This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-TGF beta 2 antibody
catalog :
ab36495
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 23
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 1c
Escasany E, Lanzón B, García Carrasco A, Izquierdo Lahuerta A, Torres L, Corrales P, et al. Transforming growth factor β3 deficiency promotes defective lipid metabolism and fibrosis in murine kidney. Dis Model Mech. 2021;14: pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 3a, s6b
Sharma N, Hans C. Interleukin 12p40 Deficiency Promotes Abdominal Aortic Aneurysm by Activating CCN2/MMP2 Pathways. J Am Heart Assoc. 2021;10:e017633 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 3e
Zhang Y, Xu J, Hua J, Liu J, Liang C, Meng Q, et al. A PD-L2-based immune marker signature helps to predict survival in resected pancreatic ductal adenocarcinoma. J Immunother Cancer. 2019;7:233 pubmed publisher
  • western blot; human; 1:100; loading ...; fig s1a
Lino Cardenas C, Kessinger C, Cheng Y, MacDonald C, Macgillivray T, Ghoshhajra B, et al. An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm. Nat Commun. 2018;9:1009 pubmed publisher
  • western blot; human; loading ...; fig 1c
Ventura E, Weller M, Burghardt I. Cutting Edge: ERK1 Mediates the Autocrine Positive Feedback Loop of TGF-? and Furin in Glioma-Initiating Cells. J Immunol. 2017;198:4569-4574 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:100; fig 5
Bryukhovetskiy I, Manzhulo I, Mischenko P, Milkina E, Dyuizen I, Bryukhovetskiy A, et al. Cancer stem cells and microglia in the processes of glioblastoma multiforme invasive growth. Oncol Lett. 2016;12:1721-1728 pubmed
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 4a
Tomann P, Paus R, Millar S, Scheidereit C, Schmidt Ullrich R. Lhx2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth. Development. 2016;143:1512-22 pubmed publisher
  • immunohistochemistry; mouse; fig 4
  • western blot; mouse; fig 4
Nishio M, Sugimachi K, Goto H, Wang J, Morikawa T, Miyachi Y, et al. Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice. Proc Natl Acad Sci U S A. 2016;113:E71-80 pubmed publisher
  • immunocytochemistry; mouse
  • immunohistochemistry; mouse
  • western blot; mouse
Swaminathan S, Oh D, Kang M, Shepard A, Pang I, Rhee D. TGF-?2-mediated ocular hypertension is attenuated in SPARC-null mice. Invest Ophthalmol Vis Sci. 2014;55:4084-97 pubmed publisher
Rayana N, Sugali C, Dai J, Peng M, Liu S, Zhang Y, et al. Using CRISPR Interference as a Therapeutic Approach to Treat TGFβ2-Induced Ocular Hypertension and Glaucoma. Invest Ophthalmol Vis Sci. 2021;62:7 pubmed publisher
Halbgebauer D, Roos J, Funcke J, Neubauer H, Hamilton B, Simon E, et al. Latent TGFβ-binding proteins regulate UCP1 expression and function via TGFβ2. Mol Metab. 2021;53:101336 pubmed publisher
Lee E, Nam Y, Kang S, Choi E, Han I, Kim J, et al. The local hypothalamic-pituitary-adrenal axis in cultured human dermal papilla cells. BMC Mol Cell Biol. 2020;21:42 pubmed publisher
Yang J, Zhang Y, Xu X, Li J, Yuan F, Bo S, et al. Transforming growth factor-β is involved in maintaining oocyte meiotic arrest by promoting natriuretic peptide type C expression in mouse granulosa cells. Cell Death Dis. 2019;10:558 pubmed publisher
Clements M, Byrne E, Camarillo Guerrero L, Cattin A, Zakka L, Ashraf A, et al. The Wound Microenvironment Reprograms Schwann Cells to Invasive Mesenchymal-like Cells to Drive Peripheral Nerve Regeneration. Neuron. 2017;96:98-114.e7 pubmed publisher
Riemenschneider M, Hirblinger M, Vollmann Zwerenz A, Hau P, Proescholdt M, Jaschinski F, et al. TGF-ß isoforms in cancer: Immunohistochemical expression and Smad-pathway-activity-analysis in thirteen major tumor types with a critical appraisal of antibody specificity and immunohistochemistry assay validity. Oncotarget. 2015;6:26770-81 pubmed publisher
Frei K, Gramatzki D, Tritschler I, Schroeder J, Espinoza L, Rushing E, et al. Transforming growth factor-β pathway activity in glioblastoma. Oncotarget. 2015;6:5963-77 pubmed
Cheng J, Koenig S, Kuivaniemi H, Garg V, Hans C. Pharmacological inhibitor of notch signaling stabilizes the progression of small abdominal aortic aneurysm in a mouse model. J Am Heart Assoc. 2014;3:e001064 pubmed publisher
Boileau C, Guo D, Hanna N, Regalado E, Detaint D, Gong L, et al. TGFB2 mutations cause familial thoracic aortic aneurysms and dissections associated with mild systemic features of Marfan syndrome. Nat Genet. 2012;44:916-21 pubmed publisher
Lee Y, Miller L, Chan X, Black M, Pang B, Ong C, et al. JMJD6 is a driver of cellular proliferation and motility and a marker of poor prognosis in breast cancer. Breast Cancer Res. 2012;14:R85 pubmed
Hulin A, Deroanne C, Lambert C, Dumont B, Castronovo V, Defraigne J, et al. Metallothionein-dependent up-regulation of TGF-?2 participates in the remodelling of the myxomatous mitral valve. Cardiovasc Res. 2012;93:480-9 pubmed publisher
Pocsfalvi G, Votta G, De Vincenzo A, Fiume I, Raj D, Marra G, et al. Analysis of secretome changes uncovers an autocrine/paracrine component in the modulation of cell proliferation and motility by c-Myc. J Proteome Res. 2011;10:5326-37 pubmed publisher
Bauer M, Su G, Casper C, He R, Rehrauer W, Friedl A. Heterogeneity of gene expression in stromal fibroblasts of human breast carcinomas and normal breast. Oncogene. 2010;29:1732-40 pubmed publisher
Polak M, Borthwick N, Gabriel F, Johnson P, Higgins B, Hurren J, et al. Mechanisms of local immunosuppression in cutaneous melanoma. Br J Cancer. 2007;96:1879-87 pubmed
product information
CatalogNumber :
ab36495
ItemName :
Anti-TGF beta 2 antibody
Category :
Antibody
Host :
Mouse
Clonality :
Monoclonal
Conjugate :
Unconjugated
Size :
100 µg
SpeciesSummary :
Cow, Hu, Ms
Application Summary :
ICC/IF, IHC-Fr, IHC-P, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK