| Published Application/Species/Sample/Dilution | Reference |
|---|
- RNA immunoprecipitation; human; 1:500; loading ...; fig 7d
| Zhang H, Liu J, Zhou Y, Qu M, Wang Y, Guo K, et al. Neutrophil extracellular traps mediate m6A modification and regulates sepsis-associated acute lung injury by activating ferroptosis in alveolar epithelial cells. Int J Biol Sci. 2022;18:3337-3357 pubmed publisher |
- western blot; human; 1:500; loading ...
| Yang Z, Jiang X, Li D, Jiang X. HBXIP promotes gastric cancer via METTL3-mediated MYC mRNA m6A modification. Aging (Albany NY). 2020;12:24967-24982 pubmed publisher |
- other; mouse; loading ...; fig 2a
| Song T, Yang Y, Wei H, Xie X, Lu J, Zeng Q, et al. Zfp217 mediates m6A mRNA methylation to orchestrate transcriptional and post-transcriptional regulation to promote adipogenic differentiation. Nucleic Acids Res. 2019;: pubmed publisher |
- western blot; human; loading ...
| Vu L, Pickering B, Cheng Y, Zaccara S, Nguyen D, Minuesa G, et al. The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. Nat Med. 2017;23:1369-1376 pubmed publisher |
| Qiao Y, Sun Q, Chen X, He L, Wang D, Su R, et al. Nuclear m6A reader YTHDC1 promotes muscle stem cell activation/proliferation by regulating mRNA splicing and nuclear export. elife. 2023;12: pubmed publisher |
| Wang L, Wang S, Wu L, Li W, Bray W, Clark A, et al. PCIF1-mediated deposition of 5'-cap N6,2'-O-dimethyladenosine in ACE2 and TMPRSS2 mRNA regulates susceptibility to SARS-CoV-2 infection. Proc Natl Acad Sci U S A. 2023;120:e2210361120 pubmed publisher |
| Porman A, Roberts J, Duncan E, Chrupcala M, Levine A, Kennedy M, et al. A single N6-methyladenosine site regulates lncRNA HOTAIR function in breast cancer cells. PLoS Biol. 2022;20:e3001885 pubmed publisher |
| Wang A, Chen Y, Shi L, Li M, Li L, Wang S, et al. Tumor-suppressive MEG3 induces microRNA-493-5p expression to reduce arabinocytosine chemoresistance of acute myeloid leukemia cells by downregulating the METTL3/MYC axis. J Transl Med. 2022;20:288 pubmed publisher |
| Cui X, Nilsson K, Kajitani N, Schwartz S. Overexpression of m6A-factors METTL3, ALKBH5, and YTHDC1 alters HPV16 mRNA splicing. Virus Genes. 2022;58:98-112 pubmed publisher |
| Pereira Montecinos C, Toro Ascuy D, Ananías Sáez C, Gaete Argel A, Rojas Fuentes C, Riquelme Barrios S, et al. Epitranscriptomic regulation of HIV-1 full-length RNA packaging. Nucleic Acids Res. 2022;50:2302-2318 pubmed publisher |
| Sebastian DelaCruz M, Olazagoitia Garmendia A, Gonzalez Moro I, Santin I, Garcia Etxebarria K, Castellanos Rubio A. Implication of m6A mRNA Methylation in Susceptibility to Inflammatory Bowel Disease. Epigenomes. 2020;4: pubmed publisher |
| Léger A, Amaral P, Pandolfini L, Capitanchik C, Capraro F, Miano V, et al. RNA modifications detection by comparative Nanopore direct RNA sequencing. Nat Commun. 2021;12:7198 pubmed publisher |
| Xiao P, Li M, Zhou M, Zhao X, Wang C, Qiu J, et al. TTP protects against acute liver failure by regulating CCL2 and CCL5 through m6A RNA methylation. JCI Insight. 2021;6: pubmed publisher |
| Zhang Q, Kang Y, Wang S, Gonzalez G, Li W, Hui H, et al. HIV reprograms host m6Am RNA methylome by viral Vpr protein-mediated degradation of PCIF1. Nat Commun. 2021;12:5543 pubmed publisher |
| Wei G, Almeida M, Pintacuda G, Coker H, Bowness J, Ule J, et al. Acute depletion of METTL3 implicates N 6-methyladenosine in alternative intron/exon inclusion in the nascent transcriptome. Genome Res. 2021;31:1395-1408 pubmed publisher |
| Cotter K, Gallon J, Uebersax N, Rubin P, Meyer K, Piscuoglio S, et al. Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-Low Induction of Therapy Resistance. Mol Cancer Res. 2021;19:1398-1411 pubmed publisher |
| Zhang F, Yan Y, Cao X, Zhang J, Li Y, Guo C. Methylation of microRNA-338-5p by EED promotes METTL3-mediated translation of oncogene CDCP1 in gastric cancer. Aging (Albany NY). 2021;13:12224-12238 pubmed publisher |
| Cho S, Lee G, Pickering B, Jang C, Park J, He L, et al. mTORC1 promotes cell growth via m6A-dependent mRNA degradation. Mol Cell. 2021;81:2064-2075.e8 pubmed publisher |
| Ni X, Xie Q, Zhao J, Xu Y, Ji M, Hu W, et al. The hepatic microenvironment promotes lung adenocarcinoma cell proliferation, metastasis, and epithelial-mesenchymal transition via METTL3-mediated N6-methyladenosine modification of YAP1. Aging (Albany NY). 2021;13:4357-4369 pubmed publisher |
| Zhang H, Shi X, Huang T, Zhao X, Chen W, Gu N, et al. Dynamic landscape and evolution of m6A methylation in human. Nucleic Acids Res. 2020;48:6251-6264 pubmed publisher |
| Liu X, Zhou J, Mao Y, Ji Q, Qian S. Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 conjugates. Nat Chem Biol. 2019;15:865-871 pubmed publisher |
| Boulias K, Toczydłowska Socha D, Hawley B, Liberman N, Takashima K, Zaccara S, et al. Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome. Mol Cell. 2019;: pubmed publisher |
| Zhang X, Xu Y, Qian Z, Zheng W, Wu Q, Chen Y, et al. circRNA_104075 stimulates YAP-dependent tumorigenesis through the regulation of HNF4a and may serve as a diagnostic marker in hepatocellular carcinoma. Cell Death Dis. 2018;9:1091 pubmed publisher |
| Zhang Z, Wang M, Xie D, Huang Z, Zhang L, Yang Y, et al. METTL3-mediated N6-methyladenosine mRNA modification enhances long-term memory consolidation. Cell Res. 2018;28:1050-1061 pubmed publisher |
| Tang C, Klukovich R, Peng H, Wang Z, Yu T, Zhang Y, et al. ALKBH5-dependent m6A demethylation controls splicing and stability of long 3'-UTR mRNAs in male germ cells. Proc Natl Acad Sci U S A. 2018;115:E325-E333 pubmed publisher |
| Kan L, Grozhik A, Vedanayagam J, Patil D, Pang N, Lim K, et al. The m6A pathway facilitates sex determination in Drosophila. Nat Commun. 2017;8:15737 pubmed publisher |
| Sledź P, Jinek M. Structural insights into the molecular mechanism of the m(6)A writer complex. elife. 2016;5: pubmed publisher |
