This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Ascent Scientific
product type :
antibody
product name :
XPA antibody [12F5]
catalog :
ab2352
quantity :
500 ul
clonality :
monoclonal
host :
mouse
clone name :
12F5
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
citations: 9
Published Application/Species/DilutionReference
  • western blot (knockout validation); human; 1:100; fig 2
Sassa A, Kamoshita N, Kanemaru Y, Honma M, Yasui M. Xeroderma Pigmentosum Group A Suppresses Mutagenesis Caused by Clustered Oxidative DNA Adducts in the Human Genome. PLoS ONE. 2015;10:e0142218 pubmed publisher
  • western blot; human; 0.1 ug/ml
Rossner P, Mrhalkova A, Uhlirova K, Spatova M, Rossnerova A, Libalova H, et al. Nucleotide excision repair is not induced in human embryonic lung fibroblasts treated with environmental pollutants. PLoS ONE. 2013;8:e69197 pubmed publisher
Herrera-Moyano E, Moriel-Carretero M, Montelone B, Aguilera A. The rem mutations in the ATP-binding groove of the Rad3/XPD helicase lead to Xeroderma pigmentosum-Cockayne syndrome-like phenotypes. PLoS Genet. 2014;10:e1004859 pubmed publisher
Gilljam K, Müller R, Liabakk N, Otterlei M. Nucleotide excision repair is associated with the replisome and its efficiency depends on a direct interaction between XPA and PCNA. PLoS ONE. 2012;7:e49199 pubmed publisher
Gueranger Q, Kia A, Frith D, Karran P. Crosslinking of DNA repair and replication proteins to DNA in cells treated with 6-thioguanine and UVA. Nucleic Acids Res. 2011;39:5057-66 pubmed publisher
King B, Cooper K, Liu K, Hudson L. Poly(ADP-ribose) contributes to an association between poly(ADP-ribose) polymerase-1 and xeroderma pigmentosum complementation group A in nucleotide excision repair. J Biol Chem. 2012;287:39824-33 pubmed publisher
Shen S, Lee J, Weinfeld M, Le X. Attenuation of DNA damage-induced p53 expression by arsenic: a possible mechanism for arsenic co-carcinogenesis. Mol Carcinog. 2008;47:508-18 pubmed
Overmeer R, Moser J, Volker M, Kool H, Tomkinson A, Van Zeeland A, et al. Replication protein A safeguards genome integrity by controlling NER incision events. J Cell Biol. 2011;192:401-15 pubmed publisher
Luijsterburg M, Dinant C, Lans H, Stap J, Wiernasz E, Lagerwerf S, et al. Heterochromatin protein 1 is recruited to various types of DNA damage. J Cell Biol. 2009;185:577-86 pubmed publisher
product information
Catalog Number :
ab2352
Product Name :
XPA antibody [12F5]
Host Species :
Mouse
Clonality :
monoclonal
Product Type :
Primary antibodies
Size :
500 ul
SwissProtID :
P23025
Isotype :
IgG2a
CrossReactivity :
Reacts with: Human.
Application Summary :
ICC/IF, IHC-Fr, IHC-P, WB
company information
Abcam
330 Cambridge Science Park
Cambridge
CB4 0FL UK
orders@abcam.com
44 (0)1223 696000

1 Kendall Square, Ste 341
Cambridge, MA 02139-1517
USA
us.orders@abcam.com
617 225 2272, 888-77-ABCAM (22226)

www.abcam.com
888-7722226
headquarters: UK