This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-SAMHD1 antibody
catalog :
ab67820
quantity :
50 µg
clonality :
polyclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunocytochemistry
citations: 7
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 4d
  • western blot; human; loading ...; fig 5b
Hu J, Gao Q, Yang Y, Xia J, Zhang W, Chen Y, et al. Hexosamine biosynthetic pathway promotes the antiviral activity of SAMHD1 by enhancing O-GlcNAc transferase-mediated protein O-GlcNAcylation. Theranostics. 2021;11:805-823 pubmed publisher
  • western blot; human; fig 3g
Mlcochova P, Sutherland K, Watters S, Bertoli C, de Bruin R, Rehwinkel J, et al. A G1-like state allows HIV-1 to bypass SAMHD1 restriction in macrophages. EMBO J. 2017;36:604-616 pubmed publisher
Francis A, Marin M, Singh P, Achuthan V, Prellberg M, Palermino Rowland K, et al. HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains. Nat Commun. 2020;11:3505 pubmed publisher
Antonucci J, Kim S, St Gelais C, Bonifati S, Li T, Buzovetsky O, et al. SAMHD1 Impairs HIV-1 Gene Expression and Negatively Modulates Reactivation of Viral Latency in CD4+ T Cells. J Virol. 2018;92: pubmed publisher
Mlcochova P, Caswell S, Taylor I, Towers G, Gupta R. DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of macrophages. EMBO J. 2018;37:50-62 pubmed publisher
Valle Casuso J, Allouch A, David A, Lenzi G, Studdard L, Barré Sinoussi F, et al. p21 Restricts HIV-1 in Monocyte-Derived Dendritic Cells through the Reduction of Deoxynucleoside Triphosphate Biosynthesis and Regulation of SAMHD1 Antiviral Activity. J Virol. 2017;91: pubmed publisher
Wang H, Guo H, Su J, Rui Y, Zheng W, Gao W, et al. Inhibition of Vpx-Mediated SAMHD1 and Vpr-Mediated Host Helicase Transcription Factor Degradation by Selective Disruption of Viral CRL4 (DCAF1) E3 Ubiquitin Ligase Assembly. J Virol. 2017;91: pubmed publisher
product information
CatalogNumber :
ab67820
ItemName :
Anti-SAMHD1 antibody
Product Type :
Primary Antibodies
Host Species :
Mouse
Clonality :
Polyclonal
Conjugate :
Not Conjugated
Antigen Modification :
No Modifications
Size :
50 µg
SpeciesSummary :
Hu
Uses :
ICC/IF, WB
Size Note :
Other sizes available: 50 µl
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK