This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-TGF beta Receptor I antibody
catalog :
ab31013
quantity :
1 ml, 500 µl
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other
citations: 30
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig s4g
Wu T, Wang W, Shi G, Hao M, Wang Y, Yao M, et al. Targeting HIC1/TGF-β axis-shaped prostate cancer microenvironment restrains its progression. Cell Death Dis. 2022;13:624 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 6c
Srivastava S, Zhou H, Setia O, Dardik A, Fernandez Hernando C, GOODWIN J. Podocyte Glucocorticoid Receptors Are Essential for Glomerular Endothelial Cell Homeostasis in Diabetes Mellitus. J Am Heart Assoc. 2021;10:e019437 pubmed publisher
  • western blot; human; fig 7b
  • immunohistochemistry; mouse; loading ...; fig 4c
Srivastava S, Zhou H, Setia O, Liu B, Kanasaki K, Koya D, et al. Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy. Nat Commun. 2021;12:2368 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1c
  • immunohistochemistry; mouse; loading ...; fig 1l
  • western blot; mouse; loading ...; fig 1k
Nishad R, Mukhi D, Singh A, Motrapu M, Chintala K, Tammineni P, et al. Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria. Cell Death Dis. 2021;12:342 pubmed publisher
  • western blot; mouse; 1:1000; fig 11c
Chen Y, Jhao P, Hung C, Wu Y, Lin S, Chiang W, et al. Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGF-β signaling in kidney fibroblasts. J Clin Invest. 2021;131: pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 6d
Lee T, Yeh C, Lee Y, Shih Y, Chen Y, Hung C, et al. Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization. Nat Commun. 2020;11:4254 pubmed publisher
  • other; mouse; 1:100; loading ...; fig 2c
Voisin A, Damon Soubeyrand C, Bravard S, Saez F, Drevet J, Guiton R. Differential expression and localisation of TGF-β isoforms and receptors in the murine epididymis. Sci Rep. 2020;10:995 pubmed publisher
  • western blot; human; 1:750; loading ...; fig 5e
Minuesa G, Albanese S, Xie W, Kazansky Y, Worroll D, Chow A, et al. Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia. Nat Commun. 2019;10:2691 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200
Rickelt S, Hynes R. Antibodies and methods for immunohistochemistry of extracellular matrix proteins. Matrix Biol. 2018;71-72:10-27 pubmed publisher
  • immunoprecipitation; rat; loading ...; fig 6a
  • western blot; rat; 1:750; loading ...; fig 6a
Zhang R, Wu Y, Xie F, Zhong Y, Wang Y, Xu M, et al. RGMa mediates reactive astrogliosis and glial scar formation through TGF?1/Smad2/3 signaling after stroke. Cell Death Differ. 2018;25:1503-1516 pubmed publisher
  • western blot; mouse; fig 6d
Wang Q, Yu Y, Zhang P, Chen Y, Li C, Chen J, et al. The crucial role of activin A/ALK4 pathway in the pathogenesis of Ang-II-induced atrial fibrosis and vulnerability to atrial fibrillation. Basic Res Cardiol. 2017;112:47 pubmed publisher
  • western blot; mouse; fig 6c
Koyama Y, Wang P, Liang S, Iwaisako K, Liu X, Xu J, et al. Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis. J Clin Invest. 2017;127:1254-1270 pubmed publisher
Huang S, Mo C, Zeng T, Lai Y, Zhou C, Xie S, et al. Lupeol ameliorates LPS/D-GalN induced acute hepatic damage by suppressing inflammation and oxidative stress through TGFβ1-Nrf2 signal pathway. Aging (Albany NY). 2021;13:6592-6605 pubmed publisher
Sharma A, Kilari S, Cai C, Simeon M, Misra S. Increased fibrotic signaling in a murine model for intra-arterial contrast-induced acute kidney injury. Am J Physiol Renal Physiol. 2020;318:F1210-F1219 pubmed publisher
Li S, Tu C, Wan L, Chen R, Duan Z, Ren X, et al. FGF-induced LHX9 regulates the progression and metastasis of osteosarcoma via FRS2/TGF-β/β-catenin pathway. Cell Div. 2019;14:13 pubmed publisher
Chae D, Park J, Cho M, Ban E, Jang M, Yoo Y, et al. MiR-195 and miR-497 suppress tumorigenesis in lung cancer by inhibiting SMURF2-induced TGF-β receptor I ubiquitination. Mol Oncol. 2019;13:2663-2678 pubmed publisher
Gu Y, Wang W, Wang X, Xie H, Ye X, Shu P. Integrated network analysis identifies hsa-miR-4756-3p as a regulator of FOXM1 in Triple Negative Breast Cancer. Sci Rep. 2019;9:13830 pubmed publisher
Gurrapu S, Franzolin G, Fard D, Accardo M, Medico E, Sarotto I, et al. Reverse signaling by semaphorin 4C elicits SMAD1/5- and ID1/3-dependent invasive reprogramming in cancer cells. Sci Signal. 2019;12: pubmed publisher
Yang J, Zhang Y, Xu X, Li J, Yuan F, Bo S, et al. Transforming growth factor-β is involved in maintaining oocyte meiotic arrest by promoting natriuretic peptide type C expression in mouse granulosa cells. Cell Death Dis. 2019;10:558 pubmed publisher
Jiang Y, Sun A, Zhao Y, Ying W, Sun H, Yang X, et al. Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma. Nature. 2019;567:257-261 pubmed publisher
Xu Q, Jia H, Ma L, Liu G, Xu C, Li Y, et al. All-trans retinoic acid inhibits lipopolysaccharide-induced inflammatory responses in bovine adipocytes via TGFβ1/Smad3 signaling pathway. BMC Vet Res. 2019;15:48 pubmed publisher
Zhang X, Xu Y, Qian Z, Zheng W, Wu Q, Chen Y, et al. circRNA_104075 stimulates YAP-dependent tumorigenesis through the regulation of HNF4a and may serve as a diagnostic marker in hepatocellular carcinoma. Cell Death Dis. 2018;9:1091 pubmed publisher
Hou L, Tu J, Cheng F, Yang H, Yu F, Wang M, et al. Long noncoding RNA ROR promotes breast cancer by regulating the TGF-β pathway. Cancer Cell Int. 2018;18:142 pubmed publisher
Yang T, Zhang X, Ma C, Chen Y. TGF-β/Smad3 pathway enhances the cardio-protection of S1R/SIPR1 in in vitro ischemia-reperfusion myocardial cell model. Exp Ther Med. 2018;16:178-184 pubmed publisher
Niwa T, Yamakoshi Y, Yamazaki H, Karakida T, Chiba R, Hu J, et al. The dynamics of TGF-β in dental pulp, odontoblasts and dentin. Sci Rep. 2018;8:4450 pubmed publisher
Li H, Chen C. Inhibition of autophagy enhances synergistic effects of Salidroside and anti-tumor agents against colorectal cancer. BMC Complement Altern Med. 2017;17:538 pubmed publisher
Gencer S, Oleinik N, Kim J, Panneer Selvam S, De Palma R, Dany M, et al. TGF-β receptor I/II trafficking and signaling at primary cilia are inhibited by ceramide to attenuate cell migration and tumor metastasis. Sci Signal. 2017;10: pubmed publisher
Bian S, Zheng X, Sun H, Chen J, Lu Y, Liu Y, et al. Clock1a affects mesoderm development and primitive hematopoiesis by regulating Nodal-Smad3 signaling in the zebrafish embryo. J Biol Chem. 2017;292:14165-14175 pubmed publisher
Li S, Wang L, Liu M, Jiang S, Zhang M, Tian Z, et al. Cannabinoid CBâ‚‚ receptors are involved in the regulation of fibrogenesis during skin wound repair in mice. Mol Med Rep. 2016;13:3441-50 pubmed publisher
Goodier H, Carr A, Snelling S, Roche L, Wheway K, Watkins B, et al. Comparison of transforming growth factor beta expression in healthy and diseased human tendon. Arthritis Res Ther. 2016;18:48 pubmed publisher
product information
CatalogNumber :
ab31013
ItemName :
Anti-TGF beta Receptor I antibody
Category :
Antibody
Host :
Rabbit
Clonality :
Polyclonal
Conjugate :
Unconjugated
Size :
1 ml, 500 µl
SpeciesSummary :
Cow, Hu, Ms, Rat
Application Summary :
Flow Cyt, ICC/IF, IHC-Fr, IHC-P, IP, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK