This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-E Cadherin antibody [HECD-1]
catalog :
ab1416
quantity :
250 µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
HECD-1
reactivity :
human, mouse, rat, domestic rabbit, rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 168
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000; loading ...; fig 4a
Li K, Wu R, Zhou M, Tong H, Luo K. Desmosomal proteins of DSC2 and PKP1 promote cancer cells survival and metastasis by increasing cluster formation in circulatory system. Sci Adv. 2021;7:eabg7265 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1b
Shelton W, Thomas S, Alexander H, Thomes C, Conway D, Dubash A. Desmoglein-2 harnesses a PDZ-GEF2/Rap1 signaling axis to control cell spreading and focal adhesions independent of cell-cell adhesion. Sci Rep. 2021;11:13295 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2b
Wan L, Wang Y, Zhang Z, Wang J, Niu M, Wu Y, et al. Elevated TEFM expression promotes growth and metastasis through activation of ROS/ERK signaling in hepatocellular carcinoma. Cell Death Dis. 2021;12:325 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 5h
Yokomizo R, Fujiki Y, Kishigami H, Kishi H, Kiyono T, Nakayama S, et al. Endometrial regeneration with endometrial epithelium: homologous orchestration with endometrial stroma as a feeder. Stem Cell Res Ther. 2021;12:130 pubmed publisher
  • immunocytochemistry; domestic rabbit; 1:50; loading ...; fig 5c
Wang Y, Gao G, Wu Y, Wang Y, Wu X, Zhou Q. S100A4 Silencing Facilitates Corneal Wound Healing After Alkali Burns by Promoting Autophagy via Blocking the PI3K/Akt/mTOR Signaling Pathway. Invest Ophthalmol Vis Sci. 2020;61:19 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 4h
Wu J, Song D, Li Z, Guo B, Xiao Y, Liu W, et al. Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis. Cell Res. 2020;30:794-809 pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; fig 6h
  • western blot; human; 1:1000; loading ...; fig 2f
Yang Y, Tai W, Lu N, Li T, Liu Y, Wu W, et al. lncRNA ZFAS1 promotes lung fibroblast-to-myofibroblast transition and ferroptosis via functioning as a ceRNA through miR-150-5p/SLC38A1 axis. Aging (Albany NY). 2020;12:9085-9102 pubmed publisher
  • immunocytochemistry; human; 1:200; loading ...; fig 4g
Schley G, Grampp S, Goppelt Struebe M. Inhibition of oxygen-sensing prolyl hydroxylases increases lipid accumulation in human primary tubular epithelial cells without inducing ER stress. Cell Tissue Res. 2020;381:125-140 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4g
Jin D, Guo J, Wu Y, Yang L, Wang X, Du J, et al. m6A demethylase ALKBH5 inhibits tumor growth and metastasis by reducing YTHDFs-mediated YAP expression and inhibiting miR-107/LATS2-mediated YAP activity in NSCLC. Mol Cancer. 2020;19:40 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3b
Ailiken G, Kitamura K, Hoshino T, Satoh M, Tanaka N, Minamoto T, et al. Post-transcriptional regulation of BRG1 by FIRΔexon2 in gastric cancer. Oncogenesis. 2020;9:26 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 7a, 7b
Feng Y, Ji D, Huang Y, Ji B, Zhang Y, Li J, et al. TGM3 functions as a tumor suppressor by repressing epithelial‑to‑mesenchymal transition and the PI3K/AKT signaling pathway in colorectal cancer. Oncol Rep. 2020;43:864-876 pubmed publisher
  • immunocytochemistry; rat; 1:1000; loading ...; fig s1b
Hou K, Li G, Zhao J, Xu B, Zhang Y, Yu J, et al. Bone mesenchymal stem cell-derived exosomal microRNA-29b-3p prevents hypoxic-ischemic injury in rat brain by activating the PTEN-mediated Akt signaling pathway. J Neuroinflammation. 2020;17:46 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 1s1c
Kasendra M, Luc R, Yin J, Manatakis D, Kulkarni G, Lucchesi C, et al. Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model. elife. 2020;9: pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1b, 7a
  • western blot; human; loading ...; fig 1a
Du X, Zhang Z, Zheng X, Zhang H, Dong D, Zhang Z, et al. An electrochemical biosensor for the detection of epithelial-mesenchymal transition. Nat Commun. 2020;11:192 pubmed publisher
  • immunohistochemistry; human; 1:100; loading ...
Belote R, Simon S. Ca2+ transients in melanocyte dendrites and dendritic spine-like structures evoked by cell-to-cell signaling. J Cell Biol. 2020;219: pubmed publisher
  • immunohistochemistry - frozen section; human; 1:500; loading ...; fig 1a
Foster A, El Chami C, O Neill C, Watson R. Osmolyte transporter expression is reduced in photoaged human skin: Implications for skin hydration in aging. Aging Cell. 2020;19:e13058 pubmed publisher
  • western blot; human; loading ...; fig 2c
He W, Tang J, Li W, Li Y, Mei Y, He L, et al. Mutual regulation of JAG2 and PRAF2 promotes migration and invasion of colorectal cancer cells uncoupled from epithelial-mesenchymal transition. Cancer Cell Int. 2019;19:160 pubmed publisher
  • western blot; human; loading ...; fig 1a
Hu J, Guan W, Yan L, Ye Z, Wu L, Xu H. Cancer Stem Cell Marker Endoglin (CD105) Induces Epithelial Mesenchymal Transition (EMT) but Not Metastasis in Clear Cell Renal Cell Carcinoma. Stem Cells Int. 2019;2019:9060152 pubmed publisher
  • immunocytochemistry; human; 5 ug/ml; loading ...; fig 6a
  • western blot; human; 1:50; loading ...; fig 3b
Tang L, Wen J, Wen P, Li X, Gong M, Li Q. Long non-coding RNA LINC01314 represses cell migration, invasion, and angiogenesis in gastric cancer via the Wnt/β-catenin signaling pathway by down-regulating KLK4. Cancer Cell Int. 2019;19:94 pubmed publisher
  • western blot; human; loading ...; fig 3a, 3c
Gao X, Liu X, Lu Y, Wang Y, Cao W, Liu X, et al. PIM1 is responsible for IL-6-induced breast cancer cell EMT and stemness via c-myc activation. Breast Cancer. 2019;: pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 3e, 3f
Li Y, Lu Y, Chen Y. Long non-coding RNA SNHG16 affects cell proliferation and predicts a poor prognosis in patients with colorectal cancer via sponging miR-200a-3p. Biosci Rep. 2019;39: pubmed publisher
  • western blot; human; 1:3000; fig 2b
Zhang C, Wang Y. Metformin attenuates cells stemness and epithelial‑mesenchymal transition in colorectal cancer cells by inhibiting the Wnt3a/β‑catenin pathway. Mol Med Rep. 2019;19:1203-1209 pubmed publisher
  • western blot; human; loading ...; fig 3a
Tang Z, Ding Y, Shen Q, Zhang C, Li J, Nazar M, et al. KIAA1199 promotes invasion and migration in non-small-cell lung cancer (NSCLC) via PI3K-Akt mediated EMT. J Mol Med (Berl). 2019;97:127-140 pubmed publisher
  • western blot; human; loading ...; fig 3c
Zheng C, Wang J, Lin M, Zhang P, Liu L, Lin J, et al. CDK5RAP3 suppresses Wnt/β-catenin signaling by inhibiting AKT phosphorylation in gastric cancer. J Exp Clin Cancer Res. 2018;37:59 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 1c
Hsieh W, Ramadesikan S, FEKETE D, Aguilar R. Kidney-differentiated cells derived from Lowe Syndrome patient's iPSCs show ciliogenesis defects and Six2 retention at the Golgi complex. PLoS ONE. 2018;13:e0192635 pubmed publisher
  • western blot; human; 1:100; loading ...; fig 1b
Sallais J, Alahari S, Tagliaferro A, Bhattacharjee J, Post M, Caniggia I. Factor inhibiting HIF1-A novel target of SUMOylation in the human placenta. Oncotarget. 2017;8:114002-114018 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1b
You S, Guan Y, Li W. Epithelial?mesenchymal transition in colorectal carcinoma cells is mediated by DEK/IMP3. Mol Med Rep. 2017;: pubmed publisher
  • immunohistochemistry; human; loading ...; fig 6i
  • western blot; human; loading ...; fig 5d
Luo W, Tan P, Rodriguez M, He L, Tan K, Zeng L, et al. Leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial-mesenchymal transition. J Biol Chem. 2017;292:15525-15537 pubmed publisher
  • flow cytometry; human; loading ...; fig s4b
Solis N, Swidergall M, Bruno V, Gaffen S, Filler S. The Aryl Hydrocarbon Receptor Governs Epithelial Cell Invasion during Oropharyngeal Candidiasis. MBio. 2017;8: pubmed publisher
  • western blot; human; loading ...; fig 2e
Li K, Mo C, Gong D, Chen Y, Huang Z, Li Y, et al. DDX17 nucleocytoplasmic shuttling promotes acquired gefitinib resistance in non-small cell lung cancer cells via activation of β-catenin. Cancer Lett. 2017;400:194-202 pubmed publisher
  • immunocytochemistry; human; 1:50; loading ...; fig s7c
Gamal W, Treskes P, Samuel K, Sullivan G, Siller R, Srsen V, et al. Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver. Sci Rep. 2017;7:37541 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 1f
Griggs L, Hassan N, Malik R, Griffin B, Martinez B, Elmore L, et al. Fibronectin fibrils regulate TGF-?1-induced Epithelial-Mesenchymal Transition. Matrix Biol. 2017;60-61:157-175 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 7a
Price A, Huang E, Sebastiano V, Dunn A. A semi-interpenetrating network of polyacrylamide and recombinant basement membrane allows pluripotent cell culture in a soft, ligand-rich microenvironment. Biomaterials. 2017;121:179-192 pubmed publisher
  • western blot; human; loading ...; fig 1h
Han X, Fang Z, Wang H, Jiao R, Zhou J, Fang N. CUL4A functions as an oncogene in ovarian cancer and is directly regulated by miR-494. Biochem Biophys Res Commun. 2016;480:675-681 pubmed publisher
  • western blot; human; 1:50; loading ...; fig 4a
Tang Z, Li J, Shen Q, Feng J, Liu H, Wang W, et al. Contribution of upregulated dipeptidyl peptidase 9 (DPP9) in promoting tumoregenicity, metastasis and the prediction of poor prognosis in non-small cell lung cancer (NSCLC). Int J Cancer. 2017;140:1620-1632 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1d
  • immunohistochemistry; human; fig 1h
  • western blot; human; loading ...; fig 1e
Gao C, Su Y, Koeman J, Haak E, Dykema K, Essenberg C, et al. Chromosome instability drives phenotypic switching to metastasis. Proc Natl Acad Sci U S A. 2016;113:14793-14798 pubmed publisher
  • western blot; human; fig 3
Li C, Li Q, Cai Y, He Y, Lan X, Wang W, et al. Overexpression of angiopoietin 2 promotes the formation of oral squamous cell carcinoma by increasing epithelial-mesenchymal transition-induced angiogenesis. Cancer Gene Ther. 2016;23:295-302 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 1
He Y, Ou Z, Chen X, Zu X, Liu L, Li Y, et al. LPS/TLR4 Signaling Enhances TGF-β Response Through Downregulating BAMBI During Prostatic Hyperplasia. Sci Rep. 2016;6:27051 pubmed publisher
  • western blot; human; fig 3D
Hong L, Pan F, Jiang H, Zhang L, Liu Y, Cai C, et al. miR-125b inhibited epithelial-mesenchymal transition of triple-negative breast cancer by targeting MAP2K7. Onco Targets Ther. 2016;9:2639-48 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:50; fig 8
  • immunocytochemistry; human; 1:50; fig 6
  • western blot; human; 1:50; fig 6
Zhao N, Sun H, Sun B, Zhu D, Zhao X, Wang Y, et al. miR-27a-3p suppresses tumor metastasis and VM by down-regulating VE-cadherin expression and inhibiting EMT: an essential role for Twist-1 in HCC. Sci Rep. 2016;6:23091 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 9
Rodrigues Pinto R, Berry A, Piper Hanley K, Hanley N, Richardson S, Hoyland J. Spatiotemporal analysis of putative notochordal cell markers reveals CD24 and keratins 8, 18, and 19 as notochord-specific markers during early human intervertebral disc development. J Orthop Res. 2016;34:1327-40 pubmed publisher
  • immunohistochemistry - frozen section; human; fig 1
Stahley S, Warren M, Feldman R, Swerlick R, Mattheyses A, Kowalczyk A. Super-Resolution Microscopy Reveals Altered Desmosomal Protein Organization in Tissue from Patients with Pemphigus Vulgaris. J Invest Dermatol. 2016;136:59-66 pubmed publisher
  • immunocytochemistry; human; fig s7a
Sun Y, Zhu D, Chen F, Qian M, Wei H, Chen W, et al. SFRP2 augments WNT16B signaling to promote therapeutic resistance in the damaged tumor microenvironment. Oncogene. 2016;35:4321-34 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 7
Kumar N, Richter J, Cutts J, Bush K, Trujillo C, Nigam S, et al. Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells. elife. 2015;4: pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1c
Abou Kheir W, Eid A, El Merahbi R, Assaf R, Daoud G. A Unique Expression of Keratin 14 in a Subset of Trophoblast Cells. PLoS ONE. 2015;10:e0139939 pubmed publisher
  • immunoprecipitation; human; fig 4b
  • western blot; human; fig 4d
Brusgard J, Choe M, Chumsri S, Renoud K, MacKerell A, Sudol M, et al. RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells. Oncotarget. 2015;6:28132-50 pubmed publisher
  • immunocytochemistry; rhesus macaque; 1:500; fig 2
  • western blot; rhesus macaque; 1:500; fig 8
Kumar P, Thirkill T, Ji J, Monte L, Douglas G. Differential Effects of Sodium Butyrate and Lithium Chloride on Rhesus Monkey Trophoblast Differentiation. PLoS ONE. 2015;10:e0135089 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:300; fig 4
  • western blot; human; 1:600; fig 7
Nishioka M, Venkatesan N, Dessalle K, Mogas A, Kyoh S, Lin T, et al. Fibroblast-epithelial cell interactions drive epithelial-mesenchymal transition differently in cells from normal and COPD patients. Respir Res. 2015;16:72 pubmed publisher
  • immunocytochemistry; human
Saias L, Gomes A, Cazales M, Ducommun B, Lobjois V. Cell-Cell Adhesion and Cytoskeleton Tension Oppose Each Other in Regulating Tumor Cell Aggregation. Cancer Res. 2015;75:2426-33 pubmed publisher
  • western blot; human; loading ...; fig 2e
Chen X, Liu X, Lang H, Zhang S, Luo Y, Zhang J. S100 calcium-binding protein A6 promotes epithelial-mesenchymal transition through β-catenin in pancreatic cancer cell line. PLoS ONE. 2015;10:e0121319 pubmed publisher
  • western blot; human; 1:1000; fig 3
Gu J, Xu F, Zhao G, Lu C, Lin Z, Ding J, et al. Capn4 promotes non-small cell lung cancer progression via upregulation of matrix metalloproteinase 2. Med Oncol. 2015;32:51 pubmed publisher
  • immunocytochemistry; human; 1:100
Fan C, Jiang G, Zhang X, Miao Y, Lin X, Luan L, et al. Zbed3 contributes to malignant phenotype of lung cancer via regulating β-catenin and P120-catenin 1. Mol Carcinog. 2015;54 Suppl 1:E138-47 pubmed publisher
  • immunocytochemistry; human; 1:50
Dolega M, Wagh J, Gerbaud S, Kermarrec F, Alcaraz J, Martin D, et al. Facile bench-top fabrication of enclosed circular microchannels provides 3D confined structure for growth of prostate epithelial cells. PLoS ONE. 2014;9:e99416 pubmed publisher
  • western blot; human
Weng W, Yin J, Zhang Y, Qiu J, Wang X. Metastasis-associated protein 1 promotes tumor invasion by downregulation of E-cadherin. Int J Oncol. 2014;44:812-8 pubmed publisher
  • immunocytochemistry; human
Chen J, Erikson D, Piltonen T, Meyer M, Barragan F, McIntire R, et al. Coculturing human endometrial epithelial cells and stromal fibroblasts alters cell-specific gene expression and cytokine production. Fertil Steril. 2013;100:1132-43 pubmed publisher
  • flow cytometry; human; 1:400
  • immunocytochemistry; human; 1:400
  • western blot; human
Sangar F, Schreurs A, Umana Diaz C, Claperon A, Desbois Mouthon C, Calmel C, et al. Involvement of small ArfGAP1 (SMAP1), a novel Arf6-specific GTPase-activating protein, in microsatellite instability oncogenesis. Oncogene. 2014;33:2758-67 pubmed publisher
  • immunocytochemistry; human; 1:500; fig s2
Garcia Murillas I, Sharpe R, Pearson A, Campbell J, Natrajan R, Ashworth A, et al. An siRNA screen identifies the GNAS locus as a driver in 20q amplified breast cancer. Oncogene. 2014;33:2478-86 pubmed publisher
Law R, Kiepas A, Desta H, Perez Ipi xf1 a E, Parlani M, Lee S, et al. Cytokinesis machinery promotes cell dissociation from collectively migrating strands in confinement. Sci Adv. 2023;9:eabq6480 pubmed publisher
Harmon R, Devany J, Gardel M. Dia1 coordinates differentiation and cell sorting in a stratified epithelium. J Cell Biol. 2022;221: pubmed publisher
Rauner G, Jin D, Miller D, Gierahn T, Li C, Sokol E, et al. Breast tissue regeneration is driven by cell-matrix interactions coordinating multi-lineage stem cell differentiation through DDR1. Nat Commun. 2021;12:7116 pubmed publisher
Kharin L, Bychkov I, Karnaukhov N, Voloshin M, Fazliyeva R, Deneka A, et al. Prognostic role and biologic features of Musashi-2 expression in colon polyps and during colorectal cancer progression. PLoS ONE. 2021;16:e0252132 pubmed publisher
Howden J, Michael M, Hight Warburton W, Parsons M. α2β1 integrins spatially restrict Cdc42 activity to stabilise adherens junctions. BMC Biol. 2021;19:130 pubmed publisher
Zhou B, Xiang J, Jin M, Zheng X, Li G, Yan S. High vimentin expression with E-cadherin expression loss predicts a poor prognosis after resection of grade 1 and 2 pancreatic neuroendocrine tumors. BMC Cancer. 2021;21:334 pubmed publisher
Xiao Z, Li J, Jin Q, Liu D. Long non-coding RNA OIP5-AS1 contributes to cisplatin resistance of oral squamous cell carcinoma through the miR-27b-3p/TRIM14 axis. Exp Ther Med. 2021;21:408 pubmed publisher
Zhang H, Zhang K, Xu Z, Chen Z, Wang Q, Wang C, et al. MicroRNA-545 suppresses progression of ovarian cancer through mediating PLK1 expression by a direct binding and an indirect regulation involving KDM4B-mediated demethylation. BMC Cancer. 2021;21:163 pubmed publisher
Zhang B, Cui H, Sun Y, Wang X, Jia Q, Li J, et al. Up-regulation of miR-204 inhibits proliferation, invasion and apoptosis of gallbladder cancer cells by targeting Notch2. Aging (Albany NY). 2021;13:2941-2958 pubmed publisher
Yang X, Meng L, Zhong Y, Hu F, Wang L, Wang M. The long intergenic noncoding RNA GAS5 reduces cisplatin-resistance in non-small cell lung cancer through the miR-217/LHPP axis. Aging (Albany NY). 2021;13:2864-2884 pubmed publisher
Jiang H, Li X, Wang W, Dong H. Long non-coding RNA SNHG3 promotes breast cancer cell proliferation and metastasis by binding to microRNA-154-3p and activating the notch signaling pathway. BMC Cancer. 2020;20:838 pubmed publisher
Kutys M, Polacheck W, Welch M, Gagnon K, Koorman T, Kim S, et al. Uncovering mutation-specific morphogenic phenotypes and paracrine-mediated vessel dysfunction in a biomimetic vascularized mammary duct platform. Nat Commun. 2020;11:3377 pubmed publisher
Gao G, Yang M, Wang F, Dang G, Zhang X, Zhao J, et al. Coagulation factor 2 thrombin receptor promotes malignancy in glioma under SOX2 regulation. Aging (Albany NY). 2020;12:10594-10613 pubmed publisher
Zhang Y, Le T, Grabau R, Mohseni Z, Kim H, Natale D, et al. TMEM16F phospholipid scramblase mediates trophoblast fusion and placental development. Sci Adv. 2020;6:eaba0310 pubmed publisher
Sun Y, Cao B, Zhou J. Roles of DANCR/microRNA-518a-3p/MDMA ceRNA network in the growth and malignant behaviors of colon cancer cells. BMC Cancer. 2020;20:434 pubmed publisher
Liang L, Wu J, Luo J, Wang L, Chen Z, Han C, et al. Oxymatrine reverses 5-fluorouracil resistance by inhibition of colon cancer cell epithelial-mesenchymal transition and NF-κB signaling in vitro. Oncol Lett. 2020;19:519-526 pubmed publisher
Cavanaugh K, Staddon M, Munro E, Banerjee S, Gardel M. RhoA Mediates Epithelial Cell Shape Changes via Mechanosensitive Endocytosis. Dev Cell. 2019;: pubmed publisher
Gu N, Wang X, DI Z, Xiong J, Ma Y, Yan Y, et al. Silencing lncRNA FOXD2-AS1 inhibits proliferation, migration, invasion and drug resistance of drug-resistant glioma cells and promotes their apoptosis via microRNA-98-5p/CPEB4 axis. Aging (Albany NY). 2019;11:10266-10283 pubmed publisher
Chen J, Liu J, Lei Y, Liu M. The anti-inflammation, anti-oxidative and anti-fibrosis properties of swertiamarin in cigarette smoke exposure-induced prostate dysfunction in rats. Aging (Albany NY). 2019;11:10409-10421 pubmed publisher
Long R, Liu Z, Li J, Yu H. COL6A6 interacted with P4HA3 to suppress the growth and metastasis of pituitary adenoma via blocking PI3K-Akt pathway. Aging (Albany NY). 2019;11:8845-8859 pubmed publisher
Haley J, Ruiz C, Montal E, Wang D, Haley J, Girnun G. Decoupling of Nrf2 Expression Promotes Mesenchymal State Maintenance in Non-Small Cell Lung Cancer. Cancers (Basel). 2019;11: pubmed publisher
Zhang Y, Sun L, Gao X, Guo A, Diao Y, Zhao Y. RNF43 ubiquitinates and degrades phosphorylated E-cadherin by c-Src to facilitate epithelial-mesenchymal transition in lung adenocarcinoma. BMC Cancer. 2019;19:670 pubmed publisher
Chen F, Liu M, Yu Y, Sun Y, Li J, Hu W, et al. LINC00958 regulated miR-627-5p/YBX2 axis to facilitate cell proliferation and migration in oral squamous cell carcinoma. Cancer Biol Ther. 2019;:1-11 pubmed publisher
Mobasseri S, Zijl S, Salameti V, Walko G, Stannard A, Garcia Manyes S, et al. Patterning of human epidermal stem cells on undulating elastomer substrates reflects differences in cell stiffness. Acta Biomater. 2019;: pubmed publisher
Liu B, Xu L, Dai E, Tian J, Li J. Anti-tumoral potential of MDA19 in human osteosarcoma via suppressing PI3K/Akt/mTOR signaling pathway. Biosci Rep. 2018;38: pubmed publisher
Liu J, Huang C, Peng C, Xu F, Li Y, Yutaka Y, et al. Stromal fibroblast activation protein alpha promotes gastric cancer progression via epithelial-mesenchymal transition through Wnt/ β-catenin pathway. BMC Cancer. 2018;18:1099 pubmed publisher
Al Khalaf H, Al Harbi B, Al Sayed A, Arafah M, Tulbah A, Jarman A, et al. Interleukin-8 Activates Breast Cancer-Associated Adipocytes and Promotes Their Angiogenesis- and Tumorigenesis-Promoting Effects. Mol Cell Biol. 2019;39: pubmed publisher
He Z, Xu Q, Wang X, Wang J, Mu X, Cai Y, et al. RPLP1 promotes tumor metastasis and is associated with a poor prognosis in triple-negative breast cancer patients. Cancer Cell Int. 2018;18:170 pubmed publisher
Acharya B, Nestor Bergmann A, Liang X, Gupta S, Duszyc K, Gauquelin E, et al. A Mechanosensitive RhoA Pathway that Protects Epithelia against Acute Tensile Stress. Dev Cell. 2018;47:439-452.e6 pubmed publisher
Liu Z, Chen M, Xie L, Liu T, Zou Z, Li Y, et al. CLCA4 inhibits cell proliferation and invasion of hepatocellular carcinoma by suppressing epithelial-mesenchymal transition via PI3K/AKT signaling. Aging (Albany NY). 2018;10:2570-2584 pubmed publisher
Libby A, Joy D, So P, Mandegar M, Muncie J, Mendoza Camacho F, et al. Spatiotemporal mosaic self-patterning of pluripotent stem cells using CRISPR interference. elife. 2018;7: pubmed publisher
Wang H, Ke J, Guo Q, Barnabo Nampoukime K, Yang P, Ma K. Long non-coding RNA CRNDE promotes the proliferation, migration and invasion of hepatocellular carcinoma cells through miR-217/MAPK1 axis. J Cell Mol Med. 2018;22:5862-5876 pubmed publisher
Fang L, Wu S, Zhu X, Cai J, Wu J, He Z, et al. MYEOV functions as an amplified competing endogenous RNA in promoting metastasis by activating TGF-β pathway in NSCLC. Oncogene. 2019;38:896-912 pubmed publisher
Shafraz O, Rübsam M, Stahley S, Caldara A, Kowalczyk A, Niessen C, et al. E-cadherin binds to desmoglein to facilitate desmosome assembly. elife. 2018;7: pubmed publisher
Razali R, Nik Ahmad Eid N, Jayaraman T, Amir Hassan M, Azlan N, Ismail N, et al. The potential of Olea europaea extracts to prevent TGF?1-induced epithelial to mesenchymal transition in human nasal respiratory epithelial cells. BMC Complement Altern Med. 2018;18:197 pubmed publisher
Ottaviani S, Stebbing J, Frampton A, Zagorac S, Krell J, de Giorgio A, et al. TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression. Nat Commun. 2018;9:1845 pubmed publisher
Jiang X, Huang Y, Liang X, Jiang F, He Y, Li T, et al. Metastatic prostate cancer-associated P62 inhibits autophagy flux and promotes epithelial to mesenchymal transition by sustaining the level of HDAC6. Prostate. 2018;78:426-434 pubmed publisher
Kaplan N, Ventrella R, Peng H, Pal Ghosh S, Arvanitis C, Rappoport J, et al. EphA2/Ephrin-A1 Mediate Corneal Epithelial Cell Compartmentalization via ADAM10 Regulation of EGFR Signaling. Invest Ophthalmol Vis Sci. 2018;59:393-406 pubmed publisher
Chen Y, Lu J, Xia L, Xue D, Yu X, Shen D, et al. Testicular orphan receptor 4 promotes tumor progression and implies poor survival through AKT3 regulation in seminoma. Cancer Sci. 2018;109:384-394 pubmed publisher
Rhys A, Monteiro P, Smith C, Vaghela M, Arnandis T, Kato T, et al. Loss of E-cadherin provides tolerance to centrosome amplification in epithelial cancer cells. J Cell Biol. 2018;217:195-209 pubmed publisher
Ortega F, Rengarajan M, Chavez N, Radhakrishnan P, Gloerich M, Bianchini J, et al. Adhesion to the host cell surface is sufficient to mediate Listeria monocytogenes entry into epithelial cells. Mol Biol Cell. 2017;28:2945-2957 pubmed publisher
Wood M, Ishiyama N, Singaram I, Chung C, Flozak A, Yemelyanov A, et al. α-Catenin homodimers are recruited to phosphoinositide-activated membranes to promote adhesion. J Cell Biol. 2017;216:3767-3783 pubmed publisher
Sommerova L, Ondrousková E, Vojtesek B, Hrstka R. Suppression of AGR2 in a TGF-β-induced Smad regulatory pathway mediates epithelial-mesenchymal transition. BMC Cancer. 2017;17:546 pubmed publisher
Wang J, Li Z, Li X, Han Z, Zhang L, Liu Z. Effects of microRNA-136 on melanoma cell proliferation, apoptosis, and epithelial-mesenchymal transition by targetting PMEL through the Wnt signaling pathway. Biosci Rep. 2017;37: pubmed publisher
Pallett L, Davies J, Colbeck E, Robertson F, Hansi N, Easom N, et al. IL-2high tissue-resident T cells in the human liver: Sentinels for hepatotropic infection. J Exp Med. 2017;214:1567-1580 pubmed publisher
Yuan Z, Chen D, Chen X, Yang H, Wei Y. Overexpression of trefoil factor 3 (TFF3) contributes to the malignant progression in cervical cancer cells. Cancer Cell Int. 2017;17:7 pubmed publisher
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product information
CatalogNumber :
ab1416
ItemName :
Anti-E Cadherin antibody [HECD-1]
Product Type :
Primary Antibodies
Host Species :
Mouse
Clonality :
Monoclonal
Conjugate :
Not Conjugated
Antigen Modification :
No Modifications
Clone Name :
HECD-1
Size :
250 µl
SpeciesSummary :
Hu, Rat
Uses :
Flow Cyt, ICC, ICC/IF, IHC-Fr, IHC-P, IP, WB
Size Note :
Other sizes available: 500 µl
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK