product summary
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company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-Aggrecan antibody
catalog :
ab36861
quantity :
100 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 17
Published Application/Species/Sample/DilutionReference
  • western blot; rat; loading ...; fig 1c
Huang X, Ni B, Xi Y, Chu X, Zhang R, You H. Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis. Aging (Albany NY). 2019;11:12532-12545 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 4b
Yang H, Zhang M, Liu Q, Zhang H, Zhang J, Lu L, et al. Inhibition of Ihh Reverses Temporomandibular Joint Osteoarthritis via a PTH1R Signaling Dependent Mechanism. Int J Mol Sci. 2019;20: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 2f, 3c
Ji Q, Xu X, Kang L, Xu Y, Xiao J, Goodman S, et al. Hematopoietic PBX-interacting protein mediates cartilage degeneration during the pathogenesis of osteoarthritis. Nat Commun. 2019;10:313 pubmed publisher
  • immunohistochemistry; rat; 1:200; fig 7
  • western blot; rat; 1:500; fig 3
Jiao K, Zeng G, Niu L, Yang H, Ren G, Xu X, et al. Activation of ?2A-adrenergic signal transduction in chondrocytes promotes degenerative remodelling of temporomandibular joint. Sci Rep. 2016;6:30085 pubmed publisher
Guo Z, Wang H, Zhao F, Liu M, Wang F, Kang M, et al. Exosomal circ-BRWD1 contributes to osteoarthritis development through the modulation of miR-1277/TRAF6 axis. Arthritis Res Ther. 2021;23:159 pubmed publisher
Chen Z, Zhang W, Deng M, Li Y, Zhou Y. CircGLCE alleviates intervertebral disc degeneration by regulating apoptosis and matrix degradation through the targeting of miR-587/STAP1. Aging (Albany NY). 2020;12:21971-21991 pubmed publisher
Lei C, Colangelo D, Patil P, Li V, Ngo K, Wang D, et al. Influences of circulatory factors on intervertebral disc aging phenotype. Aging (Albany NY). 2020;12:12285-12304 pubmed publisher
Bao J, Chen Z, Xu L, Wu L, Xiong Y. Rapamycin protects chondrocytes against IL-18-induced apoptosis and ameliorates rat osteoarthritis. Aging (Albany NY). 2020;12:5152-5167 pubmed publisher
Wang A, Hu N, Zhang Y, Chen Y, Su C, Lv Y, et al. MEG3 promotes proliferation and inhibits apoptosis in osteoarthritis chondrocytes by miR-361-5p/FOXO1 axis. BMC Med Genomics. 2019;12:201 pubmed publisher
Xu S, Wu X. miR-134 inhibits chondrogenic differentiation of bone marrow mesenchymal stem cells by targetting SMAD6. Biosci Rep. 2019;39: pubmed publisher
Ji M, Jiang H, Zhang X, Shi P, Li C, Wu H, et al. Preclinical development of a microRNA-based therapy for intervertebral disc degeneration. Nat Commun. 2018;9:5051 pubmed publisher
Kong L, Sun M, Jiang Z, Li L, Lu B. MicroRNA-194 Inhibits Lipopolysaccharide-Induced Inflammatory Response in Nucleus Pulposus Cells of the Intervertebral Disc by Targeting TNF Receptor-Associated Factor 6 (TRAF6). Med Sci Monit. 2018;24:3056-3067 pubmed publisher
Suna G, Wojakowski W, Lynch M, Barallobre Barreiro J, Yin X, Mayr U, et al. Extracellular Matrix Proteomics Reveals Interplay of Aggrecan and Aggrecanases in Vascular Remodeling of Stented Coronary Arteries. Circulation. 2018;137:166-183 pubmed publisher
Ngo K, Pohl P, Wang D, Leme A, Lee J, Di P, et al. ADAMTS5 Deficiency Protects Mice From Chronic Tobacco Smoking-induced Intervertebral Disc Degeneration. Spine (Phila Pa 1976). 2017;42:1521-1528 pubmed publisher
Ma D, Kou X, Jin J, Xu T, Wu M, Deng L, et al. Hydrostatic Compress Force Enhances the Viability and Decreases the Apoptosis of Condylar Chondrocytes through Integrin-FAK-ERK/PI3K Pathway. Int J Mol Sci. 2016;17: pubmed
Liang W, Li X, Chen H, Shao X, Lin X, Shen J, et al. Expressing human SHOX in Shox2SHOX KI/KI mice leads to congenital osteoarthritis?like disease of the temporomandibular joint in postnatal mice. Mol Med Rep. 2016;14:3676-82 pubmed publisher
Hwang P, Jing L, Chen J, Lim F, Tang R, Choi H, et al. N-cadherin is Key to Expression of the Nucleus Pulposus Cell Phenotype under Selective Substrate Culture Conditions. Sci Rep. 2016;6:28038 pubmed publisher
product information
CatalogNumber :
ab36861
ItemName :
Anti-Aggrecan antibody
Product Type :
Primary Antibodies
Host Species :
Rabbit
Clonality :
Polyclonal
Conjugate :
Not Conjugated
Antigen Modification :
No Modifications
Size :
100 µg
SpeciesSummary :
Hu, Rat
Uses :
ICC/IF, IHC-P, WB
Size Note :
Other sizes available: 100 µl,200 µl
more info or order :
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK