This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-p53 (phospho S15) antibody
catalog :
ab1431
quantity :
50 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 4c
Zhou W, Xu Y, Zhang J, Zhang P, Yao Z, Yan Z, et al. MiRNA-363-3p/DUSP10/JNK axis mediates chemoresistance by enhancing DNA damage repair in diffuse large B-cell lymphoma. Leukemia. 2022;36:1861-1869 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 7b
Yeh C, Liu H, Lee M, Leu Y, Chiang W, Chang H, et al. Phytochemical‑rich herbal formula ATG‑125 protects against sucrose‑induced gastrocnemius muscle atrophy by rescuing Akt signaling and improving mitochondrial dysfunction in young adult mice. Mol Med Rep. 2022;25: pubmed publisher
  • immunocytochemistry; mouse; 1:100; loading ...; fig 5a
  • western blot; mouse; 1:500; loading ...; fig 3f
Zhang C, Xie Y, Chen H, Lv L, Yao J, Zhang M, et al. FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice. Aging (Albany NY). 2020;12:1272-1284 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 6c
Jin L, Lu J, Gao J. Silencing SUMO2 promotes protection against degradation and apoptosis of nucleus pulposus cells through p53 signaling pathway in intervertebral disc degeneration. Biosci Rep. 2018;38: pubmed publisher
  • western blot; human; 1:500; loading ...; fig 4b
Xie Y, Ma W, Meng J, Ren X. Knockdown of ZFPL1 results in increased autophagy and autophagy‑related cell death in NCI‑N87 and BGC‑823 human gastric carcinoma cell lines. Mol Med Rep. 2017;15:2633-2642 pubmed publisher
  • western blot; mouse; 1:5000; loading ...; fig 3a
Nakazawa H, Chang K, Shinozaki S, Yasukawa T, Ishimaru K, Yasuhara S, et al. iNOS as a Driver of Inflammation and Apoptosis in Mouse Skeletal Muscle after Burn Injury: Possible Involvement of Sirt1 S-Nitrosylation-Mediated Acetylation of p65 NF-κB and p53. PLoS ONE. 2017;12:e0170391 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig st3
  • western blot; human; 1:1000; loading ...; fig st3
Nassour J, Martien S, Martin N, Deruy E, Tomellini E, Malaquin N, et al. Defective DNA single-strand break repair is responsible for senescence and neoplastic escape of epithelial cells. Nat Commun. 2016;7:10399 pubmed publisher
  • western blot; human; loading ...; fig 5
Kramer H, Lai C, Patel H, Periyasamy M, Lin M, Feller S, et al. LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner. Nucleic Acids Res. 2016;44:582-94 pubmed publisher
Knapman F, Cohen E, Kulaga T, Lovell N, Lisowski L, McMullan S, et al. Direct optogenetic activation of upper airway muscles in an acute model of upper airway hypotonia mimicking sleep onset. Sleep. 2023;46: pubmed publisher
Jugel W, Tietze S, Daeg J, Appelhans D, Broghammer F, Aigner A, et al. Targeted Transposition of Minicircle DNA Using Single-Chain Antibody Conjugated Cyclodextrin-Modified Poly (Propylene Imine) Nanocarriers. Cancers (Basel). 2022;14: pubmed publisher
Tian M, Yang S, Yan X. Icariin reduces human colon carcinoma cell growth and metastasis by enhancing p53 activities. Braz J Med Biol Res. 2018;51:e7151 pubmed publisher
Guo J, Hao C, Wang C, Li L. Long noncoding RNA PVT1 modulates hepatocellular carcinoma cell proliferation and apoptosis by recruiting EZH2. Cancer Cell Int. 2018;18:98 pubmed publisher
Frisan T, Nagy N, Chioureas D, Terol M, Grasso F, Masucci M. A bacterial genotoxin causes virus reactivation and genomic instability in Epstein-Barr virus infected epithelial cells pointing to a role of co-infection in viral oncogenesis. Int J Cancer. 2019;144:98-109 pubmed publisher
Sang Q, Liu X, Wang L, Qi L, Sun W, Wang W, et al. CircSNCA downregulation by pramipexole treatment mediates cell apoptosis and autophagy in Parkinson's disease by targeting miR-7. Aging (Albany NY). 2018;10:1281-1293 pubmed publisher
Conde M, Michen S, Wiedemuth R, Klink B, Schrock E, Schackert G, et al. Chromosomal instability induced by increased BIRC5/Survivin levels affects tumorigenicity of glioma cells. BMC Cancer. 2017;17:889 pubmed publisher
Drayman N, Ben nun Shaul O, Butin Israeli V, Srivastava R, Rubinstein A, Mock C, et al. p53 elevation in human cells halt SV40 infection by inhibiting T-ag expression. Oncotarget. 2016;7:52643-52660 pubmed publisher
product information
CatalogNumber :
ab1431
ItemName :
Anti-p53 (phospho S15) antibody
Product Type :
Antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Conjugate :
Unconjugated
Size :
50 µg
SpeciesSummary :
Hu, Ms, Rat
Purity :
Protein A purified
Application Summary :
ICC/IF, IHC-Fr, IHC-P, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK