This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
TGF beta 1 antibody [TB21]
catalog :
ab27969
quantity :
50 ug
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
TB21
reactivity :
human, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, blocking or activating experiments
citations: 25
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000; loading ...; fig 2a
Wei T, Richter G, Zhang H, Sun R, Smith C, STRUB G. Extracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1. Sci Rep. 2022;12:16612 pubmed publisher
  • blocking or activating experiments; human; fig 6
Zhao C, Zhang W, Zhao Y, Yang Y, Luo H, Ji G, et al. Endothelial Cords Promote Tumor Initial Growth prior to Vascular Function through a Paracrine Mechanism. Sci Rep. 2016;6:19404 pubmed publisher
  • western blot; rat; 1:500; loading ...; fig 2c
Li X, Wu Y, Li X, Li D, Du J, Hu C, et al. Role of eukaryotic translation initiation factor 3a in bleomycin-induced pulmonary fibrosis. Eur J Pharmacol. 2015;749:89-97 pubmed publisher
  • immunohistochemistry; rat
Yan J, Chen Y, Yuan Q, Wang X, Yu S, Qiu W, et al. Comparison of the effects of Mg-6Zn and Ti-3Al-2.5V alloys on TGF-?/TNF-?/VEGF/b-FGF in the healing of the intestinal tract in vivo. Biomed Mater. 2014;9:025011 pubmed publisher
  • western blot; rat; 1:2000
Gay Jordi G, Guash E, Benito B, Brugada J, Nattel S, Mont L, et al. Losartan prevents heart fibrosis induced by long-term intensive exercise in an animal model. PLoS ONE. 2013;8:e55427 pubmed publisher
Peng C, Zou X, Xia W, Gao H, Li Z, Liu N, et al. Integrin αvβ6 plays a bi-directional regulation role between colon cancer cells and cancer-associated fibroblasts. Biosci Rep. 2018;38: pubmed publisher
Song W, He D, Chen Y, Yeh C, Hsu I, Huang Q, et al. Targeting newly identified ERβ/TGF-β1/SMAD3 signals with the FDA-approved anti-estrogen Faslodex or an ERβ selective antagonist in renal cell carcinoma. Mol Oncol. 2018;12:2055-2071 pubmed publisher
Cao H, Zhou Q, Lan R, Røe O, Chen X, Chen Y, et al. A functional polymorphism C-509T in TGFβ-1 promoter contributes to susceptibility and prognosis of lone atrial fibrillation in Chinese population. PLoS ONE. 2014;9:e112912 pubmed publisher
Li F, Dong L, Xing R, Wang L, Luan F, Yao C, et al. Homeobox B9 is overexpressed in hepatocellular carcinomas and promotes tumor cell proliferation both in vitro and in vivo. Biochem Biophys Res Commun. 2014;444:241-7 pubmed publisher
Botfield H, Gonzalez A, Abdullah O, Skjolding A, Berry M, McAllister J, et al. Decorin prevents the development of juvenile communicating hydrocephalus. Brain. 2013;136:2842-58 pubmed publisher
Yan J, Chen Y, Yuan Q, Yu S, Qiu W, Yang C, et al. Comparison of the effects of Mg-6Zn and titanium on intestinal tract in vivo. J Mater Sci Mater Med. 2013;24:1515-25 pubmed publisher
Zhu Y, Colak T, Shenoy M, Liu L, Mehta K, Pai R, et al. Transforming growth factor beta induces sensory neuronal hyperexcitability, and contributes to pancreatic pain and hyperalgesia in rats with chronic pancreatitis. Mol Pain. 2012;8:65 pubmed publisher
Soltani A, Sohal S, Reid D, Weston S, Wood Baker R, Walters E. Vessel-associated transforming growth factor-beta1 (TGF-?1) is increased in the bronchial reticular basement membrane in COPD and normal smokers. PLoS ONE. 2012;7:e39736 pubmed publisher
DU J, Sun M, DU G, Li F, Liu C, Mu Y, et al. Ingredients of Huangqi decoction slow biliary fibrosis progression by inhibiting the activation of the transforming growth factor-beta signaling pathway. BMC Complement Altern Med. 2012;12:33 pubmed publisher
Grzibovskis M, Urtane I, Pilmane M. Specific signaling molecule expression in periodontal ligaments in different age groups: pilot study. Stomatologija. 2011;13:117-22 pubmed
Mu E, Ding R, An X, Li X, Chen S, Ma X. Heparin attenuates lipopolysaccharide-induced acute lung injury by inhibiting nitric oxide synthase and TGF-?/Smad signaling pathway. Thromb Res. 2012;129:479-85 pubmed publisher
Ishikawa K, Ladage D, Takewa Y, Yaniz E, Chen J, Tilemann L, et al. Development of a preclinical model of ischemic cardiomyopathy in swine. Am J Physiol Heart Circ Physiol. 2011;301:H530-7 pubmed publisher
Minoo P, Zlobec I, Peterson M, Terracciano L, Lugli A. Characterization of rectal, proximal and distal colon cancers based on clinicopathological, molecular and protein profiles. Int J Oncol. 2010;37:707-18 pubmed
Wang L, Wen W, Yuan J, Helfand B, Li Y, Shi C, et al. Immunotherapy for human renal cell carcinoma by adoptive transfer of autologous transforming growth factor beta-insensitive CD8+ T cells. Clin Cancer Res. 2010;16:164-73 pubmed publisher
Ares Carrasco S, Picatoste B, Benito Martin A, Zubiri I, Sanz A, Sanchez Niño M, et al. Myocardial fibrosis and apoptosis, but not inflammation, are present in long-term experimental diabetes. Am J Physiol Heart Circ Physiol. 2009;297:H2109-19 pubmed publisher
Justulin L, Acquaro C, Carvalho R, Silva M, Felisbino S. Combined effect of the finasteride and doxazosin on rat ventral prostate morphology and physiology. Int J Androl. 2010;33:489-99 pubmed publisher
Song S, Kwak I, Yang B, Lee D, Lee S, Lee M. Role of rosiglitazone in lipopolysaccharide-induced peritonitis: a rat peritoneal dialysis model. Nephrology (Carlton). 2009;14:155-63 pubmed publisher
Mantoni T, Schendel R, Rodel F, Niedobitek G, Al Assar O, Masamune A, et al. Stromal SPARC expression and patient survival after chemoradiation for non-resectable pancreatic adenocarcinoma. Cancer Biol Ther. 2008;7:1806-15 pubmed
Narkiewicz J, Klasa Mazurkiewicz D, Zurawa Janicka D, Skorko Glonek J, Emerich J, Lipinska B. Changes in mRNA and protein levels of human HtrA1, HtrA2 and HtrA3 in ovarian cancer. Clin Biochem. 2008;41:561-9 pubmed publisher
Zlobec I, Baker K, Minoo P, Jass J, Terracciano L, Lugli A. Node-negative colorectal cancer at high risk of distant metastasis identified by combined analysis of lymph node status, vascular invasion, and Raf-1 kinase inhibitor protein expression. Clin Cancer Res. 2008;14:143-8 pubmed publisher
product information
Catalog Number :
ab27969
Product Name :
TGF beta 1 antibody [TB21]
Host Species :
Mouse
Clonality :
monoclonal
Product Type :
Primary antibodies
Size :
50 ug
SwissProtID :
P01137
Isotype :
IgG1
CrossReactivity :
Reacts with: Human, Rat, Pig, Sheep.
Application Summary :
ELISA, ICC/IF, IHC-Fr, IHC-P, Neut, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK