This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-MMP2 antibody
catalog :
ab37150
quantity :
100 µl
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 61
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 5e
Lackie R, Marques Lopes J, Ostapchenko V, Good S, Choy W, van Oosten Hawle P, et al. Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer's disease. Acta Neuropathol Commun. 2020;8:143 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 6b
Kang K, Lee S, Kim J, Lee B, Kim S, Park Y, et al. Etoposide-mediated interleukin-8 secretion from bone marrow stromal cells induces hematopoietic stem cell mobilization. BMC Cancer. 2020;20:619 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig s1c
  • western blot; mouse; 1:1000; loading ...; fig 2k
Song H, Xu T, Feng X, Lai Y, Yang Y, Zheng H, et al. Itaconate prevents abdominal aortic aneurysm formation through inhibiting inflammation via activation of Nrf2. EBioMedicine. 2020;57:102832 pubmed publisher
  • western blot; human; loading ...; fig 7e
Tian S, Peng P, Li J, Deng H, Zhan N, Zeng Z, et al. SERPINH1 regulates EMT and gastric cancer metastasis via the Wnt/β-catenin signaling pathway. Aging (Albany NY). 2020;12:3574-3593 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2k
Cai H, Li J, Zhang Y, Liao Y, Zhu Y, Wang C, et al. LDHA Promotes Oral Squamous Cell Carcinoma Progression Through Facilitating Glycolysis and Epithelial-Mesenchymal Transition. Front Oncol. 2019;9:1446 pubmed publisher
  • western blot; human; loading ...; fig 2c
Yang X, Jiang J, Zhang C, Li Y. Baicalein restrains proliferation, migration, and invasion of human malignant melanoma cells by down-regulating colon cancer associated transcript-1. Braz J Med Biol Res. 2019;52:e8934 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 5e
Yang Y, Tang F, Wei F, Yang L, Kuang C, Zhang H, et al. Silencing of long non-coding RNA H19 downregulates CTCF to protect against atherosclerosis by upregulating PKD1 expression in ApoE knockout mice. Aging (Albany NY). 2019;11:10016-10030 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:800; loading ...; fig 7a
Dosh R, Jordan Mahy N, Sammon C, Le Maitre C. Interleukin 1 is a key driver of inflammatory bowel disease-demonstration in a murine IL-1Ra knockout model. Oncotarget. 2019;10:3559-3575 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 1a
He S, Nian F, Chen W, Yin L, Auchoybur M, Tao Z, et al. I-κB kinase-ε knockout protects against angiotensin II induced aortic valve thickening in apolipoprotein E deficient mice. Biomed Pharmacother. 2019;109:1287-1295 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:2500; fig s3071882
Rickelt S, Hynes R. Antibodies and methods for immunohistochemistry of extracellular matrix proteins. Matrix Biol. 2018;71-72:10-27 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 6c
Jin L, Lu J, Gao J. Silencing SUMO2 promotes protection against degradation and apoptosis of nucleus pulposus cells through p53 signaling pathway in intervertebral disc degeneration. Biosci Rep. 2018;38: pubmed publisher
  • immunohistochemistry; rat; fig 1a
  • western blot; rat; fig 1b
Rempe R, Hartz A, Soldner E, Sokola B, Alluri S, Abner E, et al. Matrix Metalloproteinase-Mediated Blood-Brain Barrier Dysfunction in Epilepsy. J Neurosci. 2018;38:4301-4315 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig s3b
Yang L, Shen L, Gao P, Li G, He Y, Wang M, et al. Effect of AMPK signal pathway on pathogenesis of abdominal aortic aneurysms. Oncotarget. 2017;8:92827-92840 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig 9d
  • western blot; human; 1:1000; loading ...; fig 2e
Lu J, Yang Y, Guo G, Liu Y, Zhang Z, Dong S, et al. IKBKE regulates cell proliferation and epithelial-mesenchymal transition of human malignant glioma via the Hippo pathway. Oncotarget. 2017;8:49502-49514 pubmed publisher
  • western blot; mouse; loading ...; fig 2e
He Y, Wang X, Zhang J, Liu Z, Pan W, Shen Y, et al. Association of Serum HMGB2 Levels With In-Stent Restenosis: HMGB2 Promotes Neointimal Hyperplasia in Mice With Femoral Artery Injury and Proliferation and Migration of VSMCs. Arterioscler Thromb Vasc Biol. 2017;37:717-729 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 6a
Liu L, Guan H, Li Y, Ying Z, Wu J, Zhu X, et al. Astrocyte Elevated Gene 1 Interacts with Acetyltransferase p300 and c-Jun To Promote Tumor Aggressiveness. Mol Cell Biol. 2017;37: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3a
Hou H, Chen L, Zha Z, Cai S, Tan M, Guo G, et al. Long form collapsin response mediator protein-1 promotes the migration and invasion of osteosarcoma cells. Oncol Lett. 2016;12:23-28 pubmed
  • western blot; human; fig 10
Lehner C, Gehwolf R, Ek J, Korntner S, Bauer H, Bauer H, et al. The blood-tendon barrier: identification and characterisation of a novel tissue barrier in tendon blood vessels. Eur Cell Mater. 2016;31:296-311 pubmed
  • western blot; rat; 1:500; fig 5
Zhou N, Zhu Y, Zhang P, Zhang Y, Zhou M, Wang T, et al. Imperatorin derivative OW1 inhibits the upregulation of TGF-? and MMP-2 in renovascular hypertension-induced cardiac remodeling. Exp Ther Med. 2016;11:1748-1754 pubmed
  • western blot; human; 1:1000; loading ...; fig 5b
Alonso F, Domingos Pereira S, Le Gal L, Derré L, Meda P, Jichlinski P, et al. Targeting endothelial connexin40 inhibits tumor growth by reducing angiogenesis and improving vessel perfusion. Oncotarget. 2016;7:14015-28 pubmed publisher
  • immunohistochemistry; human; 1.25 ug/ml
Wardill H, Logan R, Bowen J, Van Sebille Y, Gibson R. Tight junction defects are seen in the buccal mucosa of patients receiving standard dose chemotherapy for cancer. Support Care Cancer. 2016;24:1779-88 pubmed publisher
Wang Y, Zhang L, Wei N, Sun Y, Pan W, Chen Y. Silencing LINC00482 inhibits tumor-associated inflammation and angiogenesis through down-regulation of MMP-15 via FOXA1 in bladder cancer. Aging (Albany NY). 2020;13:2264-2278 pubmed publisher
Yuan Y, Wang J, Xu M, Zhang Y, Wang Z, Liang L, et al. 20(S)-ginsenoside Rh2 as agent for the treatment of LMN-CRC via regulating epithelial-mesenchymal transition. Biosci Rep. 2020;40: pubmed publisher
Zhao S, Wang J, Cao Z, Gao L, Zheng Y, Wang J, et al. miR-126a-3p induces proliferation, migration and invasion of trophoblast cells in pre-eclampsia-like rats by inhibiting A Disintegrin and Metalloprotease 9. Biosci Rep. 2019;39: pubmed publisher
Wang W, Zhang L, Gao W, Zhang D, Zhao Z, Bao Y. miR‑489 promotes apoptosis and inhibits invasiveness of glioma cells by targeting PAK5/RAF1 signaling pathways. Oncol Rep. 2019;42:2390-2401 pubmed publisher
Bi Y, Fu Y, Wang S, Chen X, Cai X. Schizandrin A exerts anti-tumor effects on A375 cells by down-regulating H19. Braz J Med Biol Res. 2019;52:e8385 pubmed publisher
Jian Y, Xu C, Li Y, Tang B, Xie S, Zeng E. Down-regulated microRNA-30b-3p inhibits proliferation, invasion and migration of glioma cells via inactivation of the AKT signaling pathway by up-regulating RECK. Biosci Rep. 2019;39: pubmed publisher
Dong S, Zhang X, Liu D. Overexpression of long noncoding RNA GAS5 suppresses tumorigenesis and development of gastric cancer by sponging miR-106a-5p through the Akt/mTOR pathway. Biol Open. 2019;: pubmed publisher
Xu J, Wang H, Wang H, Chen Q, Zhang L, Song C, et al. The inhibition of miR-126 in cell migration and invasion of cervical cancer through regulating ZEB1. Hereditas. 2019;156:11 pubmed publisher
He C, Chen Z, Li Y, Yang Z, Zeng F, Cui Y, et al. miR-10b suppresses cell invasion and metastasis through targeting HOXA3 regulated by FAK/YAP signaling pathway in clear-cell renal cell carcinoma. BMC Nephrol. 2019;20:127 pubmed publisher
Sun L, Jin X, Xie L, Xu G, Cui Y, Chen Z. Swainsonine represses glioma cell proliferation, migration and invasion by reduction of miR-92a expression. BMC Cancer. 2019;19:247 pubmed publisher
Sui H, Lou A, Li Z, Yang J. Lidocaine inhibits growth, migration and invasion of gastric carcinoma cells by up-regulation of miR-145. BMC Cancer. 2019;19:233 pubmed publisher
Liao Z, Zhang H, Fan P, Huang Q, Dong K, Qi Y, et al. High PLK4 expression promotes tumor progression and induces epithelial‑mesenchymal transition by regulating the Wnt/β‑catenin signaling pathway in colorectal cancer. Int J Oncol. 2019;54:479-490 pubmed publisher
Cortés E, Lachowski D, Robinson B, Sarper M, Teppo J, Thorpe S, et al. Tamoxifen mechanically reprograms the tumor microenvironment via HIF-1A and reduces cancer cell survival. EMBO Rep. 2019;20: pubmed publisher
Liu S, Maguire E, Bai Y, Huang L, Liu Y, Xu L, et al. A Novel Regulatory Axis, CHD1L-MicroRNA 486-Matrix Metalloproteinase 2, Controls Spermatogonial Stem Cell Properties. Mol Cell Biol. 2019;39: pubmed publisher
Xu Y, Yang X, Gao D, Yang L, Miskimins K, Qian S. Dihomo-γ-linolenic acid inhibits xenograft tumor growth in mice bearing shRNA-transfected HCA-7 cells targeting delta-5-desaturase. BMC Cancer. 2018;18:1268 pubmed publisher
Yao J, Zhang X, Li J, Zhao D, Gao B, Zhou H, et al. Silencing TRIP13 inhibits cell growth and metastasis of hepatocellular carcinoma by activating of TGF-β1/smad3. Cancer Cell Int. 2018;18:208 pubmed publisher
Jin Z, Li H, Hong X, Ying G, Lu X, Zhuang L, et al. TRIM14 promotes colorectal cancer cell migration and invasion through the SPHK1/STAT3 pathway. Cancer Cell Int. 2018;18:202 pubmed publisher
Li Y, Sun W, Han N, Zou Y, Yin D. Curcumin inhibits proliferation, migration, invasion and promotes apoptosis of retinoblastoma cell lines through modulation of miR-99a and JAK/STAT pathway. BMC Cancer. 2018;18:1230 pubmed publisher
Obr A, Kumar S, Chang Y, Bulatowicz J, Barnes B, Birge R, et al. Insulin-like growth factor receptor signaling in breast tumor epithelium protects cells from endoplasmic reticulum stress and regulates the tumor microenvironment. Breast Cancer Res. 2018;20:138 pubmed publisher
Seifert R, Kuhlmann M, Eligehausen S, Kiefer F, Hermann S, Schäfers M. Molecular imaging of MMP activity discriminates unstable from stable plaque phenotypes in shear-stress induced murine atherosclerosis. PLoS ONE. 2018;13:e0204305 pubmed publisher
Huang D, Bi C, Zhao Q, Ding X, Bian C, Wang H, et al. Knockdown long non-coding RNA ANRIL inhibits proliferation, migration and invasion of HepG2 cells by down-regulation of miR-191. BMC Cancer. 2018;18:919 pubmed publisher
Lopez Charcas O, Espinosa A, Alfaro A, Herrera Carrillo Z, Ramírez Cordero B, Cortes Reynosa P, et al. The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity. Sci Rep. 2018;8:12995 pubmed publisher
Zhu H, Dai R, Zhou Y, Fu H, Meng Q. TLR2 Ligand Pam3CSK4 Regulates MMP-2/9 Expression by MAPK/NF-κB Signaling Pathways in Primary Brain Microvascular Endothelial Cells. Neurochem Res. 2018;43:1897-1904 pubmed publisher
Qiu J, Zhang Y, Chen H, Guo Z. MicroRNA-488 inhibits proliferation, invasion and EMT in osteosarcoma cell lines by targeting aquaporin 3. Int J Oncol. 2018;53:1493-1504 pubmed publisher
Wang L, Liu M, Yin G, Li N, Wang D. Exogenous Tissue Inhibitor of Metalloproteinase-2 Affects Matrix Metalloproteinase-2 Expression in Conjunctival Filtering Blebs and Bleb Scarring in Rats. Biomed Res Int. 2018;2018:9365950 pubmed publisher
Ding R, Liu X, Xiang Y, Zhang Y, Zhang J, Guo F, et al. Altered Matrix Metalloproteinases Expression in Placenta from Patients with Gestational Diabetes Mellitus. Chin Med J (Engl). 2018;131:1255-1258 pubmed publisher
Liu Y, Wang Y, Yao D, Cui D. LncSOX4 serves an oncogenic role in the tumorigenesis of epithelial ovarian cancer by promoting cell proliferation and inhibiting apoptosis. Mol Med Rep. 2018;17:8282-8288 pubmed publisher
Ding N, Sun X, Wang T, Huang L, Wen J, Zhou Y. miR‑378a‑3p exerts tumor suppressive function on the tumorigenesis of esophageal squamous cell carcinoma by targeting Rab10. Int J Mol Med. 2018;42:381-391 pubmed publisher
Zhou M, Ding Y, Cai L, Wang Y, Lin C, Shi Z. Low molecular weight fucoidan attenuates experimental abdominal aortic aneurysm through interfering the leukocyte-endothelial cells interaction. Mol Med Rep. 2018;17:7089-7096 pubmed publisher
Du Q, Liu J, Zhang X, Zhang X, Zhu H, Wei M, et al. Propofol inhibits proliferation, migration, and invasion but promotes apoptosis by regulation of Sox4 in endometrial cancer cells. Braz J Med Biol Res. 2018;51:e6803 pubmed publisher
Li T, Yi L, Hai L, Ma H, Tao Z, Zhang C, et al. The interactome and spatial redistribution feature of Ca2+ receptor protein calmodulin reveals a novel role in invadopodia-mediated invasion. Cell Death Dis. 2018;9:292 pubmed publisher
Wang L, Wang D, Liu M, Yao R. Correlation between Tissue Characterization and Dynamic Expression of Matrix Metalloproteinase-2 and Its Tissue Inhibitor in Conjunctival Filtering Bleb of Rats. Biomed Res Int. 2017;2017:1054129 pubmed publisher
Wei C, Kong Y, Hua X, Li G, Zheng S, Cheng M, et al. NAD replenishment with nicotinamide mononucleotide protects blood-brain barrier integrity and attenuates delayed tissue plasminogen activator-induced haemorrhagic transformation after cerebral ischaemia. Br J Pharmacol. 2017;174:3823-3836 pubmed publisher
Iizuka Hishikawa Y, Hishikawa D, Sasaki J, Takubo K, Goto M, Nagata K, et al. Lysophosphatidic acid acyltransferase 3 tunes the membrane status of germ cells by incorporating docosahexaenoic acid during spermatogenesis. J Biol Chem. 2017;292:12065-12076 pubmed publisher
Jiang W, Zhang Z, Yang H, Lin Q, Han C, Qin X. The Involvement of miR-29b-3p in Arterial Calcification by Targeting Matrix Metalloproteinase-2. Biomed Res Int. 2017;2017:6713606 pubmed publisher
Sun B, Pei B, Zhang K, Zhang L, Zhang G, Liu J, et al. Significance of interstitial tumor-associated macrophages in the progression of lung adenocarcinoma. Oncol Lett. 2016;12:4467-4476 pubmed publisher
Patel R, Moffatt J, Mourmoura E, Demaison L, Seed P, Poston L, et al. Effect of reproductive ageing on pregnant mouse uterus and cervix. J Physiol. 2017;595:2065-2084 pubmed publisher
Lin Y, Jean Y, Lee H, Lin S, Pan C, Chen W, et al. Excavatolide B Attenuates Rheumatoid Arthritis through the Inhibition of Osteoclastogenesis. Mar Drugs. 2017;15: pubmed publisher
Murawski M, Wozniak M, Duś Szachniewicz K, Kołodziej P, Rzeszutko M, Ziółkowski P. Significance of Matrix Metalloproteinase 9 Expression as Supporting Marker to Cytokeratin 19 mRNA in Sentinel Lymph Nodes in Breast Cancer Patients. Int J Mol Sci. 2016;17: pubmed publisher
Tian F, Cheng Y, Li X, Wang F, Qin C, Ma X, et al. The YY1/MMP2 axis promotes trophoblast invasion at the maternal-fetal interface. J Pathol. 2016;239:36-47 pubmed publisher
product information
CatalogNumber :
ab37150
ItemName :
Anti-MMP2 antibody
Product Type :
Primary Antibodies
Host Species :
Rabbit
Clonality :
Polyclonal
Conjugate :
Not Conjugated
Antigen Modification :
No Modifications
Size :
100 µl
SpeciesSummary :
Chk, Hu, Ms, Rat
Uses :
ICC/IF, IHC-Fr, IHC-P, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK