This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-xCT antibody [EPR8290(2)]
catalog :
ab175186
quantity :
10 µl, 100 µl
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
EPR8290(2)
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 6b
  • immunohistochemistry - paraffin section; rat; 1:200; loading ...; fig 8b
Zhao Y, Du Y, Gao Y, Xu Z, Zhao D, Yang M. ATF3 Regulates Osteogenic Function by Mediating Osteoblast Ferroptosis in Type 2 Diabetic Osteoporosis. Dis Markers. 2022;2022:9872243 pubmed publisher
  • western blot; rat; loading ...; fig 4a, 4c
Chang B, Guan H, Wang X, Chen Z, Zhu W, Wei X, et al. Cox4i2 Triggers an Increase in Reactive Oxygen Species, Leading to Ferroptosis and Apoptosis in HHV7 Infected Schwann Cells. Front Mol Biosci. 2021;8:660072 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 4c
  • western blot; human; loading ...; fig s4f
Ma L, Chen T, Zhang X, Miao Y, Tian X, Yu K, et al. The m6A reader YTHDC2 inhibits lung adenocarcinoma tumorigenesis by suppressing SLC7A11-dependent antioxidant function. Redox Biol. 2021;38:101801 pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 3e
Charles Messance H, Blot G, Couturier A, Vignaud L, Touhami S, Beguier F, et al. IL-1β induces rod degeneration through the disruption of retinal glutamate homeostasis. J Neuroinflammation. 2020;17:1 pubmed publisher
  • western blot; rat; loading ...; fig 6a
  • western blot; human; loading ...; fig 6a
Wang Z, Ding Y, Wang X, Lu S, Wang C, He C, et al. Pseudolaric acid B triggers ferroptosis in glioma cells via activation of Nox4 and inhibition of xCT. Cancer Lett. 2018;428:21-33 pubmed publisher
Lu S, Wang X, He C, Wang L, Liang S, Wang C, et al. ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and iron. Acta Pharmacol Sin. 2021;42:1690-1702 pubmed publisher
Ma L, Zhang X, Yu K, Xu X, Chen T, Shi Y, et al. Targeting SLC3A2 subunit of system XC- is essential for m6A reader YTHDC2 to be an endogenous ferroptosis inducer in lung adenocarcinoma. Free Radic Biol Med. 2021;168:25-43 pubmed publisher
Wu P, Li C, Ye D, Yu K, Li Y, Tang H, et al. Circular RNA circEPSTI1 accelerates cervical cancer progression via miR-375/409-3P/515-5p-SLC7A11 axis. Aging (Albany NY). 2021;13:4663-4673 pubmed publisher
Ogiwara H, Takahashi K, Sasaki M, Kuroda T, Yoshida H, Watanabe R, et al. Targeting the Vulnerability of Glutathione Metabolism in ARID1A-Deficient Cancers. Cancer Cell. 2019;35:177-190.e8 pubmed publisher
Suárez Pozos E, Martínez Lozada Z, Méndez Flores O, Guillem A, Hernández Kelly L, Castelán F, et al. Characterization of the cystine/glutamate antiporter in cultured Bergmann glia cells. Neurochem Int. 2017;108:52-59 pubmed publisher
product information
CatalogNumber :
ab175186
ItemName :
Anti-xCT antibody [EPR8290(2)]
Category :
Antibody
Host :
Rabbit
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
EPR8290(2)
Size :
10 µl, 100 µl
SpeciesSummary :
Hu, Ms, Rat
Application Summary :
IP, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK