This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-HDAC3 antibody - ChIP Grade
catalog :
ab7030
quantity :
25 µl
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section, ChIP-Seq, dot blot
citations: 23
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:2000; loading ...
Xu S, Tao H, Cao W, Cao L, Lin Y, Zhao S, et al. Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis. Signal Transduct Target Ther. 2021;6:54 pubmed publisher
  • ChIP-Seq; mouse; ; loading ...; fig s11a
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig s3c
  • chromatin immunoprecipitation; mouse; ; loading ...; fig 2i
  • immunoprecipitation; mouse; ; loading ...; fig 2e
  • western blot; mouse; loading ...; fig 2c
Kuang Z, Wang Y, Li Y, Ye C, Ruhn K, Behrendt C, et al. The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3. Science. 2019;365:1428-1434 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig s4b
  • western blot; human; 1:100; loading ...; fig 3a
Lino Cardenas C, Kessinger C, Cheng Y, MacDonald C, Macgillivray T, Ghoshhajra B, et al. An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm. Nat Commun. 2018;9:1009 pubmed publisher
  • chromatin immunoprecipitation; mouse; 1:50; loading ...; fig 4D
  • immunoprecipitation; mouse; 1:50; loading ...; fig 4C
  • western blot; mouse; 1:1000; loading ...; fig 4C
Chakraborty K, Raundhal M, Chen B, Morse C, Tyurina Y, Khare A, et al. The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia. Nat Commun. 2017;8:13944 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 3i
Liu L, Guan H, Li Y, Ying Z, Wu J, Zhu X, et al. Astrocyte Elevated Gene 1 Interacts with Acetyltransferase p300 and c-Jun To Promote Tumor Aggressiveness. Mol Cell Biol. 2017;37: pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig s1c
Phelps M, Bailey J, Vleeshouwer Neumann T, Chen E. CRISPR screen identifies the NCOR/HDAC3 complex as a major suppressor of differentiation in rhabdomyosarcoma. Proc Natl Acad Sci U S A. 2016;113:15090-15095 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5d
Chen W, Gao L, Wang J, Wang Y, Dong Z, Zhao J, et al. Conditional ablation of HDAC3 in islet beta cells results in glucose intolerance and enhanced susceptibility to STZ-induced diabetes. Oncotarget. 2016;7:57485-57497 pubmed publisher
  • chromatin immunoprecipitation; mouse; fig S5f
Nott A, Cheng J, Gao F, Lin Y, Gjoneska E, Ko T, et al. Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior. Nat Neurosci. 2016;19:1497-1505 pubmed publisher
  • chromatin immunoprecipitation; mouse; fig 1
Rando G, Tan C, Khaled N, Montagner A, Leuenberger N, Bertrand Michel J, et al. Glucocorticoid receptor-PPAR? axis in fetal mouse liver prepares neonates for milk lipid catabolism. elife. 2016;5: pubmed publisher
  • chromatin immunoprecipitation; human; fig 2
  • western blot; human; 1:2000; fig 7
Martínez Iglesias O, Alonso Merino E, Gómez Rey S, Velasco Martín J, Martín Orozco R, Luengo E, et al. Autoregulatory loop of nuclear corepressor 1 expression controls invasion, tumor growth, and metastasis. Proc Natl Acad Sci U S A. 2016;113:E328-37 pubmed publisher
Pedone E, Postiglione L, Aulicino F, Rocca D, Montes Olivas S, Khazim M, et al. A tunable dual-input system for on-demand dynamic gene expression regulation. Nat Commun. 2019;10:4481 pubmed publisher
Park S, Yoo H, Seol J, Rhee K. HDAC3 and HDAC8 are required for cilia assembly and elongation. Biol Open. 2019;8: pubmed publisher
Zhou W, He Y, Rehman A, Kong Y, Hong S, Ding G, et al. Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection. Nat Neurosci. 2019;22:205-217 pubmed publisher
Choi S, Jeong H, Kim H, Choi D, Cho S, Seong J, et al. Skeletal muscle-specific Prmt1 deletion causes muscle atrophy via deregulation of the PRMT6-FOXO3 axis. Autophagy. 2019;15:1069-1081 pubmed publisher
Rosenberg L, Cattin A, Fontana X, Harford Wright E, Burden J, White I, et al. HDAC3 Regulates the Transition to the Homeostatic Myelinating Schwann Cell State. Cell Rep. 2018;25:2755-2765.e5 pubmed publisher
Dyar K, Hubert M, Mir A, Ciciliot S, Lutter D, Greulich F, et al. Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock. PLoS Biol. 2018;16:e2005886 pubmed publisher
Zhao Y, He J, Yang L, Luo Q, Liu Z. Histone Deacetylase-3 Modification of MicroRNA-31 Promotes Cell Proliferation and Aerobic Glycolysis in Breast Cancer and Is Predictive of Poor Prognosis. J Breast Cancer. 2018;21:112-123 pubmed publisher
Zupkovitz G, Lagger S, Martin D, Steiner M, Hagelkruys A, Seiser C, et al. Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri. Histochem Cell Biol. 2018;150:255-269 pubmed publisher
Czimmerer Z, Dániel B, Horvath A, Rückerl D, Nagy G, Kiss M, et al. The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages. Immunity. 2018;48:75-90.e6 pubmed publisher
Poleshko A, Shah P, Gupta M, Babu A, Morley M, Manderfield L, et al. Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction. Cell. 2017;171:573-587.e14 pubmed publisher
Tavera Mendoza L, Westerling T, Libby E, Marusyk A, Cato L, Cassani R, et al. Vitamin D receptor regulates autophagy in the normal mammary gland and in luminal breast cancer cells. Proc Natl Acad Sci U S A. 2017;114:E2186-E2194 pubmed publisher
Zhang Y, Geng C, Liu X, Li M, Gao M, Liu X, et al. Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1. Mol Metab. 2017;6:138-147 pubmed publisher
Huichalaf C, Micheloni S, Ferri G, Caccia R, Gabellini D. DNA methylation analysis of the macrosatellite repeat associated with FSHD muscular dystrophy at single nucleotide level. PLoS ONE. 2014;9:e115278 pubmed publisher
product information
CatalogNumber :
ab7030
ItemName :
Anti-HDAC3 antibody - ChIP Grade
Product Type :
Primary Antibodies
Host Species :
Rabbit
Clonality :
Polyclonal
Conjugate :
Not Conjugated
Antigen Modification :
No Modifications
Size :
25 µl
SpeciesSummary :
Hu, Ms
Uses :
ChIP, Dot, ICC/IF, IHC-P, IP, WB
Size Note :
Other sizes available: 50 µl
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK