| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; human; 1:1000; loading ...; fig 2c
| Zou Y, Li H, Graham E, Deik A, Eaton J, Wang W, et al. Cytochrome P450 oxidoreductase contributes to phospholipid peroxidation in ferroptosis. Nat Chem Biol. 2020;16:302-309 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:2000; loading ...; fig 1i
- western blot; human; loading ...; fig 2
| Wei X, Xue M, Kang C, Gao L, Zhang M, Ma C, et al. Increased NOX1 and DUOX2 expression in the colonic mucosa of patients with chronic functional constipation. Medicine (Baltimore). 2022;101:e30028 pubmed publisher |
- immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 8i
- western blot; mouse; 1:1000; loading ...; fig 8g
| Wan L, Bai X, Zhou Q, Chen C, Wang H, Liu T, et al. The advanced glycation end-products (AGEs)/ROS/NLRP3 inflammasome axis contributes to delayed diabetic corneal wound healing and nerve regeneration. Int J Biol Sci. 2022;18:809-825 pubmed publisher |
- western blot; rat; 1:500; fig 2g
| Sayour A, Ruppert M, Olah A, Benke K, Barta B, Zsáry E, et al. Left Ventricular SGLT1 Protein Expression Correlates with the Extent of Myocardial Nitro-Oxidative Stress in Rats with Pressure and Volume Overload-Induced Heart Failure. Antioxidants (Basel). 2021;10: pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig 1e
| Casagrande V, Iuliani G, Menini S, Pugliese G, Federici M, Menghini R. Restoration of renal TIMP3 levels via genetics and pharmacological approach prevents experimental diabetic nephropathy. Clin Transl Med. 2021;11:e305 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 6f
| Huang S, You S, Qian J, Dai C, Shen S, Wang J, et al. Myeloid differentiation 2 deficiency attenuates AngII-induced arterial vascular oxidative stress, inflammation, and remodeling. Aging (Albany NY). 2021;13:4409-4427 pubmed publisher |
- immunohistochemistry; mouse; 1:1000; loading ...; fig 7b
| Xiao L, Zhong M, Huang Y, Zhu J, Tang W, Li D, et al. Puerarin alleviates osteoporosis in the ovariectomy-induced mice by suppressing osteoclastogenesis via inhibition of TRAF6/ROS-dependent MAPK/NF-κB signaling pathways. Aging (Albany NY). 2020;12:21706-21729 pubmed publisher |
- western blot; human; loading ...; fig 2d
| Gao X, Zhao L, Liu S, Li Y, Xia S, Chen D, et al. γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A. Mol Cell. 2019;76:857-871.e9 pubmed publisher |
- immunocytochemistry; human; loading ...; fig s6b
| Pan C, Jin L, Wang X, Li Y, Chun J, Boese A, et al. Inositol-triphosphate 3-kinase B confers cisplatin resistance by regulating NOX4-dependent redox balance. J Clin Invest. 2019;129:2431-2445 pubmed publisher |
- immunohistochemistry; human; loading ...; fig 1b
- western blot; human; loading ...; fig 3a
| Zhang J, Li H, Wu Q, Chen Y, Deng Y, Yang Z, et al. Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growth. Redox Biol. 2019;22:101116 pubmed publisher |
- western blot; rat; loading ...; fig 5b
| Wang Z, Ding Y, Wang X, Lu S, Wang C, He C, et al. Pseudolaric acid B triggers ferroptosis in glioma cells via activation of Nox4 and inhibition of xCT. Cancer Lett. 2018;428:21-33 pubmed publisher |
- western blot; mouse; loading ...; fig EV4a
| Hammers D, Merscham Banda M, Hsiao J, ENGST S, Hartman J, Sweeney H. Supraphysiological levels of GDF11 induce striated muscle atrophy. EMBO Mol Med. 2017;9:531-544 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig S3b; 3c
- immunohistochemistry - paraffin section; mouse; fig 2f
- western blot; mouse; loading ...; fig S4c
| Ju H, Ying H, Tian T, Ling J, Fu J, Lu Y, et al. Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma. Nat Commun. 2017;8:14437 pubmed publisher |
- western blot; human; loading ...; fig 1b
| Zeng C, Wu Q, Wang J, Yao B, Ma L, Yang Z, et al. NOX4 supports glycolysis and promotes glutamine metabolism in non-small cell lung cancer cells. Free Radic Biol Med. 2016;101:236-248 pubmed publisher |
- western blot; mouse; 1:2500; fig st2
| Gharib M, Tao H, Fungwe T, Hajri T. Cluster Differentiating 36 (CD36) Deficiency Attenuates Obesity-Associated Oxidative Stress in the Heart. PLoS ONE. 2016;11:e0155611 pubmed publisher |
- western blot; mouse; fig 5
| Liu S, Wu C, Huang K, Wang C, Guan S, Chen L, et al. C/EBP homologous protein (CHOP) deficiency ameliorates renal fibrosis in unilateral ureteral obstructive kidney disease. Oncotarget. 2016;7:21900-12 pubmed publisher |
| Besnier M, Finemore M, Yu C, Kott K, Vernon S, Seebacher N, et al. Patient Endothelial Colony-Forming Cells to Model Coronary Artery Disease Susceptibility and Unravel the Role of Dysregulated Mitochondrial Redox Signalling. Antioxidants (Basel). 2021;10: pubmed publisher |
| Bautista Pérez R, Cano Martínez A, Gutiérrez Velázquez E, Martínez Rosas M, Pérez Gutiérrez R, Jiménez Gómez F, et al. Spinach Methanolic Extract Attenuates the Retinal Degeneration in Diabetic Rats. Antioxidants (Basel). 2021;10: pubmed publisher |
| Li Z, Ge M, Yuan Z. MicroRNA-182-5p protects human lens epithelial cells against oxidative stress-induced apoptosis by inhibiting NOX4 and p38 MAPK signalling. BMC Ophthalmol. 2020;20:233 pubmed publisher |
| Chatterjee A, Kosmacek E, Shrishrimal S, McDonald J, Oberley Deegan R. MnTE-2-PyP, a manganese porphyrin, reduces cytotoxicity caused by irradiation in a diabetic environment through the induction of endogenous antioxidant defenses. Redox Biol. 2020;34:101542 pubmed publisher |
| Liu X, Zhong L, Li P, Zhao P. MicroRNA-100 Enhances Autophagy and Suppresses Migration and Invasion of Renal Cell Carcinoma Cells via Disruption of NOX4-Dependent mTOR Pathway. Clin Transl Sci. 2020;: pubmed publisher |
| Ghosh A, Rao V, Wisniewski V, Zigrossi A, Floss J, Koulen P, et al. Differential Activation of Glioprotective Intracellular Signaling Pathways in Primary Optic Nerve Head Astrocytes after Treatment with Different Classes of Antioxidants. Antioxidants (Basel). 2020;9: pubmed publisher |
| Chen Y, Liu Q, Shan Z, Zhao Y, Li M, Wang B, et al. The protective effect and mechanism of catalpol on high glucose-induced podocyte injury. BMC Complement Altern Med. 2019;19:244 pubmed publisher |
| He C, Larson Casey J, Davis D, Hanumanthu V, Longhini A, Thannickal V, et al. NOX4 modulates macrophage phenotype and mitochondrial biogenesis in asbestosis. JCI Insight. 2019;4: pubmed publisher |
| Yu M, Li X, Li Q, Mo S, Ni Y, Han F, et al. SAA1 increases NOX4/ROS production to promote LPS-induced inflammation in vascular smooth muscle cells through activating p38MAPK/NF-κB pathway. BMC Mol Cell Biol. 2019;20:15 pubmed publisher |
| Hagenbeek T, Webster J, Kljavin N, Chang M, Pham T, Lee H, et al. The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors. Sci Signal. 2018;11: pubmed publisher |
| Zhang Y, Ren S, Gu Y, Wang J, Liu Z, Zhang Z. Taurine Attenuates Calpain-2 Induction and a Series of Cell Damage via Suppression of NOX-Derived ROS in ARPE-19 Cells. Oxid Med Cell Longev. 2018;2018:4596746 pubmed publisher |
