This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-Occludin antibody [EPR8208]
catalog :
ab167161
quantity :
10 µl, 100 µl
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
EPR8208
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - frozen section
citations: 18
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 1e
  • western blot; human; loading ...; fig 2a
Zhang Z, Zhang L, Zhang Q, Liu B, Li F, Xin Y, et al. HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1-/- Mice. Oxid Med Cell Longev. 2021;2021:6620873 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 7i
Kang L, Yu H, Yang X, Zhu Y, Bai X, Wang R, et al. Neutrophil extracellular traps released by neutrophils impair revascularization and vascular remodeling after stroke. Nat Commun. 2020;11:2488 pubmed publisher
  • western blot; mouse; loading ...; fig 2f, 4a
Shi H, Wang Q, Zheng M, Hao S, Lum J, Chen X, et al. Supplement of microbiota-accessible carbohydrates prevents neuroinflammation and cognitive decline by improving the gut microbiota-brain axis in diet-induced obese mice. J Neuroinflammation. 2020;17:77 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:4000; loading ...; fig 2c
Bendriem R, Singh S, Aleem A, Antonetti D, Ross M. Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex. elife. 2019;8: pubmed publisher
  • ELISA; mouse; 1:1000; fig 4
Löffler T, Flunkert S, Temmel M, Hutter Paier B. Decreased Plasma A? in Hyperlipidemic APPSL Transgenic Mice Is Associated with BBB Dysfunction. Front Neurosci. 2016;10:232 pubmed publisher
  • western blot; mouse; loading ...; fig 5k
Mathewson N, Jenq R, Mathew A, Koenigsknecht M, Hanash A, Toubai T, et al. Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host disease. Nat Immunol. 2016;17:505-513 pubmed publisher
  • western blot; rat; 1:1000; fig 7
Frankowski J, Demars K, Ahmad A, Hawkins K, Yang C, Leclerc J, et al. Detrimental role of the EP1 prostanoid receptor in blood-brain barrier damage following experimental ischemic stroke. Sci Rep. 2015;5:17956 pubmed publisher
  • immunohistochemistry; mouse; 1:50; fig 1d
  • western blot; mouse; 1:1000; fig 5f
Dong H, Chen Z, Wang C, Xiong Z, Zhao W, Jia C, et al. Rictor Regulates Spermatogenesis by Controlling Sertoli Cell Cytoskeletal Organization and Cell Polarity in the Mouse Testis. Endocrinology. 2015;156:4244-56 pubmed publisher
Cai L, Ge B, Xu S, Chen X, Yang H. Up-regulation of circARF3 reduces blood-brain barrier damage in rat subarachnoid hemorrhage model via miR-31-5p/MyD88/NF-κB axis. Aging (Albany NY). 2021;13:21345-21363 pubmed publisher
Wang S, Bai M, Xu K, Shao Y, Yang Z, Xiong X, et al. Effects of Coated Cysteamine on Oxidative Stress and Inflammation in Weaned Pigs. Animals (Basel). 2021;11: pubmed publisher
Tan Z, Chen L, Ren Y, Jiang X, Gao W. Neuroprotective effects of FK866 against traumatic brain injury: Involvement of p38/ERK pathway. Ann Clin Transl Neurol. 2020;7:742-756 pubmed publisher
Zhang K, Tu Y, Gao L, Meng M, Bai Y. Replacement of grains with soybean hulls ameliorates SARA-induced impairment of the colonic epithelium barrier function of goats. BMC Vet Res. 2018;14:376 pubmed publisher
Guo P, Zhang S, Zhang J, Dong J, Wu J, Tang S, et al. Effects of imipenem combined with low-dose cyclophosphamide on the intestinal barrier in septic rats. Exp Ther Med. 2018;16:1919-1927 pubmed publisher
Zhu H, Dai R, Zhou Y, Fu H, Meng Q. TLR2 Ligand Pam3CSK4 Regulates MMP-2/9 Expression by MAPK/NF-κB Signaling Pathways in Primary Brain Microvascular Endothelial Cells. Neurochem Res. 2018;43:1897-1904 pubmed publisher
Morgan S, Garwood C, Jennings L, Simpson J, Castelli L, Heath P, et al. Proteomic and cellular localisation studies suggest non-tight junction cytoplasmic and nuclear roles for occludin in astrocytes. Eur J Neurosci. 2018;47:1444-1456 pubmed publisher
Demars K, McCrea A, Siwarski D, Sanz B, Yang C, Candelario Jalil E. Protective Effects of L-902,688, a Prostanoid EP4 Receptor Agonist, against Acute Blood-Brain Barrier Damage in Experimental Ischemic Stroke. Front Neurosci. 2018;12:89 pubmed publisher
Cheng X, Wang X, Wan Y, Zhou Q, Zhu H, Wang Y. Myosin light chain kinase inhibitor ML7 improves vascular endothelial dysfunction via tight junction regulation in a rabbit model of atherosclerosis. Mol Med Rep. 2015;12:4109-4116 pubmed publisher
Elahy M, Jackaman C, Mamo J, Lam V, Dhaliwal S, Giles C, et al. Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment. Immun Ageing. 2015;12:2 pubmed publisher
product information
CatalogNumber :
ab167161
ItemName :
Anti-Occludin antibody [EPR8208]
Category :
Antibody
Host :
Rabbit
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
EPR8208
Size :
10 µl, 100 µl
SpeciesSummary :
Hu, Ms, Rat
Application Summary :
IP, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK