This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Rabbit polyclonal to Bcl-2
catalog :
ab196495
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
citations: 40
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:100; loading ...
Gao H, Sun H, Yan N, Zhao P, Xu H, Zheng W, et al. ATP13A2 Declines Zinc-Induced Accumulation of α-Synuclein in a Parkinson's Disease Model. Int J Mol Sci. 2022;23: pubmed publisher
  • western blot; rat; 1:100; loading ...; fig 5c
Zhou F, Zou X, Zhang J, Wang Z, Yang Y, Wang D. Jian-Pi-Yi-Shen Formula Ameliorates Oxidative Stress, Inflammation, and Apoptosis by Activating the Nrf2 Signaling in 5/6 Nephrectomized Rats. Front Pharmacol. 2021;12:630210 pubmed publisher
  • western blot; rat; 1:2000; fig 5f
Meng L, Teng X, Liu Y, Yang C, Wang S, Yuan W, et al. Vital Roles of Gremlin-1 in Pulmonary Arterial Hypertension Induced by Systemic-to-Pulmonary Shunts. J Am Heart Assoc. 2020;9:e016586 pubmed publisher
  • western blot; human; loading ...; fig 2e
Xiang Q, Kang L, Wang J, Liao Z, Song Y, Zhao K, et al. CircRNA-CIDN mitigated compression loading-induced damage in human nucleus pulposus cells via miR-34a-5p/SIRT1 axis. EBioMedicine. 2020;53:102679 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 1e, 2c, 5g
Hou K, Li G, Zhao J, Xu B, Zhang Y, Yu J, et al. Bone mesenchymal stem cell-derived exosomal microRNA-29b-3p prevents hypoxic-ischemic injury in rat brain by activating the PTEN-mediated Akt signaling pathway. J Neuroinflammation. 2020;17:46 pubmed publisher
  • western blot; rat; 1:1200; loading ...; fig 5b
Li J, Liu Z, Wang L, Xu H, Wang Y. Thousand and one kinase 1 protects MCAO-induced cerebral ischemic stroke in rats by decreasing apoptosis and pro-inflammatory factors. Biosci Rep. 2019;39: pubmed publisher
  • western blot; mouse; loading ...; fig 4d
Liu F, Fan D, Yang Z, Tang N, Guo Z, Ma S, et al. TLR9 is essential for HMGB1-mediated post-myocardial infarction tissue repair through affecting apoptosis, cardiac healing, and angiogenesis. Cell Death Dis. 2019;10:480 pubmed publisher
  • western blot; human; loading ...; fig 1c
Zhao J, Sun H, Zhang J, Wang M, Du X, Zhang J. Long non-coding RNA ANRIL down-regulates microRNA-7 to protect human trabecular meshwork cells in an experimental model for glaucoma. Eur Rev Med Pharmacol Sci. 2019;23:3173-3182 pubmed publisher
  • western blot; rat; 1:750; loading ...; fig 3a
Singh A, Agrahari A, Singh R, Yadav S, Srivastava V, Parmar D. Imprinting of cerebral cytochrome P450s in offsprings prenatally exposed to cypermethrin augments toxicity on rechallenge. Sci Rep. 2016;6:37426 pubmed publisher
Lyu J, Li Z, Roberts J, Qi Y, Xiong J. The short-chain fatty acid acetate coordinates with CD30 to modulate T-cell survival. Mol Biol Cell. 2023;34:br11 pubmed publisher
Huang R, Shi C, Liu G. Long noncoding RNA ACART knockdown decreases 3T3-L1 preadipocyte proliferation and differentiation. Open Life Sci. 2023;18:20220552 pubmed publisher
Wang A, Chen Y, Shi L, Li M, Li L, Wang S, et al. Tumor-suppressive MEG3 induces microRNA-493-5p expression to reduce arabinocytosine chemoresistance of acute myeloid leukemia cells by downregulating the METTL3/MYC axis. J Transl Med. 2022;20:288 pubmed publisher
Lei M, Ke G, Wang Y, Luo D, Hu Y. Long non-coding RNA TUG1 sponges microRNA-9 to protect podocytes from high glucose-induced apoptosis and mitochondrial dysfunction via SIRT1 upregulation. Exp Ther Med. 2022;23:236 pubmed publisher
Zhang W, Hong J, Zhang H, Zheng W, Yang Y. Astrocyte-derived exosomes protect hippocampal neurons after traumatic brain injury by suppressing mitochondrial oxidative stress and apoptosis. Aging (Albany NY). 2021;13:21642-21658 pubmed publisher
Xiao X, Li W, Rong D, Xu Z, Zhang Z, Ye H, et al. Human umbilical cord mesenchymal stem cells-derived extracellular vesicles facilitate the repair of spinal cord injury via the miR-29b-3p/PTEN/Akt/mTOR axis. Cell Death Discov. 2021;7:212 pubmed publisher
Zhang W, Hong J, Zheng W, Liu A, Yang Y. High glucose exacerbates neuroinflammation and apoptosis at the intermediate stage after post-traumatic brain injury. Aging (Albany NY). 2021;13:16088-16104 pubmed publisher
Li T, Han Y, Guo B, Chen P, Wan Y, Ye B. Sevoflurane protects against ischemia-reperfusion injury in mice after total knee arthroplasty via facilitating RASD1-mediated protein kinase A pathway activation. Aging (Albany NY). 2021;13:13333-13348 pubmed publisher
Li T, Chen Y, Li Y, Yao Z, Liu W. FAM134B-mediated endoplasmic reticulum autophagy protects against sepsis myocardial injury in mice. Aging (Albany NY). 2021;13:13535-13547 pubmed publisher
Li H, He L, Tuo Y, Huang Y, Qian B. Circular RNA hsa_circ_0000282 contributes to osteosarcoma cell proliferation by regulating miR-192/XIAP axis. BMC Cancer. 2020;20:1026 pubmed publisher
Du S, Shao J, Qi Y, Liu X, Liu J, Zhang F. Long non-coding RNA ANRIL alleviates H2O2-induced injury by up-regulating microRNA-21 in human lens epithelial cells. Aging (Albany NY). 2020;12:6543-6557 pubmed publisher
Xia R, Chen J, Gao J, Luo X, Ke C, Ren C, et al. Inhibition of esophageal-carcinoma cell proliferation by genistein via suppression of JAK1/2-STAT3 and AKT/MDM2/p53 signaling pathways. Aging (Albany NY). 2020;12:6240-6259 pubmed publisher
Xu L, Xu Q, Xu F, Zhang W, Chen Q, Wu H, et al. MicroRNA-325-3p prevents sevoflurane-induced learning and memory impairment by inhibiting Nupr1 and C/EBPβ/IGFBP5 signaling in rats. Aging (Albany NY). 2020;12:5209-5220 pubmed publisher
Yang W, Cui G, Ding M, Yang M, Dai D. MicroRNA-124-3p.1 promotes cell proliferation through Axin1-dependent Wnt signaling pathway and predicts a poor prognosis of triple-negative breast cancer. J Clin Lab Anal. 2020;:e23266 pubmed publisher
Mi B, Xiong Y, Chen L, Yan C, Endo Y, Liu Y, et al. CircRNA AFF4 promotes osteoblast cells proliferation and inhibits apoptosis via the Mir-7223-5p/PIK3R1 axis. Aging (Albany NY). 2019;11:11988-12001 pubmed publisher
Li J, Dai X, He X, Yang R, Xia Z, Xiao H. Effect of SOD2 methylation on mitochondrial DNA4834-bp deletion mutation in marginal cells under oxidative stress. Bosn J Basic Med Sci. 2020;20:70-77 pubmed publisher
Wang F, Zhao L, Shan Y, Li R, Qin G. CTRP3 Protects against High Glucose-Induced Cell Injury in Human Umbilical Vein Endothelial Cells. Anal Cell Pathol (Amst). 2019;2019:7405602 pubmed publisher
Qian L, Pan S, Shi L, Zhou Y, Sun L, Wan Z, et al. Downregulation of microRNA-218 is cardioprotective against cardiac fibrosis and cardiac function impairment in myocardial infarction by binding to MITF. Aging (Albany NY). 2019;11:5368-5388 pubmed publisher
Qiang J, Lv T, Wu Z, Yang X. Down-regulation of microRNA-142-3p inhibits the aggressive phenotypes of rheumatoid arthritis fibroblast-like synoviocytes through inhibiting nuclear factor-κB signaling. Biosci Rep. 2019;39: pubmed publisher
Chen X, Chen S, Liang W, Ba F. Administration of Repetitive Transcranial Magnetic Stimulation Attenuates Aβ1-42-Induced Alzheimer's Disease in Mice by Activating β-Catenin Signaling. Biomed Res Int. 2019;2019:1431760 pubmed publisher
He M, Sun H, Pang J, Guo X, Huo Y, Wu X, et al. Propofol alleviates hypoxia-induced nerve injury in PC-12 cells by up-regulation of microRNA-153. BMC Anesthesiol. 2018;18:197 pubmed publisher
Chu Y, Fang Y, Chi J, Li J, Zhang D, Zou Y, et al. Astragalus polysaccharides decrease proliferation, migration, and invasion but increase apoptosis of human osteosarcoma cells by up-regulation of microRNA-133a. Braz J Med Biol Res. 2018;51:e7665 pubmed publisher
Xiong Y, Huang H, Chen S, Dai H, Zhang L. ERK5‑regulated RERG expression promotes cancer progression in prostatic carcinoma. Oncol Rep. 2019;41:1160-1168 pubmed publisher
Su Y, Lu J, Gong P, Chen X, Liang C, Zhang J. Rapamycin induces autophagy to alleviate acute kidney injury following cerebral ischemia and reperfusion via the mTORC1/ATG13/ULK1 signaling pathway. Mol Med Rep. 2018;18:5445-5454 pubmed publisher
Zeng Q, He H, Wang X, Zhou Y, Lin H, Tan Z, et al. Electroacupuncture Preconditioning Improves Myocardial Infarction Injury via Enhancing AMPK-Dependent Autophagy in Rats. Biomed Res Int. 2018;2018:1238175 pubmed publisher
Chen K, Sun Y, Diao Y, Zhang T, Dong W. Hydrogen-rich solution attenuates myocardial injury caused by cardiopulmonary bypass in rats via the Janus-activated kinase 2/signal transducer and activator of transcription 3 signaling pathway. Oncol Lett. 2018;16:167-178 pubmed publisher
Wang S, Lei Y, Cai Z, Ye X, Li L, Luo X, et al. Girdin regulates the proliferation and apoptosis of pancreatic cancer cells via the PI3K/Akt signalling pathway. Oncol Rep. 2018;40:599-608 pubmed publisher
Zhao X, Zhang C, Le Z, Zeng S, Pan C, Shi J, et al. Telomerase reverse transcriptase interference synergistically promotes tumor necrosis factor‑related apoptosis‑inducing ligand‑induced oral squamous cell carcinoma apoptosis and suppresses proliferation in vitro and in vivo. Int J Mol Med. 2018;42:1283-1294 pubmed publisher
Ren K, Yong C, Yuan H, Cao B, Zhao K, Wang J. TNF-? inhibits SCF, ghrelin, and substance P expressions through the NF-?B pathway activation in interstitial cells of Cajal. Braz J Med Biol Res. 2018;51:e7065 pubmed publisher
Ding N, Sun X, Wang T, Huang L, Wen J, Zhou Y. miR‑378a‑3p exerts tumor suppressive function on the tumorigenesis of esophageal squamous cell carcinoma by targeting Rab10. Int J Mol Med. 2018;42:381-391 pubmed publisher
Huang N, Li W, Wang X, Qi S. MicroRNA-17-5p aggravates lipopolysaccharide-induced injury in nasal epithelial cells by targeting Smad7. BMC Cell Biol. 2018;19:1 pubmed publisher
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
Stefan.Pritchard@abcam.com, eCommerce@abcam.com, Vicky.Yang@abcam.com
https://www.abcam.com
888-7722226
headquarters: UK