This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-Calcium channel L type DHPR alpha 2 subunit antibody [20A]
catalog :
ab2864
quantity :
100 µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
20A
reactivity :
human, mouse, rat, chicken, domestic rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 31
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; loading ...; fig 1a
Hu J, Gao C, Wei C, Xue Y, Shao C, Hao Y, et al. RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure. Proc Natl Acad Sci U S A. 2019;116:6172-6180 pubmed publisher
  • western blot; mouse; loading ...; fig 5a
Eshima H, Tamura Y, Kakehi S, Kurebayashi N, Murayama T, Nakamura K, et al. Long-term, but not short-term high-fat diet induces fiber composition changes and impaired contractile force in mouse fast-twitch skeletal muscle. Physiol Rep. 2017;5: pubmed publisher
  • western blot; rat; loading ...; fig 2e
Himori K, Abe M, Tatebayashi D, Lee J, Westerblad H, Lanner J, et al. Superoxide dismutase/catalase mimetic EUK-134 prevents diaphragm muscle weakness in monocrotalin-induced pulmonary hypertension. PLoS ONE. 2017;12:e0169146 pubmed publisher
  • western blot; mouse; 1:1000; fig 5a
Huang M, Lee K, Kim K, Ahn M, Cho C, Kim D, et al. The maintenance ability and Ca2+ availability of skeletal muscle are enhanced by sildenafil. Exp Mol Med. 2016;48:e278 pubmed publisher
  • western blot; mouse; loading ...; fig 4
Ivarsson N, Schiffer T, Hernandez A, Lanner J, Weitzberg E, Lundberg J, et al. Dietary nitrate markedly improves voluntary running in mice. Physiol Behav. 2017;168:55-61 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500; fig 1b
Yu D, Holm R, Goscinski M, Trope C, Nesland J, Suo Z. Prognostic and clinicopathological significance of Cacna2d1 expression in epithelial ovarian cancers: a retrospective study. Am J Cancer Res. 2016;6:2088-2097 pubmed
  • immunohistochemistry; mouse; 1:400; fig 3
Vilmont V, Cadot B, Vezin E, Le Grand F, Gomes E. Dynein disruption perturbs post-synaptic components and contributes to impaired MuSK clustering at the NMJ: implication in ALS. Sci Rep. 2016;6:27804 pubmed publisher
  • immunohistochemistry; mouse; 1:400; fig 4
Vilmont V, Cadot B, Ouanounou G, Gomes E. A system for studying mechanisms of neuromuscular junction development and maintenance. Development. 2016;143:2464-77 pubmed publisher
  • western blot; human; fig 2
  • western blot; mouse; fig 1
Toral Ojeda I, Aldanondo G, Lasa Elgarresta J, Lasa Fernández H, Fernandez Torron R, Lopez de Munain A, et al. Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle. Expert Rev Mol Med. 2016;18:e7 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:50; fig 5
Bragança B, Oliveira Monteiro N, Ferreirinha F, Lima P, Faria M, Fontes Sousa A, et al. Ion Fluxes through KCa2 (SK) and Cav1 (L-type) Channels Contribute to Chronoselectivity of Adenosine A1 Receptor-Mediated Actions in Spontaneously Beating Rat Atria. Front Pharmacol. 2016;7:45 pubmed publisher
  • western blot; human
Gineste C, Hernandez A, Ivarsson N, Cheng A, Naess K, Wibom R, et al. Cyclophilin D, a target for counteracting skeletal muscle dysfunction in mitochondrial myopathy. Hum Mol Genet. 2015;24:6580-7 pubmed publisher
  • western blot; human; fig 3e
Hostrup M, Kalsen A, Onslev J, Jessen S, Haase C, Habib S, et al. Mechanisms underlying enhancements in muscle force and power output during maximal cycle ergometer exercise induced by chronic β2-adrenergic stimulation in men. J Appl Physiol (1985). 2015;119:475-86 pubmed publisher
  • western blot; domestic rabbit; loading ...; fig 1a
Hu H, Wang Z, Wei R, Fan G, Wang Q, Zhang K, et al. The molecular architecture of dihydropyrindine receptor/L-type Ca2+ channel complex. Sci Rep. 2015;5:8370 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2a
Rougier J, Albesa M, Syam N, Halet G, Abriel H, Viard P. Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α2δ-1-induced downregulation of Cav1.2 channels. Pflugers Arch. 2015;467:1919-29 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Katuri V, Gerber S, Qiu X, McCarty G, Goldstein S, Hammers H, et al. WT1 regulates angiogenesis in Ewing Sarcoma. Oncotarget. 2014;5:2436-49 pubmed
Ivarsson N, Mattsson C, Cheng A, Bruton J, Ekblom B, Lanner J, et al. SR Ca2+ leak in skeletal muscle fibers acts as an intracellular signal to increase fatigue resistance. J Gen Physiol. 2019;151:567-577 pubmed publisher
Yamada T, Abe M, Lee J, Tatebayashi D, Himori K, Kanzaki K, et al. Muscle dysfunction associated with adjuvant-induced arthritis is prevented by antioxidant treatment. Skelet Muscle. 2015;5:20 pubmed publisher
Yamada T, Ivarsson N, Hernandez A, Fahlström A, Cheng A, Zhang S, et al. Impaired mitochondrial respiration and decreased fatigue resistance followed by severe muscle weakness in skeletal muscle of mitochondrial DNA mutator mice. J Physiol. 2012;590:6187-97 pubmed publisher
Gonon A, Jung C, Katz A, Westerblad H, Shemyakin A, Sjöquist P, et al. Local arginase inhibition during early reperfusion mediates cardioprotection via increased nitric oxide production. PLoS ONE. 2012;7:e42038 pubmed publisher
Wilson O, Shaw C, Sherlock M, Stewart P, Wagenmakers A. Immunofluorescent visualisation of focal adhesion kinase in human skeletal muscle and its associated microvasculature. Histochem Cell Biol. 2012;138:617-26 pubmed publisher
Lampson B, Kendall S, Ancrile B, Morrison M, Shealy M, Barrientos K, et al. Targeting eNOS in pancreatic cancer. Cancer Res. 2012;72:4472-82 pubmed publisher
Hernandez A, Schiffer T, Ivarsson N, Cheng A, Bruton J, Lundberg J, et al. Dietary nitrate increases tetanic [Ca2+]i and contractile force in mouse fast-twitch muscle. J Physiol. 2012;590:3575-83 pubmed publisher
Templin C, Ghadri J, Rougier J, Baumer A, Kaplan V, Albesa M, et al. Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6). Eur Heart J. 2011;32:1077-88 pubmed publisher
Rougier J, Albesa M, Abriel H, Viard P. Neuronal precursor cell-expressed developmentally down-regulated 4-1 (NEDD4-1) controls the sorting of newly synthesized Ca(V)1.2 calcium channels. J Biol Chem. 2011;286:8829-38 pubmed publisher
Danalache B, Gutkowska J, Slusarz M, Berezowska I, Jankowski M. Oxytocin-Gly-Lys-Arg: a novel cardiomyogenic peptide. PLoS ONE. 2010;5:e13643 pubmed publisher
Bruton J, Aydin J, Yamada T, Shabalina I, Ivarsson N, Zhang S, et al. Increased fatigue resistance linked to Ca2+-stimulated mitochondrial biogenesis in muscle fibres of cold-acclimated mice. J Physiol. 2010;588:4275-88 pubmed publisher
Yamada T, Zhang S, Westerblad H, Katz A. {beta}-Hydroxybutyrate inhibits insulin-mediated glucose transport in mouse oxidative muscle. Am J Physiol Endocrinol Metab. 2010;299:E364-73 pubmed publisher
Yamada T, Place N, Kosterina N, Ostberg T, Zhang S, Grundtman C, et al. Impaired myofibrillar function in the soleus muscle of mice with collagen-induced arthritis. Arthritis Rheum. 2009;60:3280-9 pubmed publisher
Walsh C, Davies A, Butcher A, Dolphin A, Kitmitto A. Three-dimensional structure of CaV3.1: comparison with the cardiac L-type voltage-gated calcium channel monomer architecture. J Biol Chem. 2009;284:22310-21 pubmed publisher
Salomonsson S, Grundtman C, Zhang S, Lanner J, Li C, Katz A, et al. Upregulation of MHC class I in transgenic mice results in reduced force-generating capacity in slow-twitch muscle. Muscle Nerve. 2009;39:674-82 pubmed publisher
Aydin J, Andersson D, Hänninen S, Wredenberg A, Tavi P, Park C, et al. Increased mitochondrial Ca2+ and decreased sarcoplasmic reticulum Ca2+ in mitochondrial myopathy. Hum Mol Genet. 2009;18:278-88 pubmed publisher
product information
CatalogNumber :
ab2864
ItemName :
Anti-Calcium channel L type DHPR alpha 2 subunit antibody [20A]
Category :
Antibody
Host :
Mouse
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
20A
Size :
100 µl
SpeciesSummary :
Chk, Gpig, Hu, Ms, Pig, Rat, Rb
Application Summary :
Flow Cyt, ICC, ICC/IF, IHC-Fr, IHC-P, IP, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK