This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-mono and dimethyl Arginine antibody [7E6]
catalog :
ab412
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7E6
reactivity :
human, rat
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, chromatin immunoprecipitation
citations: 31
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; loading ...; fig 1g
Liu Y, Li L, Liu X, Wang Y, Liu L, Peng L, et al. Arginine methylation of SHANK2 by PRMT7 promotes human breast cancer metastasis through activating endosomal FAK signalling. elife. 2020;9: pubmed publisher
  • western blot; rat; loading ...; fig 5g
Hou W, Nemitz S, Schopper S, Nielsen M, Kessels M, Qualmann B. Arginine Methylation by PRMT2 Controls the Functions of the Actin Nucleator Cobl. Dev Cell. 2018;45:262-275.e8 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 3e
  • immunohistochemistry; human; 1:200; loading ...; fig 2c
Wu T, Yao Y, Lai I, Lai C, Lin P, Yang W. Loading of PAX3 to Mitotic Chromosomes Is Mediated by Arginine Methylation and Associated with Waardenburg Syndrome. J Biol Chem. 2015;290:20556-64 pubmed publisher
Kang H, Eom H, Kim H, Myung K, Kwon H, Choi J. Thrap3 promotes R-loop resolution via interaction with methylated DDX5. Exp Mol Med. 2021;53:1602-1611 pubmed publisher
Yoneda R, Ueda N, Uranishi K, Hirasaki M, Kurokawa R. Long noncoding RNA pncRNA-D reduces cyclin D1 gene expression and arrests cell cycle through RNA m6A modification. J Biol Chem. 2020;295:5626-5639 pubmed publisher
Woodsmith J, Casado Medrano V, Benlasfer N, Eccles R, Hutten S, Heine C, et al. Interaction modulation through arrays of clustered methyl-arginine protein modifications. Life Sci Alliance. 2018;1:e201800178 pubmed publisher
Gasperini L, Rossi A, Cornella N, Peroni D, Zuccotti P, Potrich V, et al. The hnRNP raly regulates PRMT1 expression and interacts with the ALS-linked protein FUS: implication for reciprocal cellular localization. Mol Biol Cell. 2018;:mbcE18020108 pubmed publisher
Cui W, Yoneda R, Ueda N, Kurokawa R. Arginine methylation of translocated in liposarcoma (TLS) inhibits its binding to long noncoding RNA, abrogating TLS-mediated repression of CBP/p300 activity. J Biol Chem. 2018;293:10937-10948 pubmed publisher
Ganesan M, Tikhanovich I, Vangimalla S, Dagur R, Wang W, Poluektova L, et al. Demethylase JMJD6 as a New Regulator of Interferon Signaling: Effects of HCV and Ethanol Metabolism. Cell Mol Gastroenterol Hepatol. 2018;5:101-112 pubmed publisher
Ariyachet C, Beisel C, Li X, Lorrey S, Mackenzie O, Martin P, et al. Post-translational modification directs nuclear and hyphal tip localization of Candida albicans mRNA-binding protein Slr1. Mol Microbiol. 2017;104:499-519 pubmed publisher
Yang J, Chiou Y, Fu S, Shih I, Weng T, Lin W, et al. Arginine methylation of hnRNPK negatively modulates apoptosis upon DNA damage through local regulation of phosphorylation. Nucleic Acids Res. 2014;42:9908-24 pubmed publisher
Casadio F, Lu X, Pollock S, LeRoy G, Garcia B, Muir T, et al. H3R42me2a is a histone modification with positive transcriptional effects. Proc Natl Acad Sci U S A. 2013;110:14894-9 pubmed publisher
Slade D, Subramanian V, Fuhrmann J, Thompson P. Chemical and biological methods to detect post-translational modifications of arginine. Biopolymers. 2014;101:133-43 pubmed publisher
Uhlmann T, Geoghegan V, Thomas B, Ridlova G, Trudgian D, Acuto O. A method for large-scale identification of protein arginine methylation. Mol Cell Proteomics. 2012;11:1489-99 pubmed publisher
Beltran Alvarez P, Pagans S, Brugada R. The cardiac sodium channel is post-translationally modified by arginine methylation. J Proteome Res. 2011;10:3712-9 pubmed publisher
Bikkavilli R, Malbon C. Arginine methylation of G3BP1 in response to Wnt3a regulates ?-catenin mRNA. J Cell Sci. 2011;124:2310-20 pubmed publisher
He W, Ma X, Yang X, Zhao Y, Qiu J, Hang H. A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage. Nucleic Acids Res. 2011;39:4719-27 pubmed publisher
Cha B, Kim W, Kim Y, Hwang B, Park S, Yoon J, et al. Methylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signaling. Oncogene. 2011;30:2379-89 pubmed publisher
Blifernez O, Wobbe L, Niehaus K, Kruse O. Protein arginine methylation modulates light-harvesting antenna translation in Chlamydomonas reinhardtii. Plant J. 2011;65:119-130 pubmed publisher
Kowenz Leutz E, Pless O, Dittmar G, Knoblich M, Leutz A. Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code. EMBO J. 2010;29:1105-15 pubmed publisher
McBride A, Conboy A, Brown S, Ariyachet C, Rutledge K. Specific sequences within arginine-glycine-rich domains affect mRNA-binding protein function. Nucleic Acids Res. 2009;37:4322-30 pubmed publisher
Koyuncu O, Dobner T. Arginine methylation of human adenovirus type 5 L4 100-kilodalton protein is required for efficient virus production. J Virol. 2009;83:4778-90 pubmed publisher
Jobert L, Argentini M, Tora L. PRMT1 mediated methylation of TAF15 is required for its positive gene regulatory function. Exp Cell Res. 2009;315:1273-86 pubmed publisher
Gomes A, Young G, Wang Y, Zong C, Eghbali M, Drews O, et al. Contrasting proteome biology and functional heterogeneity of the 20 S proteasome complexes in mammalian tissues. Mol Cell Proteomics. 2009;8:302-15 pubmed publisher
Gupta P, Ho P, Huq M, Khan A, Tsai N, Wei L. PKCepsilon stimulated arginine methylation of RIP140 for its nuclear-cytoplasmic export in adipocyte differentiation. PLoS ONE. 2008;3:e2658 pubmed publisher
Choi S, Jung C, Kim J, Im D. PRMT3 inhibits ubiquitination of ribosomal protein S2 and together forms an active enzyme complex. Biochim Biophys Acta. 2008;1780:1062-9 pubmed publisher
Mastronardi F, Tsui H, Winer S, Wood D, Selvanantham T, Galligan C, et al. Synergy between paclitaxel plus an exogenous methyl donor in the suppression of murine demyelinating diseases. Mult Scler. 2007;13:596-609 pubmed
Lawson B, Manenkova Y, Ahamed J, Chen X, Zou J, Baccala R, et al. Inhibition of transmethylation down-regulates CD4 T cell activation and curtails development of autoimmunity in a model system. J Immunol. 2007;178:5366-74 pubmed
Nien W, Dauphinee S, Moffat L, Too C. Overexpression of the mTOR alpha4 phosphoprotein activates protein phosphatase 2A and increases Stat1alpha binding to PIAS1. Mol Cell Endocrinol. 2007;263:10-7 pubmed
Wagner S, Weber S, Kleinschmidt M, Nagata K, Bauer U. SET-mediated promoter hypoacetylation is a prerequisite for coactivation of the estrogen-responsive pS2 gene by PRMT1. J Biol Chem. 2006;281:27242-50 pubmed
Komyod W, Bauer U, Heinrich P, Haan S, Behrmann I. Are STATS arginine-methylated?. J Biol Chem. 2005;280:21700-5 pubmed
product information
CatalogNumber :
ab412
ItemName :
Anti-mono and dimethyl Arginine antibody [7E6]
Category :
Antibody
Host :
Mouse
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
7E6
Size :
100 µg
Application Summary :
ChIP, ELISA, IP
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
Stefan.Pritchard@abcam.com, eCommerce@abcam.com, Vicky.Yang@abcam.com
https://www.abcam.com
888-7722226
headquarters: UK