This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-ATF-4 antibody [EPR18111]
catalog :
ab184909
quantity :
10 µl, 100 µl
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
EPR18111
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig 1a
Chu H, Peterson C, Chamling X, Berlinicke C, Zack D, Jun A, et al. Integrated Stress Response Regulation of Corneal Epithelial Cell Motility and Cytokine Production. Invest Ophthalmol Vis Sci. 2022;63:1 pubmed publisher
  • western blot; human; loading ...; fig 2a
Zhang J, Terán G, Popa M, Madapura H, Ladds M, Lianoudaki D, et al. DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance. iScience. 2021;24:102494 pubmed publisher
  • western blot; human; loading ...; fig 4h
Ma L, Chen T, Zhang X, Miao Y, Tian X, Yu K, et al. The m6A reader YTHDC2 inhibits lung adenocarcinoma tumorigenesis by suppressing SLC7A11-dependent antioxidant function. Redox Biol. 2021;38:101801 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 2b
Arai S, Varkaris A, Nouri M, Chen S, Xie L, Balk S. MARCH5 mediates NOXA-dependent MCL1 degradation driven by kinase inhibitors and integrated stress response activation. elife. 2020;9: pubmed publisher
  • western blot; human; loading ...; fig s5f
Clementi E, Inglin L, Beebe E, Gsell C, Garajova Z, Markkanen E. Persistent DNA damage triggers activation of the integrated stress response to promote cell survival under nutrient restriction. BMC Biol. 2020;18:36 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1b
Soiberman U, Shehata A, Lu M, Young T, Daoud Y, Chakravarti S, et al. Small Molecule Modulation of the Integrated Stress Response Governs the Keratoconic Phenotype In Vitro. Invest Ophthalmol Vis Sci. 2019;60:3422-3431 pubmed publisher
Gouveia Roque C, Chung K, McCurdy E, Jagannathan R, Randolph L, Herline Killian K, et al. CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer's disease gene expression linked to neuropathology. Sci Adv. 2023;9:eadd2671 pubmed publisher
Zhang Y, Huynh Dam K, Ding X, Sikirzhytski V, Lim C, Broude E, et al. RASSF1 is identified by transcriptome coordination analysis as a target of ATF4. FEBS Open Bio. 2023;13:556-569 pubmed publisher
Lu S, Wang X, He C, Wang L, Liang S, Wang C, et al. ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and iron. Acta Pharmacol Sin. 2021;42:1690-1702 pubmed publisher
Kong Z, Zhou C, Kang J, Tan Z. Comparison of the Effects of Nonprotein and Protein Nitrogen on Apoptosis and Autophagy of Rumen Epithelial Cells in Goats. Animals (Basel). 2020;10: pubmed publisher
McLaughlin M, Pedersen M, Roulstone V, Bergerhoff K, Smith H, Whittock H, et al. The PERK Inhibitor GSK2606414 Enhances Reovirus Infection in Head and Neck Squamous Cell Carcinoma via an ATF4-Dependent Mechanism. Mol Ther Oncolytics. 2020;16:238-249 pubmed publisher
Liu Z, Gu H, Gan L, Xu Y, Feng F, Saeed M, et al. Reducing Smad3/ATF4 was essential for Sirt1 inhibiting ER stress-induced apoptosis in mice brown adipose tissue. Oncotarget. 2017;8:9267-9279 pubmed publisher
product information
CatalogNumber :
ab184909
ItemName :
Anti-ATF-4 antibody [EPR18111]
Category :
Antibody
Host :
Rabbit
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
EPR18111
Size :
10 µl, 100 µl
SpeciesSummary :
Hu
Application Summary :
Flow Cyt, ICC/IF, IHC-P, IP, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK