This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-Interferon alpha/beta receptor 1 antibody [EP899Y]
catalog :
ab45172
quantity :
10 µl, 100 µl
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
EP899Y
reactivity :
human
application :
western blot, immunoprecipitation, flow cytometry, blocking or activating experiments
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 3f
Xu W, Ma C, Zhang Q, Zhao R, Hu D, Zhang X, et al. PJA1 Coordinates with the SMC5/6 Complex To Restrict DNA Viruses and Episomal Genes in an Interferon-Independent Manner. J Virol. 2018;92: pubmed publisher
  • blocking or activating experiments; human; loading ...; fig 7c
Tian J, Zhang X, Wu H, Liu C, Li Z, Hu X, et al. Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes. Front Microbiol. 2015;6:886 pubmed publisher
  • western blot; human; 1:20000
Nokes B, Cunliffe H, Lafleur B, Mount D, Livingston R, Futscher B, et al. In Vitro Assessment of the Inflammatory Breast Cancer Cell Line SUM 149: Discovery of 2 Single Nucleotide Polymorphisms in the RNase L Gene. J Cancer. 2013;4:104-16 pubmed publisher
Cheng M, Niu Y, Fan J, Chi X, Liu X, Yang W. Interferon down-regulation of miR-1225-3p as an antiviral mechanism through modulating Grb2-associated binding protein 3 expression. J Biol Chem. 2018;293:5975-5986 pubmed publisher
Wang C, Sun M, Yuan X, Ji L, Jin Y, Cardona C, et al. Enterovirus 71 suppresses interferon responses by blocking Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling through inducing karyopherin-?1 degradation. J Biol Chem. 2017;292:10262-10274 pubmed publisher
Duncan C, Mohamad S, Young D, Skelton A, Leahy T, Munday D, et al. Human IFNAR2 deficiency: Lessons for antiviral immunity. Sci Transl Med. 2015;7:307ra154 pubmed publisher
Wan S, Pestka S, Jubin R, Lyu Y, Tsai Y, Liu L. Chemotherapeutics and radiation stimulate MHC class I expression through elevated interferon-beta signaling in breast cancer cells. PLoS ONE. 2012;7:e32542 pubmed publisher
Negrotto S, J De Giusti C, Lapponi M, Etulain J, Rivadeneyra L, Pozner R, et al. Expression and functionality of type I interferon receptor in the megakaryocytic lineage. J Thromb Haemost. 2011;9:2477-85 pubmed publisher
Leang R, Wu T, Hwang S, Liang L, Tong L, Truong J, et al. The anti-interferon activity of conserved viral dUTPase ORF54 is essential for an effective MHV-68 infection. PLoS Pathog. 2011;7:e1002292 pubmed publisher
Tsai Y, Pestka S, Wang L, Runnels L, Wan S, Lyu Y, et al. Interferon-? signaling contributes to Ras transformation. PLoS ONE. 2011;6:e24291 pubmed publisher
Piganis R, de Weerd N, Gould J, Schindler C, Mansell A, Nicholson S, et al. Suppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon alpha receptor (IFNAR1)-associated tyrosine kinase Tyk2. J Biol Chem. 2011;286:33811-8 pubmed publisher
Mutocheluh M, Hindle L, Aresté C, Chanas S, Butler L, Lowry K, et al. Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor-2 inhibits type 1 interferon signalling by targeting interferon-stimulated gene factor-3. J Gen Virol. 2011;92:2394-8 pubmed publisher
Saloura V, Wang L, Fridlender Z, Sun J, Cheng G, Kapoor V, et al. Evaluation of an attenuated vesicular stomatitis virus vector expressing interferon-beta for use in malignant pleural mesothelioma: heterogeneity in interferon responsiveness defines potential efficacy. Hum Gene Ther. 2010;21:51-64 pubmed publisher
Opitz C, Litzenburger U, Lutz C, Lanz T, Tritschler I, Köppel A, et al. Toll-like receptor engagement enhances the immunosuppressive properties of human bone marrow-derived mesenchymal stem cells by inducing indoleamine-2,3-dioxygenase-1 via interferon-beta and protein kinase R. Stem Cells. 2009;27:909-19 pubmed publisher
product information
CatalogNumber :
ab45172
ItemName :
Anti-Interferon alpha/beta receptor 1 antibody [EP899Y]
Category :
Antibody
Host :
Rabbit
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
EP899Y
Size :
10 µl, 100 µl
SpeciesSummary :
Hu
Application Summary :
Flow Cyt, IP, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK