This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-Osteocalcin antibody [OC4-30]
catalog :
ab13418
quantity :
50 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
OC4-30
reactivity :
human, mouse, rat, dogs, bovine, domestic rabbit
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 43
Published Application/Species/Sample/DilutionReference
  • western blot; domestic rabbit; 1:1000; fig 10
Peng K, Hsieh M, Lin C, Chen C, Lee M, Huang Y, et al. Treatment of critically sized femoral defects with recombinant BMP-2 delivered by a modified mPEG-PLGA biodegradable thermosensitive hydrogel. BMC Musculoskelet Disord. 2016;17:286 pubmed publisher
  • immunohistochemistry - paraffin section; domestic rabbit; fig 6
Zhang J, Wang H, Shi J, Wang Y, Lai K, Yang X, et al. Combination of simvastatin, calcium silicate/gypsum, and gelatin and bone regeneration in rabbit calvarial defects. Sci Rep. 2016;6:23422 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 2b, c
Li S, Zou D, Li C, Meng H, Sui W, Feng S, et al. Targeting stem cell niche can protect hematopoietic stem cells from chemotherapy and G-CSF treatment. Stem Cell Res Ther. 2015;6:175 pubmed publisher
  • immunohistochemistry - paraffin section; rat; loading ...; fig 5
  • western blot; rat; loading ...; fig 4
Huang J, Liu L, Feng M, An S, Zhou M, Li Z, et al. Effect of CoClâ‚‚ on fracture repair in a rat model of bone fracture. Mol Med Rep. 2015;12:5951-6 pubmed publisher
  • immunohistochemistry; mouse
Lai G, Shalumon K, Chen J. Response of human mesenchymal stem cells to intrafibrillar nanohydroxyapatite content and extrafibrillar nanohydroxyapatite in biomimetic chitosan/silk fibroin/nanohydroxyapatite nanofibrous membrane scaffolds. Int J Nanomedicine. 2015;10:567-84 pubmed publisher
  • immunocytochemistry; domestic rabbit; 1:300
Zhang J, Wang J. Kartogenin induces cartilage-like tissue formation in tendon-bone junction. Bone Res. 2014;2: pubmed
  • western blot; rat; 1:400
Lu H, Lian L, Shi D, Zhao H, Dai Y. Hepcidin promotes osteogenic differentiation through the bone morphogenetic protein 2/small mothers against decapentaplegic and mitogen-activated protein kinase/P38 signaling pathways in mesenchymal stem cells. Mol Med Rep. 2015;11:143-50 pubmed publisher
  • western blot; rat; 1:1000
Wang Y, Li J, Song W, Yu J. Mineral trioxide aggregate upregulates odonto/osteogenic capacity of bone marrow stromal cells from craniofacial bones via JNK and ERK MAPK signalling pathways. Cell Prolif. 2014;47:241-8 pubmed publisher
  • immunohistochemistry - paraffin section; domestic rabbit; 10 ug/ml
  • immunocytochemistry; domestic rabbit; 1:200
Nguyen T, Lee B. A combination of biphasic calcium phosphate scaffold with hyaluronic acid-gelatin hydrogel as a new tool for bone regeneration. Tissue Eng Part A. 2014;20:1993-2004 pubmed publisher
  • immunohistochemistry; human
Dweck M, Jenkins W, Vesey A, Pringle M, Chin C, Malley T, et al. 18F-sodium fluoride uptake is a marker of active calcification and disease progression in patients with aortic stenosis. Circ Cardiovasc Imaging. 2014;7:371-8 pubmed publisher
  • western blot; human
Dai J, Li Y, Zhou H, Chen J, Chen M, Xiao Z. Genistein promotion of osteogenic differentiation through BMP2/SMAD5/RUNX2 signaling. Int J Biol Sci. 2013;9:1089-98 pubmed publisher
  • immunohistochemistry - frozen section; human
Paino F, La Noce M, Tirino V, Naddeo P, Desiderio V, Pirozzi G, et al. Histone deacetylase inhibition with valproic acid downregulates osteocalcin gene expression in human dental pulp stem cells and osteoblasts: evidence for HDAC2 involvement. Stem Cells. 2014;32:279-89 pubmed publisher
  • immunohistochemistry - paraffin section; human
Chen J, Tsai M, Liao H. Incorporation of biphasic calcium phosphate microparticles in injectable thermoresponsive hydrogel modulates bone cell proliferation and differentiation. Colloids Surf B Biointerfaces. 2013;110:120-9 pubmed publisher
  • immunocytochemistry; human
Silva A, Paula A, Martins T, Goes A, Pereria M. Synergistic effect between bioactive glass foam and a perfusion bioreactor on osteogenic differentiation of human adipose stem cells. J Biomed Mater Res A. 2014;102:818-27 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:200
Zhang J, Wang J. Human tendon stem cells better maintain their stemness in hypoxic culture conditions. PLoS ONE. 2013;8:e61424 pubmed publisher
  • immunohistochemistry; human; 1:100
  • western blot; human; 1:1000
Wang L, Yan M, Wang Y, Lei G, Yu Y, Zhao C, et al. Proliferation and osteo/odontoblastic differentiation of stem cells from dental apical papilla in mineralization-inducing medium containing additional KH(2)PO(4). Cell Prolif. 2013;46:214-22 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100
Li S, Zhai Q, Zou D, Meng H, Xie Z, Li C, et al. A pivotal role of bone remodeling in granulocyte colony stimulating factor induced hematopoietic stem/progenitor cells mobilization. J Cell Physiol. 2013;228:1002-9 pubmed publisher
Ji H, Cui X, Yang Y, Zhou X. CircRNA hsa_circ_0006215 promotes osteogenic differentiation of BMSCs and enhances osteogenesis-angiogenesis coupling by competitively binding to miR-942-5p and regulating RUNX2 and VEGF. Aging (Albany NY). 2021;13:10275-10288 pubmed publisher
Chan C, Gulati G, Sinha R, Tompkins J, Lopez M, Carter A, et al. Identification of the Human Skeletal Stem Cell. Cell. 2018;175:43-56.e21 pubmed publisher
Lim R, Li L, Chew N, Yong E. The prenylflavonoid Icaritin enhances osteoblast proliferation and function by signal transducer and activator of transcription factor 3 (STAT-3) regulation of C-X-C chemokine receptor type 4 (CXCR4) expression. Bone. 2017;105:122-133 pubmed publisher
Yu Z, Fan L, Li J, Ge Z, Dang X, Wang K. Lithium chloride attenuates the abnormal osteogenic/adipogenic differentiation of bone marrow-derived mesenchymal stem cells obtained from rats with steroid-related osteonecrosis by activating the β-catenin pathway. Int J Mol Med. 2015;36:1264-72 pubmed publisher
Ding Z, Huang H. Mesenchymal stem cells in rabbit meniscus and bone marrow exhibit a similar feature but a heterogeneous multi-differentiation potential: superiority of meniscus as a cell source for meniscus repair. BMC Musculoskelet Disord. 2015;16:65 pubmed publisher
Xia L, Feng B, Wang P, Ding S, Liu Z, Zhou J, et al. In vitro and in vivo studies of surface-structured implants for bone formation. Int J Nanomedicine. 2012;7:4873-81 pubmed publisher
Guo S, Guo W, Ding Y, Gong J, Zou Q, Xie D, et al. Comparative study of human dental follicle cell sheets and periodontal ligament cell sheets for periodontal tissue regeneration. Cell Transplant. 2013;22:1061-73 pubmed publisher
de Paula A, Zonari A, Martins T, Novikoff S, da Silva A, Correlo V, et al. Human serum is a suitable supplement for the osteogenic differentiation of human adipose-derived stem cells seeded on poly-3-hydroxibutyrate-co-3-hydroxyvalerate scaffolds. Tissue Eng Part A. 2013;19:277-89 pubmed publisher
Ferro F, Spelat R, D Aurizio F, Puppato E, Pandolfi M, Beltrami A, et al. Dental pulp stem cells differentiation reveals new insights in Oct4A dynamics. PLoS ONE. 2012;7:e41774 pubmed publisher
Kim H, Park S, Oh S, Kim H, Kweon O, Woo H, et al. Effect of acellular dermal matrix as a delivery carrier of adipose-derived mesenchymal stem cells on bone regeneration. J Biomed Mater Res B Appl Biomater. 2012;100:1645-53 pubmed publisher
Park B, Kang E, Byun J, Son M, Kim H, Hah Y, et al. In vitro and in vivo osteogenesis of human mesenchymal stem cells derived from skin, bone marrow and dental follicle tissues. Differentiation. 2012;83:249-59 pubmed publisher
Rodrigues M, Martins A, Dias I, Viegas C, Neves N, Gomes M, et al. Synergistic effect of scaffold composition and dynamic culturing environment in multilayered systems for bone tissue engineering. J Tissue Eng Regen Med. 2012;6:e24-30 pubmed publisher
Abudusaimi A, Aihemaitijiang Y, Wang Y, Cui L, Maimaitiming S, Abulikemu M. Adipose-derived stem cells enhance bone regeneration in vascular necrosis of the femoral head in the rabbit. J Int Med Res. 2011;39:1852-60 pubmed
Grzibovskis M, Urtane I, Pilmane M, Jankovska I. Specific signaling molecule expressions in the interradicular septum in different age groups. Stomatologija. 2011;13:81-6 pubmed
Zou D, Han W, You S, Ye D, Wang L, Wang S, et al. In vitro study of enhanced osteogenesis induced by HIF-1?-transduced bone marrow stem cells. Cell Prolif. 2011;44:234-43 pubmed publisher
Zhu H, Cao B, Zhen Z, Laxmi A, Li D, Liu S, et al. Controlled growth and differentiation of MSCs on grooved films assembled from monodisperse biological nanofibers with genetically tunable surface chemistries. Biomaterials. 2011;32:4744-52 pubmed publisher
Kearney C, Lee J, Padera R, Hsu H, Spector M. Extracorporeal shock wave-induced proliferation of periosteal cells. J Orthop Res. 2011;29:1536-43 pubmed publisher
Juhásová J, Juhás S, Klima J, Strnádel J, Holubova M, Motlik J. Osteogenic differentiation of miniature pig mesenchymal stem cells in 2D and 3D environment. Physiol Res. 2011;60:559-71 pubmed
Reichert J, Quent V, Nöth U, Hutmacher D. Ovine cortical osteoblasts outperform bone marrow cells in an ectopic bone assay. J Tissue Eng Regen Med. 2011;5:831-44 pubmed publisher
Ferro F, Falini G, Spelat R, D Aurizio F, Puppato E, Pandolfi M, et al. Biochemical and biophysical analyses of tissue-engineered bone obtained from three-dimensional culture of a subset of bone marrow mesenchymal stem cells. Tissue Eng Part A. 2010;16:3657-67 pubmed publisher
Park J, Yang H, Jeon S, Woo D, Na K, Park K. Osteogenic differentiation of human mesenchymal stem cells using RGD-modified BMP-2 coated microspheres. Biomaterials. 2010;31:6239-48 pubmed publisher
Rhee S, Ji Y, Gharibjanian N, Dhong E, Park S, Yoon E. In vivo evaluation of mixtures of uncultured freshly isolated adipose-derived stem cells and demineralized bone matrix for bone regeneration in a rat critically sized calvarial defect model. Stem Cells Dev. 2011;20:233-42 pubmed publisher
Gondi C, Veeravalli K, Gorantla B, Dinh D, Fassett D, Klopfenstein J, et al. Human umbilical cord blood stem cells show PDGF-D-dependent glioma cell tropism in vitro and in vivo. Neuro Oncol. 2010;12:453-65 pubmed publisher
Mizrak S, Chikhovskaya J, Sadri Ardekani H, van Daalen S, Korver C, Hovingh S, et al. Embryonic stem cell-like cells derived from adult human testis. Hum Reprod. 2010;25:158-67 pubmed publisher
Rattazzi M, Iop L, Faggin E, Bertacco E, Zoppellaro G, Baesso I, et al. Clones of interstitial cells from bovine aortic valve exhibit different calcifying potential when exposed to endotoxin and phosphate. Arterioscler Thromb Vasc Biol. 2008;28:2165-72 pubmed publisher
Donzelli E, Salvade A, Mimo P, Vigano M, Morrone M, Papagna R, et al. Mesenchymal stem cells cultured on a collagen scaffold: In vitro osteogenic differentiation. Arch Oral Biol. 2007;52:64-73 pubmed
product information
CatalogNumber :
ab13418
ItemName :
Anti-Osteocalcin antibody [OC4-30]
Product Type :
Antibody
Host Species :
Mouse
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
OC4-30
Size :
50 µg
SpeciesSummary :
Cow, Dog, Goat, Hu, Pig, Rat, Rb, Shp
Purity :
Protein A purified
Application Summary :
ICC/IF, IHC-Fr, IHC-P, sELISA, WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK