This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Ascent Scientific
product type :
antibody
product name :
GLP1R antibody
catalog :
ab39072
quantity :
100 ug
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat, dog, pig
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 20
Published Application/Species/DilutionReference
  • immunocytochemistry; rat; 1:100; fig 3
  • western blot; rat; 1:1000; fig 3
Zhang H, Xiong Z, Wang J, Zhang S, Lei L, Yang L, et al. Glucagon-like peptide-1 protects cardiomyocytes from advanced oxidation protein product-induced apoptosis via the PI3K/Akt/Bad signaling pathway. Mol Med Rep. 2016;13:1593-601 pubmed publisher
  • western blot; human
  • immunocytochemistry; human
Kim D, Park M, Choi J, Lim S, Choi H, Park S. Hyperglycemia-induced GLP-1R downregulation causes RPE cell apoptosis. Int J Biochem Cell Biol. 2015;59:41-51 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:100
Oh T, Shin J, Kang G, Park K, Cho Y. Effect of the combination of metformin and fenofibrate on glucose homeostasis in diabetic Goto-Kakizaki rats. Exp Mol Med. 2013;45:e30 pubmed publisher
  • immunohistochemistry - frozen section; pig; 1:25
  • western blot; pig
Moberly S, Mather K, Berwick Z, Owen M, Goodwill A, Casalini E, et al. Impaired cardiometabolic responses to glucagon-like peptide 1 in obesity and type 2 diabetes mellitus. Basic Res Cardiol. 2013;108:365 pubmed publisher
Lietzau G, Nystrom T, Ostenson C, Darsalia V, Patrone C. Type 2 diabetes-induced neuronal pathology in the piriform cortex of the rat is reversed by the GLP-1 receptor agonist exendin-4. Oncotarget. 2016;7:5865-76 pubmed publisher
He J, Wang C, Sun Y, Lu B, Cui J, Dong N, et al. Exendin-4 protects bone marrow-derived mesenchymal stem cells against oxygen/glucose and serum deprivation-induced apoptosis through the activation of the cAMP/PKA signaling pathway and the attenuation of ER stress. Int J Mol Med. 2016;37:889-900 pubmed publisher
Zhao X, Liu G, Shen H, Gao B, Li X, Fu J, et al. Liraglutide inhibits autophagy and apoptosis induced by high glucose through GLP-1R in renal tubular epithelial cells. Int J Mol Med. 2015;35:684-92 pubmed publisher
Yao D, Yang L, Wang Y, Liu C, Wei Y, Jia X, et al. Geniposide promotes beta-cell regeneration and survival through regulating β-catenin/TCF7L2 pathway. Cell Death Dis. 2015;6:e1746 pubmed publisher
Nomiyama T, Kawanami T, Irie S, Hamaguchi Y, Terawaki Y, Murase K, et al. Exendin-4, a GLP-1 receptor agonist, attenuates prostate cancer growth. Diabetes. 2014;63:3891-905 pubmed publisher
Gong N, Fan H, Ma A, Xiao Q, Wang Y. Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors. Neuropharmacology. 2014;84:31-45 pubmed publisher
Gong N, Xiao Q, Zhu B, Zhang C, Wang Y, Fan H, et al. Activation of spinal glucagon-like peptide-1 receptors specifically suppresses pain hypersensitivity. J Neurosci. 2014;34:5322-34 pubmed publisher
Zhu B, Gong N, Fan H, Peng C, Ding X, Jiang Y, et al. Lamiophlomis rotata, an orally available Tibetan herbal painkiller, specifically reduces pain hypersensitivity states through the activation of spinal glucagon-like peptide-1 receptors. Anesthesiology. 2014;121:835-51 pubmed publisher
Moberly S, Berwick Z, Kohr M, Svendsen M, Mather K, Tune J. Intracoronary glucagon-like peptide 1 preferentially augments glucose uptake in ischemic myocardium independent of changes in coronary flow. Exp Biol Med (Maywood). 2012;237:334-42 pubmed publisher
Yang H, Li H, Wang Z, Shi Y, Jiang G, Zeng F. Exendin-4 ameliorates renal ischemia-reperfusion injury in the rat. J Surg Res. 2013;185:825-32 pubmed publisher
Sonoda N, Imamura T, Yoshizaki T, Babendure J, Lu J, Olefsky J. Beta-Arrestin-1 mediates glucagon-like peptide-1 signaling to insulin secretion in cultured pancreatic beta cells. Proc Natl Acad Sci U S A. 2008;105:6614-9 pubmed publisher
Chaykovska L, Alter M, von Websky K, Hohmann M, Tsuprykov O, Reichetzeder C, et al. Effects of telmisartan and linagliptin when used in combination on blood pressure and oxidative stress in rats with 2-kidney-1-clip hypertension. J Hypertens. 2013;31:2290-8; discussion 2299 pubmed publisher
Panjwani N, Mulvihill E, Longuet C, Yusta B, Campbell J, Brown T, et al. GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE(-/-) mice. Endocrinology. 2013;154:127-39 pubmed publisher
Gier B, Butler P, Lai C, Kirakossian D, Denicola M, Yeh M. Glucagon like peptide-1 receptor expression in the human thyroid gland. J Clin Endocrinol Metab. 2012;97:121-31 pubmed publisher
Romaní-Pérez M, Outeiriño-Iglesias V, Gil-Lozano M, Gonzalez-Matias L, Mallo F, Vigo E. Pulmonary GLP-1 receptor increases at birth and exogenous GLP-1 receptor agonists augmented surfactant-protein levels in litters from normal and nitrofen-treated pregnant rats. Endocrinology. 2013;154:1144-55 pubmed publisher
Gupta N, Mells J, Dunham R, Grakoui A, Handy J, Saxena N, et al. Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway. Hepatology. 2010;51:1584-92 pubmed publisher
product information
Catalog Number :
ab39072
Product Name :
GLP1R antibody
Host Species :
Rabbit
Clonality :
polyclonal
Product Type :
Primary antibodies
Size :
100 ug
SwissProtID :
Q2M229
Isotype :
IgG
CrossReactivity :
Reacts with: Human, Mouse, Rat, Dog. Predicted to react with: Sheep.
Application Summary :
IHC-P, WB
company information
Abcam
330 Cambridge Science Park
Cambridge
CB4 0FL UK
orders@abcam.com
44 (0)1223 696000

1 Kendall Square, Ste 341
Cambridge, MA 02139-1517
USA
us.orders@abcam.com
617 225 2272, 888-77-ABCAM (22226)

www.abcam.com
888-7722226
headquarters: UK