This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-P Glycoprotein antibody [JSB-1]
catalog :
ab3366
quantity :
250 µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
JSB-1
reactivity :
African green monkey, human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, western blot knockout validation, immunohistochemistry knockout validation
citations: 27
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; loading ...
  • western blot knockout validation; mouse; loading ...
Vita S, Redell J, Maynard M, Zhao J, Grill R, Dash P, et al. P-glycoprotein Expression Is Upregulated in a Pre-Clinical Model of Traumatic Brain Injury. Neurotrauma Rep. 2020;1:207-217 pubmed publisher
  • immunohistochemistry knockout validation; mouse; 1:20; fig 2
  • immunohistochemistry - paraffin section; human; fig 2
  • immunohistochemistry - paraffin section; African green monkey; fig 2
Yasuda K, Cline C, Vogel P, Onciu M, Fatima S, Sorrentino B, et al. Drug transporters on arachnoid barrier cells contribute to the blood-cerebrospinal fluid barrier. Drug Metab Dispos. 2013;41:923-31 pubmed publisher
  • western blot; human; loading ...; fig 1d
Chen L, Yang G, Dong H. Everolimus Reverses Palbociclib Resistance in ER+ Human Breast Cancer Cells by Inhibiting Phosphatidylinositol 3-Kinase(PI3K)/Akt/Mammalian Target of Rapamycin (mTOR) Pathway. Med Sci Monit. 2019;25:77-86 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3a
Okada N, Murakami A, Urushizaki S, Matsuda M, Kawazoe K, Ishizawa K. Extracts of Immature Orange (Aurantii fructus immaturus) and Citrus Unshiu Peel (Citri unshiu pericarpium) Induce P-Glycoprotein and Cytochrome P450 3A4 Expression via Upregulation of Pregnane X Receptor. Front Pharmacol. 2017;8:84 pubmed publisher
  • western blot; human; 1:1000; fig 3
Li L, Liu H, Wang C, Liu X, Hu F, Xie N, et al. Overexpression of ?-Catenin Induces Cisplatin Resistance in Oral Squamous Cell Carcinoma. Biomed Res Int. 2016;2016:5378567 pubmed publisher
  • immunocytochemistry; rat; 1:5; fig 3e
Tome M, Herndon J, Schaefer C, Jacobs L, Zhang Y, Jarvis C, et al. P-glycoprotein traffics from the nucleus to the plasma membrane in rat brain endothelium during inflammatory pain. J Cereb Blood Flow Metab. 2016;36:1913-1928 pubmed
  • immunohistochemistry - paraffin section; human; 1:100; tbl 2
Sato K, Suda K, Shimizu S, Sakai K, Mizuuchi H, Tomizawa K, et al. Clinical, Pathological, and Molecular Features of Lung Adenocarcinomas with AXL Expression. PLoS ONE. 2016;11:e0154186 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 5
St George M, Ayoub A, Banerjee A, Churchill C, Winter P, Klobukowski M, et al. Designing and Testing of Novel Taxanes to Probe the Highly Complex Mechanisms by Which Taxanes Bind to Microtubules and Cause Cytotoxicity to Cancer Cells. PLoS ONE. 2015;10:e0129168 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:20; loading ...; fig 4B
Willyerd F, Empey P, Philbrick A, Ikonomovic M, Puccio A, Kochanek P, et al. Expression of ATP-Binding Cassette Transporters B1 and C1 after Severe Traumatic Brain Injury in Humans. J Neurotrauma. 2016;33:226-31 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:200
Alvariza S, Fagiolino P, Vázquez M, Feria Romero I, Orozco Suárez S. Chronic administration of phenytoin induces efflux transporter overexpression in rats. Pharmacol Rep. 2014;66:946-51 pubmed publisher
  • western blot; human
Li W, Zhong S, Wu Y, Xu W, Xu J, Tang J, et al. Systematic expression analysis of genes related to multidrug-resistance in isogenic docetaxel- and adriamycin-resistant breast cancer cell lines. Mol Biol Rep. 2013;40:6143-50 pubmed
  • immunohistochemistry - paraffin section; human; 1:40
  • western blot; human; 1:200; fig 4
Xie J, Li D, Chen X, Wang F, Dong P. Expression and significance of hypoxia-inducible factor-1? and MDR1/P-glycoprotein in laryngeal carcinoma tissue and hypoxic Hep-2 cells. Oncol Lett. 2013;6:232-238 pubmed
Huang H, Zhang X, Huang Z, Zhang Y, Zhou Z. Geniposide reverses multidrug resistance in vitro and in vivo by inhibiting the efflux function and expression of P-glycoprotein. Exp Ther Med. 2017;13:437-442 pubmed publisher
Yagdiran Y, Oskarsson A, Knight C, Tallkvist J. ABC- and SLC-Transporters in Murine and Bovine Mammary Epithelium--Effects of Prochloraz. PLoS ONE. 2016;11:e0151904 pubmed publisher
Huang J, Zhao M, Shi J, Zhang J, Li B, Fan W, et al. Expression of multidrug resistance 1 and multidrug resistance-related protein 1 in C57BL/6 mice treated with benzene. Genet Mol Res. 2013;12:5842-50 pubmed publisher
Wang N, Zhao L, Wu L, He M, Qu J, Zhao Y, et al. Mechanistic analysis of taxol-induced multidrug resistance in an ovarian cancer cell line. Asian Pac J Cancer Prev. 2013;14:4983-8 pubmed
Liu Y, Hsu H, Tseng K, Chen H, Chen S. Lgr5 promotes cancer stemness and confers chemoresistance through ABCB1 in colorectal cancer. Biomed Pharmacother. 2013;67:791-9 pubmed publisher
Watson P, Paterson J, Thom G, Ginman U, Lundquist S, Webster C. Modelling the endothelial blood-CNS barriers: a method for the production of robust in vitro models of the rat blood-brain barrier and blood-spinal cord barrier. BMC Neurosci. 2013;14:59 pubmed publisher
Gao J, Lv Q, Li L, Tang X, Li F, Hu Y, et al. Glioma targeting and blood-brain barrier penetration by dual-targeting doxorubincin liposomes. Biomaterials. 2013;34:5628-39 pubmed publisher
Benediktsdóttir B, Arason A, Halldorsson S, Gudjonsson T, Másson M, Baldursson O. Drug delivery characteristics of the progenitor bronchial epithelial cell line VA10. Pharm Res. 2013;30:781-91 pubmed publisher
Minami T, Kijima T, Otani Y, Kohmo S, Takahashi R, Nagatomo I, et al. HER2 as therapeutic target for overcoming ATP-binding cassette transporter-mediated chemoresistance in small cell lung cancer. Mol Cancer Ther. 2012;11:830-41 pubmed publisher
Zhang M, Garbuzenko O, Reuhl K, Rodriguez Rodriguez L, Minko T. Two-in-one: combined targeted chemo and gene therapy for tumor suppression and prevention of metastases. Nanomedicine (Lond). 2012;7:185-97 pubmed publisher
Kuo Y, Chen H. Effect of electromagnetic field on endocytosis of cationic solid lipid nanoparticles by human brain-microvascular endothelial cells. J Drug Target. 2010;18:447-56 pubmed publisher
Hoffmann K, Bekeredjian R, Schmidt J, Buchler M, Marten A. Effects of the high-affinity Peptide reversin 121 on multidrug resistance proteins in experimental pancreatic cancer. Tumour Biol. 2008;29:351-8 pubmed publisher
Hoffmann K, Mehrle S, Schmidt J, Buchler M, Marten A. Interferon-alpha restitutes the chemosensitivity in pancreatic cancer. Anticancer Res. 2008;28:1499-507 pubmed
Tribble N, Burka J, Kibenge F, Wright G. Identification and localization of a putative ATP-binding cassette transporter in sea lice (Lepeophtheirus salmonis) and host Atlantic salmon (Salmo salar). Parasitology. 2008;135:243-55 pubmed
Pakunlu R, Wang Y, Saad M, Khandare J, Starovoytov V, Minko T. In vitro and in vivo intracellular liposomal delivery of antisense oligonucleotides and anticancer drug. J Control Release. 2006;114:153-62 pubmed
product information
CatalogNumber :
ab3366
ItemName :
Anti-P Glycoprotein antibody [JSB-1]
Product Type :
Primary Antibodies
Host Species :
Mouse
Clonality :
Monoclonal
Conjugate :
Not Conjugated
Antigen Modification :
No Modifications
Clone Name :
JSB-1
Size :
250 µl
SpeciesSummary :
Hu, Ms, Rat
Uses :
ELISA, Flow Cyt, ICC/IF, IHC-P, IP
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK