This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-ds DNA antibody [35I9 DNA]
catalog :
ab27156
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
35I9 DNA
reactivity :
human, mouse, fruit fly
application :
immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, proximity ligation assay, dot blot, other
citations: 23
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 5f
Tan H, Yong Y, Xue Y, Liu H, Furihata T, Shankar E, et al. cGAS and DDX41-STING mediated intrinsic immunity spreads intercellularly to promote neuroinflammation in SOD1 ALS model. iScience. 2022;25:104404 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:800; loading ...; fig 5b
  • immunocytochemistry; human; 1:800; loading ...; fig 1c, s1h
Matsui H, Ito J, Matsui N, Uechi T, Onodera O, Kakita A. Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease. Nat Commun. 2021;12:3101 pubmed publisher
  • proximity ligation assay; human; loading ...; fig 4a
  • immunoprecipitation; human; loading ...; fig 4c
Oo J, Irmer B, Günther S, Warwick T, Palfi K, Izquierdo Ponce J, et al. ZNF354C is a transcriptional repressor that inhibits endothelial angiogenic sprouting. Sci Rep. 2020;10:19079 pubmed publisher
  • other; fruit fly ; 1:500; loading ...; fig 4e
Jiang Y, Lin S, Chen J, Tsai H, Hsieh T, Fu C. Electron tomographic analysis reveals ultrastructural features of mitochondrial cristae architecture which reflect energetic state and aging. Sci Rep. 2017;7:45474 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 4e
Gaston J, Cheradame L, Yvonnet V, Déas O, Poupon M, Judde J, et al. Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents. Oncotarget. 2016;7:77205-77224 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 3c
Wisnovsky S, Jean S, Kelley S. Mitochondrial DNA repair and replication proteins revealed by targeted chemical probes. Nat Chem Biol. 2016;12:567-73 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 7a
Singh R, Dagnino L. E2F1 interactions with hHR23A inhibit its degradation and promote DNA repair. Oncotarget. 2016;7:26275-92 pubmed publisher
Murayama T, Nakayama J, Jiang X, Miyata K, Morris A, Cai K, et al. Targeting DHX9 triggers tumor-intrinsic interferon response and replication stress in Small Cell Lung Cancer. Cancer Discov. 2024;: pubmed publisher
Lanna A, Vaz B, D Ambra C, Valvo S, Vuotto C, Chiurchi xf9 V, et al. An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory. Nat Cell Biol. 2022;24:1461-1474 pubmed publisher
Menendez D, Anand J, Murphy C, Bell W, Fu J, Slepushkina N, et al. Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity. Oncotarget. 2022;13:332-346 pubmed publisher
Yan Q, Wulfridge P, Doherty J, Fernandez Luna J, Real P, Tang H, et al. Proximity labeling identifies a repertoire of site-specific R-loop modulators. Nat Commun. 2022;13:53 pubmed publisher
Rai P, Janardhan K, Meacham J, Madenspacher J, Lin W, Karmaus P, et al. IRGM1 links mitochondrial quality control to autoimmunity. Nat Immunol. 2021;22:312-321 pubmed publisher
Saha S, Sun Y, Huang S, Baechler S, Pongor L, Agama K, et al. DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks. Cell Rep. 2020;33:108569 pubmed publisher
Zhang Y, Schroeder L, Lessard M, Kidd P, Chung J, Song Y, et al. Nanoscale subcellular architecture revealed by multicolor three-dimensional salvaged fluorescence imaging. Nat Methods. 2020;17:225-231 pubmed publisher
Moriyama M, Koshiba T, Ichinohe T. Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses. Nat Commun. 2019;10:4624 pubmed publisher
Wang S, Zhang C, Hasson D, Desai A, SenBanerjee S, Magnani E, et al. Epigenetic Compensation Promotes Liver Regeneration. Dev Cell. 2019;: pubmed publisher
Carrasco Salas Y, Malapert A, Sulthana S, Molcrette B, Chazot Franguiadakis L, Bernard P, et al. The extruded non-template strand determines the architecture of R-loops. Nucleic Acids Res. 2019;47:6783-6795 pubmed publisher
Sentürk Cetin N, Kuo C, Ribarska T, Li R, Costa I, Grummt I. Isolation and genome-wide characterization of cellular DNA:RNA triplex structures. Nucleic Acids Res. 2019;47:2306-2321 pubmed publisher
Inoue M, Nakashima R, Enomoto M, Koike Y, Zhao X, Yip K, et al. Plasma redox imbalance caused by albumin oxidation promotes lung-predominant NETosis and pulmonary cancer metastasis. Nat Commun. 2018;9:5116 pubmed publisher
Hartono S, Malapert A, Legros P, Bernard P, Chedin F, Vanoosthuyse V. The Affinity of the S9.6 Antibody for Double-Stranded RNAs Impacts the Accurate Mapping of R-Loops in Fission Yeast. J Mol Biol. 2018;430:272-284 pubmed publisher
Yuan L, Mao Y, Luo W, Wu W, Xu H, Wang X, et al. Palmitic acid dysregulates the Hippo-YAP pathway and inhibits angiogenesis by inducing mitochondrial damage and activating the cytosolic DNA sensor cGAS-STING-IRF3 signaling mechanism. J Biol Chem. 2017;292:15002-15015 pubmed publisher
Chernyavskaya Y, Mudbhary R, Zhang C, Tokarz D, Jacob V, Gopinath S, et al. Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling. Development. 2017;144:2925-2939 pubmed publisher
Aizawa S, Contu V, Fujiwara Y, Hase K, Kikuchi H, Kabuta C, et al. Lysosomal membrane protein SIDT2 mediates the direct uptake of DNA by lysosomes. Autophagy. 2017;13:218-222 pubmed publisher
product information
CatalogNumber :
ab27156
ItemName :
Anti-ds DNA antibody [35I9 DNA]
Category :
Antibody
Host :
Mouse
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
35I9 DNA
Size :
100 µg
Application Summary :
Dot, ELISA, ICC, ICC/IF, IHC-Fr
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
Stefan.Pritchard@abcam.com, eCommerce@abcam.com, Vicky.Yang@abcam.com
https://www.abcam.com
888-7722226
headquarters: UK