This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-4 Hydroxynonenal antibody
catalog :
ab46545
quantity :
100 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 106
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3d, 6g
  • immunohistochemistry; human; loading ...; fig 1e
  • western blot; human; loading ...; fig 1d
Tong J, Li D, Meng H, Sun D, Lan X, Ni M, et al. Targeting a novel inducible GPX4 alternative isoform to alleviate ferroptosis and treat metabolic-associated fatty liver disease. Acta Pharm Sin B. 2022;12:3650-3666 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 2a
Stancic A, Velickovic K, Markelic M, Grigorov I, Saksida T, Savić N, et al. Involvement of Ferroptosis in Diabetes-Induced Liver Pathology. Int J Mol Sci. 2022;23: pubmed publisher
  • western blot; mouse; loading ...; fig 1i
Zhuang A, Yang C, Liu Y, Tan Y, Bond S, Walker S, et al. SOD2 in skeletal muscle: New insights from an inducible deletion model. Redox Biol. 2021;47:102135 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 2b
Hou K, Shen J, Yan J, Zhai C, Zhang J, Pan J, et al. Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin. EBioMedicine. 2021;69:103456 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 6a, 6b, 6c, 6d
Anandhan A, Nguyen N, Syal A, Dreher L, Dodson M, Zhang D, et al. NRF2 Loss Accentuates Parkinsonian Pathology and Behavioral Dysfunction in Human α-Synuclein Overexpressing Mice. Aging Dis. 2021;12:964-982 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 3c
Wang L, Lavier J, Hua W, Wang Y, Gong L, Wei H, et al. High-Intensity Interval Training and Moderate-Intensity Continuous Training Attenuate Oxidative Damage and Promote Myokine Response in the Skeletal Muscle of ApoE KO Mice on High-Fat Diet. Antioxidants (Basel). 2021;10: pubmed publisher
  • western blot; mouse; 1:3000; loading ...; fig 7g
Wang Q, Bin C, Xue Q, Gao Q, Huang A, Wang K, et al. GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis. Cell Death Dis. 2021;12:426 pubmed publisher
  • western blot; mouse; 1:200; loading ...; fig 4b
Li S, Jiang B, Yu H, Song D. Regulation of PINX1 expression ameliorates lipopolysaccharide-induced lung injury and alleviates cell senescence during the convalescent phase through affecting the telomerase activity. Aging (Albany NY). 2021;13:10175-10186 pubmed publisher
  • western blot; mouse; 1:200; loading ...; fig 4b
Rudi W, Molitor M, Garlapati V, Finger S, Wild J, Munzel T, et al. ACE Inhibition Modulates Myeloid Hematopoiesis after Acute Myocardial Infarction and Reduces Cardiac and Vascular Inflammation in Ischemic Heart Failure. Antioxidants (Basel). 2021;10: pubmed publisher
  • western blot; mouse; 1:200; loading ...; fig 4b
Korovila I, Höhn A, Jung T, Grune T, Ott C. Reduced Liver Autophagy in High-Fat Diet Induced Liver Steatosis in New Zealand Obese Mice. Antioxidants (Basel). 2021;10: pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 5c
Cui W, Liu D, Gu W, Chu B. Peroxisome-driven ether-linked phospholipids biosynthesis is essential for ferroptosis. Cell Death Differ. 2021;28:2536-2551 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 1a
Grimley E, Cole A, Luong T, McGonigal S, Sinno S, Yang D, et al. Aldehyde dehydrogenase inhibitors promote DNA damage in ovarian cancer and synergize with ATM/ATR inhibitors. Theranostics. 2021;11:3540-3551 pubmed publisher
  • immunohistochemistry; mouse
Zhang Y, Yang Y, Xu M, Zheng J, Xu Y, Chen G, et al. The Dual Effects of Reactive Oxygen Species on the Mandibular Alveolar Bone Formation in SOD1 Knockout Mice: Promotion or Inhibition. Oxid Med Cell Longev. 2021;2021:8847140 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3a
Lyu L, Chen J, Wang W, Yan T, Lin J, Gao H, et al. Scoparone alleviates Ang II-induced pathological myocardial hypertrophy in mice by inhibiting oxidative stress. J Cell Mol Med. 2021;25:3136-3148 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 5g
  • western blot; mouse; fig 5h
Luo X, Gong H, Gao H, Wu Y, Sun W, Li Z, et al. Oxygenated phosphatidylethanolamine navigates phagocytosis of ferroptotic cells by interacting with TLR2. Cell Death Differ. 2021;: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 4a
Liang X, Yan Z, Ma W, Qian Y, Zou X, Cui Y, et al. Peroxiredoxin 4 protects against ovarian ageing by ameliorating D-galactose-induced oxidative damage in mice. Cell Death Dis. 2020;11:1053 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 3k
Ma L, Chen T, Zhang X, Miao Y, Tian X, Yu K, et al. The m6A reader YTHDC2 inhibits lung adenocarcinoma tumorigenesis by suppressing SLC7A11-dependent antioxidant function. Redox Biol. 2021;38:101801 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 6c
Zhao J, Li G, Zhao X, Lin X, Gao Y, Raimundo N, et al. Down-regulation of AMPK signaling pathway rescues hearing loss in TFB1 transgenic mice and delays age-related hearing loss. Aging (Albany NY). 2020;12:5590-5611 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5a
Arc Chagnaud C, Py G, Fovet T, Roumanille R, Demangel R, Pagano A, et al. Evaluation of an Antioxidant and Anti-inflammatory Cocktail Against Human Hypoactivity-Induced Skeletal Muscle Deconditioning. Front Physiol. 2020;11:71 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 8c
Zhuang K, Zuo Y, Sherchan P, Wang J, Yan X, Liu F. Hydrogen Inhalation Attenuates Oxidative Stress Related Endothelial Cells Injury After Subarachnoid Hemorrhage in Rats. Front Neurosci. 2019;13:1441 pubmed publisher
  • western blot; mouse; 1:3000; loading ...; fig 4g
Hua X, Sun D, Zhang W, Fu J, Tong J, Sun S, et al. P7C3-A20 alleviates fatty liver by shaping gut microbiota and inducing FGF21/FGF1, via the AMP-activated protein kinase/CREB regulated transcription coactivator 2 pathway. Br J Pharmacol. 2021;178:2111-2130 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 7e
Yang Y, Luo M, Zhang K, Zhang J, Gao T, Connell D, et al. Nedd4 ubiquitylates VDAC2/3 to suppress erastin-induced ferroptosis in melanoma. Nat Commun. 2020;11:433 pubmed publisher
  • western blot; mouse; loading ...; fig 3f
Oka S, Chin A, Park J, Ikeda S, Mizushima W, Ralda G, et al. Thioredoxin-1 maintains mitochondrial function via mTOR signaling in the heart. Cardiovasc Res. 2019;: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig s5a
  • western blot; mouse; 1:2000; loading ...; fig 5a
Zhu Y, Zhang Y, Huang X, Xie Y, Qu Y, Long H, et al. Z-Ligustilide protects vascular endothelial cells from oxidative stress and rescues high fat diet-induced atherosclerosis by activating multiple NRF2 downstream genes. Atherosclerosis. 2019;284:110-120 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 4a
Günther M, Al Nimer F, Piehl F, Risling M, Mathiesen T. Susceptibility to Oxidative Stress Is Determined by Genetic Background in Neuronal Cell Cultures. Eneuro. 2018;5: pubmed publisher
  • western blot; mouse; 1:1000; fig 6a
Pereira R, Tadinada S, Zasadny F, Oliveira K, Pires K, Olvera A, et al. OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance. EMBO J. 2017;36:2126-2145 pubmed publisher
  • immunohistochemistry; human; 1:1000; loading ...; fig 4a
Cabezas R, Vega Vela N, González Sanmiguel J, Gonzalez J, Esquinas P, Echeverria V, et al. PDGF-BB Preserves Mitochondrial Morphology, Attenuates ROS Production, and Upregulates Neuroglobin in an Astrocytic Model Under Rotenone Insult. Mol Neurobiol. 2018;55:3085-3095 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 5d
Loomis Z, Eigenberger P, Redinius K, Lisk C, Karoor V, Nozik Grayck E, et al. Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation. PLoS ONE. 2017;12:e0171219 pubmed publisher
  • western blot; human; loading ...; fig 4a
Ahn B, Coblentz P, Beharry A, Patel N, Judge A, Moylan J, et al. Diaphragm Abnormalities in Patients with End-Stage Heart Failure: NADPH Oxidase Upregulation and Protein Oxidation. Front Physiol. 2016;7:686 pubmed publisher
  • western blot; rat; 1:1000; fig 4b
Haffar T, Akoumi A, Bousette N. Lipotoxic Palmitate Impairs the Rate of β-Oxidation and Citric Acid Cycle Flux in Rat Neonatal Cardiomyocytes. Cell Physiol Biochem. 2016;40:969-981 pubmed
  • western blot; mouse; 1:1000; loading ...; fig 2d
Patche J, Girard D, Catan A, Boyer F, Dobi A, Planesse C, et al. Diabetes-induced hepatic oxidative stress: a new pathogenic role for glycated albumin. Free Radic Biol Med. 2017;102:133-148 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3b
Bettaieb A, Cremonini E, Kang H, Kang J, Haj F, Oteiza P. Anti-inflammatory actions of (-)-epicatechin in the adipose tissue of obese mice. Int J Biochem Cell Biol. 2016;81:383-392 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:200; loading ...; fig 1a
Suman S, Kumar S, N GOUEMO P, Datta K. Increased DNA double-strand break was associated with downregulation of repair and upregulation of apoptotic factors in rat hippocampus after alcohol exposure. Alcohol. 2016;54:45-50 pubmed publisher
  • western blot; mouse; fig 2
Mowry A, Kavazis A, Sirman A, Potts W, Hood W. Reproduction Does Not Adversely Affect Liver Mitochondrial Respiratory Function but Results in Lipid Peroxidation and Increased Antioxidants in House Mice. PLoS ONE. 2016;11:e0160883 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 5a
Griñan Ferré C, Sarroca S, Ivanova A, Puigoriol Illamola D, Aguado F, Camins A, et al. Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice. Aging (Albany NY). 2016;8:664-84 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 9a
  • western blot; rat; 1:1000; loading ...; fig 1a
Djamali A, Wilson N, Sadowski E, Zha W, Niles D, Hafez O, et al. Nox2 and Cyclosporine-Induced Renal Hypoxia. Transplantation. 2016;100:1198-210 pubmed publisher
  • western blot; mouse; 1:1000; fig 6
Barone R, Macaluso F, Sangiorgi C, Campanella C, Marino Gammazza A, Moresi V, et al. Skeletal muscle Heat shock protein 60 increases after endurance training and induces peroxisome proliferator-activated receptor gamma coactivator 1 α1 expression. Sci Rep. 2016;6:19781 pubmed publisher
Santin Y, Formoso K, Haidar F, Fuentes M, Bourgailh F, Hifdi N, et al. Inhalation of acidic nanoparticles prevents doxorubicin cardiotoxicity through improvement of lysosomal function. Theranostics. 2023;13:5435-5451 pubmed publisher
Sun G, Zheng Y, Fu X, Zhang W, Ren J, Ma S, et al. Single-cell transcriptomic atlas of mouse cochlear aging. Protein Cell. 2023;14:180-201 pubmed publisher
Liu X, Nie L, Zhang Y, Yan Y, Wang C, Colic M, et al. Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis. Nat Cell Biol. 2023;25:404-414 pubmed publisher
Valentijn F, Knoppert S, Pissas G, Rodrigues Díez R, Marquez Exposito L, Broekhuizen R, et al. CCN2 Aggravates the Immediate Oxidative Stress-DNA Damage Response following Renal Ischemia-Reperfusion Injury. Antioxidants (Basel). 2021;10: pubmed publisher
Yao F, Deng Y, Zhao Y, Mei Y, Zhang Y, Liu X, et al. A targetable LIFR-NF-κB-LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis. Nat Commun. 2021;12:7333 pubmed publisher
Batallé G, Bai X, Pouso Vázquez E, Roch G, Rodriguez L, Pol O. The Recovery of Cognitive and Affective Deficiencies Linked with Chronic Osteoarthritis Pain and Implicated Pathways by Slow-Releasing Hydrogen Sulfide Treatment. Antioxidants (Basel). 2021;10: pubmed publisher
Kovacevic S, Ivanov M, Zivotić M, Brkić P, Miloradovic Z, Jeremic R, et al. Immunohistochemical Analysis of 4-HNE, NGAL, and HO-1 Tissue Expression after Apocynin Treatment and HBO Preconditioning in Postischemic Acute Kidney Injury Induced in Spontaneously Hypertensive Rats. Antioxidants (Basel). 2021;10: pubmed publisher
Minati M, Libert M, Dahou H, Jacquemin P, Assi M. N-Acetylcysteine Reduces the Pro-Oxidant and Inflammatory Responses during Pancreatitis and Pancreas Tumorigenesis. Antioxidants (Basel). 2021;10: pubmed publisher
Fu X, An Y, Wang H, Li P, Lin J, Yuan J, et al. Deficiency of Klc2 Induces Low-Frequency Sensorineural Hearing Loss in C57BL/6 J Mice and Human. Mol Neurobiol. 2021;: pubmed publisher
Qu Y, Wang W, Chen T, Yang Y, Zhang Y, Wang D. The neuroprotection of deproteinized calf blood extractives injection against Alzheimer's disease via regulation of Nrf-2 signaling. Aging (Albany NY). 2021;13:11150-11169 pubmed publisher
Zhou Z, Liu X, Zhang S, Qi X, Zhang Q, Yard B, et al. Correlation between serum carnosinase concentration and renal damage in diabetic nephropathy patients. Amino Acids. 2021;53:687-700 pubmed publisher
Zhang Y, Swanda R, Nie L, Liu X, Wang C, Lee H, et al. mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation. Nat Commun. 2021;12:1589 pubmed publisher
Mesquita P, Lamb D, Godwin J, Osburn S, Ruple B, Moore J, et al. Effects of Resistance Training on the Redox Status of Skeletal Muscle in Older Adults. Antioxidants (Basel). 2021;10: pubmed publisher
Mu Y, Maharjan Y, Kumar Dutta R, Wei X, Kim J, Son J, et al. Pharmacological inhibition of catalase induces peroxisome leakage and suppression of LPS induced inflammatory response in Raw 264.7 cell. PLoS ONE. 2021;16:e0245799 pubmed publisher
Sun W, Tyurin V, Mikulska Ruminska K, Shrivastava I, Anthonymuthu T, Zhai Y, et al. Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal. Nat Chem Biol. 2021;: pubmed publisher
Gauba E, Sui S, Tian J, Driskill C, Jia K, Yu C, et al. Modulation of OSCP mitigates mitochondrial and synaptic deficits in a mouse model of Alzheimer's pathology. Neurobiol Aging. 2021;98:63-77 pubmed publisher
Sziva R, Fontányi Z, Pál É, Hadjadj L, Monori Kiss A, Horvath E, et al. Vitamin D Deficiency Induces Elevated Oxidative and Biomechanical Damage in Coronary Arterioles in Male Rats. Antioxidants (Basel). 2020;9: pubmed publisher
Kim J, Leem J, Hong H. Protective Effects of SPA0355, a Thiourea Analogue, Against Lipopolysaccharide-Induced Acute Kidney Injury in Mice. Antioxidants (Basel). 2020;9: pubmed publisher
Kim H, Kim D, Yoon H, Choi C, Oh Y, Jun H. Prevention of Oxidative Stress-Induced Pancreatic Beta Cell Damage by Broussonetia Kazinoki Siebold Fruit Extract Via the ERK-Nox4 Pathway. Antioxidants (Basel). 2020;9: pubmed publisher
Mayr L, Grabherr F, Schwärzler J, Reitmeier I, Sommer F, Gehmacher T, et al. Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease. Nat Commun. 2020;11:1775 pubmed publisher
Harandi V, Oliveira B, Allamand V, Friberg A, Fontes Oliveira C, Durbeej M. Antioxidants Reduce Muscular Dystrophy in the dy2J/dy2J Mouse Model of Laminin α2 Chain-Deficient Muscular Dystrophy. Antioxidants (Basel). 2020;9: pubmed publisher
Gai Z, Krajnc E, Samodelov S, Visentin M, Kullak Ublick G. Obeticholic Acid Ameliorates Valproic Acid-Induced Hepatic Steatosis and Oxidative Stress. Mol Pharmacol. 2020;97:314-323 pubmed publisher
Noblanc A, Klaassen A, Robaire B. The Exacerbation of Aging and Oxidative Stress in the Epididymis of Sod1 Null Mice. Antioxidants (Basel). 2020;9: pubmed publisher
Lee S, Han J, Lee S, Jung G, Min H, Song J, et al. Outcomes of Peptide Vaccine GV1001 Treatment in a Murine Model of Acute Noise-Induced Hearing Loss. Antioxidants (Basel). 2020;9: pubmed publisher
Estébanez B, Rodriguez A, Visavadiya N, Whitehurst M, Cuevas M, Gonzalez Gallego J, et al. Aerobic Training Down-Regulates Pentraxin 3 and Pentraxin 3/Toll-Like Receptor 4 Ratio, Irrespective of Oxidative Stress Response, in Elderly Subjects. Antioxidants (Basel). 2020;9: pubmed publisher
Lei G, Zhang Y, Koppula P, Liu X, Zhang J, Lin S, et al. The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression. Cell Res. 2020;30:146-162 pubmed publisher
Liao H, Zhang N, Meng Y, Feng H, Yang J, Li W, et al. Myricetin Alleviates Pathological Cardiac Hypertrophy via TRAF6/TAK1/MAPK and Nrf2 Signaling Pathway. Oxid Med Cell Longev. 2019;2019:6304058 pubmed publisher
Li J, Wang Q, Yang Y, Lei C, Yang F, Liang L, et al. GSTZ1 deficiency promotes hepatocellular carcinoma proliferation via activation of the KEAP1/NRF2 pathway. J Exp Clin Cancer Res. 2019;38:438 pubmed publisher
Rodriguez Garcia A, Morales M, Garrido García V, García Baquero I, Leivas A, Carreño Tarragona G, et al. Protein Carbonylation in Patients with Myelodysplastic Syndrome: An Opportunity for Deferasirox Therapy. Antioxidants (Basel). 2019;8: pubmed publisher
Srinivasan M, Bhopale K, Amer S, Wan J, Kaphalia L, Ansari G, et al. Linking Dysregulated AMPK Signaling and ER Stress in Ethanol-Induced Liver Injury in Hepatic Alcohol Dehydrogenase Deficient Deer Mice. Biomolecules. 2019;9: pubmed publisher
Lang X, Green M, Wang W, Yu J, Choi J, Jiang L, et al. Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11. Cancer Discov. 2019;9:1673-1685 pubmed publisher
Hsieh M, Choe J, Gadhvi J, Kim Y, Arguez M, Palmer M, et al. p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas. Cell Rep. 2019;28:1860-1878.e9 pubmed publisher
Ma L, Hua R, Tian Y, Cheng H, Fajardo R, Pearson J, et al. Connexin 43 hemichannels protect bone loss during estrogen deficiency. Bone Res. 2019;7:11 pubmed publisher
Uto K, Sakamoto S, Que W, Shimata K, Hashimoto S, Sakisaka M, et al. Hydrogen-rich solution attenuates cold ischemia-reperfusion injury in rat liver transplantation. BMC Gastroenterol. 2019;19:25 pubmed publisher
Kopp F, Elguindy M, Yalvac M, Zhang H, Chen B, Gillett F, et al. PUMILIO hyperactivity drives premature aging of Norad-deficient mice. elife. 2019;8: pubmed publisher
Ye B, Wang Q, Hu H, Shen Y, Fan C, Chen P, et al. Restoring autophagic flux attenuates cochlear spiral ganglion neuron degeneration by promoting TFEB nuclear translocation via inhibiting MTOR. Autophagy. 2019;15:998-1016 pubmed publisher
Hancock M, Hafstad A, Nabeebaccus A, Catibog N, Logan A, Smyrnias I, et al. Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise. elife. 2018;7: pubmed publisher
Tian X, Wang F, Luo Y, Ma S, Zhang N, Sun Y, et al. Protective Role of Nuclear Factor-Erythroid 2-Related Factor 2 Against Radiation-Induced Lung Injury and Inflammation. Front Oncol. 2018;8:542 pubmed publisher
Dhingra A, Bell B, Peachey N, Daniele L, Reyes Reveles J, Sharp R, et al. Microtubule-Associated Protein 1 Light Chain 3B, (LC3B) Is Necessary to Maintain Lipid-Mediated Homeostasis in the Retinal Pigment Epithelium. Front Cell Neurosci. 2018;12:351 pubmed publisher
Araya J, Tsubouchi K, Sato N, Ito S, Minagawa S, Hara H, et al. PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis. Autophagy. 2018;:1-17 pubmed publisher
Fang G, Hong L, Liu C, Yang Q, Zhang Q, Li Y, et al. Oxidative status of cardinal ligament in pelvic organ prolapse. Exp Ther Med. 2018;16:3293-3302 pubmed publisher
Pires P, Earley S. Neuroprotective effects of TRPA1 channels in the cerebral endothelium following ischemic stroke. elife. 2018;7: pubmed publisher
Yingchun H, Yahong M, Jiangping W, Xiaokui H, Xiaohong Z. Increased inflammation, endoplasmic reticulum stress and oxidative stress in endothelial and macrophage cells exacerbate atherosclerosis in ApoCIII transgenic mice. Lipids Health Dis. 2018;17:220 pubmed publisher
Zhang Y, Shi J, Liu X, Feng L, Gong Z, Koppula P, et al. BAP1 links metabolic regulation of ferroptosis to tumour suppression. Nat Cell Biol. 2018;20:1181-1192 pubmed publisher
Hua Y, Chen H, Zhao X, Liu M, Jin W, Yan W, et al. Alda‑1, an aldehyde dehydrogenase‑2 agonist, improves long‑term survival in rats with chronic heart failure following myocardial infarction. Mol Med Rep. 2018;18:3159-3166 pubmed publisher
Wen J, Garg N. Manganese superoxide dismutase deficiency exacerbates the mitochondrial ROS production and oxidative damage in Chagas disease. PLoS Negl Trop Dis. 2018;12:e0006687 pubmed publisher
Giacci M, Bartlett C, Smith N, Iyer K, Toomey L, Jiang H, et al. Oligodendroglia Are Particularly Vulnerable to Oxidative Damage after Neurotrauma In Vivo. J Neurosci. 2018;38:6491-6504 pubmed publisher
Stacchiotti A, Favero G, Lavazza A, Monsalve M, Rodella L, Rezzani R. Taurine Supplementation Alleviates Puromycin Aminonucleoside Damage by Modulating Endoplasmic Reticulum Stress and Mitochondrial-Related Apoptosis in Rat Kidney. Nutrients. 2018;10: pubmed publisher
Zhang J, Lai Z, Shi L, Tian Y, Luo A, Xu Z, et al. Repeated superovulation increases the risk of osteoporosis and cardiovascular diseases by accelerating ovarian aging in mice. Aging (Albany NY). 2018;10:1089-1102 pubmed publisher
Ziros P, Habeos I, Chartoumpekis D, Ntalampyra E, Somm E, Renaud C, et al. NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland. Thyroid. 2018;28:780-798 pubmed publisher
Roy A, Ahmed A, DiStefano P, Chi L, Khyzha N, Galjart N, et al. The transcriptional regulator CCCTC-binding factor limits oxidative stress in endothelial cells. J Biol Chem. 2018;293:8449-8461 pubmed publisher
Lee H, Lim S, Lee H, Yoo H, Kim H. Yuk-Mi-Jihwang-Tang, a Traditional Korean Multiple Herbal Formulae, Improves Hippocampal Memory on Scopolamine Injection-Induced Amnesia Model of C57BL/6 Mice. Evid Based Complement Alternat Med. 2018;2018:2821040 pubmed publisher
Sonowal H, Pal P, Shukla K, Saxena A, Srivastava S, Ramana K. Aldose reductase inhibitor, fidarestat prevents doxorubicin-induced endothelial cell death and dysfunction. Biochem Pharmacol. 2018;150:181-190 pubmed publisher
Wu Q, Xiao Y, Duan M, Yuan Y, Jiang X, Yang Z, et al. Aucubin protects against pressure overload-induced cardiac remodelling via the β3 -adrenoceptor-neuronal NOS cascades. Br J Pharmacol. 2018;175:1548-1566 pubmed publisher
