This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-DNA/RNA Damage antibody [15A3]
catalog :
ab62623
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
15A3
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 22
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 5b
Ramos H, Bogdanov P, Huerta J, De xe0 s Just A, Hern xe1 ndez C, Sim xf3 R. Antioxidant Effects of DPP-4 Inhibitors in Early Stages of Experimental Diabetic Retinopathy. Antioxidants (Basel). 2022;11: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:300; loading ...; fig 5b
Ding R, Li H, Liu Y, Ou W, Zhang X, Chai H, et al. Activating cGAS-STING axis contributes to neuroinflammation in CVST mouse model and induces inflammasome activation and microglia pyroptosis. J Neuroinflammation. 2022;19:137 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 3d
Saha J, Bae J, Wang S, Lu H, Chappell L, Gopal P, et al. Ablating putative Ku70 phosphorylation sites results in defective DNA damage repair and spontaneous induction of hepatocellular carcinoma. Nucleic Acids Res. 2021;49:9836-9850 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 4a
Liang X, Yan Z, Ma W, Qian Y, Zou X, Cui Y, et al. Peroxiredoxin 4 protects against ovarian ageing by ameliorating D-galactose-induced oxidative damage in mice. Cell Death Dis. 2020;11:1053 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 4a
Sun Q, Chen J, Xu L, Kang J, Wu X, Ren Y, et al. MUTYH Deficiency Is Associated with Attenuated Pulmonary Fibrosis in a Bleomycin-Induced Model. Oxid Med Cell Longev. 2020;2020:4828256 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 5s1c
Kopp F, Elguindy M, Yalvac M, Zhang H, Chen B, Gillett F, et al. PUMILIO hyperactivity drives premature aging of Norad-deficient mice. elife. 2019;8: pubmed publisher
  • immunohistochemistry; human; 1:1000; loading ...; fig 4b
Cabezas R, Vega Vela N, González Sanmiguel J, Gonzalez J, Esquinas P, Echeverria V, et al. PDGF-BB Preserves Mitochondrial Morphology, Attenuates ROS Production, and Upregulates Neuroglobin in an Astrocytic Model Under Rotenone Insult. Mol Neurobiol. 2018;55:3085-3095 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 2b
Wang H, Chen T, Weng C, Yang C, Tang M. Acrolein preferentially damages nucleolus eliciting ribosomal stress and apoptosis in human cancer cells. Oncotarget. 2016;7:80450-80464 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 2c
Li B, Guo W, Hong L, Liu Y, Liu C, Hong S, et al. Role of mechanical strain-activated PI3K/Akt signaling pathway in pelvic organ prolapse. Mol Med Rep. 2016;14:243-53 pubmed publisher
  • immunocytochemistry; human; 1:250; fig 2
Lood C, Blanco L, Purmalek M, Carmona Rivera C, De Ravin S, Smith C, et al. Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease. Nat Med. 2016;22:146-53 pubmed publisher
Ma D, Hwang J, Noh K, Oh S, Kim K, Shin Y. Role of NADPH Oxidase 4 in Corneal Endothelial Cells Is Mediated by Endoplasmic Reticulum Stress and Autophagy. Antioxidants (Basel). 2023;12: pubmed publisher
Li C, Zhao Z, Luo Y, Ning T, LIU P, Chen Q, et al. Macrophage-Disguised Manganese Dioxide Nanoparticles for Neuroprotection by Reducing Oxidative Stress and Modulating Inflammatory Microenvironment in Acute Ischemic Stroke. Adv Sci (Weinh). 2021;8:e2101526 pubmed publisher
Liu H, Wang T, Hsu Y, Chou C, Huang K, Hsu C, et al. Nanoparticulated Honokiol Mitigates Cisplatin-Induced Chronic Kidney Injury by Maintaining Mitochondria Antioxidant Capacity and Reducing Caspase 3-Associated Cellular Apoptosis. Antioxidants (Basel). 2019;8: pubmed publisher
Rojas Morales P, Tapia E, León Contreras J, González Reyes S, Jiménez Osorio A, Trujillo J, et al. Mechanisms of Fasting-Mediated Protection against Renal Injury and Fibrosis Development after Ischemic Acute Kidney Injury. Biomolecules. 2019;9: pubmed publisher
Rockfield S, Kee Y, Nanjundan M. Chronic iron exposure and c-Myc/H-ras-mediated transformation in fallopian tube cells alter the expression of EVI1, amplified at 3q26.2 in ovarian cancer. Oncogenesis. 2019;8:46 pubmed publisher
Tian X, Wang F, Luo Y, Ma S, Zhang N, Sun Y, et al. Protective Role of Nuclear Factor-Erythroid 2-Related Factor 2 Against Radiation-Induced Lung Injury and Inflammation. Front Oncol. 2018;8:542 pubmed publisher
Fang G, Hong L, Liu C, Yang Q, Zhang Q, Li Y, et al. Oxidative status of cardinal ligament in pelvic organ prolapse. Exp Ther Med. 2018;16:3293-3302 pubmed publisher
Giacci M, Bartlett C, Smith N, Iyer K, Toomey L, Jiang H, et al. Oligodendroglia Are Particularly Vulnerable to Oxidative Damage after Neurotrauma In Vivo. J Neurosci. 2018;38:6491-6504 pubmed publisher
Zhang J, Lai Z, Shi L, Tian Y, Luo A, Xu Z, et al. Repeated superovulation increases the risk of osteoporosis and cardiovascular diseases by accelerating ovarian aging in mice. Aging (Albany NY). 2018;10:1089-1102 pubmed publisher
Duan J, Zhang H, Li S, Wang X, Yang H, Jiao S, et al. The role of miR-485-5p/NUDT1 axis in gastric cancer. Cancer Cell Int. 2017;17:92 pubmed publisher
Prakash Bangalore M, Adhikarla S, Mukherjee O, Panicker M. Genotoxic Effects of Culture Media on Human Pluripotent Stem Cells. Sci Rep. 2017;7:42222 pubmed publisher
Liu C, Yang Q, Fang G, Li B, Wu D, Guo W, et al. Collagen metabolic disorder induced by oxidative stress in human uterosacral ligament‑derived fibroblasts: A possible pathophysiological mechanism in pelvic organ prolapse. Mol Med Rep. 2016;13:2999-3008 pubmed publisher
product information
CatalogNumber :
ab62623
ItemName :
Anti-DNA/RNA Damage antibody [15A3]
Category :
Antibody
Host :
Mouse
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
15A3
Size :
100 µg
Application Summary :
ELISA, ICC/IF, IHC-FoFr, IHC-Fr, IHC-P
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
Stefan.Pritchard@abcam.com, eCommerce@abcam.com, Vicky.Yang@abcam.com
https://www.abcam.com
888-7722226
headquarters: UK