This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-Oct4 antibody
catalog :
ab18976
quantity :
100 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 23
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 2a
Abdelaziz L, Ebian H, Harb O, Nosery Y, Taha H, Nawar N. Clinical significance of cytokeratin 19 and OCT4 as survival markers in non-metastatic and metastatic breast cancer patients. Contemp Oncol (Pozn). 2022;26:78-87 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 6b, s12f
  • western blot; human; loading ...; fig 6i, s14d
Kaushal K, Kim E, Tyagi A, Karapurkar J, Haq S, Jung H, et al. Genome-wide screening for deubiquitinase subfamily identifies ubiquitin-specific protease 49 as a novel regulator of odontogenesis. Cell Death Differ. 2022;: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 6c
Fleming Martinez A, D xf6 ppler H, Bastea L, Edenfield B, Patel T, Leitges M, et al. Dysfunctional EGFR and oxidative stress-induced PKD1 signaling drive formation of DCLK1+ pancreatic stem cells. iScience. 2021;24:102019 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2g
Surendran H, Nandakumar S, Reddy K V, Stoddard J, Mohan K V, Upadhyay P, et al. Transplantation of retinal pigment epithelium and photoreceptors generated concomitantly via small molecule-mediated differentiation rescues visual function in rodent models of retinal degeneration. Stem Cell Res Ther. 2021;12:70 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 1b
  • western blot; human; 1:1000; loading ...; fig 1c
Jiang Z, Zhang C, Liu X, Ma X, Bian X, Xiao X, et al. Dexamethasone inhibits stemness maintenance and enhances chemosensitivity of hepatocellular carcinoma stem cells by inducing deSUMOylation of HIF‑1α and Oct4. Int J Oncol. 2020;57:780-790 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 4a
Li W, Zhang N, Jin C, Long M, Rajabi H, Yasumizu Y, et al. MUC1-C drives stemness in progression of colitis to colorectal cancer. JCI Insight. 2020;5: pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 8f
Espinoza Sánchez N, Enciso J, Pelayo R, Fuentes Panana E. An NF?B-dependent mechanism of tumor cell plasticity and lateral transmission of aggressive features. Oncotarget. 2018;9:26679-26700 pubmed publisher
  • flow cytometry; mouse; fig s2c
  • immunocytochemistry; mouse; 1:300; fig s2c
Wang X, Hodgkinson C, Lu K, Payne A, Pratt R, Dzau V. Selenium Augments microRNA Directed Reprogramming of Fibroblasts to Cardiomyocytes via Nanog. Sci Rep. 2016;6:23017 pubmed publisher
  • western blot; mouse; 1:1000; fig 6
Hammoud A, Kirstein N, Mournetas V, Darracq A, Broc S, Blanchard C, et al. Murine Embryonic Stem Cell Plasticity Is Regulated through Klf5 and Maintained by Metalloproteinase MMP1 and Hypoxia. PLoS ONE. 2016;11:e0146281 pubmed publisher
Palomino Lago E, Jelbert E, Baird A, Lam P, Guest D. Equine induced pluripotent stem cells are responsive to inflammatory cytokines before and after differentiation into musculoskeletal cell types. In Vitro Cell Dev Biol Anim. 2023;59:514-527 pubmed publisher
Karapurkar J, Kim M, Colaco J, Suresh B, Sarodaya N, Kim D, et al. CRISPR/Cas9-based genome-wide screening of the deubiquitinase subfamily identifies USP3 as a protein stabilizer of REST blocking neuronal differentiation and promotes neuroblastoma tumorigenesis. J Exp Clin Cancer Res. 2023;42:121 pubmed publisher
Xu M, Zhao Y, Zhang W, Geng M, Liu Q, Gao Q, et al. Genome-scale screening in a rat haploid system identifies Thop1 as a modulator of pluripotency exit. Cell Prolif. 2022;55:e13209 pubmed publisher
Rhie B, Antao A, Karapurkar J, Kim M, Jo W, Ramakrishna S, et al. Ubiquitin-Specific Protease 3 Deubiquitinates and Stabilizes Oct4 Protein in Human Embryonic Stem Cells. Int J Mol Sci. 2021;22: pubmed publisher
Kim E, Kim Y, Lee H, Jeong S, Nam H, Cho J. Upregulation of Peroxiredoxin-2 in Well-Differentiated Pancreatic Neuroendocrine Tumors and Its Utility as a Biomarker for Predicting the Response to Everolimus. Antioxidants (Basel). 2020;9: pubmed publisher
Utnal P, A H, Pn S, Gn M. Expression of CD 133 in Invasive Ductal Carcinoma of Breast. Asian Pac J Cancer Prev. 2020;21:3055-3059 pubmed publisher
Chao X, Yi L, Lan L, Wei H, Wei D. Long-term PM2.5 exposure increases the risk of non-small cell lung cancer (NSCLC) progression by enhancing interleukin-17a (IL-17a)-regulated proliferation and metastasis. Aging (Albany NY). 2020;12:11579-11602 pubmed publisher
Dergilev K, Tsokolaeva Z, Makarevich P, Beloglazova I, Zubkova E, Boldyreva M, et al. C-Kit Cardiac Progenitor Cell Based Cell Sheet Improves Vascularization and Attenuates Cardiac Remodeling following Myocardial Infarction in Rats. Biomed Res Int. 2018;2018:3536854 pubmed publisher
Hildebrandt T, Hermes R, Colleoni S, Diecke S, Holtze S, Renfree M, et al. Embryos and embryonic stem cells from the white rhinoceros. Nat Commun. 2018;9:2589 pubmed publisher
Su X, Wu C, Ye X, Zeng M, Zhang Z, Che Y, et al. Embryonic lethality in mice lacking Trim59 due to impaired gastrulation development. Cell Death Dis. 2018;9:302 pubmed publisher
Yang Y, Liu B, Xu J, Wang J, Wu J, Shi C, et al. Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency. Cell. 2017;169:243-257.e25 pubmed publisher
Xiao L, Song Y, Huang W, Yang S, Fu J, Feng X, et al. Expression of SOX2, NANOG and OCT4 in a mouse model of lipopolysaccharide-induced acute uterine injury and intrauterine adhesions. Reprod Biol Endocrinol. 2017;15:14 pubmed publisher
Cao Z, Hong R, Ding B, Zuo X, Li H, Ding J, et al. TSA and BIX-01294 Induced Normal DNA and Histone Methylation and Increased Protein Expression in Porcine Somatic Cell Nuclear Transfer Embryos. PLoS ONE. 2017;12:e0169092 pubmed publisher
Neri T, Muggeo S, Paulis M, Caldana M, Crisafulli L, Strina D, et al. Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts. Stem Cell Reports. 2015;5:558-68 pubmed publisher
product information
CatalogNumber :
ab18976
ItemName :
Anti-Oct4 antibody
Category :
Antibody
Host :
Rabbit
Clonality :
Polyclonal
Conjugate :
Unconjugated
Size :
100 µg
SpeciesSummary :
Hu, Mcq, Ms, Pig, Rat
Application Summary :
Flow Cyt, ICC/IF, IHC-Fr, IHC-P, IP, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
Stefan.Pritchard@abcam.com, eCommerce@abcam.com, Vicky.Yang@abcam.com
https://www.abcam.com
888-7722226
headquarters: UK