This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Glucose Transporter GLUT1 antibody [SPM498]
catalog :
ab40084
quantity :
500 ul
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SPM498
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 52
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:500; loading ...; fig 5b
  • western blot; mouse; 1:5000; loading ...; fig 5d
Lee J, Hong J, Yoon B, Son K, Lee K, Im D, et al. Expression of Cellular Receptors in the Ischemic Hemisphere of Mice with Increased Glucose Uptake. Exp Neurobiol. 2020;29:70-79 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s2a
Trevisan A, Bauer M, Brindley R, Currie K, Carter B. Jedi-1 deficiency increases sensory neuron excitability through a non-cell autonomous mechanism. Sci Rep. 2020;10:1300 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 5c
Gorth D, Shapiro I, Risbud M. Transgenic mice overexpressing human TNF-α experience early onset spontaneous intervertebral disc herniation in the absence of overt degeneration. Cell Death Dis. 2018;10:7 pubmed publisher
  • western blot; human; loading ...; fig 1b
Zeng C, Wu Q, Wang J, Yao B, Ma L, Yang Z, et al. NOX4 supports glycolysis and promotes glutamine metabolism in non-small cell lung cancer cells. Free Radic Biol Med. 2016;101:236-248 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6b
Prieto P, Fernandez Velasco M, Fernández Santos M, Sanchez P, Terrón V, Martín Sanz P, et al. Cell Expansion-Dependent Inflammatory and Metabolic Profile of Human Bone Marrow Mesenchymal Stem Cells. Front Physiol. 2016;7:548 pubmed
  • immunohistochemistry - frozen section; rat; 1:1000; loading ...; fig 9a
Kalyan Masih P, Vega Torres J, Miles C, Haddad E, Rainsbury S, Baghchechi M, et al. Western High-Fat Diet Consumption during Adolescence Increases Susceptibility to Traumatic Stress while Selectively Disrupting Hippocampal and Ventricular Volumes. Eneuro. 2016;3: pubmed
  • western blot; mouse; loading ...; fig 7b
Zhang L, Justus S, Xu Y, Pluchenik T, Hsu C, Yang J, et al. Reprogramming towards anabolism impedes degeneration in a preclinical model of retinitis pigmentosa. Hum Mol Genet. 2016;25:4244-4255 pubmed publisher
  • immunocytochemistry; rat; 1:10; fig 1d
Tome M, Herndon J, Schaefer C, Jacobs L, Zhang Y, Jarvis C, et al. P-glycoprotein traffics from the nucleus to the plasma membrane in rat brain endothelium during inflammatory pain. J Cereb Blood Flow Metab. 2016;36:1913-1928 pubmed
  • western blot; human; loading ...; fig 3b
Barquissau V, Beuzelin D, Pisani D, Beranger G, Mairal A, Montagner A, et al. White-to-brite conversion in human adipocytes promotes metabolic reprogramming towards fatty acid anabolic and catabolic pathways. Mol Metab. 2016;5:352-365 pubmed publisher
  • immunohistochemistry; human; 1:100; loading ...; fig 3c
Bourseau Guilmain E, Menard J, Lindqvist E, Indira Chandran V, Christianson H, Cerezo Magaña M, et al. Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells. Nat Commun. 2016;7:11371 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 5d
Albert V, Svensson K, Shimobayashi M, Colombi M, Munoz S, Jimenez V, et al. mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue. EMBO Mol Med. 2016;8:232-46 pubmed publisher
  • immunocytochemistry; human; 1:300; fig 3
Miura S, Sato K, Kato Negishi M, Teshima T, Takeuchi S. Fluid shear triggers microvilli formation via mechanosensitive activation of TRPV6. Nat Commun. 2015;6:8871 pubmed publisher
  • immunocytochemistry; mouse; 1:200; fig 3
Tsuneki M, Hardee S, Michaud M, Morotti R, Lavik E, Madri J. A hydrogel-endothelial cell implant mimics infantile hemangioma: modulation by survivin and the Hippo pathway. Lab Invest. 2015;95:765-80 pubmed publisher
  • western blot; mouse; loading ...; fig 3,7,8
Schisler J, Grevengoed T, Pascual F, Cooper D, Ellis J, Paul D, et al. Cardiac energy dependence on glucose increases metabolites related to glutathione and activates metabolic genes controlled by mechanistic target of rapamycin. J Am Heart Assoc. 2015;4: pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Nogueira A, Sogayar M, Colquhoun A, Siqueira S, Nogueira A, Marchiori P, et al. Existence of a potential neurogenic system in the adult human brain. J Transl Med. 2014;12:75 pubmed publisher
  • western blot; rat; 1:1000
Morato P, Lollo P, Moura C, Batista T, Camargo R, Carneiro E, et al. Whey protein hydrolysate increases translocation of GLUT-4 to the plasma membrane independent of insulin in wistar rats. PLoS ONE. 2013;8:e71134 pubmed publisher
  • immunocytochemistry; human; 1:100
  • western blot; human; 1:500
Pyla R, Poulose N, Jun J, Segar L. Expression of conventional and novel glucose transporters, GLUT1, -9, -10, and -12, in vascular smooth muscle cells. Am J Physiol Cell Physiol. 2013;304:C574-89 pubmed publisher
  • western blot; rat
Kim J, Hwang I, Choi S, Lee H, Lee Y, Goo J, et al. Aqueous extract of Liriope platyphylla, a traditional Chinese medicine, significantly inhibits abdominal fat accumulation and improves glucose regulation in OLETF type II diabetes model rats. Lab Anim Res. 2012;28:181-91 pubmed publisher
Feliciano D, Ott C, Espinosa Medina I, Weigel A, Benedetti L, Milano K, et al. YAP1 nuclear efflux and transcriptional reprograming follow membrane diminution upon VSV-G-induced cell fusion. Nat Commun. 2021;12:4502 pubmed publisher
He J, Li C, Lee H, Shin D, Chern Y, Pereira De Carvalho B, et al. MIG-6 is essential for promoting glucose metabolic reprogramming and tumor growth in triple-negative breast cancer. EMBO Rep. 2021;22:e50781 pubmed publisher
Novais E, Tran V, Miao J, Slaver K, Sinensky A, Dyment N, et al. Comparison of inbred mouse strains shows diverse phenotypic outcomes of intervertebral disc aging. Aging Cell. 2020;19:e13148 pubmed publisher
Sun Y, Oravecz Wilson K, Bridges S, McEachin R, Wu J, Kim S, et al. miR-142 controls metabolic reprogramming that regulates dendritic cell activation. J Clin Invest. 2019;130:2029-2042 pubmed publisher
Freemerman A, Zhao L, Pingili A, Teng B, Cozzo A, Fuller A, et al. Myeloid Slc2a1-Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1. J Immunol. 2019;202:1265-1286 pubmed publisher
Sifat A, Vaidya B, Kaisar M, Cucullo L, Abbruscato T. Nicotine and electronic cigarette (E-Cig) exposure decreases brain glucose utilization in ischemic stroke. J Neurochem. 2018;147:204-221 pubmed publisher
Tan Z, Wang C, Li X, Guan F. Bisecting N-Acetylglucosamine Structures Inhibit Hypoxia-Induced Epithelial-Mesenchymal Transition in Breast Cancer Cells. Front Physiol. 2018;9:210 pubmed publisher
Simonetti B, Danson C, Heesom K, Cullen P. Sequence-dependent cargo recognition by SNX-BARs mediates retromer-independent transport of CI-MPR. J Cell Biol. 2017;216:3695-3712 pubmed publisher
Sowa T, Menju T, Chen Yoshikawa T, Takahashi K, Nishikawa S, Nakanishi T, et al. Hypoxia-inducible factor 1 promotes chemoresistance of lung cancer by inducing carbonic anhydrase IX expression. Cancer Med. 2017;6:288-297 pubmed publisher
Zhang L, Du J, Justus S, Hsu C, Bonet Ponce L, Wu W, et al. Reprogramming metabolism by targeting sirtuin 6 attenuates retinal degeneration. J Clin Invest. 2016;126:4659-4673 pubmed publisher
Dey J, Kerwin W, Grenley M, Casalini J, Tretyak I, Ditzler S, et al. A Platform for Rapid, Quantitative Assessment of Multiple Drug Combinations Simultaneously in Solid Tumors In Vivo. PLoS ONE. 2016;11:e0158617 pubmed publisher
Hegedus A, Kavanagh Williamson M, Huthoff H. HIV-1 pathogenicity and virion production are dependent on the metabolic phenotype of activated CD4+ T cells. Retrovirology. 2014;11:98 pubmed publisher
Eilertsen M, Andersen S, Al Saad S, Kiselev Y, Donnem T, Stenvold H, et al. Monocarboxylate transporters 1-4 in NSCLC: MCT1 is an independent prognostic marker for survival. PLoS ONE. 2014;9:e105038 pubmed publisher
Ramratnam M, Sharma R, D Auria S, Lee S, Wang D, Huang X, et al. Transgenic knockdown of cardiac sodium/glucose cotransporter 1 (SGLT1) attenuates PRKAG2 cardiomyopathy, whereas transgenic overexpression of cardiac SGLT1 causes pathologic hypertrophy and dysfunction in mice. J Am Heart Assoc. 2014;3: pubmed publisher
Muñoz Montesino C, Roa F, Pena E, Gonzalez M, Sotomayor K, Inostroza E, et al. Mitochondrial ascorbic acid transport is mediated by a low-affinity form of the sodium-coupled ascorbic acid transporter-2. Free Radic Biol Med. 2014;70:241-54 pubmed publisher
Flavahan W, Wu Q, Hitomi M, Rahim N, Kim Y, Sloan A, et al. Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake. Nat Neurosci. 2013;16:1373-82 pubmed publisher
Sorrentino N, D Orsi L, Sambri I, Nusco E, Monaco C, Spampanato C, et al. A highly secreted sulphamidase engineered to cross the blood-brain barrier corrects brain lesions of mice with mucopolysaccharidoses type IIIA. EMBO Mol Med. 2013;5:675-90 pubmed publisher
