This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-MCM7 antibody [47DC141]
catalog :
ab2360
quantity :
500 µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
47DC141
reactivity :
human, mouse, rat, dogs
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 24
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 1d
Bai G, Smolka M, Schimenti J. Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent, microRNA-Assisted MCM2-7 Downregulation. PLoS Genet. 2016;12:e1005787 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2b
Dumit V, Kuttner V, Käppler J, Piera Velazquez S, Jimenez S, Bruckner Tuderman L, et al. Altered MCM protein levels and autophagic flux in aged and systemic sclerosis dermal fibroblasts. J Invest Dermatol. 2014;134:2321-2330 pubmed publisher
Drissi R, Chauvin A, McKenna A, Levesque D, Blais Brochu S, Jean D, et al. Destabilization of the MiniChromosome Maintenance (MCM) complex modulates the cellular response to DNA double strand breaks. Cell Cycle. 2018;17:2593-2609 pubmed publisher
Nishiyama A, Yamaguchi L, Sharif J, Johmura Y, Kawamura T, Nakanishi K, et al. Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication. Nature. 2013;502:249-53 pubmed publisher
Fristrup N, Birkenkamp Demtroder K, Reinert T, Sanchez Carbayo M, Segersten U, Malmstrom P, et al. Multicenter validation of cyclin D1, MCM7, TRIM29, and UBE2C as prognostic protein markers in non-muscle-invasive bladder cancer. Am J Pathol. 2013;182:339-49 pubmed publisher
Chuang C, Yang D, Bai G, Freeland A, Pruitt S, Schimenti J. Post-transcriptional homeostasis and regulation of MCM2-7 in mammalian cells. Nucleic Acids Res. 2012;40:4914-24 pubmed publisher
Myklebust M, Fluge Ø, Immervoll H, Skarstein A, Balteskard L, Bruland O, et al. Expression of DSG1 and DSC1 are prognostic markers in anal carcinoma patients. Br J Cancer. 2012;106:756-62 pubmed publisher
Nakaoka H, Nishiyama A, Saito M, Ishikawa F. Xenopus laevis Ctc1-Stn1-Ten1 (xCST) protein complex is involved in priming DNA synthesis on single-stranded DNA template in Xenopus egg extract. J Biol Chem. 2012;287:619-27 pubmed publisher
Myklebust M, Bruland O, Fluge Ø, Skarstein A, Balteskard L, Dahl O. MicroRNA-15b is induced with E2F-controlled genes in HPV-related cancer. Br J Cancer. 2011;105:1719-25 pubmed publisher
Hartford S, Luo Y, Southard T, Min I, Lis J, Schimenti J. Minichromosome maintenance helicase paralog MCM9 is dispensible for DNA replication but functions in germ-line stem cells and tumor suppression. Proc Natl Acad Sci U S A. 2011;108:17702-7 pubmed publisher
Kawabata T, Yamaguchi S, Buske T, Luebben S, Wallace M, Matise I, et al. A reduction of licensed origins reveals strain-specific replication dynamics in mice. Mamm Genome. 2011;22:506-17 pubmed publisher
Nishiyama A, Frappier L, M chali M. MCM-BP regulates unloading of the MCM2-7 helicase in late S phase. Genes Dev. 2011;25:165-75 pubmed publisher
McBee J, Yu L, Kinoshita Y, Uo T, Beyer R, Veenstra T, et al. Proteomic analysis of protein expression changes in a model of gliomagenesis. Proteomics Clin Appl. 2007;1:1485-98 pubmed publisher
Ota T, Clayton A, Minot D, Shridhar V, Hartmann L, Gilks C, et al. Minichromosome maintenance protein 7 as a potential prognostic factor for progression-free survival in high-grade serous carcinomas of the ovary. Mod Pathol. 2011;24:277-87 pubmed publisher
Chuang C, Wallace M, Abratte C, Southard T, Schimenti J. Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress. PLoS Genet. 2010;6:e1001110 pubmed publisher
Nicolas A, Alazard Dany N, Biollay C, Arata L, Jolinon N, Kuhn L, et al. Identification of rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments. J Virol. 2010;84:8871-87 pubmed publisher
Pillaire M, Selves J, Gordien K, Gourraud P, Gouraud P, Gentil C, et al. A 'DNA replication' signature of progression and negative outcome in colorectal cancer. Oncogene. 2010;29:876-87 pubmed publisher
van Dekken H, Tilanus H, Hop W, Dinjens W, Wink J, Vissers K, et al. Array comparative genomic hybridization, expression array, and protein analysis of critical regions on chromosome arms 1q, 7q, and 8p in adenocarcinomas of the gastroesophageal junction. Cancer Genet Cytogenet. 2009;189:37-42 pubmed publisher
Azizi A, Kang S, Freilinger A, Gruber Olipitz M, Chen W, Yang J, et al. Mitosis-dependent protein expression in neuroblastoma cell line N1E-115. J Proteome Res. 2008;7:3412-22 pubmed publisher
Yang J, Zhao J, Zhu Y, Xiong W, Lin J, Ma X. Identification of candidate cancer genes involved in human retinoblastoma by data mining. Childs Nerv Syst. 2008;24:893-900 pubmed publisher
Bruland O, Fluge O, Immervoll H, Balteskard L, Myklebust M, Skarstein A, et al. Gene expression reveals two distinct groups of anal carcinomas with clinical implications. Br J Cancer. 2008;98:1264-73 pubmed publisher
Lim J, Wolpaw A, Caldwell M, Hladky S, Barrand M. Neural precursor cell influences on blood-brain barrier characteristics in rat brain endothelial cells. Brain Res. 2007;1159:67-76 pubmed
Rolland A, Evrard B, Guitton N, Lavigne R, Calvel P, Couvet M, et al. Two-dimensional fluorescence difference gel electrophoresis analysis of spermatogenesis in the rat. J Proteome Res. 2007;6:683-97 pubmed
Shima N, Alcaraz A, Liachko I, Buske T, Andrews C, Munroe R, et al. A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice. Nat Genet. 2007;39:93-8 pubmed
product information
CatalogNumber :
ab2360
ItemName :
Anti-MCM7 antibody [47DC141]
Product Type :
Antibody
Host Species :
Mouse
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
47DC141
Size :
500 µl
SpeciesSummary :
Dog, Hu, Ms, Rat, Xl
Purity :
IgG fraction
Application Summary :
Flow Cyt, ICC/IF, IHC-P, IP, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK