| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; loading ...; fig 4d
| Lv W, Deng B, Duan W, Li Y, Liu Y, Li Z, et al. Schwann Cell Plasticity is Regulated by a Weakened Intrinsic Antioxidant Defense System in Acute Peripheral Nerve Injury. Neuroscience. 2018;382:1-13 pubmed publisher |
- immunohistochemistry; mouse; 1:100; loading ...; fig 4b
| Stancic A, Velickovic K, Markelic M, Grigorov I, Saksida T, Savić N, et al. Involvement of Ferroptosis in Diabetes-Induced Liver Pathology. Int J Mol Sci. 2022;23: pubmed publisher |
- western blot; mouse; 1:2000; loading ...; fig 2g
| Zhang C, Zhao M, Wang B, Su Z, Guo B, Qin L, et al. The Nrf2-NLRP3-caspase-1 axis mediates the neuroprotective effects of Celastrol in Parkinson's disease. Redox Biol. 2021;47:102134 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 4a
- western blot; mouse; 1:1000; loading ...; fig 5a
| Li Q, Xu Q, Tan J, Hu L, Ge C, Xu M. Carminic acid supplementation protects against fructose-induced kidney injury mainly through suppressing inflammation and oxidative stress via improving Nrf-2 signaling. Aging (Albany NY). 2021;13:10326-10353 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 2j
| Ryan B, Bengoa Vergniory N, Williamson M, Kirkiz E, Roberts R, Corda G, et al. REST protects dopaminergic neurons from mitochondrial and α-synuclein oligomer pathology in an alpha synuclein overexpressing BAC-transgenic mouse model. J Neurosci. 2021;: pubmed publisher |
- western blot; mouse; 1:200; loading ...; fig 4a
| Guo C, Sileikaite I, Davies M, Hawkins C. Myeloperoxidase Modulates Hydrogen Peroxide Mediated Cellular Damage in Murine Macrophages. Antioxidants (Basel). 2020;9: pubmed publisher |
- western blot; mouse; 1:2000; loading ...; fig 5b
| Pinterić M, Podgorski I, Hadžija M, Bujak I, Dekanic A, Bagarić R, et al. Role of Sirt3 in Differential Sex-Related Responses to a High-Fat Diet in Mice. Antioxidants (Basel). 2020;9: pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 5e
| Yu J, Wang W, Matei N, Li X, Pang J, Mo J, et al. Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats. Oxid Med Cell Longev. 2020;2020:4717258 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2d
| Tracey N, Creedon H, Kemp A, Culley J, Muir M, Klinowska T, et al. HO-1 drives autophagy as a mechanism of resistance against HER2-targeted therapies. Breast Cancer Res Treat. 2020;179:543-555 pubmed publisher |
- immunohistochemistry; mouse; fig 1e
- western blot; mouse; loading ...; fig 1f
| Choi W, Kim H, Kim M, Cinar R, Yi H, Eun H, et al. Glutamate Signaling in Hepatic Stellate Cells Drives Alcoholic Steatosis. Cell Metab. 2019;30:877-889.e7 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 3h
| Gong F, Gu J, Wang H. Up regulated Tmbim1 activation promotes high fat diet (HFD)-induced cardiomyopathy by enhancement of inflammation and oxidative stress. Biochem Biophys Res Commun. 2018;504:797-804 pubmed publisher |
- immunohistochemistry; mouse; 1:100; loading ...; fig 2a
- western blot; mouse; 1:1000; loading ...; fig 2d
| Ghosh A, Abdo S, Zhao S, Wu C, Shi Y, Lo C, et al. Insulin Inhibits Nrf2 Gene Expression via Heterogeneous Nuclear Ribonucleoprotein F/K in Diabetic Mice. Endocrinology. 2017;158:903-919 pubmed publisher |
- western blot; mouse; loading ...; fig 5a
| Ugun Klusek A, Tatham M, Elkharaz J, Constantin Teodosiu D, Lawler K, Mohamed H, et al. Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway. Cell Death Dis. 2017;8:e2531 pubmed publisher |
- immunocytochemistry; mouse; 1:150; loading ...; fig 3e
- western blot; mouse; 1:500; loading ...; fig 3b
| Zhou J, Ge L, Jia C, Zheng X, Cui H, Zong R, et al. ROS-mediated Different Homeostasis of Murine Corneal Epithelial Progenitor Cell Line under Oxidative Stress. Sci Rep. 2016;6:36481 pubmed publisher |
- western blot; mouse; 1:500; fig 4g
| Yang D, Yuan Q, Balakrishnan A, Bantel H, Klusmann J, Manns M, et al. MicroRNA-125b-5p mimic inhibits acute liver failure. Nat Commun. 2016;7:11916 pubmed publisher |
- immunocytochemistry; human; 1:100; fig 7
- immunohistochemistry - frozen section; guinea pig; 1:100; fig 4
| Han B, Poppinga W, Zuo H, Zuidhof A, Bos I, Smit M, et al. The novel compound Sul-121 inhibits airway inflammation and hyperresponsiveness in experimental models of chronic obstructive pulmonary disease. Sci Rep. 2016;6:26928 pubmed publisher |
- immunocytochemistry; rat; fig 7
- western blot; rat; 1:200; fig 6
| Shi X, Li Y, Hu J, Yu B. Tert-butylhydroquinone attenuates the ethanol-induced apoptosis of and activates the Nrf2 antioxidant defense pathway in H9c2 cardiomyocytes. Int J Mol Med. 2016;38:123-30 pubmed publisher |
- immunocytochemistry; mouse; 1:100; fig s2
| Moshfegh C, Aires L, Kisielow M, Vogel V. A gonogenic stimulated transition of mouse embryonic stem cells with enhanced control of diverse differentiation pathways. Sci Rep. 2016;6:25104 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 4a
- western blot; human; loading ...; fig 4e
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| Chao C, Huang C, Cheng J, Chiou C, Lee I, Yang Y, et al. SRT1720 as an SIRT1 activator for alleviating paraquat-induced models of Parkinson's disease. Redox Biol. 2022;58:102534 pubmed publisher |
| Cai W, Srivastava P, Feng D, Lin Y, Vanderburg C, Xu Y, et al. Melanocortin 1 receptor activation protects against alpha-synuclein pathologies in models of Parkinson's disease. Mol Neurodegener. 2022;17:16 pubmed publisher |
| D Ezio V, Colasanti M, Persichini T. Amyloid-β 25-35 Induces Neurotoxicity through the Up-Regulation of Astrocytic System Xc. Antioxidants (Basel). 2021;10: pubmed publisher |
| Jiang B, Li Y, Dai W, Wu A, Wu H, Mao D. Hydrogen-rich saline alleviates early brain injury through regulating of ER stress and autophagy after experimental subarachnoid hemorrhage. Acta Cir Bras. 2021;36:e360804 pubmed publisher |
| Aleksic M, Kalezic A, Saso L, Jankovic A, Korac B, Korac A. The Unity of Redox and Structural Remodeling of Brown Adipose Tissue in Hypothyroidism. Antioxidants (Basel). 2021;10: pubmed publisher |
| Zhang W, Yu H, Lin Q, Liu X, Cheng Y, Deng B. Anti-inflammatory effect of resveratrol attenuates the severity of diabetic neuropathy by activating the Nrf2 pathway. Aging (Albany NY). 2021;13:10659-10671 pubmed publisher |
| Ke B, Zhang T, An T, Lu R. Soy isoflavones ameliorate the cognitive dysfunction of Goto-Kakizaki rats by activating the Nrf2-HO-1 signalling pathway. Aging (Albany NY). 2020;12:21344-21354 pubmed publisher |
| Wang G, Zhang X, Lu X, Liu J, Zhang Z, Wei Z, et al. Fish oil supplementation attenuates cognitive impairment by inhibiting neuroinflammation in STZ-induced diabetic rats. Aging (Albany NY). 2020;12:15281-15289 pubmed publisher |
| B Gowda S, Fuda H, Tsukui T, Chiba H, Hui S. Discovery of Eicosapentaenoic Acid Esters of Hydroxy Fatty Acids as Potent Nrf2 Activators. Antioxidants (Basel). 2020;9: pubmed publisher |
| Wheeler M, Clark I, Tjon E, Li Z, Zandee S, Couturier C, et al. MAFG-driven astrocytes promote CNS inflammation. Nature. 2020;578:593-599 pubmed publisher |
| Gao K, Liu M, Ding Y, Yao M, Zhu Y, Zhao J, et al. A phenolic amide (LyA) isolated from the fruits of Lycium barbarum protects against cerebral ischemia-reperfusion injury via PKCε/Nrf2/HO-1 pathway. Aging (Albany NY). 2019;11:12361-12374 pubmed publisher |
| Li J, Hu X, Liang F, Liu J, Zhou H, Liu J, et al. Therapeutic effects of moxibustion simultaneously targeting Nrf2 and NF-κB in diabetic peripheral neuropathy. Appl Biochem Biotechnol. 2019;: pubmed publisher |
| Luz N, DeSouza Vieira T, de Castro W, Vivarini A, Pereira L, França R, et al. Lutzomyia longipalpis Saliva Induces Heme Oxygenase-1 Expression at Bite Sites. Front Immunol. 2018;9:2779 pubmed publisher |
| Matsui S, Sasaki T, Kohno D, Yaku K, Inutsuka A, Yokota Hashimoto H, et al. Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice. Nat Commun. 2018;9:4604 pubmed publisher |
| Liu X, Lin X, Zhang S, Guo C, Li J, Mi Y, et al. Lycopene ameliorates oxidative stress in the aging chicken ovary via activation of Nrf2/HO-1 pathway. Aging (Albany NY). 2018;10:2016-2036 pubmed publisher |
| Li C, Cheng L, Wu H, He P, Zhang Y, Yang Y, et al. Activation of the KEAP1‑NRF2‑ARE signaling pathway reduces oxidative stress in Hep2 cells. Mol Med Rep. 2018;18:2541-2550 pubmed publisher |
| Vincent A, Rosa H, Pabis K, Lawless C, Chen C, Grünewald A, et al. Subcellular origin of mitochondrial DNA deletions in human skeletal muscle. Ann Neurol. 2018;84:289-301 pubmed publisher |
| Zhang G, Kang Y, Zhou C, Cui R, Jia M, Hu S, et al. Amelioratory Effects of Testosterone Propionate on Age-related Renal Fibrosis via Suppression of TGF-?1/Smad Signaling and Activation of Nrf2-ARE Signaling. Sci Rep. 2018;8:10726 pubmed publisher |
| Zhao J, Ren S, Liu C, Huo L, Liu Z, Zhai L. Di-(2-Ethylhexyl) Phthalate Increases Obesity-Induced Damage to the Male Reproductive System in Mice. Oxid Med Cell Longev. 2018;2018:1861984 pubmed publisher |
| Zhu B, Tang L, Chen S, Yin C, Peng S, Li X, et al. Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy. Oncogene. 2018;37:4941-4954 pubmed publisher |
| Zhang X, Ma Z, Yuan Y, Xu S, Wei W, Song P, et al. Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling. Cell Death Dis. 2018;9:102 pubmed publisher |
| Zhang Z, Qu J, Zheng C, Zhang P, Zhou W, Cui W, et al. Nrf2 antioxidant pathway suppresses Numb-mediated epithelial-mesenchymal transition during pulmonary fibrosis. Cell Death Dis. 2018;9:83 pubmed publisher |
| Abebe T, Mahadevan J, Bogachus L, Hahn S, Black M, Oseid E, et al. Nrf2/antioxidant pathway mediates β cell self-repair after damage by high-fat diet-induced oxidative stress. JCI Insight. 2017;2: pubmed publisher |
| Sun W, Meng J, Wang Z, Yuan T, Qian H, Chen W, et al. Proanthocyanidins Attenuation of H2O2-Induced Oxidative Damage in Tendon-Derived Stem Cells via Upregulating Nrf-2 Signaling Pathway. Biomed Res Int. 2017;2017:7529104 pubmed publisher |
| Akbari G, Mard S, Dianat M, Mansouri E. The Hepatoprotective and MicroRNAs Downregulatory Effects of Crocin Following Hepatic Ischemia-Reperfusion Injury in Rats. Oxid Med Cell Longev. 2017;2017:1702967 pubmed publisher |
| Yang X, Park S, Chang H, Shapiro J, Vassilopoulos A, Sawicki K, et al. Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2. J Clin Invest. 2017;127:1505-1516 pubmed publisher |
| Klein S, Cambier S, Hennen J, Legay S, Serchi T, Nelissen I, et al. Endothelial responses of the alveolar barrier in vitro in a dose-controlled exposure to diesel exhaust particulate matter. Part Fibre Toxicol. 2017;14:7 pubmed publisher |
| Jin F, Wan C, Li W, Yao L, Zhao H, Zou Y, et al. Formononetin protects against acetaminophen-induced hepatotoxicity through enhanced NRF2 activity. PLoS ONE. 2017;12:e0170900 pubmed publisher |
| Wang Z, Sun D, Chen G, Li G, Dou S, Wang R, et al. Tim-3 inhibits macrophage control of Listeria monocytogenes by inhibiting Nrf2. Sci Rep. 2017;7:42095 pubmed publisher |
| Chaiprasongsuk A, Lohakul J, Soontrapa K, Sampattavanich S, Akarasereenont P, Panich U. Activation of Nrf2 Reduces UVA-Mediated MMP-1 Upregulation via MAPK/AP-1 Signaling Cascades: The Photoprotective Effects of Sulforaphane and Hispidulin. J Pharmacol Exp Ther. 2017;360:388-398 pubmed publisher |
| Li C, Wu H, Wang S, Zhu J. Expression and correlation of NRF2, KEAP1, NQO-1 and HO-1 in advanced squamous cell carcinoma of the larynx and their association with clinicopathologic features. Mol Med Rep. 2016;14:5171-5179 pubmed publisher |
| Feng C, Hung H, Huang S, Chen C, Chen Y, Chen C, et al. Neuroprotective Effect of the Marine-Derived Compound 11-Dehydrosinulariolide through DJ-1-Related Pathway in In Vitro and In Vivo Models of Parkinson's Disease. Mar Drugs. 2016;14: pubmed |
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| Chen M, Wang M, Yang Q, Wang M, Wang Z, Zhu Y, et al. Antioxidant effects of hydroxysafflor yellow A and acetyl-11-keto-?-boswellic acid in combination on isoproterenol-induced myocardial injury in rats. Int J Mol Med. 2016;37:1501-10 pubmed publisher |
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| Cheng J, Li J, Huang M, Ma L, Wu Z, Jiang C, et al. CD36 is a co-receptor for hepatitis C virus E1 protein attachment. Sci Rep. 2016;6:21808 pubmed publisher |
