| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; fig 3
| Labrousse Arias D, Castillo González R, Rogers N, Torres Capelli M, Barreira B, Aragonés J, et al. HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction. Cardiovasc Res. 2016;109:115-30 pubmed publisher |
- western blot; human; loading ...; fig s8
| Zhang M, Cui J, Lee D, Yuen V, Chiu D, Goh C, et al. Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer. Nat Commun. 2022;13:954 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig 4e
| Chi Y, Remšík J, Kiseliovas V, Derderian C, Sener U, Alghader M, et al. Cancer cells deploy lipocalin-2 to collect limiting iron in leptomeningeal metastasis. Science. 2020;369:276-282 pubmed publisher |
- western blot; mouse; 1:500; loading ...; fig 5e
| Sala M, Chen C, Zhang Q, Do Umehara H, Wu W, Misharin A, et al. JNK2 up-regulates hypoxia-inducible factors and contributes to hypoxia-induced erythropoiesis and pulmonary hypertension. J Biol Chem. 2018;293:271-284 pubmed publisher |
- western blot; mouse; loading ...; fig 4a
| Myllymäki M, Määttä J, Dimova E, Izzi V, Väisänen T, Myllyharju J, et al. Notch Downregulation and Extramedullary Erythrocytosis in Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2-Deficient Mice. Mol Cell Biol. 2017;37: pubmed publisher |
- chromatin immunoprecipitation; human; fig 4d
- western blot; human; loading ...; fig 4f
| Ramakrishnan S, Ku S, Ciamporcero E, Miles K, Attwood K, Chintala S, et al. HDAC 1 and 6 modulate cell invasion and migration in clear cell renal cell carcinoma. BMC Cancer. 2016;16:617 pubmed publisher |
- western blot; human; 1:500; loading ...; fig 4e
| Bourseau Guilmain E, Menard J, Lindqvist E, Indira Chandran V, Christianson H, Cerezo Magaña M, et al. Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells. Nat Commun. 2016;7:11371 pubmed publisher |
| Hu J, Smith D, Wu L. VHL L169P Variant Does Not Alter Cellular Hypoxia Tension in Clear Cell Renal Cell Carcinoma. Int J Mol Sci. 2023;24: pubmed publisher |
| Nassar A, Abou Alaiwi S, Baca S, Adib E, Corona R, Seo J, et al. Epigenomic charting and functional annotation of risk loci in renal cell carcinoma. Nat Commun. 2023;14:346 pubmed publisher |
| Niklasson C, Fredlund E, Monni E, Lindvall J, Kokaia Z, Hammarlund E, et al. Hypoxia inducible factor-2α importance for migration, proliferation, and self-renewal of trunk neural crest cells. Dev Dyn. 2021;250:191-236 pubmed publisher |
| Grassi E, Jeannot P, Pantazopoulou V, Berg T, Pietras A. Niche-derived soluble DLK1 promotes glioma growth. Neoplasia. 2020;22:689-701 pubmed publisher |
| Wang H, Cui J, Yang C, Rosenblum J, Zhang Q, Song Q, et al. A Transgenic Mouse Model of Pacak⁻Zhuang Syndrome with An Epas1 Gain-of-Function Mutation. Cancers (Basel). 2019;11: pubmed publisher |
| Vendrov A, Sumida A, Canugovi C, Lozhkin A, Hayami T, Madamanchi N, et al. NOXA1-dependent NADPH oxidase regulates redox signaling and phenotype of vascular smooth muscle cell during atherogenesis. Redox Biol. 2019;21:101063 pubmed publisher |
| Cai X, Zhang D, Wang J, Liu X, Ouyang G, Xiao W. Deletion of the fih gene encoding an inhibitor of hypoxia-inducible factors increases hypoxia tolerance in zebrafish. J Biol Chem. 2018;293:15370-15380 pubmed publisher |
| Rodrigues P, Patel S, Harewood L, Olan I, Vojtasova E, Syafruddin S, et al. NF-κB-Dependent Lymphoid Enhancer Co-option Promotes Renal Carcinoma Metastasis. Cancer Discov. 2018;8:850-865 pubmed publisher |
| Serocki M, Bartoszewska S, Janaszak Jasiecka A, Ochocka R, Collawn J, Bartoszewski R. miRNAs regulate the HIF switch during hypoxia: a novel therapeutic target. Angiogenesis. 2018;21:183-202 pubmed publisher |
| Westerlund I, Shi Y, Toskas K, Fell S, Li S, Surova O, et al. Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression. Proc Natl Acad Sci U S A. 2017;114:E6137-E6146 pubmed publisher |
| Zhu C, Yu J, Pan Q, Yang J, Hao G, Wang Y, et al. Hypoxia-inducible factor-2 alpha promotes the proliferation of human placenta-derived mesenchymal stem cells through the MAPK/ERK signaling pathway. Sci Rep. 2016;6:35489 pubmed publisher |
| Yaghi L, Poras I, Simões R, Donadi E, Tost J, Daunay A, et al. Hypoxia inducible factor-1 mediates the expression of the immune checkpoint HLA-G in glioma cells through hypoxia response element located in exon 2. Oncotarget. 2016;7:63690-63707 pubmed publisher |
| Alam M, Persson C, Reinbothe S, Kazi J, Rönnstrand L, Wigerup C, et al. HIF2α contributes to antiestrogen resistance via positive bilateral crosstalk with EGFR in breast cancer cells. Oncotarget. 2016;7:11238-50 pubmed publisher |
| Stiehl D, Bordoli M, Abreu Rodríguez I, Wollenick K, Schraml P, Gradin K, et al. Non-canonical HIF-2? function drives autonomous breast cancer cell growth via an AREG-EGFR/ErbB4 autocrine loop. Oncogene. 2012;31:2283-97 pubmed publisher |
