This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-Iba1 antibody [1022-5]
catalog :
ab15690
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1022-5
reactivity :
human, mouse, rat, dogs
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 31
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; rat; 1:1000; loading ...; fig 5e
Kim J, Ahn M, Choi Y, Chun J, Jung K, Tanaka A, et al. Osteopontin is a biomarker for early autoimmune uveoretinitis. Neural Regen Res. 2022;17:1604-1608 pubmed publisher
  • immunohistochemistry; rat; 1:100; loading ...; fig 2a
Xiao J, Cai T, Fang Y, Liu R, Flores J, Wang W, et al. Activation of GPR40 attenuates neuroinflammation and improves neurological function via PAK4/CREB/KDM6B pathway in an experimental GMH rat model. J Neuroinflammation. 2021;18:160 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 3g
Amal H, Gong G, Gjoneska E, Lewis S, Wishnok J, Tsai L, et al. S-nitrosylation of E3 ubiquitin-protein ligase RNF213 alters non-canonical Wnt/Ca+2 signaling in the P301S mouse model of tauopathy. Transl Psychiatry. 2019;9:44 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig st9
  • immunohistochemistry - paraffin section; dogs; 1:200; loading ...; fig st9
  • immunohistochemistry - paraffin section; rat; 1:200; loading ...; fig st9
Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
  • immunocytochemistry; human; 1:200; fig s3b
Sellgren C, Sheridan S, Gracias J, Xuan D, Fu T, Perlis R. Patient-specific models of microglia-mediated engulfment of synapses and neural progenitors. Mol Psychiatry. 2017;22:170-177 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 4
Singh V, Singh M, Gorantla S, Poluektova L, Maggirwar S. Smoothened Agonist Reduces Human Immunodeficiency Virus Type-1-Induced Blood-Brain Barrier Breakdown in Humanized Mice. Sci Rep. 2016;6:26876 pubmed publisher
  • western blot; rat; 1:500; loading ...; tbl 1
Fan J, Fan X, Li Y, Guo J, Xia D, Ding L, et al. Blunted inflammation mediated by NF-κB activation in hippocampus alleviates chronic normobaric hypoxia-induced anxiety-like behavior in rats. Brain Res Bull. 2016;122:54-61 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:5000; fig s3
Maeda S, Djukic B, Taneja P, Yu G, Lo I, Davis A, et al. Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice. EMBO Rep. 2016;17:530-51 pubmed publisher
  • western blot; mouse; 1:200
Rolón Reyes K, Kucheryavykh Y, Cubano L, Inyushin M, Skatchkov S, Eaton M, et al. Microglia Activate Migration of Glioma Cells through a Pyk2 Intracellular Pathway. PLoS ONE. 2015;10:e0131059 pubmed publisher
  • immunohistochemistry; rat
Kim S, Chung Y, Lee H, Chung S, Lee J, Sohn U, et al. Protective effects of phosphatidylcholine on oxaliplatin-induced neuropathy in rats. Life Sci. 2015;130:81-7 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:200
Maurya S, Mishra J, Abbas S, Bandyopadhyay S. Cypermethrin Stimulates GSK3β-Dependent Aβ and p-tau Proteins and Cognitive Loss in Young Rats: Reduced HB-EGF Signaling and Downstream Neuroinflammation as Critical Regulators. Mol Neurobiol. 2016;53:968-82 pubmed publisher
  • immunocytochemistry; rat; 1:200
Huang L, Zhu G, Deng Y, Jiang W, Fang M, Chen C, et al. Hypertonic saline alleviates cerebral edema by inhibiting microglia-derived TNF-? and IL-1?-induced Na-K-Cl Cotransporter up-regulation. J Neuroinflammation. 2014;11:102 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig s10a
Paez Gonzalez P, Asrican B, Rodriguez E, Kuo C. Identification of distinct ChAT? neurons and activity-dependent control of postnatal SVZ neurogenesis. Nat Neurosci. 2014;17:934-42 pubmed publisher
  • ELISA; mouse; 1:100
Tan M, Yu J, Jiang T, Zhu X, Guan H, Tan L. IL12/23 p40 inhibition ameliorates Alzheimer's disease-associated neuropathology and spatial memory in SAMP8 mice. J Alzheimers Dis. 2014;38:633-46 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:200
Savard A, Lavoie K, Brochu M, Grbic D, Lepage M, Gris D, et al. Involvement of neuronal IL-1? in acquired brain lesions in a rat model of neonatal encephalopathy. J Neuroinflammation. 2013;10:110 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200
Dilworth J, Krueger S, Dabjan M, Grills I, Torma J, Wilson G, et al. Pulsed low-dose irradiation of orthotopic glioblastoma multiforme (GBM) in a pre-clinical model: effects on vascularization and tumor control. Radiother Oncol. 2013;108:149-54 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:500
Harris N, Nogueira M, Verley D, Sutton R. Chondroitinase enhances cortical map plasticity and increases functionally active sprouting axons after brain injury. J Neurotrauma. 2013;30:1257-69 pubmed publisher
  • immunohistochemistry; rat; 1:200
Chio C, Chang C, Wang C, Cheong C, Chao C, Cheng B, et al. Etanercept attenuates traumatic brain injury in rats by reducing early microglial expression of tumor necrosis factor-?. BMC Neurosci. 2013;14:33 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:1000
Cao L, Li L, Lin D, Zuo Z. Isoflurane induces learning impairment that is mediated by interleukin 1? in rodents. PLoS ONE. 2012;7:e51431 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:200
Zhu X, Huang C, Li Q, Guo Q, Wang Y, He X, et al. Temporal distribution of p300/CBP immunoreactivity in the adult rat spinal dorsal horn following chronic constriction injury (CCI). Cell Mol Neurobiol. 2013;33:197-204 pubmed publisher
Cao H, Han X, Jia Y, Zhang B. Inhibition of long non-coding RNA HOXA11-AS against neuroinflammation in Parkinson's disease model via targeting miR-124-3p mediated FSTL1/NF-κB axis. Aging (Albany NY). 2021;13:11455-11469 pubmed publisher
Zheng B, Zhang S, Ying Y, Guo X, Li H, Xu L, et al. Administration of Dexmedetomidine inhibited NLRP3 inflammasome and microglial cell activities in hippocampus of traumatic brain injury rats. Biosci Rep. 2018;38: pubmed publisher
Reinert L, Lopušná K, Winther H, Sun C, Thomsen M, Nandakumar R, et al. Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS. Nat Commun. 2016;7:13348 pubmed publisher
Shi X, Chen Y, Liu H, Qu H. Therapeutic effects of paeonol on methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid-induced Parkinson's disease in mice. Mol Med Rep. 2016;14:2397-404 pubmed publisher
Liao K, Guo M, Niu F, Yang L, Callen S, Buch S. Cocaine-mediated induction of microglial activation involves the ER stress-TLR2 axis. J Neuroinflammation. 2016;13:33 pubmed publisher
Kim S, Lee H, Yun J, Ko J, Choi D, Oh J. Intravitreal TSG-6 suppresses laser-induced choroidal neovascularization by inhibiting CCR2+ monocyte recruitment. Sci Rep. 2015;5:11872 pubmed publisher
Savard A, Brochu M, Chevin M, Guiraut C, Grbic D, Sébire G. Neuronal self-injury mediated by IL-1β and MMP-9 in a cerebral palsy model of severe neonatal encephalopathy induced by immune activation plus hypoxia-ischemia. J Neuroinflammation. 2015;12:111 pubmed publisher
Buonora J, Mousseau M, Jacobowitz D, Lazarus R, Yarnell A, Olsen C, et al. Autoimmune Profiling Reveals Peroxiredoxin 6 as a Candidate Traumatic Brain Injury Biomarker. J Neurotrauma. 2015;32:1805-14 pubmed publisher
Yang S, Lin J, Chiu B, Hsu Y, Chang C, Chang C. Astragaloside improves outcomes of traumatic brain injury in rats by reducing microglia activation. Am J Chin Med. 2014;42:1357-70 pubmed publisher
Birngruber T, Ghosh A, Hochmeister S, Asslaber M, Kroath T, Pieber T, et al. Long-term implanted cOFM probe causes minimal tissue reaction in the brain. PLoS ONE. 2014;9:e90221 pubmed publisher
Yao Z, Zhang L, Huang L, Zhu H, Liu Y, Ma C, et al. Regional and cell-type specific distribution of HDAC2 in the adult mouse brain. Brain Struct Funct. 2013;218:563-73 pubmed publisher
product information
CatalogNumber :
ab15690
ItemName :
Anti-Iba1 antibody [1022-5]
Product Type :
Antibody
Host Species :
Mouse
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
1022-5
Size :
100 µg
SpeciesSummary :
Hu, Ms, Rat
Purity :
IgG fraction
Application Summary :
ICC/IF, IHC-P, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK