This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Notch1 antibody [A6]
catalog :
ab44986
quantity :
500 ul
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
A6
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, proximity ligation assay
citations: 10
Published Application/Species/Sample/DilutionReference
  • proximity ligation assay; human; 1:50; fig 5
  • immunohistochemistry; mouse; 1:25; fig s11
Wu X, Fleming A, Ricketts T, Pavel M, Virgin H, Menzies F, et al. Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis. Nat Commun. 2016;7:10533 pubmed publisher
  • immunocytochemistry; human; 1:30
Singla R, Wang J, Singla D. Regulation of Notch 1 signaling in THP-1 cells enhances M2 macrophage differentiation. Am J Physiol Heart Circ Physiol. 2014;307:H1634-42 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200
Wang H, Huang X, Zhang J, Shao N, Chen L, Ma D, et al. The expression of VEGF and Dll4/Notch pathway molecules in ovarian cancer. Clin Chim Acta. 2014;436:243-8 pubmed publisher
Xiong Z, Ding J, Zhou J, Yao S, Zheng J, Guo X. Correlation between the HIF-1α/Notch signaling pathway and Modic changes in nucleus pulposus cells isolated from patients with low back pain. BMC Musculoskelet Disord. 2020;21:500 pubmed publisher
Srinivasan T, Walters J, Bu P, Than E, Tung K, Chen K, et al. NOTCH Signaling Regulates Asymmetric Cell Fate of Fast- and Slow-Cycling Colon Cancer-Initiating Cells. Cancer Res. 2016;76:3411-21 pubmed publisher
Beschorner R, Waidelich J, Trautmann K, Psaras T, Schittenhelm J. Notch receptors in human choroid plexus tumors. Histol Histopathol. 2013;28:1055-63 pubmed publisher
Campos B, Wan F, Farhadi M, Ernst A, Zeppernick F, Tagscherer K, et al. Differentiation therapy exerts antitumor effects on stem-like glioma cells. Clin Cancer Res. 2010;16:2715-28 pubmed publisher
Grogan S, Miyaki S, Asahara H, D Lima D, Lotz M. Mesenchymal progenitor cell markers in human articular cartilage: normal distribution and changes in osteoarthritis. Arthritis Res Ther. 2009;11:R85 pubmed publisher
Kutlesa S, Zayas J, Valle A, Levy R, Jurecic R. T-cell differentiation of multipotent hematopoietic cell line EML in the OP9-DL1 coculture system. Exp Hematol. 2009;37:909-23 pubmed publisher
Matesic L, Haines D, Copeland N, Jenkins N. Itch genetically interacts with Notch1 in a mouse autoimmune disease model. Hum Mol Genet. 2006;15:3485-97 pubmed
product information
Catalog Number :
ab44986
Product Name :
Notch1 antibody [A6]
Host Species :
Mouse
Clonality :
monoclonal
Product Type :
Primary antibodies
Size :
500 ul
SwissProtID :
P46531
Isotype :
IgG2b
CrossReactivity :
Reacts with: Human, Mouse.
Application Summary :
Flow Cyt, ICC/IF, IHC-P
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
Stefan.Pritchard@abcam.com, eCommerce@abcam.com, Vicky.Yang@abcam.com
https://www.abcam.com
888-7722226
headquarters: UK