This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-MeCP2 antibody [Mec-168]
catalog :
ab50005
quantity :
100 µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Mec-168
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:2000; fig 1
Li R, Dong Q, Yuan X, Zeng X, Gao Y, Chiao C, et al. Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome. PLoS Genet. 2016;12:e1006129 pubmed publisher
  • immunohistochemistry; human; 1:500; fig 3
Williams A, White R, Siniard A, Corneveaux J, Huentelman M, Duch C. MECP2 impairs neuronal structure by regulating KIBRA. Neurobiol Dis. 2016;91:284-91 pubmed publisher
Dong Q, Liu Q, Li R, Wang A, Bu Q, Wang K, et al. Mechanism and consequence of abnormal calcium homeostasis in Rett syndrome astrocytes. elife. 2018;7: pubmed publisher
Deng J, Orsini C, Shimp K, Setlow B. MeCP2 Expression in a Rat Model of Risky Decision Making. Neuroscience. 2018;369:212-221 pubmed publisher
Bueno C, Tabares Seisdedos R, Moraleda J, Martinez S. Rett Syndrome Mutant Neural Cells Lacks MeCP2 Immunoreactive Bands. PLoS ONE. 2016;11:e0153262 pubmed publisher
Li H, Zhong X, Chau K, Santistevan N, Guo W, Kong G, et al. Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesis involving the Notch signalling pathway. Nat Commun. 2014;5:5601 pubmed publisher
Hess Homeier D, Fan C, Gupta T, Chiang A, Certel S. Astrocyte-specific regulation of hMeCP2 expression in Drosophila. Biol Open. 2014;3:1011-9 pubmed publisher
Reyes Aguirre L, Ferraro S, Quintero H, Sánchez Serrano S, Gomez Montalvo A, Lamas M. Glutamate-induced epigenetic and morphological changes allow rat Müller cell dedifferentiation but not further acquisition of a photoreceptor phenotype. Neuroscience. 2013;254:347-60 pubmed publisher
Vonhoff F, Williams A, Ryglewski S, Duch C. Drosophila as a model for MECP2 gain of function in neurons. PLoS ONE. 2012;7:e31835 pubmed publisher
Squillaro T, Alessio N, Cipollaro M, Melone M, Hayek G, Renieri A, et al. Reduced expression of MECP2 affects cell commitment and maintenance in neurons by triggering senescence: new perspective for Rett syndrome. Mol Biol Cell. 2012;23:1435-45 pubmed publisher
Vecsler M, Ben Zeev B, Nudelman I, Anikster Y, Simon A, Amariglio N, et al. Ex vivo treatment with a novel synthetic aminoglycoside NB54 in primary fibroblasts from Rett syndrome patients suppresses MECP2 nonsense mutations. PLoS ONE. 2011;6:e20733 pubmed publisher
Deng J, Rodriguiz R, Hutchinson A, Kim I, Wetsel W, West A. MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants. Nat Neurosci. 2010;13:1128-36 pubmed publisher
Lusardi T, Farr C, Faulkner C, Pignataro G, Yang T, Lan J, et al. Ischemic preconditioning regulates expression of microRNAs and a predicted target, MeCP2, in mouse cortex. J Cereb Blood Flow Metab. 2010;30:744-56 pubmed publisher
product information
CatalogNumber :
ab50005
ItemName :
Anti-MeCP2 antibody [Mec-168]
Category :
Antibody
Host :
Mouse
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
Mec-168
Size :
100 µl
SpeciesSummary :
Dm, Hu, Ms, Rat
Application Summary :
ELISA, ICC/IF, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK