This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-4 Hydroxynonenal antibody [HNEJ-2]
catalog :
ab48506
quantity :
50 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
HNEJ-2
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - free floating section
citations: 23
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 5a
Fang L, Wang W, Chen J, Zuo A, Gao H, Yan T, et al. Osthole Attenuates Bleomycin-Induced Pulmonary Fibrosis by Modulating NADPH Oxidase 4-Derived Oxidative Stress in Mice. Oxid Med Cell Longev. 2021;2021:3309944 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 5b
Wilson R, Drake J, Cui D, Lewellen B, Fisher C, Zhang M, et al. Mitochondrial protein S-nitrosation protects against ischemia reperfusion-induced denervation at neuromuscular junction in skeletal muscle. Free Radic Biol Med. 2018;117:180-190 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 7a
Song L, Yu A, Murray K, Cortopassi G. Bipolar cell reduction precedes retinal ganglion neuron loss in a complex 1 knockout mouse model. Brain Res. 2017;1657:232-244 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 7g
Kemp K, Cerminara N, Hares K, Redondo J, Cook A, Haynes H, et al. Cytokine therapy-mediated neuroprotection in a Friedreich's ataxia mouse model. Ann Neurol. 2017;81:212-226 pubmed publisher
  • immunocytochemistry; human; 1:50; fig 3h
Dugmonits K, Ferencz A, Zahorán S, Lázár R, Talapka P, Orvos H, et al. Elevated levels of macromolecular damage are correlated with increased nitric oxide synthase expression in erythrocytes isolated from twin neonates. Br J Haematol. 2016;174:932-41 pubmed publisher
Vokshi B, Davidson G, Tawanaie Pour Sedehi N, Helleux A, Rippinger M, Haller A, et al. SMARCB1 regulates a TFCP2L1-MYC transcriptional switch promoting renal medullary carcinoma transformation and ferroptosis resistance. Nat Commun. 2023;14:3034 pubmed publisher
Mishima E, Ito J, Wu Z, Nakamura T, Wahida A, Doll S, et al. A non-canonical vitamin K cycle is a potent ferroptosis suppressor. Nature. 2022;608:778-783 pubmed publisher
Skorokhod O, Barrera V, Mandili G, Costanza F, Valente E, Ulliers D, et al. Malaria Pigment Hemozoin Impairs GM-CSF Receptor Expression and Function by 4-Hydroxynonenal. Antioxidants (Basel). 2021;10: pubmed publisher
Vanhunsel S, Bergmans S, Beckers A, Etienne I, Van Houcke J, Seuntjens E, et al. The killifish visual system as an in vivo model to study brain aging and rejuvenation. NPJ Aging Mech Dis. 2021;7:22 pubmed publisher
Shi Y, Hou S. Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4. Mol Med Rep. 2021;24: pubmed publisher
Zahorán S, Szántó P, Bódi N, Bagyánszki M, Maléth J, Hegyi P, et al. Sustained Maternal Smoking Triggers Endothelial-Mediated Oxidative Stress in the Umbilical Cord Vessels, Resulting in Vascular Dysfunction. Antioxidants (Basel). 2021;10: pubmed publisher
Chen C, Chen J, Tao X, Fu M, Cheng B, Chen X. Activation of GPR30 with G1 inhibits oscillatory shear stress-induced adhesion of THP-1 monocytes to HAECs by increasing KLF2. Aging (Albany NY). 2021;13:11942-11953 pubmed publisher
Li Q, Xu Q, Tan J, Hu L, Ge C, Xu M. Carminic acid supplementation protects against fructose-induced kidney injury mainly through suppressing inflammation and oxidative stress via improving Nrf-2 signaling. Aging (Albany NY). 2021;13:10326-10353 pubmed publisher
Ma L, Zhang X, Yu K, Xu X, Chen T, Shi Y, et al. Targeting SLC3A2 subunit of system XC- is essential for m6A reader YTHDC2 to be an endogenous ferroptosis inducer in lung adenocarcinoma. Free Radic Biol Med. 2021;168:25-43 pubmed publisher
De Miranda B, Castro S, Rocha E, Bodle C, Johnson K, Greenamyre J. The industrial solvent trichloroethylene induces LRRK2 kinase activity and dopaminergic neurodegeneration in a rat model of Parkinson's disease. Neurobiol Dis. 2021;153:105312 pubmed publisher
De Logu F, Trevisan G, Marone I, Coppi E, Padilha Dalenogare D, Titiz M, et al. Oxidative stress mediates thalidomide-induced pain by targeting peripheral TRPA1 and central TRPV4. BMC Biol. 2020;18:197 pubmed publisher
Heden T, Johnson J, Ferrara P, Eshima H, Verkerke A, Wentzler E, et al. Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity. Sci Adv. 2019;5:eaax8352 pubmed publisher
Defourny J, Aghaie A, Perfettini I, Avan P, Delmaghani S, Petit C. Pejvakin-mediated pexophagy protects auditory hair cells against noise-induced damage. Proc Natl Acad Sci U S A. 2019;116:8010-8017 pubmed publisher
Maruyama T, Baba T, Maemoto Y, Hara Miyauchi C, Hasegawa Ogawa M, Okano H, et al. Loss of DDHD2, whose mutation causes spastic paraplegia, promotes reactive oxygen species generation and apoptosis. Cell Death Dis. 2018;9:797 pubmed publisher
Yang C, Demars K, Candelario Jalil E. Age-Dependent Decrease in Adropin is Associated with Reduced Levels of Endothelial Nitric Oxide Synthase and Increased Oxidative Stress in the Rat Brain. Aging Dis. 2018;9:322-330 pubmed publisher
Lee H, Lim S, Lee H, Yoo H, Kim H. Yuk-Mi-Jihwang-Tang, a Traditional Korean Multiple Herbal Formulae, Improves Hippocampal Memory on Scopolamine Injection-Induced Amnesia Model of C57BL/6 Mice. Evid Based Complement Alternat Med. 2018;2018:2821040 pubmed publisher
Gasparetto M, Pei S, Minhajuddin M, Khan N, Pollyea D, Myers J, et al. Targeted therapy for a subset of acute myeloid leukemias that lack expression of aldehyde dehydrogenase 1A1. Haematologica. 2017;102:1054-1065 pubmed publisher
Mohan K, Kecova H, Hernandez Merino E, Kardon R, Harper M. Retinal ganglion cell damage in an experimental rodent model of blast-mediated traumatic brain injury. Invest Ophthalmol Vis Sci. 2013;54:3440-50 pubmed publisher
product information
CatalogNumber :
ab48506
ItemName :
Anti-4 Hydroxynonenal antibody [HNEJ-2]
Category :
Antibody
Host :
Mouse
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
HNEJ-2
Size :
50 µg
Application Summary :
ELISA, Flow Cyt, IHC-FoFr, IHC-P, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
Stefan.Pritchard@abcam.com, eCommerce@abcam.com, Vicky.Yang@abcam.com
https://www.abcam.com
888-7722226
headquarters: UK