This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Ascent Scientific
product type :
antibody
product name :
PARP antibody
catalog :
ab6079
quantity :
1 ml
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation
citations: 24
Published Application/Species/DilutionReference
  • western blot; mouse
Okada T, Nitta T, Kaji K, Takashima A, Oda H, Tamehiro N, et al. Differential function of Themis CABIT domains during T cell development. PLoS ONE. 2014;9:e89115 pubmed publisher
  • chromatin immunoprecipitation; human
Lodhi N, Kossenkov A, Tulin A. Bookmarking promoters in mitotic chromatin: poly(ADP-ribose)polymerase-1 as an epigenetic mark. Nucleic Acids Res. 2014;42:7028-38 pubmed publisher
Xu Z, Zhang L, Zhang W, Meng D, Zhang H, Jiang Y, et al. SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner. Cell Cycle. 2015;14:269-76 pubmed publisher
Gungor-Ordueri N, Sahin Z, Sahin P, Celik-Ozenci C. The expression pattern of PARP-1 and PARP-2 in the developing and adult mouse testis. Acta Histochem. 2014;116:958-64 pubmed publisher
Csonka T, Murnyák B, Szepesi R, Kurucz A, Klekner A, Hortobagyi T. Poly(ADP-ribose) polymerase-1 (PARP1) and p53 labelling index correlates with tumour grade in meningiomas. Folia Neuropathol. 2014;52:111-20 pubmed
Donizy P, Pietrzyk G, Halon A, Kozyra C, Gansukh T, Lage H, et al. Nuclear-cytoplasmic PARP-1 expression as an unfavorable prognostic marker in lymph node‑negative early breast cancer: 15-year follow-up. Oncol Rep. 2014;31:1777-87 pubmed publisher
Chang V, Yang D, Lin H, Pearce G, Ryan C, Chen Y. IbACP, a sixteen-amino-acid peptide isolated from Ipomoea batatas leaves, induces carcinoma cell apoptosis. Peptides. 2013;47:148-56 pubmed publisher
Loganathan R, Selvaduray K, Nesaretnam K, Radhakrishnan A. Tocotrienols promote apoptosis in human breast cancer cells by inducing poly(ADP-ribose) polymerase cleavage and inhibiting nuclear factor kappa-B activity. Cell Prolif. 2013;46:203-13 pubmed publisher
Zucca E, Bertoletti F, Wimmer U, Ferrari E, Mazzini G, Khoronenkova S, et al. Silencing of human DNA polymerase λ causes replication stress and is synthetically lethal with an impaired S phase checkpoint. Nucleic Acids Res. 2013;41:229-41 pubmed publisher
Lu Y, Luo Y, He Z, Chen J, Yan B, Wang Y, et al. Hydroxysafflor yellow A ameliorates homocysteine-induced Alzheimer-like pathologic dysfunction and memory/synaptic disorder. Rejuvenation Res. 2013;16:446-52 pubmed publisher
Spirkoski J, Melo F, Grujic M, Calounova G, Lundequist A, Wernersson S, et al. Mast cell apoptosis induced by siramesine, a sigma-2 receptor agonist. Biochem Pharmacol. 2012;84:1671-80 pubmed publisher
Zhong W, Sit W, Wan J, Yu A. Sonoporation induces apoptosis and cell cycle arrest in human promyelocytic leukemia cells. Ultrasound Med Biol. 2011;37:2149-59 pubmed publisher
Brockschmidt A, Chung B, Weber S, Fischer D, Kolatsi-Joannou M, Christ L, et al. CHD1L: a new candidate gene for congenital anomalies of the kidneys and urinary tract (CAKUT). Nephrol Dial Transplant. 2012;27:2355-64 pubmed publisher
Zhou L, Azfer A, Niu J, Graham S, Choudhury M, Adamski F, et al. Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction. Circ Res. 2006;98:1177-85 pubmed
Pardo M, Lang B, Yu L, Prosser H, Bradley A, Babu M, et al. An expanded Oct4 interaction network: implications for stem cell biology, development, and disease. Cell Stem Cell. 2010;6:382-95 pubmed publisher
Kleppa L, Mari P, Larsen E, Lien G, Godon C, Theil A, et al. Kinetics of endogenous mouse FEN1 in base excision repair. Nucleic Acids Res. 2012;40:9044-59 pubmed publisher
Tasatargil A, Tekcan M, Celik-Ozenci C, Ece Gungor N, Dalkiran B. Aldosterone-induced endothelial dysfunction of rat aorta: role of poly(ADP-ribose) activation. J Renin Angiotensin Aldosterone Syst. 2009;10:127-37 pubmed publisher
Yoo L, Hong S, Shin K, Kang S. PARP-1 regulates the expression of caspase-11. Biochem Biophys Res Commun. 2011;408:489-93 pubmed publisher
Podowski M, Calvi C, Cheadle C, Tuder R, Biswals S, Neptune E. Complex integration of matrix, oxidative stress, and apoptosis in genetic emphysema. Am J Pathol. 2009;175:84-96 pubmed publisher
Burgess H, Richardson W, Anderson R, Salaun C, Graham S, Gray N. Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs. J Cell Sci. 2011;124:3344-55 pubmed publisher
Mao Z, Hine C, Tian X, Van Meter M, Au M, Vaidya A, et al. SIRT6 promotes DNA repair under stress by activating PARP1. Science. 2011;332:1443-6 pubmed publisher
Mehrotra P, Ahel D, Ryan D, Weston R, Wiechens N, Kraehenbuehl R, et al. DNA repair factor APLF is a histone chaperone. Mol Cell. 2011;41:46-55 pubmed publisher
Mikula M, Gaj P, Dzwonek K, Rubel T, Karczmarski J, Paziewska A, et al. Comprehensive analysis of the palindromic motif TCTCGCGAGA: a regulatory element of the HNRNPK promoter. DNA Res. 2010;17:245-60 pubmed publisher
Tekcan M, Koksal I, Tasatargil A, Kutlu O, Gungör E, Celik-Ozenci C. Potential role of poly(ADP-ribose) polymerase activation in the pathogenesis of experimental left varicocele. J Androl. 2012;33:122-32 pubmed publisher
product information
Catalog Number :
ab6079
Product Name :
PARP antibody
Host Species :
Rabbit
Clonality :
polyclonal
Product Type :
Primary antibodies
Size :
1 ml
SwissProtID :
P09874
Isotype :
IgG
CrossReactivity :
Reacts with: Human, Mouse, Rat.
Application Summary :
ICC, ICC/IF, IHC-P, IP, WB
company information
Abcam
330 Cambridge Science Park
Cambridge
CB4 0FL UK
orders@abcam.com
44 (0)1223 696000

1 Kendall Square, Ste 341
Cambridge, MA 02139-1517
USA
us.orders@abcam.com
617 225 2272, 888-77-ABCAM (22226)

www.abcam.com
888-7722226
headquarters: UK