This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Ascent Scientific
product type :
antibody
product name :
Rabbit polyclonal to KMT6 / EZH2 - ChIP Grade
catalog :
ab3748
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, zebrafish , common platanna
application :
western blot, immunocytochemistry, chromatin immunoprecipitation, immunohistochemistry - paraffin section, RNA immunoprecipitation
citations: 17
Published Application/Species/DilutionReference
  • RNA immunoprecipitation; human; fig 3
G Hendrickson D, Kelley D, Tenen D, BERNSTEIN B, Rinn J. Widespread RNA binding by chromatin-associated proteins. Genome Biol. 2016;17:28 pubmed publisher
  • western blot; human; fig 9
Zhang Z, Zhao G, Zhuang C, Shen Y, Zhao W, Xu J, et al. Long non-coding RNA LINC00628 functions as a gastric cancer suppressor via long-range modulating the expression of cell cycle related genes. Sci Rep. 2016;6:27435 pubmed publisher
  • chromatin immunoprecipitation; human; fig 5
Park S, Shim J, Park H, Eum D, Park M, Mi Yi J, et al. MacroH2A1 downregulation enhances the stem-like properties of bladder cancer cells by transactivation of Lin28B. Oncogene. 2016;35:1292-301 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; fig 5
Hatanaka Y, Inoue K, Oikawa M, Kamimura S, Ogonuki N, Kodama E, et al. Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposons. Proc Natl Acad Sci U S A. 2015;112:14641-6 pubmed publisher
  • western blot; mouse; 1:2000; fig 2
Gasque Schoof C, Izzotti A, Jasiulionis M, Vasques L. The Roles of miR-26, miR-29, and miR-203 in the Silencing of the Epigenetic Machinery during Melanocyte Transformation. Biomed Res Int. 2015;2015:634749 pubmed publisher
  • chromatin immunoprecipitation; human; fig 4c
Wang Y, Zhong H, Xie X, Chen C, Huang D, Shen L, et al. Long noncoding RNA derived from CD244 signaling epigenetically controls CD8+ T-cell immune responses in tuberculosis infection. Proc Natl Acad Sci U S A. 2015;112:E3883-92 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:150
McLaughlin N, Wang F, Saifudeen Z, El-Dahr S. In situ histone landscape of nephrogenesis. Epigenetics. 2014;9:222-35 pubmed publisher
  • chromatin immunoprecipitation; human
Bengani H, Mendiratta S, Maini J, Vasanthi D, Sultana H, Ghasemi M, et al. Identification and Validation of a Putative Polycomb Responsive Element in the Human Genome. PLoS ONE. 2013;8:e67217 pubmed
  • immunocytochemistry; human
Martin N, Popov N, Aguilo F, O'Loghlen A, Raguz S, Snijders A, et al. Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK⁴a regulation. EMBO J. 2013;32:982-95 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500
Wu Z, Wang Q, Wang L, Li G, Liu H, Fan F, et al. Combined aberrant expression of Bmi1 and EZH2 is predictive of poor prognosis in glioma patients. J Neurol Sci. 2013;335:191-6 pubmed publisher
Hu J, Song W, Zhang S, Shen X, Qiu X, Wu H, et al. HBx-upregulated lncRNA UCA1 promotes cell growth and tumorigenesis by recruiting EZH2 and repressing p27Kip1/CDK2 signaling. Sci Rep. 2016;6:23521 pubmed publisher
Huang J, Zhou L, Chen H, Wu C, Duo Z, Zhang Y. EZH2 is overexpressed in laryngeal squamous cell carcinoma and enhances the stem-like properties of AMC-HN-8 cells. Oncol Lett. 2016;12:837-846 pubmed
Kim H, Kang K, Ekram M, Roh T, Kim J. Aebp2 as an epigenetic regulator for neural crest cells. PLoS ONE. 2011;6:e25174 pubmed publisher
Postberg J, Heyse K, Cremer M, Cremer T, Lipps H. Spatial and temporal plasticity of chromatin during programmed DNA-reorganization in Stylonychia macronuclear development. Epigenetics Chromatin. 2008;1:3 pubmed publisher
Lin C, Lin C, Tanaka H, Fero M, Eisenman R. Gene regulation and epigenetic remodeling in murine embryonic stem cells by c-Myc. PLoS ONE. 2009;4:e7839 pubmed publisher
Tao Y, Liu S, Briones V, Geiman T, Muegge K. Treatment of breast cancer cells with DNA demethylating agents leads to a release of Pol II stalling at genes with DNA-hypermethylated regions upstream of TSS. Nucleic Acids Res. 2011;39:9508-20 pubmed publisher
Beckedorff F, Ayupe A, Crocci-Souza R, Amaral M, Nakaya H, Soltys D, et al. The intronic long noncoding RNA ANRASSF1 recruits PRC2 to the RASSF1A promoter, reducing the expression of RASSF1A and increasing cell proliferation. PLoS Genet. 2013;9:e1003705 pubmed publisher
company information
Abcam
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Cambridge
CB4 0FL UK
orders@abcam.com
44 (0)1223 696000

1 Kendall Square, Ste 341
Cambridge, MA 02139-1517
USA
us.orders@abcam.com
617 225 2272, 888-77-ABCAM (22226)

www.abcam.com
888-7722226
headquarters: UK