sizes available: 100 µl
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK