This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Abcam
other brands :
Epitomics, Ascent Scientific, MitoSciences
product type :
antibody
product name :
Anti-NOX2/gp91phox antibody [EPR6991]
catalog :
ab129068
quantity :
10 µl, 100 µl
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
EPR6991
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:5000; loading ...; fig 6f
Rangan P, Lobo F, Parrella E, Rochette N, Morselli M, Stephen T, et al. Fasting-mimicking diet cycles reduce neuroinflammation to attenuate cognitive decline in Alzheimer's models. Cell Rep. 2022;40:111417 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 8i
  • western blot; mouse; 1:1000; loading ...; fig 8g
Wan L, Bai X, Zhou Q, Chen C, Wang H, Liu T, et al. The advanced glycation end-products (AGEs)/ROS/NLRP3 inflammasome axis contributes to delayed diabetic corneal wound healing and nerve regeneration. Int J Biol Sci. 2022;18:809-825 pubmed publisher
  • western blot; mouse; 1:200; loading ...; fig s2h
Saiyang X, QingQing W, Man X, Chen L, Min Z, Yun X, et al. Activation of Toll-like receptor 7 provides cardioprotection in septic cardiomyopathy-induced systolic dysfunction. Clin Transl Med. 2021;11:e266 pubmed publisher
  • western blot; human; loading ...; fig 7c
Wu Z, Zhao X, Banaszak L, Gutierrez Rodrigues F, Keyvanfar K, Gao S, et al. CRISPR/Cas9-mediated ASXL1 mutations in U937 cells disrupt myeloid differentiation. Int J Oncol. 2018;52:1209-1223 pubmed publisher
  • western blot; rat; loading ...; fig 6
Zhai L, Liu M, Wang T, Zhang H, Li S, Guo Y. Picroside II protects the blood-brain barrier by inhibiting the oxidative signaling pathway in cerebral ischemia-reperfusion injury. PLoS ONE. 2017;12:e0174414 pubmed publisher
  • western blot; mouse; 1:2500; fig st2
Gharib M, Tao H, Fungwe T, Hajri T. Cluster Differentiating 36 (CD36) Deficiency Attenuates Obesity-Associated Oxidative Stress in the Heart. PLoS ONE. 2016;11:e0155611 pubmed publisher
  • western blot; human; 1:1000; fig 4
Dvash E, Har Tal M, Barak S, Meir O, Rubinstein M. Leukotriene C4 is the major trigger of stress-induced oxidative DNA damage. Nat Commun. 2015;6:10112 pubmed publisher
  • immunoprecipitation; mouse; fig 6
  • immunocytochemistry; mouse; 1:250; fig 6
Graham D, Becker C, Doan A, Goel G, Villablanca E, Knights D, et al. Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst. Nat Commun. 2015;6:7838 pubmed publisher
  • western blot; mouse; 1:1000; fig 5a
Lee J, Kim H, Han J, Kim Y, Son C. Anti-fatigue effect of Myelophil in a chronic forced exercise mouse model. Eur J Pharmacol. 2015;764:100-8 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Heiserman J, Chen L, Kim B, Kim S, Tran A, Siebenborn N, et al. TLR4 mutation and HSP60-induced cell death in adult mouse cardiac myocytes. Cell Stress Chaperones. 2015;20:527-35 pubmed publisher
  • western blot; human
Jadhav V, Krause K, Singh S. HIV-1 Tat C modulates NOX2 and NOX4 expressions through miR-17 in a human microglial cell line. J Neurochem. 2014;131:803-15 pubmed publisher
Besnier M, Finemore M, Yu C, Kott K, Vernon S, Seebacher N, et al. Patient Endothelial Colony-Forming Cells to Model Coronary Artery Disease Susceptibility and Unravel the Role of Dysregulated Mitochondrial Redox Signalling. Antioxidants (Basel). 2021;10: pubmed publisher
Birk M, Baum E, Zadeh J, Manicam C, Pfeiffer N, Patzak A, et al. Angiotensin II Induces Oxidative Stress and Endothelial Dysfunction in Mouse Ophthalmic Arteries via Involvement of AT1 Receptors and NOX2. Antioxidants (Basel). 2021;10: pubmed publisher
Yan J, Huang J, Liu A, Wu J, Fan H, Shen M, et al. Atorvastatin improves motor function, anxiety and depression by NOX2-mediated autophagy and oxidative stress in MPTP-lesioned mice. Aging (Albany NY). 2020;13:831-845 pubmed publisher
Chatterjee A, Kosmacek E, Shrishrimal S, McDonald J, Oberley Deegan R. MnTE-2-PyP, a manganese porphyrin, reduces cytotoxicity caused by irradiation in a diabetic environment through the induction of endogenous antioxidant defenses. Redox Biol. 2020;34:101542 pubmed publisher
Henríquez Olguín C, Knudsen J, Raun S, Li Z, Dalbram E, Treebak J, et al. Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise. Nat Commun. 2019;10:4623 pubmed publisher
Cho R, Yang C, Tseng H, Hsiao L, Lin C, Yang C. Haem oxygenase-1 up-regulation by rosiglitazone via ROS-dependent Nrf2-antioxidant response elements axis or PPARγ attenuates LPS-mediated lung inflammation. Br J Pharmacol. 2018;175:3928-3946 pubmed publisher
Harms J, Kuczmarski J, Kim J, Thomas G, Kaufman M. The role played by oxidative stress in evoking the exercise pressor reflex in health and simulated peripheral artery disease. J Physiol. 2017;595:4365-4378 pubmed publisher
McLaughlin D, Zhao Y, O Neill K, Edgar K, Dunne P, Kearney A, et al. Signalling mechanisms underlying doxorubicin and Nox2 NADPH oxidase-induced cardiomyopathy: involvement of mitofusin-2. Br J Pharmacol. 2017;174:3677-3695 pubmed publisher
Yu P, Li J, Jiang J, Zhao Z, Hui Z, Zhang J, et al. A dual role of transient receptor potential melastatin 2 channel in cytotoxicity induced by silica nanoparticles. Sci Rep. 2015;5:18171 pubmed publisher
product information
CatalogNumber :
ab129068
ItemName :
Anti-NOX2/gp91phox antibody [EPR6991]
Category :
Antibody
Host :
Rabbit
Clonality :
Monoclonal
Conjugate :
Unconjugated
Clone Name :
EPR6991
Size :
10 µl, 100 µl
SpeciesSummary :
Hu, Ms, Rat
Application Summary :
WB
company information
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB20AX
https://www.abcam.com
888-7722226
headquarters: UK