Jadhav K, Xu Y, Xu Y, Li Y, Xu J, Zhu Y, et al. Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR. Mol Metab. 2018;9:131-140 pubmed publisher
Gifford J, Trinity J, Kwon O, Layec G, Garten R, Park S, et al. Altered skeletal muscle mitochondrial phenotype in COPD: disease vs. disuse. J Appl Physiol (1985). 2018;124:1045-1053 pubmed publisher
Hyatt H, Zhang Y, Hood W, Kavazis A. Physiological, mitochondrial, and oxidative stress differences in the presence or absence of lactation in rats. Reprod Biol Endocrinol. 2018;16:2 pubmed publisher
Abebe T, Mahadevan J, Bogachus L, Hahn S, Black M, Oseid E, et al. Nrf2/antioxidant pathway mediates β cell self-repair after damage by high-fat diet-induced oxidative stress. JCI Insight. 2017;2: pubmed publisher
Anantharam P, Whitley E, Mahama B, Kim D, Sarkar S, Santana C, et al. Cobinamide is effective for treatment of hydrogen sulfide-induced neurological sequelae in a mouse model. Ann N Y Acad Sci. 2017;1408:61-78 pubmed publisher
Khan M, Xiao J, Patel D, Ledoux M. DNA damage and neurodegenerative phenotypes in aged Ciz1 null mice. Neurobiol Aging. 2018;62:180-190 pubmed publisher
Stokman G, Kors L, Bakker P, Rampanelli E, Claessen N, Teske G, et al. NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity. J Exp Med. 2017;214:2405-2420 pubmed publisher
Chen H, Tsai T, Tsai Y, Liao J, Yen C, Chen C. Kefir peptides prevent high-fructose corn syrup-induced non-alcoholic fatty liver disease in a murine model by modulation of inflammation and the JAK2 signaling pathway. Nutr Diabetes. 2016;6:e237 pubmed publisher
Martin J, Kephart W, Haun C, McCloskey A, Shake J, Mobley C, et al. Impact of external pneumatic compression target inflation pressure on transcriptome-wide RNA expression in skeletal muscle. Physiol Rep. 2016;4: pubmed
Wawrzyniak N, Joseph A, Levin D, Gundermann D, Leeuwenburgh C, Sandesara B, et al. Idiopathic chronic fatigue in older adults is linked to impaired mitochondrial content and biogenesis signaling in skeletal muscle. Oncotarget. 2016;7:52695-52709 pubmed publisher
Zhao Q, Peng Y, Huang K, Lei Y, Liu H, Tao Y, et al. Salvianolate Protects Hepatocytes from Oxidative Stress by Attenuating Mitochondrial Injury. Evid Based Complement Alternat Med. 2016;2016:5408705 pubmed publisher
Liu M, Verma N, Peng X, Srodulski S, Morris A, Chow M, et al. Hyperamylinemia Increases IL-1β Synthesis in the Heart via Peroxidative Sarcolemmal Injury. Diabetes. 2016;65:2772-83 pubmed publisher
Softic S, Boucher J, Solheim M, Fujisaka S, Haering M, Homan E, et al. Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD. Diabetes. 2016;65:2187-200 pubmed publisher
Rubio Navarro A, Carril M, Padro D, Guerrero Hue M, Tarin C, Samaniego R, et al. CD163-Macrophages Are Involved in Rhabdomyolysis-Induced Kidney Injury and May Be Detected by MRI with Targeted Gold-Coated Iron Oxide Nanoparticles. Theranostics. 2016;6:896-914 pubmed publisher
Liu C, Yang Q, Fang G, Li B, Wu D, Guo W, et al. Collagen metabolic disorder induced by oxidative stress in human uterosacral ligament‑derived fibroblasts: A possible pathophysiological mechanism in pelvic organ prolapse. Mol Med Rep. 2016;13:2999-3008 pubmed publisher
product information
CatalogNumber :
ab46545
ItemName :
Anti-4 Hydroxynonenal antibody
Category :
Antibody
Host :
Rabbit
Clonality :
Polyclonal
Conjugate :
Unconjugated
Size :
100 µg
SpeciesSummary :
Dog, Hu, Many, Ms, Rat
Application Summary :
ELISA, IHC-Fr, IHC-P, WB
company information
Abcam
Discovery Drive
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