This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Lamin A + C antibody [JOL2]
catalog :
ab40567
quantity :
2 ml
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
JOL2
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section, other
citations: 20
Published Application/Species/Sample/DilutionReference
  • other; human; 1:100; loading ...
James C, Müller M, Goldberg M, Lenz C, Urlaub H, Kehlenbach R. Proteomic mapping by rapamycin-dependent targeting of APEX2 identifies binding partners of VAPB at the inner nuclear membrane. J Biol Chem. 2019;294:16241-16254 pubmed publisher
  • western blot; human; 1:250; loading ...; fig 2a
Musante L, Püttmann L, Kahrizi K, Garshasbi M, Hu H, Stehr H, et al. Mutations of the aminoacyl-tRNA-synthetases SARS and WARS2 are implicated in the etiology of autosomal recessive intellectual disability. Hum Mutat. 2017;38:621-636 pubmed publisher
  • western blot; human; loading ...; fig 4a
Duclos C, Champagne A, Carrier J, Saucier C, Lavoie C, Denault J. Caspase-mediated proteolysis of the sorting nexin 2 disrupts retromer assembly and potentiates Met/hepatocyte growth factor receptor signaling. Cell Death Discov. 2017;3:16100 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 7a
Sierra Potchanant E, Cerabona D, Sater Z, He Y, Sun Z, Gehlhausen J, et al. INPP5E Preserves Genomic Stability through Regulation of Mitosis. Mol Cell Biol. 2017;37: pubmed publisher
  • immunohistochemistry - frozen section; human; loading ...; fig 3b
Chen J, King O, Zhang Y, Clayton N, Spencer C, Wentworth B, et al. Morpholino-mediated Knockdown of DUX4 Toward Facioscapulohumeral Muscular Dystrophy Therapeutics. Mol Ther. 2016;24:1405-11 pubmed publisher
  • immunocytochemistry; human; 1:30; fig 3a
Fahrenkrog B, Martinelli V, Nilles N, Fruhmann G, Chatel G, Juge S, et al. Expression of Leukemia-Associated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype. PLoS ONE. 2016;11:e0152321 pubmed publisher
  • western blot; human; 1:200
Jafferali M, Vijayaraghavan B, Figueroa R, Crafoord E, Gudise S, Larsson V, et al. MCLIP, an effective method to detect interactions of transmembrane proteins of the nuclear envelope in live cells. Biochim Biophys Acta. 2014;1838:2399-403 pubmed publisher
  • western blot; human; 1:2000; fig 2
Sánchez Osuna M, García Belinchón M, Iglesias Guimarais V, Gil Guiñón E, Casanelles E, Yuste V. Caspase-activated DNase is necessary and sufficient for oligonucleosomal DNA breakdown, but not for chromatin disassembly during caspase-dependent apoptosis of LN-18 glioblastoma cells. J Biol Chem. 2014;289:18752-69 pubmed publisher
Novak J, Mázala D, Nearing M, Hindupur R, Uapinyoying P, Habib N, et al. Human muscle stem cells are refractory to aging. Aging Cell. 2021;20:e13411 pubmed publisher
Jühlen R, Martinelli V, Vinci C, Breckpot J, Fahrenkrog B. Centrosome and ciliary abnormalities in fetal akinesia deformation sequence human fibroblasts. Sci Rep. 2020;10:19301 pubmed publisher
Borroni A, Emanuelli A, Shah P, Ilic N, Apel Sarid L, Paolini B, et al. Smurf2 regulates stability and the autophagic-lysosomal turnover of lamin A and its disease-associated form progerin. Aging Cell. 2018;17: pubmed publisher
Qi L, Song Y, Chan T, Yang H, Lin C, Tay D, et al. An RNA editing/dsRNA binding-independent gene regulatory mechanism of ADARs and its clinical implication in cancer. Nucleic Acids Res. 2017;45:10436-10451 pubmed publisher
Zhang Y, King O, Rahimov F, Jones T, Ward C, Kerr J, et al. Human skeletal muscle xenograft as a new preclinical model for muscle disorders. Hum Mol Genet. 2014;23:3180-8 pubmed publisher
Iglesias Guimarais V, Gil Guiñón E, Gabernet G, García Belinchón M, Sánchez Osuna M, Casanelles E, et al. Apoptotic DNA degradation into oligonucleosomal fragments, but not apoptotic nuclear morphology, relies on a cytosolic pool of DFF40/CAD endonuclease. J Biol Chem. 2012;287:7766-79 pubmed publisher
Mamchaoui K, Trollet C, Bigot A, Negroni E, Chaouch S, Wolff A, et al. Immortalized pathological human myoblasts: towards a universal tool for the study of neuromuscular disorders. Skelet Muscle. 2011;1:34 pubmed publisher
Harten I, Zahr R, Lemire J, Machan J, Moses M, Doiron R, et al. Age-dependent loss of MMP-3 in Hutchinson-Gilford progeria syndrome. J Gerontol A Biol Sci Med Sci. 2011;66:1201-7 pubmed publisher
Gudise S, Figueroa R, Lindberg R, Larsson V, Hallberg E. Samp1 is functionally associated with the LINC complex and A-type lamina networks. J Cell Sci. 2011;124:2077-85 pubmed publisher
Harrigan J, Belotserkovskaya R, Coates J, Dimitrova D, Polo S, Bradshaw C, et al. Replication stress induces 53BP1-containing OPT domains in G1 cells. J Cell Biol. 2011;193:97-108 pubmed publisher
Toulany M, Schickfluss T, Eicheler W, Kehlbach R, Schittek B, Rodemann H. Impact of oncogenic K-RAS on YB-1 phosphorylation induced by ionizing radiation. Breast Cancer Res. 2011;13:R28 pubmed publisher
Negroni E, Riederer I, Chaouch S, Belicchi M, Razini P, Di Santo J, et al. In vivo myogenic potential of human CD133+ muscle-derived stem cells: a quantitative study. Mol Ther. 2009;17:1771-8 pubmed publisher
product information
Catalog Number :
ab40567
Product Name :
Lamin A + C antibody [JOL2]
Host Species :
Mouse
Clonality :
monoclonal
Product Type :
Primary antibodies
Size :
2 ml
SwissProtID :
P02545
Isotype :
IgG1
CrossReactivity :
Reacts with: Human, African Green Monkey.
Application Summary :
Flow Cyt, ICC/IF, IHC-Fr, IHC-P, IP, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
Stefan.Pritchard@abcam.com, eCommerce@abcam.com, Vicky.Yang@abcam.com
https://www.abcam.com
888-7722226
headquarters: UK