Longati P, Jia X, Eimer J, Wagman A, Witt M, Rehnmark S, et al. 3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing. BMC Cancer. 2013;13:95 pubmed publisher
Takadate T, Onogawa T, Fukuda T, Motoi F, Suzuki T, Fujii K, et al. Novel prognostic protein markers of resectable pancreatic cancer identified by coupled shotgun and targeted proteomics using formalin-fixed paraffin-embedded tissues. Int J Cancer. 2013;132:1368-82 pubmed publisher
Jang S, Han H, Jang K, Jun Y, Jang S, Min K, et al. The Glycolytic Phenotype is Correlated with Aggressiveness and Poor Prognosis in Invasive Ductal Carcinomas. J Breast Cancer. 2012;15:172-80 pubmed publisher
Mandeville H, Ng Q, Daley F, Barber P, Pierce G, Finch J, et al. Operable non-small cell lung cancer: correlation of volumetric helical dynamic contrast-enhanced CT parameters with immunohistochemical markers of tumor hypoxia. Radiology. 2012;264:581-9 pubmed publisher
Smeland E, Kilvaer T, Sorbye S, Valkov A, Andersen S, Bremnes R, et al. Prognostic impacts of hypoxic markers in soft tissue sarcoma. Sarcoma. 2012;2012:541650 pubmed publisher
Oo Z, Deng R, Hu M, Ni M, Kandasamy K, Bin Ibrahim M, et al. The performance of primary human renal cells in hollow fiber bioreactors for bioartificial kidneys. Biomaterials. 2011;32:8806-15 pubmed publisher
Merlini M, Meyer E, Ulmann Schuler A, Nitsch R. Vascular ?-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcA? mice. Acta Neuropathol. 2011;122:293-311 pubmed publisher
Mattmiller S, Corl C, Gandy J, Loor J, Sordillo L. Glucose transporter and hypoxia-associated gene expression in the mammary gland of transition dairy cattle. J Dairy Sci. 2011;94:2912-22 pubmed publisher
Jun Y, Jang S, Han H, Lee K, Jang K, Paik S. Clinicopathologic significance of GLUT1 expression and its correlation with Apaf-1 in colorectal adenocarcinomas. World J Gastroenterol. 2011;17:1866-73 pubmed publisher
Ruderisch N, Virgintino D, Makrides V, Verrey F. Differential axial localization along the mouse brain vascular tree of luminal sodium-dependent glutamine transporters Snat1 and Snat3. J Cereb Blood Flow Metab. 2011;31:1637-47 pubmed publisher
Lee Y, Kim J, Nam S, Goo J, Choi S, Choi Y, et al. Differential regulation of the biosynthesis of glucose transporters by the PI3-K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla. Int J Mol Med. 2011;27:319-27 pubmed publisher
Andersen S, Eilertsen M, Donnem T, Al Shibli K, Al Saad S, Busund L, et al. Diverging prognostic impacts of hypoxic markers according to NSCLC histology. Lung Cancer. 2011;72:294-302 pubmed publisher
Xiao C, Kim H, Lahusen T, Wang R, Xu X, Gavrilova O, et al. SIRT6 deficiency results in severe hypoglycemia by enhancing both basal and insulin-stimulated glucose uptake in mice. J Biol Chem. 2010;285:36776-84 pubmed publisher
Hasselbalch B, Eriksen J, Broholm H, Christensen I, Grunnet K, Horsman M, et al. Prospective evaluation of angiogenic, hypoxic and EGFR-related biomarkers in recurrent glioblastoma multiforme treated with cetuximab, bevacizumab and irinotecan. APMIS. 2010;118:585-94 pubmed publisher
Banerjee S, Wang D, Alzamora R, Huang X, PASTOR SOLER N, Hallows K, et al. SGLT1, a novel cardiac glucose transporter, mediates increased glucose uptake in PRKAG2 cardiomyopathy. J Mol Cell Cardiol. 2010;49:683-92 pubmed publisher
Svensson K, Welch J, Kucharzewska P, Bengtson P, Bjurberg M, Påhlman S, et al. Hypoxia-mediated induction of the polyamine system provides opportunities for tumor growth inhibition by combined targeting of vascular endothelial growth factor and ornithine decarboxylase. Cancer Res. 2008;68:9291-301 pubmed publisher
Khan Z, Boscolo E, Picard A, Psutka S, Melero Martin J, Bartch T, et al. Multipotential stem cells recapitulate human infantile hemangioma in immunodeficient mice. J Clin Invest. 2008;118:2592-9 pubmed publisher
product information
Catalog Number :
ab40084
Product Name :
Glucose Transporter GLUT1 antibody [SPM498]
Host Species :
Mouse
Clonality :
monoclonal
Product Type :
Primary antibodies
Size :
500 ul
SwissProtID :
P11166
Isotype :
IgG2a
CrossReactivity :
Reacts with: Human, Mouse, Rat.
Application Summary :
Flow Cyt, ICC/IF, IHC-Fr, IHC-P, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK