This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-CFTR antibody [CF3]
catalog :
ab2784
quantity :
100 µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CF3
reactivity :
human, mouse, rat, chicken, pigs
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, western blot knockout validation
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:1000; fig 2
Tosco A, De Gregorio F, Esposito S, De Stefano D, Sana I, Ferrari E, et al. A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR. Cell Death Differ. 2016;23:1380-93 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 1b
Zhang S, Shrestha C, Kopp B. Cystic fibrosis transmembrane conductance regulator (CFTR) modulators have differential effects on cystic fibrosis macrophage function. Sci Rep. 2018;8:17066 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5b
  • immunocytochemistry; human; fig 2i
Romani L, Oikonomou V, Moretti S, Iannitti R, D Adamo M, Villella V, et al. Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis. Nat Med. 2017;23:590-600 pubmed publisher
  • western blot; human; 1:500; fig 1b
  • western blot; mouse; 1:500; fig 3b
Jin H, Wen G, Deng S, Wan S, Xu J, Liu X, et al. Oestrogen upregulates the expression levels and functional activities of duodenal mucosal CFTR and SLC26A6. Exp Physiol. 2016;101:1371-1382 pubmed publisher
  • western blot; human; fig s2
Khoory J, Estanislau J, Elkhal A, Lazaar A, Melhorn M, Brodsky A, et al. Ligation of Glycophorin A Generates Reactive Oxygen Species Leading to Decreased Red Blood Cell Function. PLoS ONE. 2016;11:e0141206 pubmed publisher
  • flow cytometry; human; 1:20; fig 1b
Fanelli M, Hattinger C, Vella S, Tavanti E, Michelacci F, Gudeman B, et al. Targeting ABCB1 and ABCC1 with their Specific Inhibitor CBT-1® can Overcome Drug Resistance in Osteosarcoma. Curr Cancer Drug Targets. 2016;16:261-74 pubmed
  • immunohistochemistry; human; fig 3
Li H, Chen L, Zeng S, Li X, Zhang X, Lin C, et al. Matrigel basement membrane matrix induces eccrine sweat gland cells to reconstitute sweat gland-like structures in nude mice. Exp Cell Res. 2015;332:67-77 pubmed publisher
  • immunohistochemistry; pigs ; 1:50
McLatchie L, Young J, Fry C. Regulation of ACh release from guinea pig bladder urothelial cells: potential role in bladder filling sensations. Br J Pharmacol. 2014;171:3394-403 pubmed publisher
Abbattiscianni A, Favia M, Mancini M, Cardone R, Guerra L, Monterisi S, et al. Correctors of mutant CFTR enhance subcortical cAMP-PKA signaling through modulating ezrin phosphorylation and cytoskeleton organization. J Cell Sci. 2016;129:1128-40 pubmed publisher
De Stefano D, Villella V, Esposito S, Tosco A, Sepe A, de Gregorio F, et al. Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation. Autophagy. 2014;10:2053-74 pubmed publisher
Jiang L, Shan J, Tong X, Zhu H, Yang L, Zheng Q, et al. Cystic fibrosis transmembrane conductance regulator is correlated closely with sperm progressive motility and normal morphology in healthy and fertile men with normal sperm parameters. Andrologia. 2014;46:824-30 pubmed publisher
Monterisi S, Favia M, Guerra L, Cardone R, Marzulli D, Reshkin S, et al. CFTR regulation in human airway epithelial cells requires integrity of the actin cytoskeleton and compartmentalized cAMP and PKA activity. J Cell Sci. 2012;125:1106-17 pubmed publisher
Suaud L, Miller K, Alvey L, Yan W, Robay A, Kebler C, et al. ERp29 regulates DeltaF508 and wild-type cystic fibrosis transmembrane conductance regulator (CFTR) trafficking to the plasma membrane in cystic fibrosis (CF) and non-CF epithelial cells. J Biol Chem. 2011;286:21239-53 pubmed publisher
Powell M, Manandhar G, Spate L, Sutovsky M, Zimmerman S, Sachdev S, et al. Discovery of putative oocyte quality markers by comparative ExacTag proteomics. Proteomics Clin Appl. 2010;4:337-51 pubmed publisher
Li C, Jiang L, Chen W, Li K, Sheng H, Ni Y, et al. CFTR is essential for sperm fertilizing capacity and is correlated with sperm quality in humans. Hum Reprod. 2010;25:317-27 pubmed publisher
Favia M, Guerra L, Fanelli T, Cardone R, Monterisi S, Di Sole F, et al. Na+/H+ exchanger regulatory factor 1 overexpression-dependent increase of cytoskeleton organization is fundamental in the rescue of F508del cystic fibrosis transmembrane conductance regulator in human airway CFBE41o- cells. Mol Biol Cell. 2010;21:73-86 pubmed publisher
Chen W, Xu W, Chen Z, Ni Y, Yuan Y, Zhou S, et al. Cl- is required for HCO3- entry necessary for sperm capacitation in guinea pig: involvement of a Cl-/HCO3- exchanger (SLC26A3) and CFTR. Biol Reprod. 2009;80:115-23 pubmed publisher
Zheng W, Kuhlicke J, Jäckel K, Eltzschig H, Singh A, Sjöblom M, et al. Hypoxia inducible factor-1 (HIF-1)-mediated repression of cystic fibrosis transmembrane conductance regulator (CFTR) in the intestinal epithelium. FASEB J. 2009;23:204-13 pubmed publisher
Lovato V, Roesli C, Ahlskog J, Scheuermann J, Neri D. A monoclonal antibody prevents aggregation of the NBD1 domain of the cystic fibrosis transmembrane conductance regulator. Protein Eng Des Sel. 2007;20:607-14 pubmed
Xu W, Shi Q, Chen W, Zhou C, Ni Y, Rowlands D, et al. Cystic fibrosis transmembrane conductance regulator is vital to sperm fertilizing capacity and male fertility. Proc Natl Acad Sci U S A. 2007;104:9816-21 pubmed
product information
CatalogNumber :
ab2784
ItemName :
Anti-CFTR antibody [CF3]
Category :
Antibody
Host :
Mouse
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
CF3
Size :
100 µl
SpeciesSummary :
Chk, Gpig, Hu, Ms, Pig, Rat
Application Summary :
Flow Cyt, ICC/IF, IHC-P, Inhibition, IP, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK